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Cited by 45Maternal and Perinatal Health InterventionsPreterm Birth and ChorioamnionitisNeuroendocrine regulation and behavior

Effect of nipple stimulation on uterine activity and on plasma levels of oxytocin in full term, healthy, pregnant women

Christensson, Kyllike, Nilsson, Bo A., Stock, Solveig, Matthiesen, Ann Sofie, Uvnäs‐Moberg, Kerstin·1989·Acta Obstetricia Et Gynecologica Scandinavica
DOI 10.3109/00016348909020990
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Abstract

The effect of nipple stimulation on uterine activity, foetal heart rate and plasma oxytocin level in healthy full term pregnant women was studied. Ten women in weeks 38-39 of pregnancy stimulated their nipples for 30 min. Nine of the ten experienced uterine contractions. One woman showed signs uterine hyperactivity (frequent contractions) and foetal heart rate decelerations. Blood samples were drawn at 15 s intervals during 5-6 contractions and oxytocin levels were measured with radioimmunoassay. Oxytocin levels rose significantly during the nipple stimulation and short bursts of oxytocin were recorded during contractions. Nipple stimulation has been used to induce labour and our data may suggest that oxytocin released in response to such stimulation is responsible for the contractions induced.

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Crossref · 10.3109/00016348909020990

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  • OT is released peripherally during labor and helps evoke uterine contractions; release is also induced by vaginocervical stimulation and nipple stimulation, which induces milk letdown.

    “OT is released peripherally during labor and helps to evoke uterine contractions (Burbach et al 2005). The release of OT is also induced by vaginocervical stimulation, either from birth or from copulation. OT is also released peripherally in response to nipple stimulation, which, in the context of nursing, induces the letdown of milk from the mammary glands (Christensson et al 1989).”

    From The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction (2012) · cites this paper as Christensson et al 1989

  • OT is released in humans during hugging, touching, massage, nipple stimulation, and orgasm, and promotes increased eye gaze, trust, and attention to emotional cues.

    “OT is released in humans during hugging, touching, massage, nipple stimulation, and orgasm (Carmichael et al 1987; Christensson et al 1989; Turner et al 1999; Light et al 2000; Light et al 2005), and promotes increased eye gaze, trust, and attention to emotional cues (Kosfeld et al 2005; Domes et al 2007; Guastella et al 2008; Andari et al 2010).”

    From The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction (2012) · cites this paper as Christensson et al 1989

  • Suckling or nipple stimulation increases plasma oxytocin in rats and in full-term pregnant women.

    “Likewise, others have found that suckling or nipple stimulation increases plasma oxytocin in rats (Neumann et al., 2000) as well as in full-term pregnant women (Christensson et al., 1989).”

    From Endogenous peripheral oxytocin measures can give insight into the dynamics of social relationships: a review (2014) · cites this paper as Christensson et al., 1989

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Authors
Christensson, K., Nilsson, B. A., Stock, S., Matthiesen, A. S., & Uvnäs‐Moberg, K.
Affiliations
  • Karolinska University Hospital (SE)
  • Stockholm South General Hospital (SE)
  • Karolinska Institutet (SE)
  • Stockholm University (SE)
Corresponding author
Christensson, Kyllike
Venue
Acta Obstetricia Et Gynecologica Scandinavica
Publisher
Wiley
Published
1989-01
Volume
68
Issue
3
Pages
205-210
ISSN
  • 0001-6349 (ISSN-L)
  • 1600-0412
DOI
10.3109/00016348909020990
OpenAlex
W2146660639
Cited by
45
References
17
Citations by year
2025: 1 · 2023: 3 · 2022: 1 · 2021: 2 · 2020: 3 · 2019: 1 · 2018: 3 · 2016: 2 · 2015: 3 · 2014: 3 · 2013: 3 · 2012: 3
FWCI
0.00
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 8045 d)
Locations
  • Acta Obstetricia Et Gynecologica Scandinavica (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
  • Health Sciences › Medicine › Epidemiology › Preterm Birth and Chorioamnionitis
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
Keywords
nipple stimulation, oxytocin, uterine contraction, uterine contractility, term pregnancy, labor induction, fetal heart rate, uterine hyperactivity, plasma oxytocin
MeSH terms
Adult, Breast, Female, Heart Rate, Fetal, Humans, Nipples, Oxytocin, Pregnancy, Radioimmunoassay, Uterine Contraction

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