Mismatch negativity-a unique measure of sensory processing in audition.
Abstract
Physically deviant auditory stimuli occurring among frequent ("standard") stimuli (e.g., tones or phonetic stimuli) elicit the mismatch negativity (MMN) of the auditory event-related potential (ERP). The MMN is presumably generated by a mismatch process between the sensory input from a deviant stimulus and a neural sensory-memory trace representing the physical features of the standard stimulus. This process, as well as sensory analysis of auditory input and its encoding into the memory trace, appear to be automatic since the MMN is elicited even by changes in unattended auditory stimuli. Therefore the MMN indirectly provides a unique, objective measure of the central representation of a sound. This opens new possibilities for basic research as well as clinical and other applications.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Several neurophysiological studies in PTSD reveal that PTSD is often associated with extreme sensory processing patterns, including sensory hypersensitivity and hyposensitivity to stimuli associated with traumatic memories.
“Indeed, several neurophysiological studies in PTSD reveal that PTSD is often associated with extreme sensory processing patterns, including sensory hypersensitivity and hyposensitivity to stimuli associated with traumatic memories (such as specific sounds, images, touch stimulation) (Näätänen and Alho, 1995; Grillon and Morgan, 1999; Shalev et al., 2000; Engel-Yeger et al., 2013).”
From How Processing of Sensory Information From the Internal and External Worlds Shape the Perception and Engagement With the World in the Aftermath of Trauma: Implications for PTSD (2021) · cites this paper as Näätänen and Alho, 1995
Cites
Attentive novelty detection in humans is governed by pre-attentive sensory memory
Tiitinen, H., May, P., Reinikainen, K., & Näätänen, R. (1994) · Nature · doi:10.1038/372090a0 · Cited by 637 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
The mismatch negativity: a review of underlying mechanisms
Garrido, M. I., Kilner, J. M., Stephan, K. E., & Friston, K. J. (2009) · Clinical Neurophysiology · doi:10.1016/j.clinph.2008.11.029 · Cited by 1,441 · see citing works
“Barely discriminable tones elicit a later MMN peaking at about 200–300 ms (Näätänen and Alho, 1995).”
BackgroundMismatch negativity (MMN), the deviance-elicited auditory deflection, explained
May, P. J. C., & Tiitinen, H. (2010) · Psychophysiology · doi:10.1111/j.1469-8986.2009.00856.x · Cited by 549 · see citing works
Barry, R. J., Johnstone, S. J., & Clarke, A. R. (2003) · Clinical Neurophysiology · doi:10.1016/s1388-2457(02)00363-2 · Cited by 434 · see citing works
Harricharan, S., McKinnon, M. C., & Lanius, R. A. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.625490 · Cited by 110 · see citing works
Enhanced deviant responses in patterned relative to random sound sequences
Southwell, R., & Chait, M. (2018) · Cortex · doi:10.1016/j.cortex.2018.08.032 · Cited by 80 · see citing works
The sensory profile of people with post-traumatic stress symptoms.
Engel-Yeger, B., Palgy-Levin, D., & Lev-Wiesel, R. (2013) · Occupational Therapy in Mental Health · doi:10.1080/0164212x.2013.819466 · Cited by 84 · see citing works
Advances in Electrophysiological Research
Kamarajan, C. (2015) · Alcohol Research: Current Reviews · doi:10.35946/arcr.v37.1.05 · Cited by 72 · see citing works
Simultaneous fMRI-EEG-DTI recording of MMN in patients with schizophrenia
Kirino, E., Hayakawa, Y., Inami, R., Inoue, R., & Aoki, S. (2019) · PLoS ONE · doi:10.1371/journal.pone.0215023 · Cited by 22 · see citing works
- Authors
- Näätänen, R., & Alho, K.
- Affiliations
- University of Helsinki (FI)
- ORCID
- Alho, Kimmo
- Venue
- International Journal of Neuroscience
- Publisher
- Informa UK Limited
- Published
- 1995-01
- Volume
- 80
- Issue
- 1-4
- Pages
- 317-337
- ISSN
- 0020-7454 (ISSN-L)
- 1543-5245
- OpenAlex
- W2085306469
- Cited by
- 340
- References
- 1
- Citations by year
- 2026: 8 · 2025: 8 · 2024: 10 · 2023: 10 · 2022: 11 · 2021: 11 · 2020: 18 · 2019: 15 · 2018: 11 · 2017: 8 · 2016: 8 · 2015: 12 · 2014: 19 · 2013: 23 · 2012: 9
- FWCI
- 4.30
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
- Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- mismatch negativity, auditory event-related potentials, auditory sensory memory, automatic auditory processing
- MeSH terms
- Adolescent, Adult, Age Factors, Aged, Aging, Auditory Perception, Automatism, Blindness, Brain, Evoked Potentials, Auditory, Humans, Learning, Memory, Middle Aged, Neural Pathways, Neuronal Plasticity
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
