Uterine contractions in endometriosis: Effects of operative and danazol treatment
Abstract
SummaryTo study uterine contractions in proved endometriosis and the effects of operative and danazol treatment, intrauterine pressures at the isthmus and fundus level were recorded 27 times in 17 women with endometriosis and 20 times in 10 healthy women. In endometriosis a pattern of hypercontractility in the form of increased resting pressure was observed both during the luteal phase of the cycle and during menstruation, whereas the frequency of fundal contractions during the luteal phase was decreased. This pattern of uterine contractions was not affected by operative or danazol (600 mg/day) treatment, although these treatments provided symptomatic relief. These data suggest there is uterine hypercontractility in endometriosis, which seems to be of minor importance in causing symptoms.
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Uterine function of rapid and directed sperm transport into the dominant tube is dysfunctional in women with endometriosis and is characterized by hyper- and dysperistalsis.
“The uterine function of rapid and directed sperm transport into the ‘dominant tube’ is dysfunctional in women with endometriosis and is characterized by hyper- and dysperistalsis [27–32].”
From The pathophysiology of endometriosis and adenomyosis, tissue injury and repair (2009) · cites this paper as [27]
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- Authors
- Mäkäräinen, L.
- Affiliations
- University of Oulu (FI)
- Corresponding author
- Mäkäräinen, L.
- Venue
- Journal of Obstetrics and Gynaecology
- Publisher
- Informa UK Limited
- Published
- 1988-01
- Volume
- 9
- Issue
- 2
- Pages
- 134-138
- ISSN
- 0144-3615 (ISSN-L)
- 1364-6893
- OpenAlex
- W2133328537
- Cited by
- 22
- References
- 17
- Citations by year
- 2022: 1 · 2019: 1 · 2017: 1
- FWCI
- 0.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Obstetrics and Gynaecology (publishedVersion)
- Funders
- Suomen Lääketieteen Säätiö
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Menstrual Health and Disorders
- Keywords
- endometriosis, uterine contraction, uterine hypercontractility, intrauterine pressure, danazol, surgical treatment, luteal phase, menstruation, endometriosis symptoms
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