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Progress of new label-free techniques for biosensors: a review

Sang, Shengbo, Wang, Yajun, Feng, Qiliang, Wei, Ye, Ji, Jianlong, Zhang, Wendong·2015·Critical Reviews in Biotechnology

Abstract

The detection techniques used in biosensors can be broadly classified into label-based and label-free. Label-based detection relies on the specific properties of labels for detecting a particular target. In contrast, label-free detection is suitable for the target molecules that are not labeled or the screening of analytes which are not easy to tag. Also, more types of label-free biosensors have emerged with developments in biotechnology. The latest developed techniques in label-free biosensors, such as field-effect transistors-based biosensors including carbon nanotube field-effect transistor biosensors, graphene field-effect transistor biosensors and silicon nanowire field-effect transistor biosensors, magnetoelastic biosensors, optical-based biosensors, surface stress-based biosensors and other type of biosensors based on the nanotechnology are discussed. The sensing principles, configurations, sensing performance, applications, advantages and restriction of different label-free based biosensors are considered and discussed in this review. Most concepts included in this survey could certainly be applied to the development of this kind of biosensor in the future.

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Metadata

Authors
Sang, S., Wang, Y., Feng, Q., Wei, Y., Ji, J., & Zhang, W.
Venue
Critical Reviews in Biotechnology
Published
2015-01-22
Volume
36
Issue
3
Pages
1-17
ISSN
  • 0738-8551 (ISSN-L)
  • 1549-7801
OpenAlex
W2163618583
Cited by
272
References
5
FWCI
6.74
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Progress of new label-free techniques for biosensors: a review. https://app.cochat.ai/papers/10.3109/07388551.2014.991270
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Sang, S., Wang, Y., Feng, Q., Wei, Y., Ji, J., & Zhang, W. (2015). Progress of new label-free techniques for biosensors: a review. Critical Reviews in Biotechnology. https://doi.org/10.3109/07388551.2014.991270

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