The TGF-β superfamily cytokine, MIC-1/GDF15: A pleotrophic cytokine with roles in inflammation, cancer and metabolism

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin

Tanno, T., Bhanu, N. V., Oneal, P. A., Goh, S.-H., Staker, P., Lee, Y. T., Moroney, J. W., Reed, C. H., Luban, N. L., Wang, R.-H., et al. (2007) · Nature Medicine · doi:10.1038/nm1629 · Cited by 854

Substantial Genetic Influence on Cognitive Abilities in Twins 80 or More Years Old

McClearn, G. E., Johansson, B. E. A., Berg, S., Pedersen, N. L., Ahern, F. M., Petrill, S. A., & Plomin, R. J. (1997) · Science · doi:10.1126/science.276.5318.1560 · Cited by 727

Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1

Johnen, H., Lin, S., Kuffner, T., Brown, D. A., Tsai, V. W.-W., Bauskin, A. R., Wu, L., Pankhurst, G., Jiang, L., Junankar, S., et al. (2007) · Nature Medicine · doi:10.1038/nm1677 · Cited by 612

GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice

Kempf, T., Zarbock, A., Widera, C., Butz, S., Stadtmann, A., Rossaint, J., Bolomini-Vittori, M., Korf-Klingebiel, M., Napp, L. C., Hansen, B., et al. (2011) · Nature Medicine · doi:10.1038/nm.2354 · Cited by 518

Large-Scale Delineation of Secreted Protein Biomarkers Overexpressed in Cancer Tissue and Serum

Welsh, J. B., Sapinoso, L. M., Kern, S. G., Brown, D. A., Liu, T., Bauskin, A. R., Ward, R. L., Hawkins, N. J., Quinn, D. I., Russell, P. J., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0530278100 · Cited by 503

Cyclooxygenase Inhibitors Regulate the Expression of a TGF-β Superfamily Member That Has Proapoptotic and Antitumorigenic Activities

Baek, S. J., Kim, K. S., Nixon, J. B., Wilson, L. C., & Eling, T. E. (2001) · Molecular Pharmacology · doi:10.1124/mol.59.4.901 · Cited by 402

Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells

Tanno, T., Porayette, P., Sripichai, O., Noh, S.-J., Byrnes, C., Bhupatiraju, A., Lee, Y. T., Goodnough, J. B., Harandi, O., Ganz, T., et al. (2009) · Blood · doi:10.1182/blood-2008-12-195503 · Cited by 352

Macrophage inhibitory cytokine‐1 (MIC‐1/GDF15): a new marker of all‐cause mortality

Wiklund, F. E., Bennet, A. M., Magnusson, P. K. E., Eriksson, U. K., Lindmark, F., Wu, L., Yaghoutyfam, N., Marquis, C. P., Stattin, P. E., Pedersen, N. L., et al. (2010) · Aging Cell · doi:10.1111/j.1474-9726.2010.00629.x · Cited by 293

Circulating Concentrations of Growth-Differentiation Factor 15 in Apparently Healthy Elderly Individuals and Patients with Chronic Heart Failure as Assessed by a New Immunoradiometric Sandwich Assay

Kempf, T., Horn-Wichmann, R., Brabant, G. E., Peter, T., Allhoff, T., Klein, G. G., Drexler, H., Johnston, N., Wallentin, L. C., & Wollert, K. C. (2006) · Clinical Chemistry · doi:10.1373/clinchem.2006.076828 · Cited by 290

Serum Macrophage Inhibitory Cytokine 1 as a Marker of Pancreatic and Other Periampullary Cancers

Koopmann, J., Buckhaults, P., Brown, D. A., ZAHURAK, M. L., Sato, N., Fukushima, N., Sokoll, L. J., Chan, D. W., Yeo, C. J., Hruban, R. H., et al. (2004) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-03-0165 · Cited by 274

Macrophage inhibitory cytokine-1 versus carbohydrate antigen 19–9 as a biomarker for diagnosis of pancreatic cancer

Yang, Y., Yan, S., Tian, H., & Bao, Y. (2018) · Medicine · doi:10.1097/md.0000000000009994 · Cited by 31

Diagnostic utility of GDF15 in neurodegenerative diseases: A systematic review and meta‐analysis

Xue, X., Tao, L., Su, D., Guo, C., & Liu, H. (2022) · Brain and Behavior · doi:10.1002/brb3.2502 · Cited by 31

Macrophage Inhibitory Cytokine 1 Biomarker Serum Immunoassay in Combination with PSA Is a More Specific Diagnostic Tool for Detection of Prostate Cancer

Li, J., Veltri, R. W., Yuan, Z., Christudass, C. S., & Mandecki, W. (2015) · PLoS ONE · doi:10.1371/journal.pone.0122249 · Cited by 30

Increased Serum Level of Growth Differentiation Factor 15 ( GDF ‐15) is Associated with Coronary Artery Disease

Wang, X., Chen, L., & Zhang, Q. (2016) · Cardiovascular Therapeutics · doi:10.1111/1755-5922.12184 · Cited by 30

Modulatory Effects of Estradiol and Its Mixtures with Ligands of GPER and PPAR on MAPK and PI3K/Akt Signaling Pathways and Tumorigenic Factors in Mouse Testis Explants and Mouse Tumor Leydig Cells

Górowska-Wójtowicz, E., Duliban, M., Kotula‐Balak, M., & Bilińska, B. (2022) · Biomedicines · doi:10.3390/biomedicines10061390 · Cited by 29

GDF15: a potential therapeutic target for type 1 diabetes

Sarkar, S., Melchior, J., Henry, H. R., Syed, F., Mirmira, R. G., Nakayasu, E. S., & Metz, T. (2022) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2022.2029410 · Cited by 31

Macrophage Inhibitory Cytokine-1 (MIC-1/GDF15) Gene Deletion Promotes Cancer Growth in TRAMP Prostate Cancer Prone Mice

Husaini, Y., Lockwood, G. P., Nguyen, T. V., Tsai, V. W.-W., Mohammad, M. G., Russell, P. J., Brown, D. A., & Breit, S. N. (2015) · PLoS ONE · doi:10.1371/journal.pone.0115189 · Cited by 27

Growth Differentiation Factor-15–Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells

Muralidharan, A. R., Maddala, R., Skiba, N. P., & Rao, P. V. (2016) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.16-20671 · Cited by 27

Serum Growth Differentiation Factor 15 in Parkinson Disease

Yao, X., Wang, D., Zhang, L., Wang, L., Zhao, Z., Chen, S., Wang, X., Yue, T., & Liu, Y. (2017) · Neurodegenerative Diseases · doi:10.1159/000477349 · Cited by 27

Further evidence of accelerated aging in bipolar disorder: Focus on GDF-15

Yang, F., Barbosa, I. G., Vieira, É. L. M., Bauer, M. E., Rocha, N. P., & Teixeira, A. L. (2018) · Translational Neuroscience · doi:10.1515/tnsci-2018-0004 · Cited by 28

Inhibition of Breast Cancer Cell Invasion by Ras Suppressor-1 (RSU-1) Silencing Is Reversed by Growth Differentiation Factor-15 (GDF-15)

Gkretsi, V., Louca, M., Stylianou, A., Minadakis, G., Spyrou, G. M., & Stylianopoulos, T. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20010163 · Cited by 26

Single nuclei RNA sequencing of the rat AP and NTS following GDF15 treatment

Reiner, B. C., Crist, R. C., Borner, T., Doyle, R. P., Hayes, M. R., & Jonghe, B. C. D. (2021) · Molecular Metabolism · doi:10.1016/j.molmet.2021.101422 · Cited by 26

GDF15 Supports the Inflammatory Response of PdL Fibroblasts Stimulated by P. gingivalis LPS and Concurrent Compression

Stemmler, A., Symmank, J., Steinmetz, J. L., von Brandenstein, K., Hennig, C., & Jacobs, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222413608 · Cited by 24

Relationship between hepcidin and GDF15 in anemic patients with type 2 diabetes without overt renal impairment

Hong, J. H., Choi, Y., Min, B.-K., Park, K. S., Seong, K., Lee, I. K., & Kim, J. G. (2015) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2015.05.001 · Cited by 24

High serum concentrations of growth differentiation factor-15 and their association with Crohn’s disease and a low skeletal muscle index

Yamamoto, H., Takeshima, F., Haraguchi, M., Akazawa, Y., Matsushima, K., Kitayama, M., Ogihara, K., Tabuchi, M., Hashiguchi, K., Yamaguchi, N., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-10587-0 · Cited by 26

Leptin treatment has vasculo-protective effects in lipodystrophic mice

Stürzebecher, P. E., Kralisch, S., Schubert, M. R., Filipova, V., Hoffmann, A., de Oliveira, F. S., Sheikh, B. N., Blüher, M., Kögel, A., Scholz, M. R., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2110374119 · Cited by 24

An inverse relationship between serum macrophage inhibitory cytokine-1 levels and brain white matter integrity in community-dwelling older individuals

Jiang, J., Trollor, J. N., Brown, D. A., Crawford, J. D., Thalamuthu, A., Smith, E., Breit, S. N., Liu, T., Brodaty, H., Baune, B. T., et al. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.07.610 · Cited by 23

Growth differentiation factor 15 as a predictor of adverse renal outcomes in patients with immunoglobulin A nephropathy

Na, K. R., Kim, Y. H., Chung, H. K., Yeo, M., Ham, Y. R., Jeong, J. Y., Kim, K. S., Lee, K. W., & Choi, D. E. (2017) · Internal Medicine Journal · doi:10.1111/imj.13614 · Cited by 23

Growth differentiation factor‐15 for prediction of bleeding in cancer patients

Mulder, F. I., Bosch, F. T. M., Carrier, M., Mallick, R., Middeldorp, S., van Es, N., Kamphuisen, P. W., & Wells, P. S. (2021) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.15559 · Cited by 22

Weight Loss Correlates with Macrophage Inhibitory Cytokine-1 Expression and Might Influence Outcome in Patients with Advanced Esophageal Squamous Cell Carcinoma

Lu, Z., Li, Y., Yu, J., Lü, M., Li, J., Zhou, J., Wang, X., Gong, J., Gao, J., Zhang, X., et al. (2014) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2014.15.15.6047 · Cited by 23

The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid

Steinmetz, B., Hackl, H., Slabáková, E., Schwarzinger, I., Smějová, M., Spittler, A., Arbesú, I., Shehata, M. M., Souček, K., & Wieser, R. (2014) · Cell Cycle · doi:10.4161/15384101.2014.946869 · Cited by 22

A GDF15 3′ UTR variant, rs1054564, results in allele-specific translational repression of GDF15 by hsa-miR-1233-3p

Teng, M., Hsu, L., Juan, S., Lin, W.-C., Lee, M. C., Su, C.-W., Wu, S., & Ko, Y. (2017) · PLoS ONE · doi:10.1371/journal.pone.0183187 · Cited by 21

First Behavioural Characterisation of a Knockout Mouse Model for the Transforming Growth Factor (TGF)-β Superfamily Cytokine, MIC-1/GDF15

Low, J. K., Ambikairajah, A., Shang, K., Brown, D. A., Tsai, V. W.-W., Breit, S. N., & Karl, T. (2017) · PLoS ONE · doi:10.1371/journal.pone.0168416 · Cited by 20

The association between serum levels of growth differentiation factor‐15 and rheumatoid arthritis activity

Esalatmanesh, K., Fayyazi, H., Esalatmanesh, R., & Khabbazi, A. (2020) · International Journal of Clinical Practice · doi:10.1111/ijcp.13564 · Cited by 20

Elevated growth differentiation factor 15 expression predicts poor prognosis in epithelial ovarian cancer patients

Zhang, Y., Hua, W., Niu, L.-C., Li, S., Wang, Y., Shang, L., Zhang, C., Li, W., Wang, R., Chen, B., et al. (2016) · Tumor Biology · doi:10.1007/s13277-015-4699-x · Cited by 20

Current advancements in pharmacotherapy for cancer cachexia

da Fonseca, G. W. P., Sato, R., Alves, M. J. D. N. N., & von Haehling, S. (2023) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2023.2194489 · Cited by 21

Growth Differentiation Factor-15 Produces Analgesia by Inhibiting Tetrodotoxin-Resistant Nav1.8 Sodium Channel Activity in Rat Primary Sensory Neurons

Lin, W., Zhang, W., Lyu, N., Cao, H., Xu, W., & Zhang, Y. (2021) · Neuroscience Bulletin · doi:10.1007/s12264-021-00709-5 · Cited by 20

The Relationship of Serum Macrophage Inhibitory Cytokine – 1 Levels with Gray Matter Volumes in Community-Dwelling Older Individuals

Jiang, J., Wen, W. X., Brown, D. A., Crawford, J., Thalamuthu, A., Smith, E., Breit, S. N., Liu, T., Zhu, W., Brodaty, H., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0123399 · Cited by 20

Use of a proximity extension assay proteomics chip to discover new biomarkers associated with albuminuria

Carlsson, A. C., Sundström, J., Carrero, J. J., Gustafsson, S., Stenemo, M., Larsson, A. O., Lind, L., & Ärnlöv, J. (2016) · European Journal of Preventive Cardiology · doi:10.1177/2047487316676134 · Cited by 19

MIC-1/GDF15 in Barrett’s oesophagus and oesophageal adenocarcinoma

Fisher, O. M., Levert‐Mignon, A., Lord, S. J., Lee-Ng, K. K. M., Botelho, N. K., Falkenback, D., Thomas, M. L., Bobryshev, Y. V., Whiteman, D. C., Brown, D. A., et al. (2015) · British Journal of Cancer · doi:10.1038/bjc.2015.100 · Cited by 19

Value of Growth/Differentiation Factor 15 in Diagnosis and the Evaluation of Chemotherapeutic Response in Lung Cancer

Deng, J., Zhang, M., Zhang, H., Lu, C., Hou, G., Feng, Y., Fang, Z., & Lv, X. (2021) · Clinical Therapeutics · doi:10.1016/j.clinthera.2021.02.001 · Cited by 18

Spirulina platensis supplementation, macrophage inhibitory cytokine-1 (MIC-1), oxidative stress markers and anthropometric features in obese individuals: A randomized controlled trial

Shariat, A., Farhangi, M. A., & Zeinalian, R. (2019) · Journal of Herbal Medicine · doi:10.1016/j.hermed.2019.100264 · Cited by 19

Conserved function of zebrafish (Danio rerio) Gdf15 as a sepsis tolerance mediator

Pereiro, P., Librán-Pérez, M., Figueras, A. J., & Novoa, B. (2020) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2020.103698 · Cited by 16

Growth Differentiation Factor 15 in Severe Aortic Valve Stenosis: Relationship with Left Ventricular Remodeling and Frailty

Fabiani, I., Santoni, T., Angelillis, M., Petricciuolo, S., Colli, A., Pellegrini, G., Mazzei, D., Pugliese, N. R., Petronio, A. S., & Caterina, R. D. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9092998 · Cited by 17

Maternal levels of growth differentiation factor-15 in patients with preeclampsia

Yüksel, İ. T., Mathyk, B. A., Çetin, B. A., Turhan, U., Okumuş, Z. G., Yıldırım, G. Y., & Açar, D. (2018) · Hypertension in Pregnancy · doi:10.1080/10641955.2018.1524477 · Cited by 16

MIC-1/GDF15 Overexpression Is Associated with Increased Functional Recovery in Traumatic Spinal Cord Injury

Golakani, M. H., Mohammad, M. G., Li, H., Gamble, J., Breit, S. N., Ruitenberg, M. J., & Brown, D. A. (2019) · Journal of Neurotrauma · doi:10.1089/neu.2019.6421 · Cited by 15

Macrophage inhibitory cytokine‐1/growth differentiation factor‐15 as a predictor of colonic neoplasia

Danta, M., Barber, D. A., Zhang, H. P., Lee-Ng, M., Baumgart, S., Tsai, V. W.-W., Husaini, Y., Saxena, M., Marquis, C. P., Errington, W., et al. (2017) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.14156 · Cited by 16

Association between MIC-1 and Type 2 Diabetes: A Combined Analysis

Lu, J., Zhang, Y., Dong, X., Lu, J., Zhang, C., Liu, J., Qingzhou, Y., Teng, H., Yao, Q., Yin, J., et al. (2019) · Disease Markers · doi:10.1155/2019/7284691 · Cited by 16

Application of Spirulina as an innovative ingredient in pasta and bakery products

Nejatian, M., Yazdi, A. P. G., Saberian, H., Bazsefidpar, N., Karimi, A., Soltani, A., Assadpour, E., Toker, Ö. S., & Jafari, S. M. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105170 · Cited by 17

Inflammation-associated regulation of the macrophage inhibitory cytokine (MIC-1) gene in prostate cancer

Dubey, S., VanVeldhuizen, P. J., Holzbeierlein, J. M., Tawfik, O. W., Thrasher, J. B., & Karan, D. (2012) · Oncology Letters · doi:10.3892/ol.2012.635 · Cited by 15

Serum GDF ‐15 level in Behçet's disease: relationships between disease activity and clinical parameters

Sarıyıldız, M. A., Yazmalar, L., Batmaz, İ., Alpaycı, M., Burkan, Y. K., Sula, B., Kaplan, İ., Yıldız, M., Akar, Z. A., & Bozkurt, M. (2016) · International Journal of Dermatology · doi:10.1111/ijd.13309 · Cited by 15

Plasma GDF15 level is elevated in psychosis and inversely correlated with severity

Kumar, P., Millischer, V., Villaescusa, J. C., Nilsson, I. A. K., Östenson, C., Schalling, M., Ösby, U., & Lavebratt, C. (2017) · Scientific Reports · doi:10.1038/s41598-017-07503-2 · Cited by 16

NSAID-activated gene 1 mediates pro-inflammatory signaling activation and paclitaxel chemoresistance in type I human epithelial ovarian cancer stem-like cells

Kim, K., Park, S., Do, K. H., Kim, J., Choi, K. U., & Moon, Y. (2016) · Oncotarget · doi:10.18632/oncotarget.12355 · Cited by 16

Growth Differentiation Factor-15 as a Predictor of Idiopathic Membranous Nephropathy Progression: A Retrospective Study

Ham, Y. R., Song, C. H., Bae, H. J., Jeong, J. Y., Yeo, M., Choi, D. E., Na, K. R., & Lee, K. W. (2018) · Disease Markers · doi:10.1155/2018/1463940 · Cited by 15

Association of serum growth differentiation factor 15 level with acute ischemic stroke in a Chinese population

Dong, X., & Nao, J. (2019) · International Journal of Neuroscience · doi:10.1080/00207454.2019.1660327 · Cited by 15

Association of growth differentiation factor 15 (GDF15) polymorphisms with serum GDF15 and ferritin levels in β-thalassemia

Aaron, R., George, B., Mathews, V., Srivastava, A., & Edison, E. S. (2014) · Annals of Hematology · doi:10.1007/s00277-014-2113-1 · Cited by 15

GDF15‐mediated upregulation of ferroportin plays a key role in the development of hyperferritinemia in children with hemophagocytic lymphohistiocytosis

Wu, J., Yuan, L., Ma, Z., Chen, X., Gu, L., & Gao, J. (2013) · Pediatric Blood & Cancer · doi:10.1002/pbc.24373 · Cited by 15

Targeting Stress Erythropoiesis Pathways in Cancer

Vignjević, S., Jauković, A., Milošević, M. S., Bugarski, D. S., & Budeč, M. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.844042 · Cited by 16

Association between growth differentiation factor 15 levels and gestational diabetes mellitus: A combined analysis

Lu, Y., Liu, S.-L., Zhang, Y., Liang, F., Zhu, X., Xiao, Y., Wang, J., Ding, C., Banerjee, S., Yin, J., et al. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1084896 · Cited by 14

Association of circulating growth differentiation factor-15, Krüppel-like factor 4 and growth arrest-specific 6 with coronary artery disease

Liu, H., Lyu, Y., Li, D., Cui, Y., Dai, W., & Li, Y. (2019) · Clinica Chimica Acta · doi:10.1016/j.cca.2019.05.029 · Cited by 14

Erratum to: Elevated growth differentiation factor 15 expression predicts poor prognosis in epithelial ovarian cancer patients

Zhang, Y., Hua, W., Niu, L.-C., Li, S., Wang, Y., Shang, L., Zhang, C., Li, W., Wang, R., Chen, B., et al. (2016) · Tumor Biology · doi:10.1007/s13277-016-5008-z · Cited by 14

Elevated Levels of Growth/Differentiation Factor-15 in the Aqueous Humor and Serum of Glaucoma Patients

Maddala, R., Ho, L. T. Y., Karnam, S., Navarro, I., Osterwald, A., Stinnett, S. S., Ullmer, C., Vann, R. R., Challa, P., & Rao, P. V. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11030744 · Cited by 13

Growth differentiation factor-15 serum concentrations reflect disease severity and anemia in patients with inflammatory bowel disease

Tonkić, A., Kumrić, M., Olic, I. A., Rušić, D., Živković, P. M., Šupe‐Domić, D., Šundov, Ž., Maleš, I., & Božić, J. (2024) · World Journal of Gastroenterology · doi:10.3748/wjg.v30.i13.1899 · Cited by 13

Macrophage inhibitory cytokine‐1 promotes angiogenesis by eliciting the GFRAL‐mediated endothelial cell signaling

Lee, J., Jin, Y., Lee, M., Kim, Y., & Lee, H. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.30144 · Cited by 13

Assessing the Associations of Growth Differentiation Factor 15 with Rheumatic Diseases Using Genetic Data

Ye, D., Liu, B., He, Z., Huang, L. C., Qian, Y., Shao, K., Wen, C., & Mao, Y. (2021) · Clinical Epidemiology · doi:10.2147/clep.s305024 · Cited by 15

The Plasma Proteome Fingerprint Associated with Circulating Carotenoids and Retinol in Older Adults

Yamaguchi, Y., Zampino, M., Tanaka, T., Bandinelli, S., Moaddel, R., Fantoni, G., Candia, J., Ferrucci, L., & Semba, R. D. (2021) · Journal of Nutrition · doi:10.1093/jn/nxab340 · Cited by 14

A Rising Star of the Multimarker Panel: Growth Differentiation Factor-15 Levels Are an Independent Predictor of Mortality in Acute Heart Failure Patients Admitted to an Emergency Clinical Hospital from Eastern Europe

Miftode, R.-Ş., Constantinescu, D., Cianga, C. M., Petriş, A. O., Costache, I. I., Mitu, O., Miftode, I.-L., Mitu, I., Țimpău, A. S., Duca, Ș.-T., et al. (2022) · Life · doi:10.3390/life12121948 · Cited by 13

A novel serum based biomarker panel has complementary ability to preclude presence of early lung cancer for low dose CT (LDCT)

Wang, X., Zhi, X., Yang, Z., Tian, H.-M., Li, Y., Li, M., Zhao, W., Zhang, C., Wang, T., Liu, J., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.17477 · Cited by 13

Mutant GDF15 presents a poor prognostic outcome for patients with oral squamous cell carcinoma

Ma, J., Tang, X., Sun, W., Liu, Y., Tan, Y., Ma, H., Zhu, D., Wang, M., Wang, L., Li, J., et al. (2015) · Oncotarget · doi:10.18632/oncotarget.6017 · Cited by 12

Elevated growth differentiating factor 15 expression predicts long‑term benefit of docetaxel, cisplatin and 5‑fluorouracil induction chemotherapy in patients with oral cancer

Tang, X., Hu, Y., Ju, W., Fu, Y., Sun, W., Liu, Y., Tan, Y., Wang, L., Jiang, L., Tu, Y., et al. (2018) · Oncology Letters · doi:10.3892/ol.2018.8324 · Cited by 12

Genetic determinants of plasma protein levels in the Estonian population

Kalnapenkis, A., Jõeloo, M., Lepik, K., Kukuškina, V., Kals, M., Alasoo, K., Estonian Biobank Research Team, Metspalu, A., Milani, L., Nelis, M., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-57966-3 · Cited by 11

Novel Dual and Triple Agonists Targeting GLP-1, GIP, Glucagon, and GDF15 for Type 2 Diabetes and Obesity Management

Zhang, J., Sanan, S., Csanalosi, M., Zheng, C., & Pfeiffer, A. F. H. (2025) · Endocrinology · doi:10.1210/endocr/bqaf130 · Cited by 13

Contribution of organokines in the development of NAFLD/NASH associated hepatocellular carcinoma

Vachher, M., Bansal, S., Kumar, B., Yadav, S., Arora, T. K., Wali, N. M., & Burman, A. (2022) · Journal of Cellular Biochemistry · doi:10.1002/jcb.30252 · Cited by 11

Growth Differentiation Factor 15 expression and regulation during erythroid differentiation in non-transfusion dependent thalassemia

Ronzoni, L., Sonzogni, L., Duca, L., Graziadei, G., Cappellini, M. D., & Ferru, E. (2014) · Blood Cells Molecules and Diseases · doi:10.1016/j.bcmd.2014.08.006 · Cited by 11

Bleomycin-Induced Pulmonary Changes on Restaging Computed Tomography Scans in Two Thirds of Testicular Cancer Patients Show No Correlation With Fibrosis Markers

den Hollander, M. W., Westerink, N.-D. L., Lubberts, S., Bongaerts, A. H. H., Wolf, R. F. E., Altena, R., Nuver, J., Oosting, S. F., de Vries, E. G. E., Walenkamp, A., et al. (2016) · The Oncologist · doi:10.1634/theoncologist.2015-0451 · Cited by 11

Altered circulating GDF-15 level predicts sex hormone imbalance in males with major depressive disorder

Li, Y., Mei, T., Sun, T., Xiao, X., & Peng, R. (2023) · BMC Psychiatry · doi:10.1186/s12888-023-04527-z · Cited by 10

Effect of Atorvastatin on Growth Differentiation Factor-15 in Patients with Type 2 Diabetes Mellitus and Dyslipidemia

Kim, J. M., Back, M. K., Yi, H., Joung, K. H., Kim, H. J., & Ku, B. J. (2016) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2016.40.1.70 · Cited by 9

Gdf-15 deficiency does not alter vulnerability of nigrostriatal dopaminergic system in MPTP-intoxicated mice

Machado, V., Gilsbach, R., Das, R., Schober, A., Bogatyreva, L., Hauschke, D., KRIEGLSTEIN, K. G., Unsicker, K., & Spittau, B. (2016) · Cell and Tissue Research · doi:10.1007/s00441-016-2406-x · Cited by 10

Quantitative Proteomics Evaluation of Human Multipotent Stromal Cell for β Cell Regeneration.

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