Visceral adiposity index as a predictor of clinical severity and therapeutic outcome of PCOS
Abstract
Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic disease which often accompany with abnormal fat distribution. Visceral adiposity has association with abnormal lipid metabolic, pro-inflammatory activity, insulin resistance (IR) and hyperandrogenism. Increased visceral adiposity raises the risk of metabolic syndrome, type 2 diabetes and cardiovascular (CV) events, and aggravates ovulatory dysfunction and hyperandrogenism in PCOS women. Visceral adiposity index (VAI), a simple surrogate maker of visceral adipose dysfunction and visceral adiposity, is a predictor of IR, and link hyperinsulinemia, hyperandrogenism and anovulation. This review aims to discuss the visceral adiposity situation in PCOS women, and suggests that VAI may be a useful predictor of clinical severity and therapeutic outcome of PCOS.
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Polycystic ovary syndrome (PCOS) is associated with an increased risk of cardiovascular diseases (CVD).
“Polycystic ovary syndrome (PCOS) is associated with an increased risk of cardiovascular diseases (CVD).”
Cites
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- Authors
- Zheng, S.-H., & Li, X.-L.
- Affiliations
- Shanghai Medical College of Fudan University (CN)
- Corresponding author
- Li, Xue-Lian
- ORCID
- Li, Xue-Lian
- Venue
- Gynecological Endocrinology
- Publisher
- Informa UK Limited
- Published
- 2015-11-20
- Volume
- 32
- Issue
- 3
- Pages
- 177-183
- ISSN
- 0951-3590 (ISSN-L)
- 1473-0766
- OpenAlex
- W1823276895
- Cited by
- 63
- References
- 10
- Citations by year
- 2026: 1 · 2025: 9 · 2024: 6 · 2023: 8 · 2022: 7 · 2021: 8 · 2020: 8 · 2019: 3 · 2018: 4 · 2017: 4 · 2016: 5
- FWCI
- 0.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Gynecological Endocrinology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
- Keywords
- polycystic ovary syndrome, visceral adiposity index, visceral fat, insulin resistance, hyperandrogenism, anovulation, metabolic syndrome, cardiovascular risk, treatment outcome prediction, clinical severity
- MeSH terms
- Cardiovascular Diseases, Female, Humans, Inflammation, Insulin Resistance, Menstruation Disturbances, Polycystic Ovary Syndrome, Severity of Illness Index, Hyperandrogenism, Intra-Abdominal Fat, Non-alcoholic Fatty Liver Disease
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