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Cited by 30Dermatological diseases and infestationsDermatology and Skin DiseasesParasitic Diseases Research and Treatment

Efficacy, acceptability and cost effectiveness of four therapeutic agents for treatment of scabies.

Abdel-Raheem, Talal A., Méabed, Eman M. H., Nasef, Ghada A., Abdel Wahed, Wafaa Y., Rohaim, Rania M. A.·2016·Journal of Dermatological Treatment
DOI 10.3109/09546634.2016.1151855
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Abstract

The aim of this study is to evaluate four drug regimens for treatment of scabies as regard their efficacy, acceptability and cost effectiveness. Two hundred cases with ordinary scabies were randomized into four groups. First group received ivermectin 200 μg/kg body weight single oral dose, repeated after one week. The second received benzyl benzoate 20% cream. The third received permethrin 2.5%-5% lotion, whereas the fourth group received 5-10% sulfur ointment. Topical treatments were applied for five consecutive nights. Patients were followed up for two weeks for cure rate and adverse effects. At the end of the study, permethrin provided a significant efficacy of 88% and acceptability in 100% of cases, but had higher cost to treat one case (20.25 LE). Ivermectin provided efficacy and acceptability rates of 84% and 96%, respectively, and had a cheaper cost (9.5 LE). Benzyl benzoate provided 80% for both rates and was the cheapest drug. Sulfur ointment provided the least rates, and it was the most expensive. Treatment choice will depend on the age, the general condition of cases, patient compliance to topical treatment and his ability to stick to its roles, and the economic condition of the patient.

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Crossref · 10.3109/09546634.2016.1151855

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  • Topical permethrin and oral and topical ivermectin have similar efficacy for cure of scabies.

    “Topical permethrin and oral and topical ivermectin have similar efficacy for cure of scabies (1405–1410).”

    From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [1406]

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Authors
Abdel-Raheem, T. A., Méabed, E. M. H., Nasef, G. A., Abdel Wahed, W. Y., & Rohaim, R. M. A.
Affiliations
  • Department of Dermatology, STDs and Andrology, Faculty of Medicine, Fayoum University, Fayoum, Egypt;
  • Fayoum University (EG)
  • Department of Dermatology, STDs and Andrology, Faculty of Medicine, El-Menia University, El-Menia, Egypt;
  • Department of Community Medicine, Faculty of Medicine, Fayoum University, Fayoum, Egypt;
  • Ministry of Health and Population (EG)
Corresponding author
Méabed, Eman M. H.
ORCID
Méabed, Eman M. H.
Venue
Journal of Dermatological Treatment
Publisher
Informa UK Limited
Published
2016-03-30
Volume
27
Issue
5
Pages
473-479
ISSN
  • 0954-6634 (ISSN-L)
  • 1471-1753
DOI
10.3109/09546634.2016.1151855
OpenAlex
W2331757043
Cited by
30
References
47
Citations by year
2026: 6 · 2025: 3 · 2024: 3 · 2023: 1 · 2022: 4 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 3 · 2017: 1
FWCI
2.16
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Dermatological Treatment (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Dermatological diseases and infestations
  • Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
  • Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
Keywords
scabies, scabies treatment, ivermectin, benzyl benzoate, permethrin, sulfur ointment, treatment efficacy, treatment acceptability, cost-effectiveness, cure rate, adverse effects
MeSH terms
Adult, Benzoates, Cost-Benefit Analysis, Female, Humans, Insecticides, Ivermectin, Male, Middle Aged, Scabies, Sulfur, Patient Satisfaction, Permethrin

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