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Cited by 82Dermatological diseases and infestationsDermatology and Skin DiseasesForensic Entomology and Diptera Studies

Scabies: a neglected global disease.

Open access
Leung, Alexander K.C., Lam, Joseph M., Leong, Kin F.·2020·Current Pediatric Reviews
DOI 10.2174/1573396315666190717114131
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Abstract

BACKGROUND: Scabies is a skin disease caused by an obligate human parasite mite Sarcoptes scabiei var. hominis. Children under the age of two and elderly individuals are at the greatest risk. Knowledge of this condition is important for an early diagnosis to be made and treatment to be initiated. OBJECTIVE: The review aimed to familiarize physicians with the clinical manifestations, diagnosis, evaluation, and management of scabies. METHODS: A search was conducted using Pubmed with the built-in "Clinical Queries" tool. The search term "Scabies" was used. The categories of "epidemiology", "diagnosis", "therapy", "prevention" and "prognosis" had a limited scope for primary clinical studies. Meta-analyses, randomized controlled trials, clinical trials, observational studies, and reviews were included. Only papers published in the English language were included. A descriptive, narrative synthesis was provided of the retrieved articles. RESULTS: Worldwide, scabies affects 200 to 300 million individuals annually. The average prevalence is estimated to be 5 to 10% in children of developing countries. Transmission usually occurs after close prolonged skin-to-skin contact. Classic scabies is characterized by an erythematous papular eruption, serpiginous burrows, and intense pruritus. Sites of predilection include the webs of the fingers, volar wrists, lateral aspects of fingers, extensor surfaces of elbows and knees, waist, navel, abdomen, buttocks, groins, and, genitals. A clinical diagnosis of classic scabies can be made on the basis of the history and clinical findings. Other clinical variants include crusted scabies, nodular scabies, and bullous scabies. Finding the mite, ova, or fecal pellets on microscopic examination of scrapings taken from skin lesions confirms the diagnosis of scabies infestation. For eradication of scabies mites, the drugs of choice are topical permethrin and oral ivermectin. CONCLUSION: Scabies is a highly contagious parasitic cutaneous disease that is stigmatising and debilitating. Increased awareness, accurate diagnosis, and prompt treatment are essential for the effective control of scabies and for the prevention of the spread of the disease.

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Crossref · 10.2174/1573396315666190717114131

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  • Scabies among adults frequently is sexually acquired, although scabies among children usually is not.

    “Scabies among adults frequently is sexually acquired, although scabies among children usually is not (1400–1402).”

    From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [1400]

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Authors
Leung, A. K. C., Lam, J. M., & Leong, K. F.
Affiliations
  • University of Calgary (CA)
  • University of British Columbia (CA)
  • Hospital Kuala Lumpur (MY)
Corresponding author
Leung, Alexander K.C.
ORCID
Venue
Current Pediatric Reviews
Publisher
Bentham Science Publishers Ltd.
Published
2020-04-09
Volume
16
Issue
1
Pages
33-42
ISSN
1573-3963 (ISSN-L)
DOI
10.2174/1573396315666190717114131
OpenAlex
W2964125496
Cited by
82
References
108
Citations by year
2026: 4 · 2025: 7 · 2024: 14 · 2023: 23 · 2022: 18 · 2021: 14 · 2020: 2
FWCI
1.18
Type
journal article
Language
en
Open access
Licence
Locations
  • Current Pediatric Reviews (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Dermatological diseases and infestations
  • Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
  • Life Sciences › Agricultural and Biological Sciences › Insect Science › Forensic Entomology and Diptera Studies
Keywords
scabies, Sarcoptes scabiei var. hominis, crusted scabies, nodular scabies, pruritus, burrows, permethrin, ivermectin, mite diagnosis, scabies transmission, scabies prevention, neglected tropical diseases
MeSH terms
Child, Humans, Scabies, Global Health, Neglected Diseases

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