The Association of Irritable Bowel Syndrome and Somatization Disorder
Abstract
BACKGROUND AND OBJECTIVE: Irritable bowel syndrome (IBS) and somatization disorder (SD) are defined by nonobjective symptoms that overlap considerably. Psychiatric symptoms associated with IBS may originate from SD in IBS patients. Previous studies of IBS have not considered SD separately from IBS. METHODS: This study explored psychiatric symptoms and illness behavior in IBS in relation to SD. A total of 50 outpatients with IBS or ulcerative colitis (UC) were evaluated with the Diagnostic Interview Schedule and Illness Behavior Questionnaire. RESULTS: Definite or probable SD was diagnosed in no UC patients and in 42% of IBS patients (confirmed in 25% and lacking one symptom in another 17%). IBS patients with probable or definite SD, but not those without SD, reported more psychiatric symptoms and abnormal illness behaviors than did UC patients. SD accounted for the association of psychiatric symptoms with IBS. CONCLUSIONS: In this university-based office setting, the association of psychiatric features with IBS appears heterogeneous predicated on whether SD is present. Future studies of functional bowel diseases should distinguish between patients with and without SD to clarify its relationship to these disorders. Clinicians should consider whether patients with functional disorders have SD, a diagnosis that indicates specific clinical management strategies.
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The various functional disorders have important characteristics in common, including epidemiology (female predominance), pathophysiology, diagnosis (symptom-based), the central role of the patient-physician relationship in therapy, and common therapeutic modalities.
“The various functional disorders have important characteristics in common, including epidemiology (female predominance), pathophysiology (inflammation, hypersensitivity, impaired central processing of afferent sensory information, role of serotonin, psychological distress and somatization, and the role of stress and life events), diagnosis (symptom-based), the central role of the patient-physician”
From Irritable Bowel Syndrome and Co-morbid Gastrointestinal and Extra-gastrointestinal Functional Syndromes (2010) · cites this paper as [9]
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- Authors
- Miller, A., North, C., Clouse, R., Wetzel, R., Spitznagel, E., & Alpers, D.
- Affiliations
- Washington University in St. Louis (US)
- Venue
- Annals of Clinical Psychiatry
- Publisher
- SAGE Publications
- Published
- 2001-03-01
- Volume
- 13
- Issue
- 1
- Pages
- 25-30
- ISSN
- 1040-1237 (ISSN-L)
- OpenAlex
- W2158384056
- Cited by
- 98
- References
- 0
- Citations by year
- 2025: 1 · 2023: 2 · 2022: 4 · 2021: 2 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 2 · 2016: 2 · 2015: 2 · 2014: 10 · 2013: 4 · 2012: 8
- FWCI
- 4.44
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Clinical Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Keywords
- irritable bowel syndrome, somatization disorder, psychiatric symptoms, illness behavior, ulcerative colitis, functional bowel disorders, somatic symptoms, psychiatric comorbidity
- MeSH terms
- Adult, Colonic Diseases, Functional, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Prognosis, Psychiatric Status Rating Scales, Severity of Illness Index, Somatoform Disorders, Comorbidity
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