GPI Transamidase and GPI anchored proteins: Oncogenes and biomarkers for cancer

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Gaa1p and Gpi8p Are Components of a Glycosylphosphatidylinositol (GPI) Transamidase That Mediates Attachment of GPI to Proteins

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A novel intellectual disability syndrome caused by GPI anchor deficiency due to homozygous mutations in PIGT

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Prostasin Is a Glycosylphosphatidylinositol-anchored Active Serine Protease

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Human PIG-U and Yeast Cdc91p Are the Fifth Subunit of GPI Transamidase That Attaches GPI-Anchors to Proteins

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Requirements for glycosylphosphatidylinositol attachment are similar but not identical in mammalian cells and parasitic protozoa.

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The Murine Receptor for Urokinase-Type Plasminogen Activator Is Primarily Expressed in Tissues Actively Undergoing Remodeling

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PGAP2 Mutations, Affecting the GPI-Anchor-Synthesis Pathway, Cause Hyperphosphatasia with Mental Retardation Syndrome

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Bridging the GAPs in plant reproduction: a comparison of plant and animal GPI-anchored proteins

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Patterns of Gene Expression Profiles Associated with Colorectal Cancer in Colorectal Mucosa by Using Machine Learning Methods

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Identification of PIGU as the Hub Gene Associated with KRAS Mutation in Colorectal Cancer by Coexpression Analysis

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Dysregulation of Serum Exosomal Lipid Metabolism in Schizophrenia: A Biomarker Perspective

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A Novel Immune‐Related Gene Signature Predicts Prognosis of Lung Adenocarcinoma

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Hallmarks of glycogene expression and glycosylation pathways in squamous and adenocarcinoma cervical cancer

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Elucidating cellular interactome of chikungunya virus identifies host dependency factors

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Functional Analysis of the GPI Transamidase Complex by Screening for Amino Acid Mutations in Each Subunit

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Glycosylphosphatidylinositol anchor biosynthesis pathway-based biomarker identification with machine learning for prognosis and T cell exhaustion status prediction in breast cancer

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A Soluble, Minimalistic Glycosylphosphatidylinositol Transamidase (GPI-T) Retains Transamidation Activity

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Construction of novel hypoxia-related gene model for prognosis and tumor microenvironment in endometrial carcinoma

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Program Overview * Conference Program * Conference Posters * Conference Abstracts

Toledo, K. A. D., Fermino, M. L., del Cistia-Andrade, C., Riul, T. B., Rodrigues, L., Alves, R. R., Menjon Muller, V. D., Russo, R. R., Stowell, S. R., Cummings, R. D., et al. (2014) · Glycobiology · doi:10.1093/glycob/cwu087 · Cited by 9 · see citing works

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Therapeutic and Diagnostic Potential of Folic Acid Receptors and Glycosylphosphatidylinositol (GPI) Transamidase in Prostate Cancer

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Structure and Function of the Glycosylphosphatidylinositol Transamidase, a Transmembrane Complex Catalyzing GPI Anchoring of Proteins

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Stability of the transamidase complex catalyzing GPI anchoring of proteins

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Identification and Validation of an Apoptosis-Related Gene Prognostic Signature for Oral Squamous Cell Carcinoma

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The novel immune-related genes predict the prognosis of patients with hepatocellular carcinoma

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Introducing physical exercise as a potential strategy in liver cancer prevention and development.

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Monocytic Differentiation of Human Acute Myeloid Leukemia Cells: A Proteomic and Phosphoproteomic Comparison of FAB-M4/M5 Patients with and without Nucleophosmin 1 Mutations

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Extracellular putrescine can augment the epithelial-mesenchymal transition of gastric cancer cells by promoting MAL2 expression by elevating H3K27ac in its promoter region

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Molecular Insights into Fungal Glycosylphosphatidylinositol Transamidase Complex

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Investigation of Glycosylphosphatidylinositol (GPI)‐Plasma Membrane Interaction in Live Cells and the Influence of GPI Glycan Structure on the Interaction

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Establishment and validation of a gene mutation-based risk model for predicting prognosis and therapy response in acute myeloid leukemia

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Molecular cargo of small EVs from NSCLC patient BALF and plasma: unveiling their role in airway inflammation and immune regulation in a novel human 3D bronchial model

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LY6D identifies persistent stem-like cells driving pancreatic tumourigenesis

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Network topology-based detection of differential gene regulation and regulatory switches in cell metabolism and signaling

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Mechanisms of Quality Control in GPI-Anchored Proteins: The Central Role of the Lipid Anchor

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Single-cell and spatial transcriptomic landscapes reveal PIGT as a pivotal regulator of immunometabolic remodeling in colorectal cancer liver metastasis

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Biochemical And Structural Characterization Of The Core Subunits Of Gpi Transamidase

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Peer Review #1 of "Hallmarks of glycogene expression and glycosylation pathways in squamous and adenocarcinoma cervical cancer (v0.1)"

(2021) · PeerJ · doi:10.7287/peerj.12081v0.1/reviews/1

Peer Review #2 of "Hallmarks of glycogene expression and glycosylation pathways in squamous and adenocarcinoma cervical cancer (v0.1)"

(2021) · PeerJ · doi:10.7287/peerj.12081v0.1/reviews/2

Peer Review #2 of "Hallmarks of glycogene expression and glycosylation pathways in squamous and adenocarcinoma cervical cancer (v0.2)"

(2021) · PeerJ · doi:10.7287/peerj.12081v0.2/reviews/2

Peer Review #3 of "Hallmarks of glycogene expression and glycosylation pathways in squamous and adenocarcinoma cervical cancer (v0.1)"

(2021) · PeerJ · doi:10.7287/peerj.12081v0.1/reviews/3

Investigation of Intercellular Trafficking of Global Glycosylphosphatidylinositol‐Anchored Proteins Using Cell Metabolic Engineering and Transwell Coculture

Kundu, S., Bennett, Z. T., Guo, J., Gupta, P., & Guo, Z. (2025) · Angewandte Chemie · doi:10.1002/ange.202522420

Profiling the expression pattern of GPI transamidase complex subunits in human cancer

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Elevated levels of glycosylphosphatidylinositol (GPI) anchored proteins in plasma from human cancers detected by C. septicum alpha toxin

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Overexpression of Glycosylphosphatidylinositol (GPI) Transamidase Subunits Phosphatidylinositol Glycan Class T and/or GPI Anchor Attachment 1 Induces Tumorigenesis and Contributes to Invasion in Human Breast Cancer

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Proteomic Identification of Glycosylphosphatidylinositol Anchor-dependent Membrane Proteins Elevated in Breast Carcinoma

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