The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Free Radicals and the Regulation of Mammalian Cell Proliferation
Abstract
The question of whether free radicals or free radical-related species play a role in the modulation of mammalian cell proliferation is examined. Although a positive role for free radicals as specific components of mitogenic pathways is not apparent it is clear that certain free radical-derived species can have a significant modulatory influence on components of major growth signal transduction mechanisms. Free radical-derived species are also involved in the production of prostaglandins which themselves can modulate cell growth. Free radicals themselves appear to have a down regulatory effect on cell proliferation inasmuch as protection from oxidative stress enhances cell proliferation. On the other hand, in certain cases low levels of active oxygen species can enhance cell proliferation.
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Citations
Cites
Effect of antioxidants on primary alloantigen-induced T cell activation and proliferation
Chaudhri, G., Clark, I. A., Hunt, N. H., Cowden, W. B., & Ceredig, R. (1986) · The Journal of Immunology · doi:10.4049/jimmunol.137.8.2646 · Cited by 138
Cited by
Schafer, F. Q., & Buettner, G. R. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00480-4 · Cited by 4,587
Role of oxidative stress in cardiovascular diseases
Dhalla, N. S., Temsah, R. M., & Netticadan, T. (2000) · Journal of Hypertension · doi:10.1097/00004872-200018060-00002 · Cited by 1,467
Mitochondrial mutations may increase oxidative stress: Implications for carcinogenesis and aging?
Bandy, B., & Davison, A. J. (1990) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(90)90152-9 · Cited by 550
A redox cycle within the cell cycle: ring in the old with the new
Menon, S. G., & Goswami, P. C. (2007) · Oncogene · doi:10.1038/sj.onc.1209895 · Cited by 294
Do reactive oxygen species play a role in myeloid leukemias?
Hole, P. S., Darley, R. L., & Tonks, A. (2011) · Blood · doi:10.1182/blood-2011-01-326025 · Cited by 254
Metadata
- Authors
- Burdo, R. H., & Rice-Evans, C.
- Venue
- Free Radical Research Communications
- Publisher
- Informa UK Limited
- Published
- 1989-01
- Volume
- 6
- Issue
- 6
- Pages
- 345-358
- ISSN
- 8755-0199 (ISSN-L)
- OpenAlex
- W2282869852
- Cited by
- 189
- References
- 1
- FWCI
- 2.73
- Type
- journal article
- Language
- en
- Open access
- closed
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- Burdo, R. H., & Rice-Evans, C. (1989). Free Radicals and the Regulation of Mammalian Cell Proliferation. Free Radical Research Communications. https://doi.org/10.3109/10715768909087918
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
