The DOI matches its Crossref record; 144 of the 144 references it cites were found in a registry or an index.
Do reactive oxygen species play a role in myeloid leukemias?
Open accessAbstract
Reactive oxygen species (ROS) are a heterogeneous group of molecules that are generated by mature myeloid cells during innate immune responses, and are also implicated in normal intracellular signaling. Excessive production of ROS (and/or a deficiency in antioxidant pathways) can lead to oxidative stress, a state that has been observed in several hematopoietic malignancies including acute and chronic myeloid leukemias (AML and CML). Currently it is unclear what the cause of oxidative stress might be and whether oxidative stress contributes to the development, progression, or maintenance of these diseases. This article reviews the current evidence suggesting a role for ROS both in normal hematopoiesis and in myeloid leukemogenesis, and discusses the usefulness of therapeutically targeting oxidative stress in myeloid malignancy.
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Cites
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Cited by
Campos-Rodriguez, F., Martinez-Garcia, M. A., Martinez, M., Duran-Cantolla, J., Peña, M. D. L., Masdeu, M. J., Gonzalez, M., Campo, F. D., Gallego, I., Marin, J. M., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201209-1671oc · Cited by 386
Redox regulation of protein kinases
Corcoran, A., & Cotter, T. G. (2013) · The FEBS Journal · doi:10.1111/febs.12224 · Cited by 306
Dual effect of oxidative stress on leukemia cancer induction and treatment
Udensi, U. K., & Tchounwou, P. B. (2014) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-014-0106-5 · Cited by 135
TXNIP maintains the hematopoietic cell pool by switching the function of p53 under oxidative stress
Jung, H., Kim, M. J., Kim, D. O., Kim, W. S., Yoon, S.-J., Park, Y.-J., Yoon, S. R., Kim, T.-D., Suh, H.-W., Yun, S., et al. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.06.002 · Cited by 132
The p53 pathway in hematopoiesis: lessons from mouse models, implications for humans
Pant, V., Quintás-Cardama, A., & Lozano, G. (2012) · Blood · doi:10.1182/blood-2012-05-356014 · Cited by 129
Metadata
- Authors
- Hole, P. S., Darley, R. L., & Tonks, A.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 2011-06-02
- Volume
- 117
- Issue
- 22
- Pages
- 5816-5826
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W1997153836
- Cited by
- 254
- References
- 144
- FWCI
- 13.20
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
