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A Short History of Primary Care Practice-based Research Networks: From Concept to Essential Research Laboratories

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Green, L. A., Hickner, J.·2006·The Journal of the American Board of Family Medicine

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Abstract

Sail forth—steer for the deep waters only, reckless O Soul, exploring, I with thee, and thou with me, for we are bound where mariner has not yet dared to go, and we will risk the ship, ourselves and all. —Walt Whitman This is a story about the evolution of practice-based research networks (

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Hygiene, J. O. P. M. A. (2020) · Europe PMC (PubMed Central) · doi:10.15167/2421-4248/jpmh2019.60.4s3
The everyday ethics of primary care
Thompson, T. (2016) · doi:10.1002/9781394322138.ch6
Recruiting Dental Practices for Research: Insights from a Practice-Based Trial in Germany
Hennrich, P., Fehrer, V., Müller, A. L., Daniels-Stumpf, J., Jepsen, S. V., & Listl, S. (2025) · JDR Clinical & Translational Research · doi:10.1177/23800844251357877
“Especially in the United States and the United Kingdom, it has a history spanning several decades back to the 1960s, with its earliest forms being traceable back to the 1800s (Mold and Peterson 2005; Green and Hickner 2006).”
Enabling real-world community pharmacy research: A realist review of practice-based research networks (PBRNs).
Handyside, L., Cameron, J., & Freeman, C. R. (2025) · Research in Social and Administrative Pharmacy · doi:10.1016/j.sapharm.2025.10.004 · Cited by 1
Additional file 2 of Meaningful coproduction with clinicians: establishing a practice-based research network with physiotherapists in regional Australia
Gleadhill, C., Williams, C. M., Kamper, S. J., Alderman, K. B., Delbridge, A., Mahon, B., Donald, B., Delore, C., Boettcher, C., Renfrew, D., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23240083
Additional file 3 of Meaningful coproduction with clinicians: establishing a practice-based research network with physiotherapists in regional Australia
Gleadhill, C., Williams, C. M., Kamper, S. J., Alderman, K. B., Delbridge, A., Mahon, B., Donald, B., Delore, C., Boettcher, C., Renfrew, D., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23240086
Additional file 1 of Features and development trends of primary care research conducted by practice-based research networks from 1991 to 2023: a scoping review protocol
Wang, Y., Cao, X., Xu, Z., & Fang, H. (2024) · Figshare · doi:10.6084/m9.figshare.26653041
Additional file 1 of Meaningful coproduction with clinicians: establishing a practice-based research network with physiotherapists in regional Australia
Gleadhill, C., Williams, C. M., Kamper, S. J., Alderman, K. B., Delbridge, A., Mahon, B., Donald, B., Delore, C., Boettcher, C., Renfrew, D., et al. (2023) · Figshare · doi:10.6084/m9.figshare.23240080
Missing the Forest for the Details of Routine Outcome Monitoring: A Qualitative Inquiry of Clinicians' Experience With the MFT‐PRN
Johnson, L. N., Wagner, K. N., Anderson, S. R., & Hunt, Q. A. (2026) · Journal of Marital and Family Therapy · doi:10.1111/jmft.70114
Orchestrating the Development of a Sustainable Network IT Solution for a Research Network: Qualitative Participatory Multimethod Design
Ateş, G., Thies, C. J., Schweizer, J., Bozorgmehr, A., & Piller, S. (2026) · JMIR Formative Research · doi:10.2196/82952
“Originating in the late 19th century, PBRNs have evolved into structured research entities that facilitate systematic data collection, conduct observational studies, and support innovation within general practice [2-6].”
A five-stage, AI-assisted approach for general practitioners to formulate practice-based research questions
Wang, Y., Zou, C., Mengruo, G., He, L. K., Lu, X., Gui, X., Xu, Z., Lin, K., Jin, H., Yao, M., et al. (2026) · Chinese general practice journal. · doi:10.1016/j.cgpj.2026.100111
La medicina generale come frontiera della cura
Bronzini, M. (2026) · SALUTE E SOCIETÀ · doi:10.3280/ses2026-003004

Authors: Green, L. A., & Hickner, J.
Affiliations: University of Colorado Health (US)
University of Chicago (US)
Venue: The Journal of the American Board of Family Medicine
Publisher: American Board of Family Medicine (ABFM)
Published: 2006-01-01
Volume: 19
Issue: 1
Pages: 1-10
ISSN: 1557-2625 (ISSN-L)
1558-7118
DOI: 10.3122/jabfm.19.1.1
OpenAlex: W2134927115
Cited by: 187
References: 40
Citations by year: 2026: 6 · 2025: 5 · 2024: 5 · 2023: 10 · 2022: 4 · 2021: 5 · 2020: 10 · 2019: 7 · 2018: 6 · 2017: 5 · 2016: 6 · 2015: 20 · 2014: 16 · 2013: 7 · 2012: 21
FWCI: 22.52
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: The Journal of the American Board of Family Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Family Practice › Primary Care and Health Outcomes
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health and Medical Research Impacts
Health Sciences › Health Professions › General Health Professions › Health Sciences Research and Education
Keywords: practice-based research networks, primary care research, research infrastructure, family medicine research
MeSH terms: Family Practice, Humans, Laboratories, Primary Health Care, Research Support as Topic, United States, Biomedical Research, History, 20th Century

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A Short History of Primary Care Practice-based Research Networks: From Concept to Essential Research Laboratories

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