Antihypertensive Effect of the Peptides Derived from Casein by an Extracellular Proteinase from Lactobacillus helveticus CP790

Spectrophotometric Assay Using o-Phthaldialdehyde for Determination of Proteolysis in Milk and Isolated Milk Proteins

Church, F., Swaisgood, H. E., Porter, D. H., & Catignani, G. L. (1983) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(83)81926-2 · Cited by 1,579

Design of potent competitive inhibitors of angiotensin-converting enzyme. Carboxyalkanoyl and mercaptoalkanoyl amino acids

Cushman, D. W., Cheung, H. S., Sabo, E. F., & Ondetti, M. A. (1977) · Biochemistry · doi:10.1021/bi00644a014 · Cited by 893

Angiotensin I converting enzyme.

Erdös, E. G. (1975) · Circulation Research · doi:10.1161/01.res.36.2.247 · Cited by 555

Angiotensin-converting enzyme inhibitors from the venom of Bothrops jararaca. Isolation, elucidation of structure, and synthesis

Ondetti, M. A., Williams, N. J., Sabo, E. F., PLUSCEC, J., Weaver, E. R., & Kocy, O. (1971) · Biochemistry · doi:10.1021/bi00798a004 · Cited by 521

Isolation of bradykinin-potentiating peptides from Bothrops jararaca venom

Ferreira, S. H., Bartelt, D. C., & Greene, L. J. (1970) · Biochemistry · doi:10.1021/bi00815a005 · Cited by 515

Isolation of bradykinin-potentiating peptides from Bothrops jararaca venom

J.P. (1971) · Toxicon · doi:10.1016/0041-0101(71)90098-5 · Cited by 480

Angiotensin I-Converting Enzyme Inhibitor Derived from an Enzymatic Hydrolysate of Casein. II. Isolation and Bradykinin-potentiating Activity on the Uterus and the Ileum of Rats

Maruyama, S., Nakagomi, K., Tomizuka, N., & Suzuki, H. (1985) · Agricultural and Biological Chemistry · doi:10.1080/00021369.1985.10866901 · Cited by 201

Untitled work

(1981) · Cited by 154

Antihypertensive effect of tryptic hydrolysate of milk casein in spontaneously hypertensive rats

Karaki, H., Kunio, D., SUGANO, S., Hideyo, U., Ryuji, S., Umeji, M., & Takemoto, S. (1990) · Comparative Biochemistry and Physiology Part C Comparative Pharmacology · doi:10.1016/0742-8413(90)90023-3 · Cited by 135

Angiotensin I-converting enzyme inhibitors derived from an enzymatic hydrolysate of casein. Part IV Studies on the active site and antihypertensive activity of angiotensin I-converting enzyme inhibitors derived from casein.

Maruyama, S., Mitachi, H., Tanaka, H., Tomizuka, N., & Suzuki, H. (1987) · Agricultural and Biological Chemistry · doi:10.1271/bbb1961.51.1581 · Cited by 126

Antihypertensive Peptides Specific to Lactobacillus helveticus Fermented Milk

Wakai, T., & Yamamoto, N. (2012) · Biotechnology - Molecular Studies and Novel Applications for Improved Quality of Human Life · doi:10.5772/28695 · Cited by 36

Invited review: Camel milk–derived bioactive peptides and diabetes—Molecular view and perspectives

Ayoub, M. A., Yap, P., Mudgil, P., Khan, F. B., Anwar, I., Muhammad, K., Gan, C., & Maqsood, S. (2023) · Journal of Dairy Science · doi:10.3168/jds.2023-23733 · Cited by 33

Identification of an antihypertensive peptide derived from chicken bone extract

Nakade, K., 上島, 良., Inoue, Y., Ahhmed, A. M., Kawahara, S., Nakayama, T., Maruyama, M., NUMATA, M., Ohta, K., Aoki, T., et al. (2008) · Animal Science Journal · doi:10.1111/j.1740-0929.2008.00584.x · Cited by 33

Antihypertensive effect of the milk fermented by culturing with various lactic acid bacteria and a yeast

Kuwabara, Y., Nagai, S., Yoshimitsu, N., Nakagawa, I., Watanabe, Y., & Tamai, Y. (1995) · Journal of Fermentation and Bioengineering · doi:10.1016/0922-338x(95)90834-m · Cited by 33

Implication of Gut Microbiota in Human Health

Khan, I., Yasir, M., Azhar, E. I., Kumosani, T. A., Barbour, E. K., Bibi, F., & Kamal, M. A. (2014) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527313666141023153506 · Cited by 35

Purification and identification of an angiotensin I-converting enzyme inhibitory peptide from cauliflower by-products protein hydrolysate

Xu, Y., Bao, T., Han, W., Chen, W., Zheng, X., & Wang, J. (2016) · Process Biochemistry · doi:10.1016/j.procbio.2016.05.023 · Cited by 33

Antioxidant and angiotensin-converting enzyme (ACE) inhibitory activity of thymosin alpha-1 (Thα1) peptide

Khorassani, J. K., Asoodeh, A., & Tanzadehpanah, H. (2019) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2019.04.003 · Cited by 33

Lactic Fermentation and Bioactive Peptides

Pihlanto, A. (2013) · InTech eBooks · doi:10.5772/51692 · Cited by 33

Does fermented milk possess antihypertensive effect in humans?

Usinger, L., Ibsen, H., & Jensen, L. T. (2009) · Journal of Hypertension · doi:10.1097/hjh.0b013e3283292716 · Cited by 32

The addition of probiotic promotes the release of ACE-I peptide of Cheddar cheese: Peptide profile and molecular docking

Hao, X., Yu, X., Wang, Y., Zhang, X., & Liu, L. (2022) · International Dairy Journal · doi:10.1016/j.idairyj.2022.105507 · Cited by 32

Casein Hydrolysates by Lactobacillus brevis and Lactococcus lactis Proteases: Peptide Profile Discriminates Strain-Dependent Enzyme Specificity

Bounouala, F. Z., Roudj, S., Karam, N.-E., Recio, I., & Miralles, B. (2017) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.7b03203 · Cited by 32

Dairy yeasts produce milk protein-derived antihypertensive hydrolysates

García-Tejedor, A., Padilla, B., Salom, J. B., Belloch, C., & Manzanares, P. (2013) · Food Research International · doi:10.1016/j.foodres.2013.05.005 · Cited by 31

Enzymatic digestion of the milk protein β-casein releases potent chemotactic peptide(s) for monocytes and macrophages

Kitazawa, H., Yonezawa, K., Tohno, M., Shimosato, T., Kawai, Y., Saito, T., & Wang, J. M. (2007) · International Immunopharmacology · doi:10.1016/j.intimp.2007.04.008 · Cited by 31

Hypotensive Effects of The Tablets Containing "Lactotripeptides (VPP, IPP)"

Kajimoto, O., Aihara, K., Hirata, H., Takahashi, R., & Nakamura, Y. (2001) · Cited by 30

Effects of Heat-Treated Lactobacillus helveticus CP790-Fermented Milk on Gastrointestinal Health in Healthy Adults: A Randomized Double-Blind Placebo-Controlled Trial

Tanihiro, R., Yuki, M., Sakano, K., Sasai, M., Sawada, D., Ebihara, S., & Hirota, T. (2024) · Nutrients · doi:10.3390/nu16142191 · Cited by 29

Exploring Potential Bioactive Peptides in Fermented Bactrian Camel’s Milk and Mare’s Milk Made by Mongolian Nomads

Ganzorig, K., Urashima, T., & Fukuda, K. (2020) · Foods · doi:10.3390/foods9121817 · Cited by 29

Exploring the potential of Lactobacillus and Saccharomyces for biofunctionalities and the release of bioactive peptides from whey protein fermentate

Dineshbhai, C. K., Basaiawmoit, B., Sakure, A. A., Maurya, R., Bishnoi, M., Kondepudi, K. K., Patil, G. B., Mankad, M., Liu, Z., & Hati, S. (2022) · Food Bioscience · doi:10.1016/j.fbio.2022.101758 · Cited by 29

Two‐Dimensional1H‐NMR and CD Structural Analysis in a Micellar Medium of a Bovine αs1‐Casein Fragment having Benzodiazepine‐Like Properties

Lecouvey, M., Frochot, C., Miclo, L., Orlewski, P., Driou, A., Linden, G., Gaillard, J., Marraud, M., Cung, M. T., & Vanderesse, R. (1997) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1997.00872.x · Cited by 29

Bioactive Peptides in Yogurt

Mann, B., Athira, S., Sharma, R., & Bajaj, R. K. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805134-4.00024-9 · Cited by 28

Preparation of angiotensin-I-converting enzyme inhibitory hydrolysates from unsupplemented caprine whey fermentation by various cheese microflora

Didelot, S., Bordenave-Juchereau, S., Rosenfeld, E., Fruitier‐Arnaudin, I., Piot, J., & Sannier, F. (2005) · International Dairy Journal · doi:10.1016/j.idairyj.2005.09.009 · Cited by 28

ACE Inhibitory Peptides

Murray, B. A., Walsh, D., Fitzgerald, R. J., & Meisel, H. (2005) · Nutraceutical science and technology · doi:10.1201/9781420028836.sec3 · Cited by 28

Bioactive peptides encrypted in milk proteins: proteolytic activation and thropho-functional properties

Meisel, H., & Bockelmann, W. (1999) · Springer eBooks · doi:10.1007/978-94-017-2027-4_10 · Cited by 29

An Update on the Cardiovascular Pleiotropic Effects of Milk and Milk Products

Chrysant, S. G., & Chrysant, G. S. (2013) · Journal of Clinical Hypertension · doi:10.1111/jch.12110 · Cited by 27

Peptidomic analysis of milk fermented by Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus

Yu, Y., Yu, W., & Jin, Y. (2021) · Food Hydrocolloids for Health · doi:10.1016/j.fhfh.2021.100033 · Cited by 27

Purification and Characterization of Antioxidative Peptides Derived From Fermented Milk (Lassi) by Lactic Cultures

Padghan, P. V., Mann, B., & Hati, S. (2017) · International Journal of Peptide Research and Therapeutics · doi:10.1007/s10989-017-9608-2 · Cited by 29

Profiles, antioxidative and ACE inhibitory activity of peptides released from fermented buttermilk before and after simulated gastrointestinal digestion

Magouz, O., Mehanna, N. M., Khalifa, M., Sakr, H., Gensberger‐Reigl, S., Dalabasmaz, S., & Pischetsrieder, M. (2023) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2022.103266 · Cited by 25

Ultrasound‐assisted generation of ACE‐inhibitory peptides from casein hydrolyzed with nanoencapsulated protease

Madadlou, A., Sheehan, D., Emam‐Djomeh, Z., & Mousavi, M. (2011) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.4438 · Cited by 25

Peptidomics-based identification of antihypertensive and antidiabetic peptides from sheep milk fermented using Limosilactobacillus fermentum KGL4 MTCC 25515 with anti-inflammatory activity: in silico, in vitro, and molecular docking studies

Pipaliya, R., Basaiawmoit, B., Sakure, A. A., Maurya, R., Bishnoi, M., Kondepudi, K. K., Singh, B. P., Paul, S., Liu, Z., Sarkar, P., et al. (2024) · Frontiers in Chemistry · doi:10.3389/fchem.2024.1389846 · Cited by 24

Adjacent-possible ecological niche: growth of Lactobacillus species co-cultured with Escherichia coli in a synthetic minimal medium

Mizuno, K., Mizuno, M., Yamauchi, M., Takemura, A. J., Romero, V. M., & Morikawa, K. (2017) · Scientific Reports · doi:10.1038/s41598-017-12894-3 · Cited by 24

Production of active angiotensin‐I converting enzyme inhibitory peptides derived from bovine β‐casein by recombinant DNA technologies

Losacco, M., Gallerani, R., Gobbetti, M., Minervini, F., & Leo, F. D. (2007) · Biotechnology Journal · doi:10.1002/biot.200700092 · Cited by 24

Peptides from Cauliflower By-Products, Obtained by an Efficient, Ecosustainable, and Semi-Industrial Method, Exert Protective Effects on Endothelial Function

Caliceti, C., Capriotti, A. L., Calabria, D., Bonvicini, F., Chiozzi, R. Z., Montone, C. M., Piovesana, S., Zangheri, M., Mirasoli, M., Simoni, P., et al. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/1046504 · Cited by 25

Purification and Molecular Characterization of a Tripeptidase (PepT) from Lactobacillus helveticus

Savijoki, K., & Palva, A. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.2.794-800.2000 · Cited by 24

Editing of the Proteolytic System of Lactococcus lactis Increases Its Bioactive Potential

Huang, C., & Kok, J. (2020) · Applied and Environmental Microbiology · doi:10.1128/aem.01319-20 · Cited by 23

Proteomics Analysis in Dairy Products: Cheese, a Review

Bouroutzika, E. V., Proikakis, S., Anagnostopoulos, A. K., Katsafadou, A. I., Fthenakis, G. C., & Tsangaris, G. T. (2021) · Applied Sciences · doi:10.3390/app11167622 · Cited by 23

LC-Q-TOF/MS based identification and in silico verification of ACE-inhibitory peptides in Giresun (Turkey) hazelnut cakes

Çağlar, A. F., Çakır, B., & Gülseren, İ. (2021) · European Food Research and Technology · doi:10.1007/s00217-021-03700-6 · Cited by 22

Characterization of the Norwegian autochthonous cheese Gamalost and its angiotensin I-converting enzyme (ACE) inhibitory activity during ripening

Qureshi, T. M., Vegarud, G. E., Abrahamsen, R. K., & Skeie, S. B. (2012) · Dairy Science and Technology · doi:10.1007/s13594-012-0078-1 · Cited by 23

Studies of the Toxicological Potential of Tripeptides (L-Valyl-L-prolyl-L-proline and L-lsoleucyl-L-prolyl-L-proline): II. Introduction

Bernard, B. K., Nakamura, Y., Bando, I., & Mennear, J. H. (2005) · International Journal of Toxicology · doi:10.1080/10915810500259531 · Cited by 22

Péptidos bioactivos

Mulero, J., Zafrilla, P., Martínez, A. M.-C., Hernández, M. L., & Alemán, J. A. (2011) · Clínica e Investigación en Arteriosclerosis · doi:10.1016/j.arteri.2011.04.004 · Cited by 22

Production of Angiotensin-I-Converting-Enzyme-Inhibitory Peptides in Fermented Milks (Lassi) Fermented by Lactobacillus acidophillus with Consideration of Incubation Period and Simmering Treatment

Padghan, P. V., Mann, B., Sharma, R., Bajaj, R. K., & Saini, P. (2016) · International Journal of Peptide Research and Therapeutics · doi:10.1007/s10989-016-9540-x · Cited by 21

Biochemistry of fermentation

Tamime, A. Y., & Robinson, R. K. (2007) · Elsevier eBooks · doi:10.1533/9781845692612.535 · Cited by 21

Purification and identification of an ACE-inhibitory peptide from walnut protein hydrolysate

Wang, C., Song, W., Lianzhou, J., & Du, M. (2014) · European Food Research and Technology · doi:10.1007/s00217-014-2227-7 · Cited by 21

Anti-Hypertensive Peptides Derived from Caseins: Mechanism of Physiological Action, Production Bioprocesses, and Challenges for Food Applications

de Oliveira, M. R., Silva, T. J., Barros, E., Guimarães, V. M., Baracat‐Pereira, M. C., Eller, M. R., Coimbra, J. S. D. R., & de Oliveira, E. B. (2018) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-018-2692-8 · Cited by 19

Casein and Whey Proteins in Human Health

Petrotos, K., Tsakali, E., Goulas, P., & D‘Alessandro, A. G. (2014) · Wiley eBooks · doi:10.1002/9781118635056.ch4 · Cited by 19

Lactobacillus helveticus-Fermented Milk Whey Suppresses Melanin Production by Inhibiting Tyrosinase through Decreasing MITF Expression

Ikarashi, N., Fukuda, N., Ochiai, M., Sasaki, M., Kon, R., Sakai, H., Hatanaka, M., & Kamei, J. (2020) · Nutrients · doi:10.3390/nu12072082 · Cited by 18

Engineering production of antihypertensive peptides in plants

Rosales‐Mendoza, S., Paz-Maldonado, L. M. T., Govea‐Alonso, D. O., & Korban, S. S. (2012) · Plant Cell Tissue and Organ Culture (PCTOC) · doi:10.1007/s11240-012-0231-9 · Cited by 18

Differential effects of sheep and cow skim milk before and after fermentation on gastrointestinal transit of solids in a rat model

Dalziel, J. E., Smolenski, G., McKenzie, C. M., Haines, S. R., & Day, L. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.05.039 · Cited by 18

Soluble Lactobacillus delbrueckii subsp. bulgaricus 92059 PrtB proteinase derivatives for production of bioactive peptide hydrolysates from casein

Li, B., Habermann, D., Kliche, T., Klempt, M., Wutkowski, A., Clawin‐Rädecker, I., Koberg, S., Brinks, E., Koudelka, T., Tholey, A., et al. (2019) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-018-09586-x · Cited by 19

Exploring Potential Therapeutic Properties of Camel Milk

Alhaj, O. A. (2019) · Practice, progress, and proficiency in sustainability · doi:10.4018/978-1-7998-1604-1.ch007 · Cited by 18

Classification of Lactobacillus helveticus Strains by Immunological Differences in Extracellular Proteinases

YAMAMOTO, N., ONO, H., MAENO, M., UEDA, Y., TAKANO, T., & MOMOSE, H. (1998) · Bioscience, Biotechnology, and Biochemistry · doi:10.1271/bbb.62.1228 · Cited by 17

Lactobacillus group and arterial hypertension: A broad review on effects and proposed mechanisms

Gadelha, D. D. A., Alves, J. L. D. B., da Costa, P. C. T., da Luz, M. S., Cavalcanti, C. D. O., Bezerril, F. F., Almeida, J. F., Cruz, J. C., Magnani, M., Balarini, C. M., et al. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2136618 · Cited by 17

Peptidomic analysis of the angiotensin-converting-enzyme inhibitory peptides in milk fermented with Lactobacillus delbrueckii QS306 after ultrahigh pressure treatment

Wu, N., Zhang, F., & Shuang, Q. (2022) · Food Research International · doi:10.1016/j.foodres.2022.112406 · Cited by 16

Addition of Anionic Polysaccharide Stabilizers Modulates In Vitro Digestive Proteolysis of a Chocolate Milk Drink in Adults and Children

David, S., Klaiman, M. M., Shpigelman, A., & Lesmes, U. (2020) · Foods · doi:10.3390/foods9091253 · Cited by 16

Milk-clotting and hydrolytic activities of an aspartic protease from Salpichroa origanifolia fruits on individual caseins

Rocha, G. F., Cotabarren, J., Obregón, W. D., Fernández, G., Rosso, A. M., & Parisi, M. G. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.10.004 · Cited by 16

Milk protein-based cryogel monoliths as novel encapsulants of probiotic bacteria. Part II: Lacticaseibacillus rhamnosus GG storage stability and bioactivity under in vitro digestion

Hellebois, T., Canuel, R., Leclercq, C. C., Gaïani, C., & Soukoulis, C. (2023) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2023.109173 · Cited by 16

Effect of Allium sativum and Fish Collagen on the Proteolytic and Angiotensin-I Converting Enzyme-inhibitory Activities in Cheese and Yogurt

Shori, A. B., Baba, A. S., & Keow, J. N. (2012) · Pakistan Journal of Biological Sciences · doi:10.3923/pjbs.2012.1160.1167 · Cited by 16

ACE-inhibitory Effect and Physicochemical Characteristics of Yogurt Beverage Fortified with Whey Protein Hydrolysates

Lim, S.-M., Lee, N., Park, K. K., Yoon, Y. C., & Paik, H. (2011) · Korean Journal for Food Science of Animal Resources · doi:10.5851/kosfa.2011.31.6.886 · Cited by 17

Proteome analysis of Lactobacillus helveticus H9 during growth in skim milk

Chen, Y. F., Zhao, W., Wu, R., Sun, Z., Zhang, W. Y., Wang, J. C., Bilige, M., & Zhang, H. P. (2014) · Journal of Dairy Science · doi:10.3168/jds.2014-8520 · Cited by 16

Bioactive Peptides from Fermented Foods: Their Role in the Immune System

Matar, C., Goulet, J., Bernier, R. L., & Brochu, E. (2000) · Springer eBooks · doi:10.1007/978-94-017-2768-6_8 · Cited by 16

An Integrated Comprehensive Peptidomics and In Silico Analysis of Bioactive Peptide-Rich Milk Fermented by Three Autochthonous Cocci Strains

Banić, M., Butorac, K., Čuljak, N., Butorac, A., Novak, J., Pavunc, A. L., Rušanac, A., Stanečić, Ž., Lovrić, M., Šušković, J., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25042431 · Cited by 15

A milk casein hydrolysate‐derived peptide enhances glucose uptake through the AMP‐activated protein kinase signalling pathway in skeletal muscle cells

Iwasa, M., Takezoe, S., Kitaura, N., Sutani, T., Miyazaki, H., & Aoi, W. (2020) · Experimental Physiology · doi:10.1113/ep088770 · Cited by 15

Industrial Utilization of Bioactive Hazelnut Peptide Fractions in the Manufacture of Functional Hazelnut Paste: ACE-Inhibition and Allergy Suppression

Göksu, A. G., Çakır, B., & Gülseren, İ. (2022) · Waste and Biomass Valorization · doi:10.1007/s12649-022-01750-9 · Cited by 15

In situ generation of milk protein-derived peptides in drying-off cows

Ho, C. H., Chang, C. J., Liu, W. B., Peh, H. C., Chen, S., Chen, H. Y., Ho, T.-H., Chen, M. T., & Nagahata, H. (2010) · Journal of Dairy Research · doi:10.1017/s0022029910000634 · Cited by 15

Effect of Casein Hydrolysates on Intestinal Cell Migration and Their Peptide Profiles by LC-ESI/MS/MS

Nielsen, S. D.-H., Purup, S., & Larsen, L. B. (2019) · Foods · doi:10.3390/foods8030091 · Cited by 15

Improvement of functional and sensory properties of fermented dairy drink Narine using raw apricot gum

Hovhannisyan, H., Danielyan, L., Chichoyan, N., Pashayan, M. M., Baghdasaryan, L. G., Melkumyan, I., & Barseghyan, A. (2024) · Functional Foods in Health and Disease · doi:10.31989/ffhd.v14i8.1398 · Cited by 14

Effects of camel milk hydrolysate on blood pressure and biochemical parameters in fructose-induced hypertensive rats

Alshuniaber, M. A., Alhaj, O. A., Abdallah, Q., & Jahrami, H. (2021) · Nutrition & Food Science · doi:10.1108/nfs-04-2021-0130 · Cited by 14

Comparative analysis of proteolytic enzymes need for processing of antihypertensive peptides between Lactobacillus helveticus CM4 and DPC4571

Wakai, T., Shinoda, T., Uchida, N., Hattori, M., Nakamura, Y., Beresford, T. P. J., Ross, R. P., & Yamamoto, N. (2012) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2012.09.020 · Cited by 14

Effects of a Casein Hydrolysate Prepared fromAspergillus oryzaeProtease on Adjuvant Arthritis in Rats

HATORI, M., Ohki, K., Hirano, S., Yang, X., Kuboki, H., & Abe, C. (2008) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.70792 · Cited by 14

Proteolytic and angiotensin‐converting enzyme‐inhibitory activities of selected probiotic bacteria

Ahtesh, F. B., Stojanovska, L., Mathai, M. L., Apostolopoulos, V., & Mishra, V. K. (2016) · International Journal of Food Science & Technology · doi:10.1111/ijfs.13054 · Cited by 14

Studies on Anti-Hypertensive Peptides in Milk Fermented with Lactobacillus helveticus

Nakamura, Y. (2004) · Bioscience and Microflora · doi:10.12938/bifidus.23.131 · Cited by 14

Mushroom Sparassis crispa (Hanabiratake) Fermented with Lactic Acid Bacteria Significantly Enhances Innate Immunity of Mice

Nishioka, J., Hiramoto, K., & Suzuki, K. (2020) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b19-00724 · Cited by 13

Purification and Characterization of Novel Antihypertensive and Antioxidative Peptides From Whey Protein Fermentate: In Vitro, In Silico, and Molecular Interactions Studies

Chopada, K., Basaiawmoit, B., Sakure, A. A., Maurya, R., Bishnoi, M., Kondepudi, K. K., Solanki, D. K., Singh, B. P., Padhi, S., Rai, A. K., et al. (2022) · Journal of the American Nutrition Association · doi:10.1080/27697061.2022.2110966 · Cited by 13

Coupled Neutrase–Catalyzed Plastein Reaction Mediated the ACE-Inhibitory ActivityIn Vitroof Casein Hydrolysates Prepared by Alcalase

Xu, W., Li, T., & Zhao, X. (2012) · International Journal of Food Properties · doi:10.1080/10942912.2011.553759 · Cited by 13

Protein hydrolysate batch production with angiotensin I-converting enzyme inhibitory activity form egg whites

Chiang, W., Lee, M.-J., Guo, W., & Tsai, T. C. (2020) · Journal of Food and Drug Analysis · doi:10.38212/2224-6614.2453 · Cited by 13

Genetics of Lactic Acid Bacteria

McAuliffe, O. E. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-417012-4.00009-0 · Cited by 13

Milk‐derived Bioactive Components from Fermentation

Alhaj, O. A., & Kanekanian, A. D. (2014) · Wiley eBooks · doi:10.1002/9781118635056.ch8 · Cited by 14

Determination of extracellular proteinase in L. helveticus Lh191404 based on whole genome sequencing and proteomics analysis

Liu, Q., Wang, H., Zhu, W., Peng, S., Zou, H., Zhang, P., Li, Z., Zhang, Z., Fu, L., & Qian, Z. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.133958 · Cited by 12

The multifunctional activity of water‐soluble peptides’ extract of Domiati cheese during accelerated ripening by Neutrase

Taha, S., Abd, M. E., Gobba, C. D., Abdel-Hamid, M., Khalil, E. M., Hassan, F., & Fathy, D. (2020) · Journal of Food Processing and Preservation · doi:10.1111/jfpp.14434 · Cited by 12

Extraction optimization for combined metabolomics, peptidomics, and proteomics analysis of gut microbiota samples

Keller, C., Wei, P., Wancewicz, B., Cross, T.-W., Rey, F. E., & Li, L. (2020) · Journal of Mass Spectrometry · doi:10.1002/jms.4625 · Cited by 12

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Aires, R., Amorim, F. G., Côco, L. Z., da Conceição, A. P., Zanardo, T. É. C., Taufner, G. H., Nogueira, B. V., Vasquez, E. C., Pereira, T. D. M. C., Campagnaro, B. P., et al. (2022) · Food & Function · doi:10.1039/d1fo01798e · Cited by 12

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Rocha, R. S., de Oliveira, L. B., Morais, S. T. B., Soutelino, M. E. M., Silva, M. C., Freitas, M. Q., Bogusz, S., Pimentel, T. C., Esmerino, E. A., & da Cruz, A. G. (2023) · International Dairy Journal · doi:10.1016/j.idairyj.2023.105733 · Cited by 12

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Lecouvey, M., Frochot, C., Miclo, L., Orlewski, P., Marraud, M., Gaillard, J., Cung, M. T., & Vanderesse, R. (1997) · International Journal of Peptide Research and Therapeutics · doi:10.1007/bf02442900 · Cited by 12

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Yamamoto, N., Akino, A., Takano, T., & Shishido, K. (1995) · Applied and Environmental Microbiology · doi:10.1128/aem.61.2.698-701.1995 · Cited by 11

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Chen, G., Tsai, J., & Pan, B. S. (2007) · Journal of Food Biochemistry · doi:10.1111/j.1745-4514.2007.00135.x · Cited by 10

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Maeno, M., Yamamoto, N., & Takano, T. (1996) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(96)76487-1 · Cited by 392

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