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Cited by 512

The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

Neurosurgical management of low-grade astrocytoma of the cerebral hemispheres

Laws, Edward R., Taylor, William F., Clifton, Marvin B., Okazaki, Haruo·1984·Journal of Neurosurgery

Abstract

✓ The authors conducted a retrospective review of surgically treated, histologically proven cases of low-grade (Grade 1 or 2) astrocytomas. Follow-up analysis, with survival time as the end-point, was completed using multivariant statistical analysis. In the 461 cases of supratentorial low-grade astrocytoma in this study, age of the patient at the time of surgery was by far the most important variable in predicting length of survival. Other variables correlating with increasing survival times were: gross total surgical removal, lack of major preoperative neurological deficit, long duration of symptoms prior to surgery, seizures as a presenting symptom, lack of major postoperative neurological deficit, and surgery performed in recent decades. The multi-variant regression analysis showed that radiation therapy was of clear benefit, primarily in older patients with incompletely removed tumors. For purposes of establishing prognosis and testing the results, a “score” was developed to predict survival times, based on the most important variables. The data in this study provide a basis for the analysis of future modes of management of low-grade gliomas.

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Metadata

Authors
Laws, E. R., Taylor, W. F., Clifton, M. B., & Okazaki, H.
Venue
Journal of Neurosurgery
Published
1984-10
Volume
61
Issue
4
Pages
665-673
ISSN
0022-3085 (ISSN-L)
OpenAlex
W2102628178
Cited by
512
References
12
FWCI
7.33
Type
journal article
Language
en
Open access
closed

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This page
CoChat. (2026). Citation check: Neurosurgical management of low-grade astrocytoma of the cerebral hemispheres. https://app.cochat.ai/papers/10.3171/jns.1984.61.4.0665
The paper
Laws, E. R., Taylor, W. F., Clifton, M. B., & Okazaki, H. (1984). Neurosurgical management of low-grade astrocytoma of the cerebral hemispheres. Journal of Neurosurgery. https://doi.org/10.3171/jns.1984.61.4.0665

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.