The DOI matches its Crossref record; 101 of the 101 references it cites were found in a registry or an index.
Considering sex and gender in Alzheimer disease and other dementias
Open accessAbstract
Suffering related to dementia is multifaceted because cognitive and physical functioning slowly deteriorates. Advanced age and sex, two of the most prominent risk factors for dementia, are not modifiable. Lifestyle factors such as smoking, excessive alcohol use, and poor diet modulate susceptibility to dementia in both males and females. The degree to which the resulting health conditions (eg, obesity, type 2 diabetes, and cardiovascular disease) impact dementia risk varies by sex. Depending on the subtype of dementia, the ratio of male to female prevalence differs. For example, females are at greater risk of developing Alzheimer disease dementia, whereas males are at greater risk of developing vascular dementia. This review examines sex and gender differences in the development of dementia with the goal of highlighting factors that require further investigation. Considering sex as a biological variable in dementia research promises to advance our understanding of the pathophysiology and treatment of these conditions.
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Metadata
- Authors
- Podcasy, J. L., & Epperson, C. N.
- Venue
- Dialogues in Clinical Neuroscience
- Publisher
- Informa UK Limited
- Published
- 2016-12-31
- Volume
- 18
- Issue
- 4
- Pages
- 437-446
- ISSN
- 1294-8322 (ISSN-L)
- 1958-5969
- OpenAlex
- W2987960305
- Cited by
- 707
- References
- 101
- FWCI
- 21.47
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Podcasy, J. L., & Epperson, C. N. (2016). Considering sex and gender in Alzheimer disease and other dementias. Dialogues in Clinical Neuroscience. https://doi.org/10.31887/dcns.2016.18.4/cepperson
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.