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Close Relative of Human Middle East Respiratory Syndrome Coronavirus in Bat, South Africa
Open accessAbstract
The severe acute respiratory syndrome (SARS) outbreak of 2002–03 and the subsequent implication of bats as reservoir hosts of the causative agent, a coronavirus (CoV), prompted numerous studies of bats and the viruses they harbor. A novel clade 2c betacoronavirus, termed Middle East respiratory syndrome (MERS)–CoV, was recently identified as the causative agent of a severe respiratory disease that is mainly affecting humans on the Arabian Peninsula (1). Extending on previous work (2), we described European Pipistrellus bat–derived CoVs that are closely related to MERS-CoV (3). We now report the identification of a South Africa bat derived CoV that has an even closer phylogenetic relationship with MERS-CoV.
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Citations
Cited by
Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor
Ge, X.-Y., Li, J.-L., Yang, X.-L., Chmura, A. A., Zhu, G., Epstein, J. H., Mazet, J. K., Hu, B., Zhang, W., Peng, C., et al. (2013) · Nature · doi:10.1038/nature12711 · Cited by 1,778
Bat origin of human coronaviruses
Hu, B., Ge, X., Wang, L.-F., & Shi, Z. (2015) · Virology Journal · doi:10.1186/s12985-015-0422-1 · Cited by 344
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir
Mohd, H. A., Al-Tawfiq, J. A., & Memish, Z. A. (2016) · Virology Journal · doi:10.1186/s12985-016-0544-0 · Cited by 316
MERS-CoV spike protein: a key target for antivirals
Du, L., Yang, Y., Zhou, Y., Lu, L., Li, F., & Jiang, S. (2017) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2017.1271415 · Cited by 301
Klimstra, W. B., Tilston-Lunel, N. L., Nambulli, S., Boslett, J., McMillen, C. M., Gilliland, T., Dunn, M. D., Sun, C., Wheeler, S. E., Wells, A., et al. (2020) · Journal of General Virology · doi:10.1099/jgv.0.001481 · Cited by 137
Metadata
- Authors
- Ithete, N. L., Stoffberg, S., Corman, V. M., Cottontail, V. M., Richards, L. R., Schoeman, M. C., Drosten, C., Drexler, J. F., & Preiser, W.
- Venue
- Emerging Infectious Diseases
- Published
- 2013-10
- Volume
- 19
- Issue
- 10
- Pages
- 1697-1699
- ISSN
- 1080-6040 (ISSN-L)
- 1080-6059
- OpenAlex
- W2131369206
- Cited by
- 381
- References
- 0
- FWCI
- 31.19
- Type
- journal article
- Language
- en
- Open access
- diamond
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- CoChat. (2026). Citation check: Close Relative of Human Middle East Respiratory Syndrome Coronavirus in Bat, South Africa. https://app.cochat.ai/papers/10.3201/eid1910.130946
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- Ithete, N. L., Stoffberg, S., Corman, V. M., Cottontail, V. M., Richards, L. R., Schoeman, M. C., Drosten, C., Drexler, J. F., & Preiser, W. (2013). Close Relative of Human Middle East Respiratory Syndrome Coronavirus in Bat, South Africa. Emerging Infectious Diseases. https://doi.org/10.3201/eid1910.130946
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.