Cited by 316SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections StudiesZoonotic diseases and public health

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir

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Mohd, Hamzah A., Al-Tawfiq, Jaffar A., Memish, Ziad A.·2016·Virology Journal

Abstract

Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) is a novel coronavirus discovered in 2012 and is responsible for acute respiratory syndrome in humans. Though not confirmed yet, multiple surveillance and phylogenetic studies suggest a bat origin. The disease is heavily endemic in dromedary camel populations of East Africa and the Middle East. It is unclear as to when the virus was introduced to dromedary camels, but data from studies that investigated stored dromedary camel sera and geographical distribution of involved dromedary camel populations suggested that the virus was present in dromedary camels several decades ago. Though bats and alpacas can serve as potential reservoirs for MERS-CoV, dromedary camels seem to be the only animal host responsible for the spill over human infections.

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Authors
Mohd, H. A., Al-Tawfiq, J. A., & Memish, Z. A.
Affiliations
  • Ministry of Health (SA)
  • Alfaisal University (SA)
Corresponding author
Memish, Ziad A.
Venue
Virology Journal
Published
2016-06-03
Volume
13
Issue
1
Pages
87-87
ISSN
1743-422X (ISSN-L)
OpenAlex
W2411425451
Cited by
316
References
41
Citations by year
2026: 5 · 2025: 18 · 2024: 15 · 2023: 31 · 2022: 40 · 2021: 64 · 2020: 77 · 2019: 26 · 2018: 19 · 2017: 14 · 2016: 7
FWCI
3.38
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Virology Journal (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • IUScholarWorks (Indiana University) (submittedVersion, cc-by)
  • Zenodo (CERN European Organization for Nuclear Research) (submittedVersion, cc-by)
Topics
  • Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Virus Infections Studies
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Zoonotic diseases and public health
Keywords
MERS-CoV, zoonotic transmission, reservoir hosts, Camelus dromedarius, bats, alpaca, viral origin, phylogenetic analysis, seroprevalence, zoonotic spillover
MeSH terms
Africa, Animals, Camelids, New World, Camelus, Chiroptera, Disease Reservoirs, Humans, Zoonoses, Coronavirus Infections, Disease Transmission, Infectious, Middle East Respiratory Syndrome Coronavirus

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