Antimicrobial-Resistant Bacteria in Infected Wounds, Ghana, 20141
Open accessAbstract
Wound infections are an emerging medical problem worldwide, frequently neglected in under-resourced countries. Bacterial culture and antimicrobial drug resistance testing of infected wounds in patients in a rural hospital in Ghana identified no methicillin-resistant Staphylococcus aureus or carbapenem-resistant Enterobacteriaceae but identified high combined resistance of Enterobacteriaceae against third-generation cephalosporins and fluoroquinolones.
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Enterococcus showed high resistance prevalence of 100% to tetracycline and trimethoprim-sulfamethoxazole.
“Enterococcus showed high resistance prevalence of 100% to tetracycline [25,31], and trimethoprim-sulfamethoxazole [31].”
From A Systematic Review on Antimicrobial Resistance in Ghana from a One Health Perspective (2024) · cites this paper as [31]
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Cites
Human skin wounds: A major and snowballing threat to public health and the economy
Sen, C. K., Gordillo, G. M., Roy, S., Kirsner, R., Lambert, L., Hunt, T. K., Gottrup, F., Gurtner, G. C., & Longaker, M. T. (2009) · Wound Repair and Regeneration · doi:10.1111/j.1524-475x.2009.00543.x · Cited by 2,965 · cited 1× · see citing works
“Wound infections are an emerging medical problem worldwide; the economic burden and morbidity and mortality rates are huge (3,4).”
BackgroundDistrict Laboratory Practice in Tropical Countries
Cheesbrough, M. (2006) · Cambridge University Press eBooks · doi:10.1017/cbo9780511543470 · Cited by 1,946 · see citing works
Non-prescription antimicrobial use worldwide: a systematic review
Morgan, D. J., Okeke, I. N., Laxminarayan, R., Perencevich, E. N., & Weisenberg, S. (2011) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(11)70054-8 · Cited by 947 · cited 1× · see citing works
“indiscriminate use of antimicrobial drugs contributes to this factor (14).”
BackgroundMRSA in Africa: Filling the Global Map of Antimicrobial Resistance
Falagas, M. E., Karageorgopoulos, D. E., Leptidis, J., & Korbila, I. P. (2013) · PLoS ONE · doi:10.1371/journal.pone.0068024 · Cited by 237 · cited 1× · see citing works
“Such referrals predispose urban patients, staff, and others to more MRSA colonization and infection than experienced by those in rural areas (13).”
BackgroundLeopold, S. J., van Leth, F., Tarekegn, H., & Schultsz, C. (2014) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dku176 · Cited by 187 · cited 1× · see citing works
“coli, Klebsiella pneumoniae, and Enterobacter cloacae complex against third-generation cephalosporins, fluoroquinolones, or both (Table 2), as have been found in other studies from urban areas (3,5,10).”
ResultNtirenganya, C., Manzi, O., Muvunyi, C. M., & Ogbuagu, O. E. (2015) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.14-0607 · Cited by 129 · cited 5× · see citing works
“In contrast, studies from urban areas in sub-Saharan Africa countries found MRSA rates of >80% (10,12).”
BackgroundResultInfluentialManyahi, J., Matee, M. I., Majigo, M. V., Moyo, S. J., Mshana, S. E., & Lyamuya, E. (2014) · BMC Research Notes · doi:10.1186/1756-0500-7-500 · Cited by 128 · see citing works
Mengesha, R. E., Kasa, B. G., Saravanan, M., et al. (2014) · BMC Research Notes · doi:10.1186/1756-0500-7-575 · Cited by 126 · cited 1× · see citing works
“In contrast, studies from urban areas in sub-Saharan Africa countries found MRSA rates of >80% (10,12).”
ResultSurveillance for Antimicrobial Drug Resistance in Under-Resourced Countries
Vernet, G., Mary, C., Altmann, D. M., Doumbo, O. K., Morpeth, S. C., Bhutta, Z. A., & Klugman, K. P. (2014) · Emerging infectious diseases · doi:10.3201/eid2003.121157 · Cited by 106 · cited 3× · see citing works
“These data contribute to prevention and control of antimicrobial drug resistance (1).”
BackgroundKumburu, H. H., Sonda, T., Mmbaga, B. T., et al. (2017) · Tropical Medicine & International Health · doi:10.1111/tmi.12836 · Cited by 64 · cited 6× · see citing works
“Kumburu HH, Sonda T, Mmbaga BT, Alifrangis M, Lund O, Kibiki G, et al. Patterns of infections, aetiological agents and antimicrobial resistance at a tertiary care hospital in northern Tanzania.”
BackgroundResultInfluentialBacteremia and Antimicrobial Drug Resistance over Time, Ghana
Groß, U., Amuzu, S. K., de Ciman, R., Kassimova, I., Gross, L. K., Rabsch, W., Rosenberg, U., Schulze, M., Stich, A., & Zimmermann, O. (2011) · Emerging Infectious Diseases · doi:10.3201/eid1710.110327 · Cited by 47 · cited 4× · see citing works
“Antimicrobial resistance testing was repeated with VITEK 2 (bioMérieux, Marcy-l’Étoile, France) at the Institute for Medical Microbiology by using AST-P632, AST-P586, AST-N214, and AST-N248 cards with respect to bacterial species and according to the breakpoint tables for interpretation Antimicrobial-Resistant Bacteri…”
BackgroundInfluentialSelf-citationBacteremia and Antimicrobial Drug Resistance over Time, Ghana
Groß, U., Amuzu, S. K., de Ciman, R., Kassimova, I., Groß, L., Rabsch, W., Rosenberg, U., Schulze, M. H., Stich, A., & Zimmermann, O. (2011) · Emerging infectious diseases · doi:10.3201/edi1710.110327 · Cited by 41 · see citing works
Self-citationAntibiotic Resistance: The Need For a Global Strategy
Elder, D. P., Kuentz, M., & Holm, R. (2016) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2016.06.002 · Cited by 29 · cited 1× · see citing works
“Development of antimicrobial drug resistance may also be enhanced by circulation of counterfeit drugs (15).”
BackgroundSeasonal variation and risk factors associated with surgical site infection rate in Kano, Nigeria
Nwankwo, E. O., & Edino, S. (2014) · TURKISH JOURNAL OF MEDICAL SCIENCES · doi:10.3906/sag-1305-47 · Cited by 29 · cited 3× · see citing works
“Nwankwo E, Edino S. Seasonal variation and risk factors associated with surgical site infection rate in Kano, Nigeria.”
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Flagged first, then by citations
Cited by
Sorted by citations
Antimicrobial action of autologous platelet-rich plasma on MRSA-infected skin wounds in dogs
Farghali, H. A. M. A., AbdElKader, N. A., AbuBakr, H. O., Aljuaydi, S. H., Khattab, M. S., Elhelw, R. A., & Elhariri, M. (2019) · Scientific Reports · doi:10.1038/s41598-019-48657-5 · Cited by 83 · see citing works
“present < 33% (2), present 33–66% (3), intensively present (4) and the degree of stromal necrosis according to the following scale; 1 (minimal) < 10%, 2 (mild) 10–25%, 3 (moderate) up to 50%, 4 (marked) up to 75%31,32.”
Kouhbanani, M. A. J., Mosleh-Shirazi, S., Beheshtkhoo, N., et al. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.104541 · Cited by 63 · see citing works
A Systematic Review on Antimicrobial Resistance in Ghana from a One Health Perspective
Donkor, E. S., Odoom, A., Osman, A.-H., Darkwah, S., & Kotey, F. C. N. (2024) · Antibiotics · doi:10.3390/antibiotics13070662 · Cited by 52 · see citing works
Sisay, M., Worku, T., & Edessa, D. (2019) · BMC Pharmacology and Toxicology · doi:10.1186/s40360-019-0315-9 · Cited by 54 · see citing works
Monk, E. J. M., Jones, T. P., Bongomin, F., Kibone, W., Nsubuga, Y., Ssewante, N., Muleya, I., Nsenga, L., Rao, B., & van Zandvoort, K. (2024) · PLOS Global Public Health · doi:10.1371/journal.pgph.0003077 · Cited by 50 · see citing works
Colonization of HIV-Infected Children with Methicillin-Resistant Staphylococcus aureus
Donkor, E. S., Kotey, F. C. N., Dayie, N. T. K. D., Duodu, S., Tetteh‐Quarcoo, P. B., Osei, M., & Tette, E. M. A. (2019) · Pathogens · doi:10.3390/pathogens8010035 · Cited by 34 · see citing works
Krumkamp, R., Oppong, K., Hogan, B., Strauss, R. A., Frickmann, H., Akenten, C. W., Boahen, K. G., Rickerts, V., Smith, I. M., Groß, U., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0237263 · Cited by 30 · see citing works
Self-citationMonnheimer, M., Cooper, P., Amegbletor, H. K., et al. (2021) · Microorganisms · doi:10.3390/microorganisms9030537 · Cited by 26 · see citing works
Self-citationPankok, F., Taudien, S., Dekker, D. M., et al. (2022) · Antibiotics · doi:10.3390/antibiotics11050689 · Cited by 23 · see citing works
Venne, D. M., Hartley, D., Malchione, M. D., Koch, M., Britto, A. Y., & Goodman, J. L. (2023) · Antimicrobial Resistance and Infection Control · doi:10.1186/s13756-023-01220-4 · Cited by 26 · see citing works
Risk stratification for multidrug-resistant bacteria in patients with skin and soft tissue infection
Barbier, F., & Timsit, J. (2020) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0000000000000642 · Cited by 22 · see citing works
“These rates were 47 and 46%, respectively, in another hospital-based study conducted in 2014 in Ghana [51].”
ResultSandar, W. P., Saw, S., Kumar, A. M. V., et al. (2021) · Tropical Medicine and Infectious Disease · doi:10.3390/tropicalmed6020080 · Cited by 21 · see citing works
“In other studies, the most common bacteria were Staphylococcus aureus [8,10,22,23].”
BackgroundResultWolters, M., Frickmann, H., Christner, M., Both, A., Rohde, H., Oppong, K., Akenten, C. W., May, J., & Dekker, D. M. (2020) · Microorganisms · doi:10.3390/microorganisms8122052 · Cited by 19 · see citing works
Song, S., Li, Z., Li, J., et al. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c03655 · Cited by 17 · see citing works
Abdu, D. A. B., Egbagba, D. J., & Fente, D. B. G. (2019) · Tropical Journal of Pathology and Microbiology · doi:10.17511/jopm.2019.i12.01 · Cited by 14 · see citing works
Krumkamp, R., Oppong, K., Hogan, B., Strauss, R., Frickmann, H., Wiafe-Akenten, C., Boahen, K., Rickerts, V., McCormick, I., Groß, U., et al. (2020) · doi:10.21203/rs.3.rs-16528/v1 · Cited by 15 · see citing works
Self-citationDekker, D. M., Pankok, F., Thye, T., et al. (2021) · Antibiotics · doi:10.3390/antibiotics10030339 · Cited by 10 · see citing works
Asiedu, S. O., Kini, P., Aglomasa, B. C., Amewu, E. K. A., Asiedu, E., Wireko, S., Boahen, K. G., Berbudi, A., Sylverken, A. A., & Kwarteng, A. (2022) · Health Science Reports · doi:10.1002/hsr2.724 · Cited by 9 · see citing works
Antibiotic Resistant Bacteria Infecting Wounds of Rural Community Dwellers in Northern Ghana
Vicar, E. K., Acquah, S. E. K., Walana, W., et al. (2021) · European Journal of Medical and Health Sciences · doi:10.24018/ejmed.2021.3.1.678 · Cited by 9 · see citing works
Wound Management Property of a Hydroethanolic Leaf Extract of Cnestis ferruginea DC
Yakubu, J., Koffuor, G. A., Atsu-Nunyawu, T., et al. (2021) · Advances in Pharmacological and Pharmaceutical Sciences · doi:10.1155/2021/6693718 · Cited by 6 · see citing works
Tian, Z., Gao, J. J., & Qin, W. (2018) · Madridge Journal of Analytical Sciences and Instrumentation · doi:10.18689/mjai-1000112 · Cited by 6 · see citing works
“Fluoroquinolones (FQs) are antibiotics for both pathogenic Gram-negative and Gram-positive bacteria and can inhibit bacterial DNA synthesis [1].”
BackgroundSah, A. K., & Feglo, P. K. (2022) · Pan African Medical Journal · doi:10.11604/pamj.2022.43.207.33734 · Cited by 4 · see citing works
Yeboaa, C., Odoi, H., Ntim, R. O., et al. (2023) · Archives of Microbiology · doi:10.1007/s00203-023-03411-4 · Cited by 4 · see citing works
Baguma, A., Musinguzi, B., Kagirita, A. A., et al. (2020) · doi:10.21203/rs.3.rs-17292/v1 · Cited by 3 · see citing works
“from Ukrainian military hospital who reported Gram negative bacteria as the predominating pathogens in wound infections [17, 18, 19].”
BackgroundMkinga, D. A., & Lyamuya, F. S. (2022) · East Africa Science · doi:10.24248/easci.v4i1.59 · Cited by 3 · see citing works
Adesida, S. A., Iyebeye, M. I., Aina, O. O., et al. (2022) · Beni-Suef University Journal of Basic and Applied Sciences · doi:10.1186/s43088-022-00272-6 · Cited by 2 · see citing works
“Its involvement in wound infections is becoming a major medical issue around the world [12].”
BackgroundLarue, L., Michely, L., Moreno, X., Pirès, R., Pawlak, A., Grande, D., & Belbekhouche, S. (2024) · Materials Advances · doi:10.1039/d3ma01140b · Cited by 2 · see citing works
Assessment of Wound Healing Properties of Medicinal Plants: The Case of Berlinia confusa
Adjei, S., Amponsah, I. K., Ekuadzi, E., Hamilton, C., Gavrilović, J., Dillon, O., El‐Demerdash, A., & Asante-Kwatia, E. (2025) · Natural Product Communications · doi:10.1177/1934578x241311978 · Cited by 1 · see citing works
Abubakari, A. W., Agbeko, R., Osei‐Adjei, G., & Kümmerli, R. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1696696 · Cited by 1 · see citing works
Al-najar, F. M., Atiyea, Q. M., & Al-Azzawie, A. F. (2022) · Tikrit Journal of Pure Science · doi:10.25130/tjps.v26i2.116 · Cited by 1 · see citing works
Pallavali, R. R., Degati, V. L., & Durbaka, V. R. P. (2019) · Preprints.org · doi:10.20944/preprints201906.0094.v1 · Cited by 1 · see citing works
Antimicrobial Resistance and Virulence Mechanisms
Oliveira, M. (2022) · MDPI eBooks · doi:10.3390/books978-3-0365-3905-8
Alsaadi, A., Hegazy, E. E., Shoukr, T. G., et al. (2022) · The Egyptian Journal of Medical Microbiology · doi:10.21608/ejmm.2022.247173
“On the other hand, in another study by Janssen et al., 14 it was reported that, of the 67 wound swab samples, infection was monomicrobial in 17 (25.4”
ResultInfluentialPhylogenic diversity some of the pseudomonas Isolate from wound infection in Babylon province
Hussein, A. A., & Al-Yassari, A.-K. S. (2022) · International Journal of Health Sciences · doi:10.53730/ijhs.v6ns6.10520
“The predominant bacterial isolates from the infected wounds include Staphylococcus aureus, Escherichia coli, Proteus species, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii (Janssen et al., 2018).”
BackgroundBaidoo, E. A., Boamah, V. E., Odoi, H., et al. (2025) · African Health Sciences · doi:10.4314/ahs.v25i2.4
Agyekum, E. K., Thiele, J., Bukari, M. I. S., et al. (2026) · Antibiotics · doi:10.3390/antibiotics15100959
“…pathogens in the Ghanaian cohort is consistent with previous studies from Ghana and other sub-Saharan African countries, which have repeatedly identified Enterobacterales and Pseudomonas aeruginosa among the leading pathogens isolated from chronic and postoperative wound infections [10–13].”
- Authors
- Janssen, H., Janssen, I., Cooper, P., Kainyah, C., Pellio, T., Quintel, M., Monnheimer, M., Groß, U., & Schulze, M. H.
- Affiliations
- Universitätsmedizin Göttingen (DE)
- Corresponding author
- Schulze, Marco H.
- Venue
- Emerging Infectious Diseases
- Published
- 2018-05
- Volume
- 24
- Issue
- 5
- Pages
- 916-919
- ISSN
- 1080-6040 (ISSN-L)
- 1080-6059
- PMC
- PMC5938797
- OpenAlex
- W2789357809
- Semantic Scholar
- 40e8192da14d3495795e4224fc6ab350f7abacf5
- Cited by
- 36
- References
- 14
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 4 · 2023: 3 · 2022: 9 · 2021: 5 · 2020: 5 · 2019: 5 · 2018: 1
- FWCI
- 1.51
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by
- Locations
- Emerging infectious diseases (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Antibiotic Resistance in Bacteria
- Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antibiotic Use and Resistance
- Health Sciences › Medicine › Infectious Diseases › Antimicrobial Resistance in Staphylococcus
- Keywords
- antimicrobial resistance, wound infection, Enterobacteriaceae, third-generation cephalosporin resistance, fluoroquinolone resistance, methicillin-resistant Staphylococcus aureus, carbapenem resistance, rural hospitals, Ghana
- MeSH terms
- Anti-Bacterial Agents, Bacteria, Ghana, Humans, Wound Infection, Drug Resistance, Bacterial
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