Cited by 484Alzheimer's disease research and treatmentsDementia and Cognitive Impairment ResearchNeurology and Historical Studies

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Alzheimer's disease: The amyloid cascade hypothesis: An update and reappraisal

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Hardy, John·2006·Journal of Alzheimer s Disease

DOI 10.3233/jad-2006-9s317

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Abstract

Here I recap the scientific and personal background of the delineation of the amyloid cascade hypothesis for Alzheimer's disease that I wrote with Gerry Higgins and the events leading to the writing of that influential review.

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Authors: Hardy, J.
Affiliations: National Institutes of Health (US)
Corresponding author: Hardy, John
ORCID: Hardy, John
Venue: Journal of Alzheimer s Disease
Publisher: SAGE Publications
Published: 2006-07-27
Volume: 9
Issue: s3
Pages: 151-153
ISSN: 1387-2877 (ISSN-L)
1875-8908
DOI: 10.3233/jad-2006-9s317
OpenAlex: W1746907828
Cited by: 475
References: 13
Citations by year: 2026: 12 · 2025: 15 · 2024: 21 · 2023: 22 · 2022: 17 · 2021: 29 · 2020: 35 · 2019: 30 · 2018: 34 · 2017: 28 · 2016: 22 · 2015: 31 · 2014: 25 · 2013: 29 · 2012: 25
FWCI: 14.14
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Journal of Alzheimer s Disease (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Life Sciences › Neuroscience › Neurology › Neurology and Historical Studies
Keywords: Alzheimer's disease, amyloid hypothesis
MeSH terms: Alzheimer Disease, Brain, Humans, Amyloid beta-Peptides

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Alzheimer's disease: The amyloid cascade hypothesis: An update and reappraisal

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