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The Genetic Defect Causing Familial Alzheimer's Disease Maps on Chromosome 21

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Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

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The Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception

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SYMPOSIUM: Clearance of Aβ from the Brain in Alzheimer's Disease: Perivascular Drainage of Amyloid‐β Peptides from the Brain and Its Failure in Cerebral Amyloid Angiopathy and Alzheimer's Disease

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Half a century of amyloids: past, present and future

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Alzheimer disease therapy—moving from amyloid-β to tau

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The Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception

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Locus‐specific mutation databases for neurodegenerative brain diseases

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Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative

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Insulin resistance is associated with the pathology of Alzheimer disease: The Hisayama Study

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Apolipoprotein e sets the stage: response to injury triggers neuropathology

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Natural products as a source of Alzheimer's drug leads

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Increased Iron and Free Radical Generation in Preclinical Alzheimer Disease and Mild Cognitive Impairment

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Review: Systemic inflammation andAlzheimer's disease

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2014 Update of the Alzheimer’s Disease Neuroimaging Initiative: A review of papers published since its inception

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Patterns of microRNA expression in normal and early Alzheimer's disease human temporal cortex: white matter versus gray matter

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MicroRNAs (miRNAs) in Neurodegenerative Diseases

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A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ

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Clinicopathologic Correlations in a Large Alzheimer Disease Center Autopsy Cohort: Neuritic Plaques and Neurofibrillary Tangles "Do Count" When Staging Disease Severity

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The amyloid cascade hypothesis: an updated critical review

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Resveratrol: from enhanced biosynthesis and bioavailability to multitargeting chronic diseases

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Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer’s Disease

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Cellular senescence and Alzheimer disease: the egg and the chicken scenario

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The up‐regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1α

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Zebrafish: an emerging real-time model system to study Alzheimer’s disease and neurospecific drug discovery

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Lipid Rafts: Linking Alzheimer′s Amyloid‐βProduction, Aggregation, and Toxicity at Neuronal Membranes

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Cellular and pathological heterogeneity of primary tauopathies

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A label-free electrical impedimetric biosensor for the specific detection of Alzheimer's amyloid-beta oligomers

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Label-free imaging of amyloid plaques in Alzheimer’s disease with stimulated Raman scattering microscopy

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Resveratrol and Neuroprotection: Impact and Its Therapeutic Potential in Alzheimer's Disease

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Adiponectin suppresses amyloid-β oligomer (AβO)-induced inflammatory response of microglia via AdipoR1-AMPK-NF-κB signaling pathway

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A Common Biological Mechanism in Cancer and Alzheimers Disease?

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Effect of reductions in amyloid levels on cognitive change in randomized trials: instrumental variable meta-analysis

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Temsirolimus promotes autophagic clearance of amyloid-β and provides protective effects in cellular and animal models of Alzheimer's disease

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APOE‐modulated Aβ‐induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective

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Levels of Soluble Apolipoprotein E/Amyloid-β (Aβ) Complex Are Reduced and Oligomeric Aβ Increased with APOE4 and Alzheimer Disease in a Transgenic Mouse Model and Human Samples*

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Signaling pathway cross talk in Alzheimer’s disease

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Nanocomposites Inhibit the Formation, Mitigate the Neurotoxicity, and Facilitate the Removal of β-Amyloid Aggregates in Alzheimer’s Disease Mice

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Alzheimer’s disease: How metal ions define β-amyloid function

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Aging, lifestyle and dementia

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Nanoparticle–chelator conjugates as inhibitors of amyloid-β aggregation and neurotoxicity: A novel therapeutic approach for Alzheimer disease

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A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's disease

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Resveratrol as a Therapeutic Agent for Alzheimer’s Disease

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The voltage-dependent anion channel 1 mediates amyloid β toxicity and represents a potential target for Alzheimer disease therapy

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The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM

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Intraneuronal tau aggregation precedes diffuse plaque deposition, but amyloid-β changes occur before increases of tau in cerebrospinal fluid

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Advances in the pathogenesis of Alzheimer’s disease: a re-evaluation of amyloid cascade hypothesis

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Current and emerging avenues for Alzheimer's disease drug targets

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Amyloid-β in Alzheimer Disease: The Null versus the Alternate Hypotheses

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The Amygdala as a Locus of Pathologic Misfolding in Neurodegenerative Diseases

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Cholesterol and Alzheimer’s Disease Risk: A Meta-Meta-Analysis

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Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease

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Orientin alleviates cognitive deficits and oxidative stress in Aβ1–42-induced mouse model of Alzheimer's disease

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March separate, strike together — Role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease

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Chronic Aluminum Intake Causes Alzheimer's Disease: Applying Sir Austin Bradford Hill's Causality Criteria

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Shift in brain metabolism in late onset Alzheimer’s disease: Implications for biomarkers and therapeutic interventions

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The amyloid cascade and Alzheimer's disease therapeutics: theory versus observation

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Alzheimer’s disease due to loss of function: A new synthesis of the available data

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Iron overload accelerates neuronal amyloid-β production and cognitive impairment in transgenic mice model of Alzheimer's disease

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All-transretinoic acid as a novel therapeutic strategy for Alzheimer’s disease

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P-Glycoprotein and Breast Cancer Resistance Protein Restrict Apical-to-Basolateral Permeability of Human Brain Endothelium to Amyloid-β

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Neurodegeneration and Alzheimer's disease (AD). What Can Proteomics Tell Us About the Alzheimer's Brain?

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Soluble apoE/Aβ complex: mechanism and therapeutic target for APOE4-induced AD risk

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Brains With Medial Temporal Lobe Neurofibrillary Tangles But No Neuritic Amyloid Plaques Are a Diagnostic Dilemma But May Have Pathogenetic Aspects Distinct From Alzheimer Disease

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Amyloid-β-induced occludin down-regulation and increased permeability in human brain endothelial cells is mediated by MAPK activation

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Nanotechnology-Based Drug Delivery Systems for Targeting, Imaging and Diagnosis of Neurodegenerative Diseases

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Tau and mTOR: The Hotspots for Multifarious Diseases in Alzheimer's Development

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Diet Quality Is Associated with Better Cognitive Test Performance among Aging Men and Women ,

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Cholinergic basal forebrain atrophy predicts amyloid burden in Alzheimer's disease

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Association of Alzheimer disease pathology with abnormal lipid metabolism

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Menopause, obesity and inflammation: interactive risk factors for Alzheimer’s disease

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Amyloid-β oligomers stimulate microglia through a tyrosine kinase dependent mechanism

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Activation of the amyloid cascade in apolipoprotein E4 transgenic mice induces lysosomal activation and neurodegeneration resulting in marked cognitive deficits

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Baicalein suppresses Repeat Tau fibrillization by sequestering oligomers

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Estrogen Regulation of Mitochondrial Bioenergetics

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Upregulation of miR-181 Decreases c-Fos and SIRT-1 in the Hippocampus of 3xTg-AD Mice

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Aging and Down Syndrome

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Tau and TDP-43 proteinopathies: kindred pathologic cascades and genetic pleiotropy

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Interactions between Amyloid-β and Hemoglobin: Implications for Amyloid Plaque Formation in Alzheimer's Disease

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Correspondence to Author:

Behera, S. K., Behera, R. K., Barik, M. R., & Lokhande, R. S. (2013)

doi:10.1155/2012/369808 Review Article Alzheimer’s Disease and the Amyloid Cascade Hypothesis: A Critical Review

Reitz, C. (2012)

Journal of Neurochemistry special issue on Alzheimer’s disease: ‘amyloid cascade hypothesis – 20 years on’

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