Alzheimer's disease: The amyloid cascade hypothesis: An update and reappraisal

The Amyloid Hypothesis of Alzheimer’s Disease: Progress and Problems on the Road to Therapeutics

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Alzheimer's disease: the amyloid cascade hypothesis

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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Amyloid deposition as the central event in the aetiology of Alzheimer’s disease

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Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

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Mutation of the Alzheimer's Disease Amyloid Gene in Hereditary Cerebral Hemorrhage, Dutch Type

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The Genetic Defect Causing Familial Alzheimer's Disease Maps on Chromosome 21

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Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

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Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau

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The isolation and amino acid composition of senile plaque core protein

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A human carboxypeptidase E/NF-α1 gene mutation in an Alzheimer’s disease patient leads to dementia and depression in mice

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Production of an anti-Aβ antibody fragment in Pichia pastoris and in vitro and in vivo validation of its therapeutic effect

Montoliu‐Gaya, L., Esquerda-Canals, G., Bronsoms, S., & Villegas, S. (2017) · PLoS ONE · doi:10.1371/journal.pone.0181480 · Cited by 31

Low and High Molecular Weight FGF-2 Have Differential Effects on Astrocyte Proliferation, but Are Both Protective Against Aβ-Induced Cytotoxicity

Chen, X., Li, Z., Cheng, Y., Kardami, E., & Loh, Y. P. (2020) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00328 · Cited by 30

Chronic noise exposure exacerbates AD-like neuropathology in SAMP8 mice in relation to Wnt signaling in the PFC and hippocampus

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Use of biomarkers and imaging to assess pathophysiology, mechanisms of action and target engagement

Hampel, H. J., & Lista, S. (2013) · The journal of nutrition health & aging · doi:10.1007/s12603-013-0003-1 · Cited by 29

A copper-binding site in the cytoplasmic domain of BACE1 identifies a possible link to metal homoeostasis and oxidative stress in Alzheimer's disease

Dingwall, C. (2007) · Biochemical Society Transactions · doi:10.1042/bst0350571 · Cited by 29

Emerging amyloid beta (Ab) peptide modulators for the treatment of Alzheimer's disease (AD)

Lukiw, W. J. (2008) · Expert Opinion on Emerging Drugs · doi:10.1517/14728214.13.2.255 · Cited by 29

Long-term exposure to ELF-MF ameliorates cognitive deficits and attenuates tau hyperphosphorylation in 3xTg AD mice

Hu, Y., Lai, J., Wan, B., Liu, X., Zhang, Y., Zhang, J., Sun, D., Ruan, G., Liu, E., Liu, G., et al. (2016) · NeuroToxicology · doi:10.1016/j.neuro.2016.02.012 · Cited by 28

Nantenine as an acetylcholinesterase inhibitor: SAR, enzyme kinetics and molecular modeling investigations

Pecic, S., McAnuff, M. A., & Harding, W. W. (2010) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.3109/14756361003671078 · Cited by 27

Fluorinated benzophenone derivatives: Balanced multipotent agents for Alzheimer's disease

Belluti, F., Simone, A. D., Tarozzi, A., Bartolini, M., Djemil, A., Bisi, A., Gobbi, S., Montanari, S., Cavalli, A., Andrisano, V., et al. (2014) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2014.03.042 · Cited by 27

Protein nitration profile of CD3+ lymphocytes from Alzheimer disease patients: Novel hints on immunosenescence and biomarker detection

Tramutola, A., Abate, G., Lanzillotta, C., Triani, F., Barone, E., Iavarone, F., Vincenzoni, F., Castagnola, M., Marziano, M., Memo, M., et al. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.10.414 · Cited by 26

Finite-time stability and optimal control of a stochastic reaction-diffusion model for Alzheimer’s disease with impulse and time-varying delay

Hu, J., Zhang, Q., Meyer‐Baese, A., & Ye, M. (2021) · Applied Mathematical Modelling · doi:10.1016/j.apm.2021.10.004 · Cited by 26

Molecular dynamics simulation of aluminium binding to amyloid-β and its effect on peptide structure

Turner, M., Mutter, S. T., Kennedy-Britten, O. D., & Platts, J. A. (2019) · PLoS ONE · doi:10.1371/journal.pone.0217992 · Cited by 26

Neuroprotective role of alendronate against APP processing and neuroinflammation in mice fed a high fat diet

Zameer, S., Alam, M. M., Hussain, S., Vohora, D., Ali, J., Najmi, A. K., & Akhtar, M. (2020) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2020.04.010 · Cited by 26

p-Benzoquinone as a Privileged Scaffold of Pharmacological Significance: A Review

Silakari, P., Priyanka, P., & Piplani, P. (2020) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/1389557520666200429101451 · Cited by 25

An ongoing journey of chalcone analogues as single and multi-target ligands in the field of Alzheimer's disease: A review with structural aspects

Sharma, P., & Singh, M. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.121568 · Cited by 25

Advances in Recent Patent and Clinical Trial Drug Development for Alzheimer’s Disease

Liu, H., Wang, L., Su, W., & Xie, X. (2014) · Pharmaceutical Patent Analyst · doi:10.4155/ppa.14.22 · Cited by 26

Mini Review: Opposing Pathologies in Cancer and Alzheimer's Disease: Does the PI3K/Akt Pathway Provide Clues?

Barker, R. M., Holly, J. M. P., Biernacka, K. M., Allen, S. J., & Perks, C. M. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00403 · Cited by 25

Finding the falsification threshold of the toxic proteinopathy hypothesis in neurodegeneration

Espay, A. J., Herrup, K., & Daly, T. P. (2023) · Handbook of clinical neurology · doi:10.1016/b978-0-323-85538-9.00008-0 · Cited by 27

Preventing Alzheimer's disease by means of natural selection

Demetrius, L., & Driver, J. A. (2014) · Journal of The Royal Society Interface · doi:10.1098/rsif.2014.0919 · Cited by 24

Alzheimer's disease biomarkers in animal models: closing the translational gap.

Sabbagh, J. J., Kinney, J. W., & Cummings, J. L. (2013) · Europe PMC (PubMed Central) · Cited by 24

Iron Chelation Inhibits Osteoclastic Differentiation In Vitro and in Tg2576 Mouse Model of Alzheimer’s Disease

Guo, J.-P., Pan, J., Xiong, L., Xia, W.-F., Cui, S., & Xiong, W. (2015) · PLoS ONE · doi:10.1371/journal.pone.0139395 · Cited by 24

Computing the Pathogenicity of Alzheimer’s Disease Presenilin 1 Mutations

Tang, N., Dehury, B., & Kepp, K. P. (2019) · Journal of Chemical Information and Modeling · doi:10.1021/acs.jcim.8b00896 · Cited by 23

A quantitative model of human neurodegenerative diseases involving protein aggregation

Kepp, K. P. (2019) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2019.04.001 · Cited by 23

Discovery and Characterization of Selective and Ligand-Efficient DYRK Inhibitors

Henderson, S. H., Sorrell, F. J., Bennett, J. M., Fedorov, O., Hanley, M. T., Godoi, P. H., de Sousa, R. R. R., Robinson, S. W., Ashall-Kelly, A., Navratilova, I. H., et al. (2021) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.1c01115 · Cited by 23

Factors influencing accuracy of cortical thickness in the diagnosis of Alzheimer's disease

Mahanand, B. S., Fischl, B. R., Salat, D. H., & Initiative, A. D. N. (2017) · Human Brain Mapping · doi:10.1002/hbm.23922 · Cited by 23

Amino acid-functionalized chitosan beads for in vitro copper ions uptake in the presence of histidine

Taketa, T. B., Mahl, C. R. A., Calais, G. B., & Beppu, M. M. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.08.017 · Cited by 23

High Glycemic Diet Is Related to Brain Amyloid Accumulation Over One Year in Preclinical Alzheimer's Disease

Taylor, M., Sullivan, D. K., Morris, J. K., Vidoni, E. D., Honea, R. A., Mahnken, J. D., & Burns, J. M. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.741534 · Cited by 28

Mechanism-based treatments for Alzheimer's disease

Davies, P., & Koppel, J. L. (2009) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2009.11.2/pdavies · Cited by 23

Development of iron chelator–nanoparticle conjugates as potential therapeutic agents for Alzheimer disease

Liu, G., Men, P., Perry, G. L., & Smith, M. A. (2009) · Progress in brain research · doi:10.1016/s0079-6123(08)80005-2 · Cited by 22

Cell size effects in the molecular dynamics of the intrinsically disordered Aβ peptide

Mehra, R., & Kepp, K. P. (2019) · The Journal of Chemical Physics · doi:10.1063/1.5115085 · Cited by 22

Experimental Inhibition of Fibrillogenesis and Neurotoxicity by amyloid-beta (Aβ) and Other Disease-Related Peptides/Proteins by Plant Extracts and Herbal Compounds

Kumar, S., Okello, E. J., & Harris, J. R. (2012) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-94-007-5416-4_13 · Cited by 23

Effect of bFGF on neuronal damage induced by sequential treatment of amyloid β and excitatory amino acid in vitro and in vivo

Noshita, T., Murayama, N., Oka, T., Ogino, R., Nakamura, S., & Inoue, T. (2012) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2012.09.020 · Cited by 22

Classifying Early and Late Mild Cognitive Impairment Stages of Alzheimer’s Disease by Analyzing Different Brain Areas

Uysal, G., & Öztürk, M. (2020) · Medical Technologies Congress (TIPTEKNO) · doi:10.1109/tiptekno50054.2020.9299217 · Cited by 21

Magnolol extends lifespan and improves age-related neurodegeneration in Caenorhabditis elegans via increase of stress resistance

Yu, J., Gao, X., Zhang, L., Shi, H., Yan, Y., Han, Y., Wu, C., Liu, Y., Fang, M., Huang, C., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-53374-9 · Cited by 21

Role of Hybrid Brain Imaging in Neuropsychiatric Disorders

Burhan, A. M., Marlatt, N. E., Palaniyappan, L. K., Anazodo, U., & Prato, F. S. (2015) · Diagnostics · doi:10.3390/diagnostics5040577 · Cited by 21

Differential effects of apoE and apoJ mimetic peptides on the action of an anti-Aβ scFv in 3xTg-AD mice

Montoliu‐Gaya, L., Güell‐Bosch, J., Esquerda-Canals, G., Roda, A. R., Serra-Mir, G., Lope‐Piedrafita, S., Sánchez‐Quesada, J. L., & Villegas, S. (2018) · Biochemical Pharmacology · doi:10.1016/j.bcp.2018.07.012 · Cited by 23

Preventing Effect of L-Type Calcium Channel Blockade on Electrophysiological Alterations in Dentate Gyrus Granule Cells Induced by Entorhinal Amyloid Pathology

Pourbadie, H. G., Naderi, N., Mehranfard, N., Janahmadi, M., Khodagholi, F., & Motamedi, F. (2015) · PLoS ONE · doi:10.1371/journal.pone.0117555 · Cited by 21

Multifunctional mesoporous nanoselenium delivery of metformin breaks the vicious cycle of neuroinflammation and ROS, promotes microglia regulation and alleviates Alzheimer's disease

Guo, X., Zhang, B., Chen, Y., Zhi, J., Yuan, X., Zhang, L., Liu, J., & Liu, Y. (2024) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2024.114300 · Cited by 20

Computational analysis of Alzheimer-causing mutations in amyloid precursor protein and presenilin 1

Mehra, R., & Kepp, K. P. (2019) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2019.108168 · Cited by 20

PET Neuroimaging in Dementia Conditions

Perani, D., Caminiti, S. P., Carli, G., & Tondo, G. (2020) · Springer eBooks · doi:10.1007/978-3-030-53168-3_9 · Cited by 20

Senile plaques in Alzheimer's disease arise from Aβ‐ and Cathepsin D‐enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture

Fu, H., Li, J., Du, P., Jin, W., Gao, G., & Cui, D. (2022) · FEBS Letters · doi:10.1002/1873-3468.14549 · Cited by 20

The protective effect of curcumin on Aβ induced aberrant cell cycle reentry on primary cultured rat cortical neurons.

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Development, Optimization and Use of Preclinical Behavioral Models to Maximize the Productivity of Drug Discovery for Alzheimer's Disease

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Metal Binding to Amyloid-β1–42: A Ligand Field Molecular Dynamics Study

Mutter, S. T., Turner, M., Deeth, R. J., & Platts, J. A. (2018) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.8b00210 · Cited by 20

Structural Determinant of β-Amyloid Formation: From Transmembrane Protein Dimerization to β-Amyloid Aggregates

Papadopoulos, N., Suelves, N., Perrin, F., Vadukul, D. M., Vrancx, C., Constantinescu, S. N., & Kienlen-Campard, P. (2022) · Biomedicines · doi:10.3390/biomedicines10112753 · Cited by 20

TMEM59 Haploinsufficiency Ameliorates the Pathology and Cognitive Impairment in the 5xFAD Mouse Model of Alzheimer’s Disease

Meng, J., Han, L., Zheng, N., Xu, H., Liu, Z., Zhang, X., Luo, H., Can, D., Sun, H., Xu, H., et al. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.596030 · Cited by 19

The supersaturation perspective on the amyloid hypothesis

Barron, D. P., & Guo, Z. (2023) · Chemical Science · doi:10.1039/d3sc03981a · Cited by 18

Prognostic Role of CSF β-amyloid 1–42/1–40 Ratio in Patients Affected by Amyotrophic Lateral Sclerosis

Colletti, T., Agnello, L., Spataro, R., Guccione, L., Notaro, A., Sasso, B. L., Blandino, V., Graziano, F., Gambino, C. M., Giglio, R. V., et al. (2021) · Brain Sciences · doi:10.3390/brainsci11030302 · Cited by 19

Spongiapyridine and Related Spongians Isolated from an Indonesian Spongia sp.

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Design, Synthesis, and Biological Evaluation of Novel Chromanone Derivatives as Multifunctional Agents for the Treatment of Alzheimer’s Disease

Li, X., Li, T., Zhan, F., Cheng, F., Lu, L., Zhang, B., Li, J., Hu, Z., Zhou, S., Jia, Y., et al. (2022) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.2c00520 · Cited by 18

Alzheimer's disease models and functional genomics—How many needles are there in the haystack?

Götz, J., Matamales, M., Götz, N. N., Ittner, L. M., & Eckert, A. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00320 · Cited by 19

Flavonoids and their derivatives with β-amyloid aggregation inhibitory activity from the leaves and twigs of Pithecellobium clypearia Benth

Wang, Y.-X., Ren, Q., Yan, Z., Wang, W., Zhao, L., Bai, M., Wang, X., Huang, X., & Song, S. (2017) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2017.09.051 · Cited by 18

Multivariate regression analysis of structural MRI connectivity matrices in Alzheimer’s disease

Rasero, J., Amoroso, N., Rocca, M. L., Tangaro, S., Bellotti, R., Stramaglia, S., & Initiative, A. D. N. (2017) · PLoS ONE · doi:10.1371/journal.pone.0187281 · Cited by 18

Characterization of monomeric and soluble aggregated Aβ in Down’s syndrome and Alzheimer’s disease brains

Gkanatsiou, E., Sahlin, C., Portelius, E., Johannesson, M., Söderberg, L., Fälting, J. M., Basun, H., Möller, C., Odergren, T., Zetterberg, H., et al. (2021) · Neuroscience Letters · doi:10.1016/j.neulet.2021.135894 · Cited by 18

Neuroprotective Effect of NO-Delivery Dinitrosyl Iron Complexes (DNICs) on Amyloid Pathology in the Alzheimer’s Disease Cell Model

Chuang, W.-H., Chou, Y.-T., Chen, Y.-H., Kuo, T.-H., Liaw, W., Lu, T., Kao, C.-F., & Wang, Y. (2023) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00348 · Cited by 17

Amyloid solutions: lecanemab, gantenerumab, and donanemab in the treatment of Alzheimer's disease

Ameen, T. B., Ali, U., Salma, O., Samee, M. A., Abbas, S. M. I., Kashif, S. N., Arifi, M. A., Ali, M., Khowaja, M., Ali, S. M. S., et al. (2025) · The Egyptian Journal of Neurology Psychiatry and Neurosurgery · doi:10.1186/s41983-025-00968-3 · Cited by 20

P-Glycoprotein Altered Expression in Alzheimer's Disease: Regional Anatomic Variability

Jeynes, B., & Provias, J. (2013) · Journal of Neurodegenerative Diseases · doi:10.1155/2013/257953 · Cited by 17

Role of Mitochondrial Protein Import in Age-Related Neurodegenerative and Cardiovascular Diseases

Bogorodskiy, A. O., Okhrimenko, I. S., Burkatovskii, D., Jakobs, P., Maslov, I., Gordeliy, V., Dencher, N. A., Gensch, T., Voos, W., Altschmied, J., et al. (2021) · Cells · doi:10.3390/cells10123528 · Cited by 19

Naturally Inspired Molecules as Multifunctional Agents for Alzheimer’s Disease Treatment

Rampa, A., Tarozzi, A., Mancini, F. R., Pruccoli, L., Martino, R. M. C. D., Gobbi, S., Bisi, A., Simone, A. D., Palomba, F., Zaccheroni, N., et al. (2016) · Molecules · doi:10.3390/molecules21050643 · Cited by 17

In Search of an Identity for Amyloid Plaques

Huynh, T. V., & Holtzman, D. M. (2018) · Trends in Neurosciences · doi:10.1016/j.tins.2018.06.002 · Cited by 17

Human adipose-derived stem cells reduce receptor-interacting protein 1, receptor-interacting protein 3, and mixed lineage kinase domain-like pseudokinase as necroptotic markers in rat model of Alzheimer’s disease

Shariatpanahi, M., Eftekharzadeh, M., Simorgh, S., Doshmanziari, M., & Hassanzadeh, L. (2020) · Indian Journal of Pharmacology · doi:10.4103/ijp.ijp_545_19 · Cited by 17

Down’s syndrome and Alzheimer’s disease: two sides of the same coin

Potter, H. (2007) · Future Neurology · doi:10.2217/14796708.3.1.29 · Cited by 17

Bamboo leaf extract improves spatial learning ability in a rat model with senile dementia

Liu, J., Min-ying, Z., Feng, C.-Y., Ding, H.-B., Zhan, Y., Zhao, Z., & Ding, Y. (2015) · Journal of Zhejiang University SCIENCE B · doi:10.1631/jzus.b1400249 · Cited by 17

Osteoblastic Swedish mutant APP expedites brain deficits by inducing endoplasmic reticulum stress-driven senescence

Pan, J., Sun, D., Lee, D., Xiong, L., Ren, X., Guo, H.-H., Yao, L., Lu, Y., Jung, C., & Xiong, W. (2021) · Communications Biology · doi:10.1038/s42003-021-02843-2 · Cited by 17

Comparative analysis of different brain regions using machine learning for prediction of EMCI and LMCI stages of Alzheimer’s disease

Uysal, G., & Öztürk, M. (2023) · Multimedia Tools and Applications · doi:10.1007/s11042-023-16413-7 · Cited by 16

Evolving Relevance of Neuroproteomics in Alzheimer’s Disease

Lista, S., Zetterberg, H., O’Bryant, S. E., Blennow, K., & Hampel, H. J. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-6952-4_5 · Cited by 16

Animal Research for Alzheimer Disease: Failures of Science and Ethics

Pippin, J. J., Cavanaugh, S. E., & Pistollato, F. (2019) · BRILL eBooks · doi:10.1163/9789004391192_021 · Cited by 16

Lyn Kinase Structure, Regulation, and Involvement in Neurodegenerative Diseases: A Mini Review

Weerawarna, P. M., & Richardson, T. I. (2023) · Kinases and Phosphatases · doi:10.3390/kinasesphosphatases1010004 · Cited by 16

FDG PET (and MRI) for Monitoring Immunotherapy in Alzheimer Disease

Høilund‐Carlsen, P. F., Revheim, M.-E. R., Alavi, A. A., & Barrio, J. R. (2023) · Clinical Nuclear Medicine · doi:10.1097/rlu.0000000000004710 · Cited by 16

Glucose regulates amyloid β production via AMPK

Yang, T.-T., Shih, Y.-S., Chen, Y., Kuo, Y., & Lee, C.-W. (2015) · Journal of Neural Transmission · doi:10.1007/s00702-015-1413-5 · Cited by 18

The Blood brain-barrier and its role in Alzheimer’s disease

Storck, S. E., & Pietrzik, C. U. (2018) · e-Neuroforum · doi:10.1515/nf-2018-a014 · Cited by 16

Amyloid-β expression in retrosplenial cortex of triple transgenic mice: relationship to cholinergic axonal afferents from medial septum

Robertson, R. T., Baratta, J. L., Yu, J., & LaFerla, F. M. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.09.024 · Cited by 16

AdipoRon promotes amyloid‐β clearance through enhancing autophagy via nuclear GAPDH‐induced sirtuin 1 activation in Alzheimer's disease

Sun, F., Wang, J., Meng, L., Zhou, Z., Xu, Y., Yang, M., Li, Y., Jiang, T., Liu, B., & Yan, H. (2024) · British Journal of Pharmacology · doi:10.1111/bph.16400 · Cited by 16

Exploring the Potential of Neuroproteomics in Alzheimer's Disease

Uddin, M. S., Kabir, M. T., Jakaria, M., Sobarzo‐Sánchez, E., Barreto, G. E., Perveen, A., Hafeez, A., Bin-Jumah, M. N., Abdel‐Daim, M. M., & Ashraf, G. M. (2020) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026620666200603112030 · Cited by 17

Modulation of High-Fat Diet-Induced Brain Oxidative Stress by Ferulate-Rich Germinated Brown Rice Ethyl Acetate Extract

Azmi, N. H., Ismail, N., Imam, M. U., Ooi, D. J., & Oslan, S. N. H. (2022) · Molecules · doi:10.3390/molecules27154907 · Cited by 15

APP in the Neuromuscular Junction for the Development of Sarcopenia and Alzheimer’s Disease

Wu, M., Zou, W.-J., Lee, D., Mei, L., & Xiong, W. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24097809 · Cited by 17

Synthesis and evaluation of indolinyl- and indolylphenylacetylenes as PET imaging agents for β-amyloid plaques

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Localized vs. Systematic Neurodegeneration: A Paradigm Shift in Understanding Neurodegenerative Diseases

Bayati, A., & Berman, T. (2017) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2017.00062 · Cited by 15

Computational Design of Apolipoprotein E4 Inhibitors for Alzheimer’s Disease Therapy from Traditional Chinese Medicine

Huang, H.-J., Chen, H., Lee, C.-C., & Chen, C. Y. (2014) · BioMed Research International · doi:10.1155/2014/452625 · Cited by 15

Daedalols A–C, fungal-derived BACE1 inhibitors

Sorribas, A., Jiménez, J. I., Yoshida, W. Y., & Williams, P. G. (2011) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2011.09.029 · Cited by 14

Visual reading for [18F]Florzolotau ([18F]APN-1607) tau PET imaging in clinical assessment of Alzheimer’s disease

Lin, H.-C., Lin, K., Huang, K., Chen, S.-H., Ho, T., Huang, C., Hsu, J., Chang, C., & Hsiao, I. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1148054 · Cited by 14

Gene- gene interaction between PPARG and APOE gene on late-onset Alzheimer's disease: A case- control study in Chinese han population

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The Potential Effect of Caffeine and Nicotine Co-administration against Aluminum-induced Alzheimer's disease in Rats

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Motor deficits are independent of axonopathy in an Alzheimer's disease mouse model of TgCRND8 mice

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Verteporfin is a substrate-selective γ-secretase inhibitor that binds the amyloid precursor protein transmembrane domain

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Gamma-Secretase Inhibitor Activity of a Pterocarpus erinaceus Extract

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Preamyloid Lesions and Cerebrovascular Deposits in the Mechanism of Dementia: Lessons from Non-β-Amyloid Cerebral Amyloidosis

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Impact of GSK-3β and CK-1δ on Wnt signaling pathway in alzheimer disease: A dual target approach

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Conformation states of DYRK1A affected by phosphorylation: Explorations from GaMD simulations and deep learning

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Global experience in brain amyloid imaging

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Amyloid Deposition as the Central Event in the Etiology and Pathogenesis of Alzheimer’s Disease

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The amyloid cascade hypothesis: are we poised for success or failure?

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Correspondence to Author:

Behera, S. K., Behera, R. K., Barik, M. R., & Lokhande, R. S. (2013)

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Reitz, C. (2012)

Journal of Neurochemistry special issue on Alzheimer’s disease: ‘amyloid cascade hypothesis – 20 years on’

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