Aerodynamic Assessment of Phonatory Onset in Parkinson's Disease: Evidence of Decreased Scaling of Laryngeal and Respiratory Control
Open accessAbstract
Background: Phonatory onset is important for speech and voice and may be substantially impaired in people with Parkinson's Disease (PD). However, the physiologic contributions of laryngeal and respiratory control to phonatory onset in PD are not well understood. Acoustic measurement of phonatory onset in neurological disease has been limited due to the confounding effects of dysarthria and the limited yield of physiologic detail. Objective: The purpose of this study was to test whether air flow measures would be useful to characterize respiratory and laryngeal contributions to phonatory onset, whether acoustic and air flow measures of phonatory onset were aberrant in PD, and whether deficits were significantly associated with voice severity. Methods: Twenty-one PD participants were tested and compared with 25 healthy controls. Testing included acoustic and air flow measures of phonatory onset during syllable production ([pa]) and measures of voice severity. Results: Air flow assessment was possible for all participants; acoustic assessment was only possible for 86% of PD participants. Air flow and acoustic measures revealed shorter phonatory onset times for PD participants than controls. Air flow measures also revealed that PD participants expelled less lung air volume per syllable. Aberrant timing of phonatory onset and reduced lung air volume were associated with increased voice severity. Conclusions: These findings suggest that air flow measures may be useful to assess the laryngeal and respiratory contributions to phonatory onset. These results also suggest that both respiratory and laryngeal control deficits may contribute to phonatory errors in PD, and that phonatory onset deficits are associated with voice severity.
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Insufficient laryngeal function and abnormal laryngeal somatosensory function could have contributed to the lower vocal loudness in the participants.
“Insufficient laryngeal function and abnormal laryngeal somatosensory function could have contributed to the lower vocal loudness in our participants [54, 55].”
From Comparing face-to-face and online LSVT®LOUD speech training using LSVT®Coach in patients with Parkinson’s disease: a pilot randomised controlled trial (2025) · cites this paper as [55]
The Results and Discussion link aberrant laryngeal and respiratory control in participants with Parkinson’s disease to greater voice severity, which supports a possible laryngeal contribution to voice problems. The paper does not establish that these deficits caused lower vocal loudness specifically, and it does not test whether abnormal laryngeal somatosensory function contributed to loudness. The cited passages have no page numbers in our copy. (LLM, conf=0.84)
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- Authors
- Hammer, M. J.
- Affiliations
- University of Wisconsin–Madison (US)
- Corresponding author
- Hammer, Michael J.
- Venue
- Journal of Parkinson’s Disease
- Publisher
- SAGE Publications
- Published
- 2013-01-01
- Volume
- 3
- Issue
- 2
- Pages
- 173-179
- ISSN
- 1877-7171 (ISSN-L)
- 1877-718X
- PMC
- PMC3673725
- OpenAlex
- W1568441342
- Cited by
- 21
- References
- 33
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 3 · 2021: 2 · 2020: 3 · 2019: 2 · 2018: 2 · 2017: 1 · 2015: 1 · 2014: 3
- FWCI
- 0.93
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Journal of Parkinson s Disease (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Institutes of Health (UL1TR000427)
- National Institute on Deafness and Other Communication Disorders (L30 DC010356, R03DC010900, DC010900)
- National Center for Research Resources (K12RR023268, RR025012, KL2RR025012, RR023268)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Physiology › Voice and Speech Disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Phonetics and Phonology Research
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory and Cough-Related Research
- Keywords
- Parkinson's disease, air flow measurement, laryngeal control, respiratory control, dysarthria
- MeSH terms
- Aged, Analysis of Variance, Diagnosis, Computer-Assisted, Female, Fourier Analysis, Humans, Laryngeal Diseases, Lung Volume Measurements, Male, Neurologic Examination, Parkinson Disease, Phonation, Respiration Disorders, Severity of Illness Index, Speech Production Measurement, Time Factors
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