The DOI matches its Crossref record; 123 of the 123 references it cites were found in a registry or an index.
Parkinson’s Disease in Women and Men: What’s the Difference?
Open accessAbstract
Increasing evidence points to biological sex as an important factor in the development and phenotypical expression of Parkinson’s disease (PD). Risk of developing PD is twice as high in men than women, but women have a higher mortality rate and faster progression of the disease. Moreover, motor and nonmotor symptoms, response to treatments and disease risk factors differ between women and men. Altogether, sex-related differences in PD support the idea that disease development might involve distinct pathogenic mechanisms (or the same mechanism but in a different way) in male and female patients. This review summarizes the most recent knowledge concerning differences between women and men in PD clinical features, risk factors, response to treatments and mechanisms underlying the disease pathophysiology. Unraveling how the pathology differently affect the two sexes might allow the development of tailored interventions and the design of innovative programs that meet the distinct needs of men and women, improving patient care.
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Cites
Impulse Control Disorders in Parkinson Disease: A Cross-Sectional Study of 3090 Patients
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Parkinson disease: from pathology to molecular disease mechanisms
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Sex-specific features of microglia from adult mice
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The Incidence of Parkinson's Disease: A Systematic Review and Meta-Analysis
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Microglia Are Essential to Masculinization of Brain and Behavior
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Cited by
Incidence of Parkinson disease in North America
Willis, A. W., Roberts, E., Beck, J. C., Fiske, B., Ross, W., Savica, R., Van Den Eeden, S. K., Tanner, C. M., Marras, C., on behalf of the Parkinson’s Foundation P4 Group, et al. (2022) · npj Parkinson's Disease · doi:10.1038/s41531-022-00410-y · Cited by 341
Dentamaro, V., Impedovo, D., Musti, L., Pirlo, G., & Taurisano, P. (2024) · Scientific Reports · doi:10.1038/s41598-024-70165-4 · Cited by 116
Kawahata, I., & Fukunaga, K. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21113779 · Cited by 71
Amin, R., Quispe, C., Docea, A. O., Ydyrys, A., Kulbayeva, M., Durna Daştan, S., Calina, D., & Sharifi-Rad, J. (2022) · Neurochemistry International · doi:10.1016/j.neuint.2022.105376 · Cited by 74
Tauroursodeoxycholic acid (TUDCA) is neuroprotective in a chronic mouse model of Parkinson’s disease
Cuevas, E., Burks, S., Raymick, J., Robinson, B., Gómez-Crisóstomo, N. P., Escudero-Lourdes, C., Lopez, A. G. G., Chigurupati, S., Hanig, J., Ferguson, S. A., et al. (2022) · Nutritional Neuroscience · doi:10.1080/1028415x.2020.1859729 · Cited by 57
Metadata
- Authors
- Cerri, S., Mus, L., & Blandini, F.
- Venue
- Journal of Parkinson’s Disease
- Publisher
- SAGE Publications
- Published
- 2019-07-04
- Volume
- 9
- Issue
- 3
- Pages
- 501-515
- ISSN
- 1877-7171 (ISSN-L)
- 1877-718X
- OpenAlex
- W2953791151
- Cited by
- 800
- References
- 123
- FWCI
- 29.29
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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