The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Management of Epstein-Barr Virus infections and post-transplant lymphoproliferative disorders in patients after allogeneic hematopoietic stem cell transplantation: Sixth European Conference on Infections in Leukemia (ECIL-6) guidelines
Open accessAbstract
Epstein-Barr virus-related post-transplant lymphoproliferative disorders are recognized as a significant cause of morbidity and mortality in patients undergoing hematopoietic stem cell transplantation. To better define current understanding of post-transplant lymphoproliferative disorders in stem cell transplant patients, and to improve its diagnosis and management, a working group of the Sixth European Conference on Infections in Leukemia 2015 reviewed the literature, graded the available quality of evidence, and developed evidence-based recommendations for diagnosis, prevention, prophylaxis and therapy of post-transplant lymphoproliferative disorders exclusively in the stem cell transplant setting. The key elements in diagnosis include non-invasive and invasive methods. The former are based on quantitative viral load measurement and imaging with positron emission tomography; the latter with tissue biopsy for histopathology and detection of Epstein-Barr virus. The diagnosis of post-transplant lymphoproliferative disorder can be established on a proven or probable level. Therapeutic strategies include prophylaxis, preemptive therapy and targeted therapy. Rituximab, reduction of immunosuppression and Epstein-Barr virus-specific cytotoxic T-cell therapy are recommended as first-line therapy, whilst unselected donor lymphocyte infusions or chemotherapy are options as second-line therapy; other methods including antiviral drugs are discouraged.
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Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions
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Cited by
Post-Transplantation Lymphoproliferative Disorders in Adults
Dierickx, D., & Habermann, T. M. (2018) · New England Journal of Medicine · doi:10.1056/nejmra1702693 · Cited by 481
Metadata
- Authors
- Styczynski, J., van der Velden, W., Fox, C. P., Engelhard, D., de la Camara, R., Cordonnier, C., Ljungman, P., & on behalf of the Sixth European Conference on Infections in Leukemia, A. J. V. O. T. I. D. W. P. O. T. E. S. O. B. A. M. T. (.-I.
- Venue
- Haematologica
- Published
- 2016-06-30
- Volume
- 101
- Issue
- 7
- Pages
- 803-811
- ISSN
- 0390-6078 (ISSN-L)
- 1592-8721
- OpenAlex
- W2465355173
- Cited by
- 408
- References
- 37
- FWCI
- 14.99
- Type
- journal article
- Language
- en
- Open access
- gold
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- Styczynski, J., van der Velden, W., Fox, C. P., Engelhard, D., de la Camara, R., Cordonnier, C., Ljungman, P., & on behalf of the Sixth European Conference on Infections in Leukemia, A. J. V. O. T. I. D. W. P. O. T. E. S. O. B. A. M. T. (.-I. (2016). Management of Epstein-Barr Virus infections and post-transplant lymphoproliferative disorders in patients after allogeneic hematopoietic stem cell transplantation: Sixth European Conference on Infections in Leukemia (ECIL-6) guidelines. Haematologica. https://doi.org/10.3324/haematol.2016.144428
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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