The origin of 7α-hydroxy-dehydroepiandrosterone and its physiological role: a history of discoveries

Dehydroepiandrosterone (DHEA): a fountain of youth?

Baulieu, É.-É. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.9.8784058 · Cited by 367 · see citing works

Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7α-hydroxy dehydroepiandrosterone and 7α-hydroxy pregnenolone

Rose, K. A., Stapleton, G., Dott, K., Kiény, M. P., Best, R., Schwarz, M., Russell, D. W., Björkhem, I., Seckl, J. R., & Lathe, R. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.10.4925 · Cited by 221 · see citing works

Dehydroepiandrosterone: A neuroactive steroid

Stárka, L., Dušková, M., & Hill, M. (2014) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2014.03.008 · Cited by 170 · see citing works

Astrocytes and neurosteroids: metabolism of pregnenolone and dehydroepiandrosterone. Regulation by cell density.

Akwa, Y., Sananès, N., Gouézou, M., Röbel, P., Baulieu, E. E., & Goascogne, C. L. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.121.1.135 · Cited by 164 · see citing works

Neurosteroid metabolism. 7α-Hydroxylation of dehydroepiandrosterone and pregnenolone by rat brain microsomes

Akwa, Y., Morfin, R. F., Röbel, P., & Baulieu, E. E. (1992) · Biochemical Journal · doi:10.1042/bj2880959 · Cited by 163 · see citing works

A Novel Cytochrome P450 Expressed Primarily in Brain

Stapleton, G., Steel, M., Richardson, M., Mason, J. O., Rose, K. A., Morris, R., & Lathe, R. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.50.29739 · Cited by 153 · see citing works

Pregnenolone and dehydroepiandrosterone as precursors of native 7-hydroxylated metabolites which increase the immune response in mice

Morfin, R. F., & Courchay, G. (1994) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(94)90176-7 · Cited by 129 · see citing works

Dehydroepiandrosterone 7-hydroxylase cyp7b: predominant expression in primate hippocampus and reduced expression in alzheimer's disease☆

Yau, J. L. W., Rasmuson, S., Andrew, R., Graham, M., Noble, J., Olsson, T., Fuchs, E., Lathe, R., & Seckl, J. R. (2003) · Neuroscience · doi:10.1016/s0306-4522(03)00438-x · Cited by 118 · see citing works

Steroid and sterol 7-hydroxylation: ancient pathways.

Lathe, R. (2002) · Steroids · doi:10.1016/s0039-128x(02)00044-2 · Cited by 104 · see citing works

Steroid metabolome in plasma from the umbilical artery, umbilical vein, maternal cubital vein and in amniotic fluid in normal and preterm labor

Hill, M., Pařı́zek, A., Kancheva, R. L., Dušková, M., Velíková, M., Kříž, L., Klímková, M., Pašková, A., Žižka, Z., Matucha, P., et al. (2009) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2009.10.012 · Cited by 102 · see citing works

Neurosteroid 7-hydroxylation products in the brain

Morfin, R. F., & Stárka, L. (2001) · International review of neurobiology · doi:10.1016/s0074-7742(01)46059-4 · Cited by 99 · see citing works

Neurosteroids: Cerebrospinal Fluid Levels for Alzheimer’s Disease and Vascular Dementia Diagnostics

Kim, S.-B., Hill, M., Kwak, Y. T., Hampl, R., Jo, D.-H., & Morfin, R. F. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030646 · Cited by 96 · see citing works

In vitro metabolism of dehydroepiandrosterone (DHEA) to 7α-hydroxy-DHEA and Δ5-androstene-3β,17β-diol in specific regions of the aging brain from Alzheimer’s and non-demented patients

Weill‐Engerer, S., David, J.-P., Sazdovitch, V., Lière, P., Schumacher, M., Delacourte, A., Baulieu, É.-É., & Akwa, Y. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02288-1 · Cited by 91 · see citing works

Neurosteroid Hydroxylase CYP7B

Rose, K. A., Allan, A. K., Gauldie, S. D., Stapleton, G., Dobbie, L., Dott, K., Martin, C., Wang, L., Hedlund, E., Seckl, J. R., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m011564200 · Cited by 90 · see citing works

Neuroactive steroids in periphery and cerebrospinal fluid

Kancheva, R. L., Hill, M., Novák, Z., Chrastina, J., Kancheva, L., & Stárka, L. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.05.054 · Cited by 82 · see citing works

Dehydroepiandrosterone 7α-hydroxylation in human tissues: Possible interference with type 1 11β-hydroxysteroid dehydrogenase-mediated processes

Hennebert, O., Chalbot, S., Alran, S., & Morfin, R. (2007) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2007.03.026 · Cited by 79 · see citing works

7‐Hydroxylated epiandrosterone (7‐OH‐EPIA) reduces ischaemia‐induced neuronal damage both in vivo and in vitro

Pringle, A. K., Schmidt, W., Deans, J. K., Wülfert, E., Reymann, K. G., & Sundström, L. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02734.x · Cited by 76 · see citing works

Ergosteroids: induction of thermogenic enzymes in liver of rats treated with steroids derived from dehydroepiandrosterone.

Lardy, H. A., Partridge, B., Kneer, N. M., & Wei, Y. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.14.6617 · Cited by 76 · see citing works

Glucocorticoids inhibit interconversion of 7-hydroxy and 7-oxo metabolites of dehydroepiandrosterone: a role for 11β-hydroxysteroid dehydrogenases?

Robinzon, B., Michael, K. K., Ripp, S. L., Winters, S. J., & Prough, R. A. (2003) · Archives of Biochemistry and Biophysics · doi:10.1016/s0003-9861(03)00056-0 · Cited by 70 · see citing works

Anti-proliferative action of endogenous dehydroepiandrosterone metabolites on human cancer cell lines

Yoshida, S., Honda, A., Matsuzaki, Y., Fukushima, S., Tanaka, N., Takagiwa, A., Fujimoto, Y., Miyazaki, H., & Salen, G. (2002) · Steroids · doi:10.1016/s0039-128x(02)00117-4 · Cited by 64 · see citing works

Peripheral neuroactive steroids may be as good as the steroids in the cerebrospinal fluid for the diagnostics of CNS disturbances

Kancheva, R. L., Hill, M., Novák, Z., Chrastina, J., Velíková, M., Kancheva, L., Říha, I., & Stárka, L. (2009) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2009.12.006 · Cited by 61 · see citing works

Studies of the enzyme complex responsible for pregnenolone and dehydroepiandrosterone 7α-hydroxylation in mouse tissues

Doostzadeh, J., & Morfin, R. (1996) · Steroids · doi:10.1016/s0039-128x(96)00122-5 · Cited by 60 · see citing works

Characterization of the dehydroepiandrosterone (DHEA) metabolism via oxysterol 7α‐hydroxylase and 17‐ketosteroid reductase activity in the human brain

Steckelbroeck, S., Watzka, M., Lütjohann, D., Makiola, P., Nassen, A., Hans, V., Clusmann, H., Reissinger, A., Ludwig, M. Z., Siekmann, L., et al. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.01187.x · Cited by 57 · see citing works

Determination of seven selected neuro- and immunomodulatory steroids in human cerebrospinal fluid and plasma using LC-MS/MS

Kolátorová, L., Vítků, J., Chlupáčová, T., Mohapl, M., & Hampl, R. (2015) · Steroids · doi:10.1016/j.steroids.2015.01.019 · Cited by 56 · see citing works

Metabolism of dehydroepiandrosterone by rat hippocampal cells in culture: possible role of aromatization and 7-hydroxylation in neuroprotection

Jellinck, P. H., Lee, S. H., & McEwen, B. S. (2001) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(01)00106-6 · Cited by 55 · see citing works

The native anti-glucocorticoid paradigm

Muller, C., Hennebert, O., & Morfin, R. F. (2006) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2006.03.001 · Cited by 53 · see citing works

The 7α-hydroxysteroids produced in human tonsils enhance the immune response to tetanus toxoid and Bordetella pertussis antigens

Lafaye, P. J., Chmielewski, V., Nato, F., Mazié, J. C., & Morfin, R. F. (1999) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(99)00124-5 · Cited by 51 · see citing works

Ergosteroids

Marwah, A. K., Marwah, P., & Lardy, H. A. (2002) · Journal of Chromatography B · doi:10.1016/s1570-0232(01)00570-0 · Cited by 50 · see citing works

Metabolism of dehydroepiandrosterone by cultured human adipose stromal cells: Identification of 7α-hydroxydehydroepiandrosterone as a major metabolite using high performance liquid chromatography and mass spectrometry

Khalil, M. W., Strutt, B. J., Vachon, D., & KILLINGER, D. W. (1993) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(93)90186-z · Cited by 49 · see citing works

Transformation In Vitro of [4-14C]-Dehydroepiandros-Terone into 7-Oxygenated Derivatives by Normal Human Male and Female Skin Tissue*

Faredin, I., Fazekas, A. G., Tóth, I., Kókai, K., & Julesz, M. (1969) · Journal of Investigative Dermatology · doi:10.1038/jid.1969.61 · Cited by 48 · see citing works

Isolation and Characterization of 3β-Hydroxy-Δ5-Steroids in Adrenal Carcinoma

Okada, M., Fukushima, D. K., & Gallagher, T. F. (1959) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)69908-9 · Cited by 48 · see citing works

7α‐Hydroxy‐Dehydroepiandrosterone and Immune Response

Morfin, R. F., Lafaye, P. J., Cotillon, A.-C., Nato, F., Chmielewski, V., & Pompon, D. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb05464.x · Cited by 47 · see citing works

Neuro- and immunomodulatory steroids and other biochemical markers in drug-naive schizophrenia patients and the effect of treatment with atypical antipsychotics.

Bičı́ková, M., Hampl, R., Hill, M., Řı́pová, D., Mohr, P., & Putz, Z. (2011) · PubMed · Cited by 46 · see citing works

Dexamethasone‐induced apoptosis of mouse thymocytes: Prevention by native 7α‐hydroxysteroids

Chmielewski, V., Drupt, F., & Morfin, R. F. (2000) · Immunology and Cell Biology · doi:10.1046/j.1440-1711.2000.00905.x · Cited by 46 · see citing works

Immunoassay of 7-hydroxysteroids: 2. Radioimmunoassay of 7α-hydroxy-dehydroepiandrosterone

Lapčı́k, O., Hampl, R., Hill, M., & Stárka, L. (1999) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(99)00145-4 · Cited by 46 · see citing works

Synthesis of 7α-hydroxy-dehydroepiandrosterone and 7β-hydroxy-dehydroepiandrosterone

Li, H., Liu, H., Ge, W.-Z., Huang, L., & Shan, L. (2005) · Steroids · doi:10.1016/j.steroids.2005.07.006 · Cited by 45 · see citing works

cyp7b1 catalyses the 7α-hydroxylation of dehydroepiandrosterone and25-hydroxycholesterol in rat prostate

Martin, C., Bean, R., Rose, K. A., Habib, F. K., & Seckl, J. R. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3550509 · Cited by 42 · see citing works

7-Hydroxylation of dehydroepiandrosterone by rat-liver homogenate

Stárka, L., & Kůtová, J. (1962) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(62)90528-0 · Cited by 41 · see citing works

The human cytochrome P4507B1: catalytic activity studies

Kim, S.-B., Chalbot, S., Pompon, D., Jo, D.-H., & Morfin, R. F. (2004) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2004.09.005 · Cited by 41 · see citing works

HUMAN LIVER S9 FRACTIONS: METABOLISM OF DEHYDROEPIANDROSTERONE, EPIANDROSTERONE, AND RELATED 7-HYDROXYLATED DERIVATIVES

Chalbot, S., & Morfin, R. F. (2005) · Drug Metabolism and Disposition · doi:10.1124/dmd.104.003004 · Cited by 40 · see citing works

Immunoassay of 7-hydroxysteroids: 1. Radioimmunoassay of 7β-hydroxy dehydroepiandrosterone

Lapčı́k, O., Hampl, R., Hill, M., Bičı́ková, M., & Stárka, L. (1998) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(98)00136-8 · Cited by 40 · see citing works

Antioxidant effects of dehydroepiandrosterone and 7α-hydroxy-dehydroepiandrosterone in the rat colon, intestine and liver

Pélissier, M. A., Trap, C., Malewiak, M. I., & Morfin, R. F. (2004) · Steroids · doi:10.1016/j.steroids.2003.12.006 · Cited by 40 · see citing works

Reaktion der Steroide mit Tert-butylperbenzoat I. Über die 7-Acyloxylierung Δ5-ungesättigter Steroide

Stárka, L. (1961) · Collection of Czechoslovak Chemical Communications · doi:10.1135/cccc19612452 · Cited by 39 · see citing works

Dehydroepiandrosterone (DHEA) metabolism in Saccharomyces cerevisiae expressing mammalian steroid hydroxylase CYP7B: Ayr1p and Fox2p display 17β‐hydroxysteroid dehydrogenase activity

Vico, P. Á. R., Cauet, G., Rose, K. A., Lathe, R., & Degryse, E. (2002) · Yeast · doi:10.1002/yea.882 · Cited by 35 · see citing works

7-HYDROXYLATION OF DEHYDROEPIANDROSTERONE IN HUMAN FOETAL LIVER, ADRENALS AND CHORION IN VITRO

Šulcová, J., Capková, A., Jirásek, J. E., & Stárka, L. (1968) · European Journal of Endocrinology · doi:10.1530/acta.0.0590001 · Cited by 35 · see citing works

7α- and 7β-hydroxy-epiandrosterone as substrates and inhibitors for the human 11β-hydroxysteroid dehydrogenase type 1

Hennebert, O., Pernelle, C., Ferroud, C., & Morfin, R. F. (2007) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2006.11.021 · Cited by 34 · see citing works

Dehydroepiandrosterone 7α‐ and 7β‐Hydroxylation in Mouse Brain Microsomes. Effects of Cytochrome P450 Inhibitors and Structure‐Specific Inhibition by Steroid Hormones

Doostzadeh, J., Cotillon, A.-C., & Morfin, R. F. (1997) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1997.00661.x · Cited by 34 · see citing works

Characterisation of microsomal dehydroepiandrosterone 7-hydroxylase from rat liver

Šulcová, J., & Stárka, L. (1968) · Steroids · doi:10.1016/s0039-128x(68)80084-4 · Cited by 33 · see citing works

Dehydroepiandrosterone Metabolites and their Interactions in Humans

Chalbot, S., & Morfin, R. F. (2006) · Drug metabolism and drug interactions · doi:10.1515/dmdi.2006.22.1.1 · Cited by 33 · see citing works

Metabolism of dehydroepiandrosterone by rodent brain cell lines: Relationship between 7-hydroxylation and aromatization

Jellinck, P. H., Croft, G. F., McEwen, B. S., Gottfried‐Blackmore, A., Jones, G., Byford, V., & Bulloch, K. (2005) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2004.11.008 · Cited by 33 · see citing works

Increased Total 7α-Hydroxy-Dehydroepiandrosterone in Serum of Patients With Alzheimer's Disease

Attal-Khémis, S., Dalmeyda, V., Michot, J., Roudier, M., & Morfin, R. (1998) · The Journals of Gerontology Series A · doi:10.1093/gerona/53a.2.b125 · Cited by 33 · see citing works

Central Administration of a Cytochrome P450-7B Product 7α-Hydroxypregnenolone Improves Spatial Memory Retention in Cognitively Impaired Aged Rats

Yau, J. L. W., Noble, J., Graham, M. K., & Seckl, J. R. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3189-06.2006 · Cited by 30 · see citing works

Inhibition studies of dehydroepiandrosterone 7α- and 7β-hydroxylation in mouse liver microsomes

Doostzadeh, J., Cotillon, A.-C., Benalychérif, A., & Morfin, R. F. (1998) · Steroids · doi:10.1016/s0039-128x(98)00071-3 · Cited by 30 · see citing works

Dehydroepiandrosterone and its 7-hydroxylated metabolites do not interfere with the transactivation and cellular trafficking of the glucocorticoid receptor

Muller, C., Cluzeaud, F., Pinon, G. M., Rafestin-Oblin, M. E., & Morfin, R. F. (2004) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2004.10.014 · Cited by 30 · see citing works

7β-OH-DHEA counteracts dexamethasone induced suppression of primary immune response in murine spleenocytes

Sterzl, I., Hampl, R., Šterzl, J., Votruba, J., & Stárka, L. (1999) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(99)00134-x · Cited by 28 · see citing works

Die harnausscheidung von 7-hydroxy-dehydroepiandrosteronsulfat

Stárka, L., Šulcová, J., & Silink, K. (1962) · Clinica Chimica Acta · doi:10.1016/0009-8981(62)90029-3 · Cited by 28 · see citing works

7-Hydroxydehydroepiandrosterone--a natural antiglucocorticoid and a candidate for steroid replacement therapy?

Hampl, R., Lapcík, O., Hill, M., Klak, J., Kasal, A., Nováček, A., Sterzl, I., Šterzl, J., & Stárka, L. (2000) · PubMed · Cited by 27 · see citing works

Epimerase activity of the human 11β-hydroxysteroid dehydrogenase type 1 on 7-hydroxylated C19-steroids

Hennebert, O., Montes, M., Favre-Reguillon, A., Chermette, H., Ferroud, C., & Morfin, R. (2009) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2008.12.015 · Cited by 27 · see citing works

Plasma levels of 7-hydroxylated dehydroepiandrosterone (DHEA) metabolites and selected amino-thiols as discriminatory tools of Alzheimer's disease and vascular dementia

Bičı́ková, M., Řı́pová, D., Hill, M., Jirák, R., Havlı́ková, H., Tallová, J., & Hampl, R. (2004) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2004.088 · Cited by 27 · see citing works

MINIREVIEW 7-HYDROXYLATED DERIVATIVES OF DEHYDROEPIANDROSTERONE: WHAT ARE THEY GOOD FOR?

Hampl, R., Morfin, R., & Stárka, L. (1997) · PubMed · Cited by 27 · see citing works

A radioimmunoassay for 7α-hydroxy dehydroepiandrosterone in human plasma

Skinner, S. J. M., Tobler, C. J. P., & Couch, R. A. F. (1977) · Steroids · doi:10.1016/0039-128x(77)90023-x · Cited by 26 · see citing works

Steroid hormones in prediction of normal pressure hydrocephalus

Kolátorová, L., Hill, M., Mohapl, M., Vítků, J., & Hampl, R. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2015.05.004 · Cited by 25 · see citing works

The 7β-hydroxylation of 3β-hydroxyandrost-5-en-17-one by hepatic microsomes

Heinrichs, W. L., Mushen, R. L., & Colás, A. E. (1967) · Steroids · doi:10.1016/0039-128x(67)90086-4 · Cited by 25 · see citing works

7-Hydroxydehydroepiandrosterone epimers in human serum and saliva

Hill, M., Lapčı́k, O., Havlı́ková, H., Morfin, R. F., & Hampl, R. (2001) · Journal of Chromatography A · doi:10.1016/s0021-9673(01)01106-2 · Cited by 24 · see citing works

The in vitro synthesis of 7-hydroxy dehydroepiandrosterone by human mammary tissues

Couch, R. A. F., Skinner, S. J. M., Tobler, C. J. P., & Doouss, T. W. (1975) · Steroids · doi:10.1016/0039-128x(75)90002-1 · Cited by 23 · see citing works

Neuroimmunomodulatory steroids in Alzheimer dementia

Hampl, R., & Bičı́ková, M. (2010) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2010.02.007 · Cited by 23 · see citing works

7-Hydroxydehydroepiandrosterone epimers in the life span

Hampl, R., Hill, M., & Stárka, L. (2001) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(01)00108-x · Cited by 22 · see citing works

Immunohistochemical detection of the human cytochrome P4507B1: production of a monoclonal antibody after cDNA immunization

Trap, C., Nato, F., Chalbot, S., Kim, S.-B., Lafaye, P. J., & Morfin, R. F. (2004) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2004.09.019 · Cited by 22 · see citing works

Neurosteroids: Metabolism in human intestine microsomes

Chalbot, S., & Morfin, R. F. (2005) · Steroids · doi:10.1016/j.steroids.2004.12.004 · Cited by 21 · see citing works

Simultaneous determination of dehydroepiandrosterone and its 7-oxygenated metabolites in human serum by high-resolution gas chromatography–mass spectrometry

Matsuzaki, Y., Yoshida, S., Honda, A., Miyazaki, T., Tanaka, N., Takagiwa, A., Fujimoto, Y., & Miyazaki, H. (2004) · Steroids · doi:10.1016/j.steroids.2004.08.003 · Cited by 21 · see citing works

The selective stimulation, inhibition, and physicochemical alteration of the 7- and 16α-hydroxylases of 3β-hydroxyandrost-5-en-17-one and drug-metabolizing enzymes in hepatic microsomal fractions

Heinrichs, W. L., & Colás, A. E. (1968) · Biochemistry · doi:10.1021/bi00846a033 · Cited by 21 · see citing works

Preliminary evidence of altered steroidogenesis in women with Alzheimer’s disease: Have the patients “OLDER” adrenal zona reticularis?

Vaňková, M., Hill, M., Velíková, M., Včelák, J., Vacínová, G., Dvořáková, K., Lukášová, P., Vejražková, D., Rusina, R., Holmerová, I., et al. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2015.12.011 · Cited by 21 · see citing works

cyp7b1 catalyses the 7α-hydroxylation of dehydroepiandrosterone and25-hydroxycholesterol in rat prostate

Martin, C., Bean, R., Rose, K. A., et al. (2001) · Biochemical Journal · doi:10.1042/bj3550509 · Cited by 21 · see citing works

Ontogeny of the neurosteroid enzyme Cyp7b in the mouse

Bean, R., Seckl, J. R., Lathe, R., & Martin, C. (2001) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(00)00443-3 · Cited by 20 · see citing works

Effects of CYP7B1-mediated catalysis on estrogen receptor activation

Pettersson, H. I., Lundqvist, J., & Norlin, M. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2010.05.011 · Cited by 19 · see citing works

Immunomodulatory 7-hydroxylated metabolites of dehydroepiandrosterone are present in human semen

Hampl, R., Hill, M., Sterzl, I., & Stárka, L. (2000) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(00)00175-8 · Cited by 19 · see citing works

The 7-hydroxylation of dehydroepiandrosterone in rat brain

Li, A., & Bigelow, J. C. (2010) · Steroids · doi:10.1016/j.steroids.2010.02.003 · Cited by 19 · see citing works

The relationship of plasma 7α-hydroxy dehydroepiandrosterone to disease stage and adrenal androgens in breast cancer patients

Skinner, S. J. M., Couch, R. A. F., Thambyah, S., Dobbs, R. J., Jordan, S. M., Mason, B., & Kay, R. G. (1980) · European Journal of Cancer (1965) · doi:10.1016/0014-2964(80)90154-1 · Cited by 19 · see citing works

Tumour necrosis factor-α stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-κB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b

Dulos, J., Kaptein, A., Kavelaars, A., Heijnen, C. J., & Boots, A. M. H. (2005) · Arthritis Research & Therapy · doi:10.1186/ar1819 · Cited by 19 · see citing works

Simultaneous determination of dehydroepiandrosterone, its 7-hydroxylated metabolites, and their sulfates in rat brain tissues

Kazihnítková, H., Tejkalová, H., Benešová, O., Bičı́ková, M., Hill, M., & Hampl, R. (2004) · Steroids · doi:10.1016/j.steroids.2004.06.002 · Cited by 17 · see citing works

Studies on the Mechanism of Antiglucocorticoid Action of 7α-Hydroxydehydroepiandrosterone

Stárka, L., Hill, M., Hampl, R., Malewiak, M. I., Benalychérif, A., Morfin, R. F., Kolena, J., & Scsuková, S. (1998) · Collection of Czechoslovak Chemical Communications · doi:10.1135/cccc19981683 · Cited by 16 · see citing works

Change of 7α-hydroxy-dehydroepiandrosterone levels in serum of mice treated by cytochrome P450-modifying agents

Attal-Khémis, S., Dalmeyda, V., & Morfin, R. F. (1998) · Life Sciences · doi:10.1016/s0024-3205(98)00421-4 · Cited by 16 · see citing works

7?-Hydroxylierung von Dehydroepiandrosteron in menschlicher Nebennierenrinde und Leber

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5α-Androstane-3β,7α,17β-triol and 5α-androstane-3β,7β,17β-triol as substrates for the human 11β-hydroxysteroid dehydrogenase type 1

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