Dehydroepiandrosterone 7α-hydroxylation in human tissues: Possible interference with type 1 11β-hydroxysteroid dehydrogenase-mediated processes

Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood

ORENTREICH, N., BRIND, J. L., RIZER, R. L., & VOGELMAN, J. H. (1984) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-59-3-551 · Cited by 1,349 · see citing works

Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress

Slominski, A., Wortsman, J., Luger, T., Paus, R., & Solomon, S. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.3.979 · Cited by 776 · see citing works

Neuroendocrinology of the Skin1

Slominski, A., & Wortsman, J. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.5.0410 · Cited by 727 · see citing works

Minireview: 11β-Hydroxysteroid Dehydrogenase Type 1— A Tissue-Specific Amplifier of Glucocorticoid Action1

Seckl, J. R., & Walker, B. R. (2001) · Endocrinology · doi:10.1210/endo.142.4.8114 · Cited by 714 · see citing works

Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue.

Baulieu, E.-E., Thomas, G., Legrain, S., Lahlou, N., Roger, M., Debuire, B., Faucounau, V., Girard, L., Hervy, M.-P., Latour, F., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.8.4279 · Cited by 577 · see citing works

Neuroendocrinology of the Skin

Slominski, A. T. (2000) · Endocrine Reviews · doi:10.1210/er.21.5.457 · Cited by 503 · see citing works

The Measurement of Pyridine Nucleotides by Enzymatic Cycling

Lowry, O. H., Passonneau, J. V., Schulz, D. W., & Rock, M. K. (1961) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)61729-1 · Cited by 494 · see citing works

Anti-glucocorticoid effects of dehydroepiandrosterone (DHEA).

Kalimi, M., Shafagoj, Y., Loria, R., Padgett, D., & Regelson, W. (1994) · Molecular and Cellular Biochemistry · doi:10.1007/bf00925945 · Cited by 328 · see citing works

Age and sex related differences in serum levels of unconjugated dehydroepiandrosterone and its sulphate in normal subjects

Šulcová, J., Hill, M., Hampl, R., & Stárka, L. (1997) · Journal of Endocrinology · doi:10.1677/joe.0.1540057 · Cited by 327 · see citing works

Human skin is a steroidogenic tissue: steroidogenic enzymes and cofactors are expressed in epidermis, normal sebocytes, and an immortalized sebocyte cell line (SEB-1)

Thiboutot, D., Gilliland, K., Cong, Z., Jabara, S., McAllister, J. M., Sivarajah, A., & Clawson, G. (2003) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2003.12244.x · Cited by 301 · see citing works

Corticotropin-releasing hormone: An autocrine hormone that promotes lipogenesis in human sebocytes

Zouboulis, C. C., Seltmann, H., Hiroi, N., Chen, W., Young, M., Oeff, M., Scherbaum, W. A., Orfanos, C. E., McCann, S. M., & Bornstein, S. R. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.102180999 · Cited by 290 · see citing works

Cutaneous androgen metabolism: basic research and clinical perspectives

Chen, W., Thiboutot, D., & Zouboulis, C. C. (2002) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2002.00613.x · Cited by 273 · see citing works

Differentiation of Adipose Stromal Cells: The Roles of Glucocorticoids and 11β-Hydroxysteroid Dehydrogenase*

Bujalska, I. J., Kumar, S., Hewison, M., & Stewart, P. M. (1999) · Endocrinology · doi:10.1210/endo.140.7.6868 · Cited by 254 · see citing works

CRH stimulation of corticosteroids production in melanocytes is mediated by ACTH

Slominski, A., Zbytek, B., Szczesniewski, A., Semak, I., Kaminski, J., Sweatman, T., & Wortsman, J. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00519.2004 · Cited by 211 · see citing works

Immunohistochemical Localization of Type 1 11β-Hydroxysteroid Dehydrogenase in Human Tissues1

Ricketts, M., Verhaeg, J. M., Bujalska, I. J., Howie, A. J., Rainey, W. E., & Stewart, P. M. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.4.4706 · Cited by 197 · see citing works

Human skin: an independent peripheral endocrine organ

Zouboulis, C. C. (2000) · Hormone Research in Paediatrics · doi:10.1159/000053265 · Cited by 183 · see citing works

Minireview: 11 -Hydroxysteroid Dehydrogenase Type 1-- A Tissue-Specific Amplifier of Glucocorticoid Action

Seckl, J. R. (2001) · Endocrinology · doi:10.1210/en.142.4.1371 · Cited by 172 · see citing works

Expression Profiling of Human Sulfotransferase and Sulfatase Gene Superfamilies in Epithelial Tissues and Cultured Cells

Dooley, T. P., Haldeman‐Cahill, R., Joiner, J., & Wilborn, T. W. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3643 · Cited by 144 · see citing works

CRH stimulates POMC activity and corticosterone production in dermal fibroblasts

Slominski, A., Zbytek, B., Semak, I., Sweatman, T., & Wortsman, J. (2005) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2005.01.014 · Cited by 143 · see citing works

Intracrinology and The Skin

Labrie, F., Luu-The, V., Labrie, C., Pelletier, G., & El-Alfy, M. (2000) · Hormone Research in Paediatrics · doi:10.1159/000053264 · Cited by 128 · see citing works

Structure and functions of human oxysterol 7α-hydroxylase cDNAs and gene CYP7B1

Wu, Z. L., Martin, K. O., Javitt, N. B., & Chiang, J. Y. L. (1999) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32094-0 · Cited by 128 · see citing works

Regulation of 1lβ-Hydroxysteroid Dehydrogenase Activity in Human Skin Fibroblasts: Enzymatic Modulation of Glucocorticoid Action*

Hammami, M. M., & Siiteri, P. K. (1991) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-73-2-326 · Cited by 124 · see citing works

Neurosteroid 7-hydroxylation products in the brain

Morfin, R. F., & Stárka, L. (2001) · International review of neurobiology · doi:10.1016/s0074-7742(01)46059-4 · Cited by 99 · see citing works

Age-related changes of the adrenal secretory pattern: possible role in pathological brain aging

Ferrari, E., Casarotti, D., Muzzoni, B., Albertelli, N., Cravello, L., Fioravanti, M., Solerte, S. B., & Magri, F. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00133-3 · Cited by 97 · see citing works

Inter-conversion of 7α- and 7β-hydroxy-dehydroepiandrosterone by the human 11β-hydroxysteroid dehydrogenase type 1

Muller, C., Pompon, D., Urban, P., & Morfin, R. (2006) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2005.12.001 · Cited by 77 · see citing works

Differentiation of Adipose Stromal Cells: The Roles of Glucocorticoids and 11 -Hydroxysteroid Dehydrogenase

Bujalska, I. J. (1999) · Endocrinology · doi:10.1210/en.140.7.3188 · Cited by 73 · see citing works

Immunohistochemical Localization of Type 1 11 -Hydroxysteroid Dehydrogenase in Human Tissues

Ricketts, M. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.83.4.1325 · Cited by 71 · see citing works

Glucocorticoids inhibit interconversion of 7-hydroxy and 7-oxo metabolites of dehydroepiandrosterone: a role for 11β-hydroxysteroid dehydrogenases?

Robinzon, B., Michael, K. K., Ripp, S. L., Winters, S. J., & Prough, R. A. (2003) · Archives of Biochemistry and Biophysics · doi:10.1016/s0003-9861(03)00056-0 · Cited by 70 · see citing works

Prominent sex steroid metabolism in human lymphocytes

Zhou, Z., Shackleton, C. H. L., Pahwa, S. G., White, P. C., & Speiser, P. (1998) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(98)00052-5 · Cited by 59 · see citing works

CYP7B expression and activity in fibroblast‐like synoviocytes from patients with rheumatoid arthritis: Regulation by proinflammatory cytokines

Dulos, J., van der Vleuten, M. A. J., Kavelaars, A., Heijnen, C. J., & Boots, A. M. H. (2005) · Arthritis & Rheumatism · doi:10.1002/art.20950 · Cited by 58 · see citing works

The native anti-glucocorticoid paradigm

Muller, C., Hennebert, O., & Morfin, R. F. (2006) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2006.03.001 · Cited by 53 · see citing works

The 7α-hydroxysteroids produced in human tonsils enhance the immune response to tetanus toxoid and Bordetella pertussis antigens

Lafaye, P. J., Chmielewski, V., Nato, F., Mazié, J. C., & Morfin, R. F. (1999) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(99)00124-5 · Cited by 51 · see citing works

Metabolism of dehydroepiandrosterone by cultured human adipose stromal cells: Identification of 7α-hydroxydehydroepiandrosterone as a major metabolite using high performance liquid chromatography and mass spectrometry

Khalil, M. W., Strutt, B. J., Vachon, D., & KILLINGER, D. W. (1993) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(93)90186-z · Cited by 49 · see citing works

Circulating cortisone levels are associated with biochemical markers of bone formation and lumbar spine BMD: the Hertfordshire Cohort Study

Cooper, M. S., Syddall, H. E., Fall, C. H. D., Wood, P. J., Stewart, P. M., Cooper, C., & Dennison, E. M. (2005) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2005.02281.x · Cited by 48 · see citing works

Immunoassay of 7-hydroxysteroids: 2. Radioimmunoassay of 7α-hydroxy-dehydroepiandrosterone

Lapčı́k, O., Hampl, R., Hill, M., & Stárka, L. (1999) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(99)00145-4 · Cited by 46 · see citing works

The human cytochrome P4507B1: catalytic activity studies

Kim, S.-B., Chalbot, S., Pompon, D., Jo, D.-H., & Morfin, R. F. (2004) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2004.09.005 · Cited by 41 · see citing works

HUMAN LIVER S9 FRACTIONS: METABOLISM OF DEHYDROEPIANDROSTERONE, EPIANDROSTERONE, AND RELATED 7-HYDROXYLATED DERIVATIVES

Chalbot, S., & Morfin, R. F. (2005) · Drug Metabolism and Disposition · doi:10.1124/dmd.104.003004 · Cited by 40 · see citing works

Immunoassay of 7-hydroxysteroids: 1. Radioimmunoassay of 7β-hydroxy dehydroepiandrosterone

Lapčı́k, O., Hampl, R., Hill, M., Bičı́ková, M., & Stárka, L. (1998) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(98)00136-8 · Cited by 40 · see citing works

The Role of 11 β-Hydroxysteroid Dehydrogenase in Central Obesity and Osteoporosis

Tomlinson, J., Bujalska, I. J., Stewart, P., & Cooper, M. S. (2000) · Endocrine Research · doi:10.3109/07435800009048591 · Cited by 37 · see citing works

Enzymology of the hair follicle.

Hoffmann, R. (2001) · PubMed · Cited by 30 · see citing works

Dehydroepiandrosterone and its 7-hydroxylated metabolites do not interfere with the transactivation and cellular trafficking of the glucocorticoid receptor

Muller, C., Cluzeaud, F., Pinon, G. M., Rafestin-Oblin, M. E., & Morfin, R. F. (2004) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2004.10.014 · Cited by 30 · see citing works

Immunohistochemical detection of the human cytochrome P4507B1: production of a monoclonal antibody after cDNA immunization

Trap, C., Nato, F., Chalbot, S., Kim, S.-B., Lafaye, P. J., & Morfin, R. F. (2004) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2004.09.019 · Cited by 22 · see citing works

Use of bioconversion for the preparation of [4-14C]-labeled 7α- and 7β-hydroxylated derivatives of dehydroepiandrosterone and epiandrosterone

Chalbot, S., Trap, C., Monin, J.-P., & Morfin, R. F. (2002) · Steroids · doi:10.1016/s0039-128x(02)00072-7 · Cited by 19 · see citing works

Effects of transdermal application of 7-oxo-dhea on the levels of steroid hormones, gonadotropins and lipids in healthy men

Šulcová, J., Hill, M., Mašek, Z., Češka, R., Nováček, A., Hampl, R., & Stárka, L. (2001) · Physiological Research · doi:10.33549/physiolres.930039 · Cited by 18 · see citing works

Dünnschichtchromatographische Methode zur quantitativen Bestimmung von Cortisol, Cortison, Cortexolon, Cortexon und Corticosteron

Hartmann, F., & Illner, W. R. (1973) · Research in Experimental Medicine · doi:10.1007/bf01855109 · Cited by 9 · see citing works

11β-hydroxysteroid dehydrogenases: Intracellular gate-keepers of tissue glucocorticoid action

Chapman, K., Holmes, M., & Seckl, J. (2013) · Physiological Reviews · doi:10.1152/physrev.00020.2012 · Cited by 887 · see citing works

Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS)

Maninger, N., Wolkowitz, O. M., Reus, V. I., Epel, E. S., & Mellon, S. H. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2008.11.002 · Cited by 769 · see citing works

Sex, attachment, and the development of reproductive strategies

Giudice, M. D. (2009) · Behavioral and Brain Sciences · doi:10.1017/s0140525x09000016 · Cited by 602 · see citing works

Steroidogenesis in the skin: Implications for local immune functions

Slominski, A., Zbytek, B., Nikolakis, G., Manna, P. R., Skobowiat, C., Zmijewski, M., Li, W., Janjetovic, Z., Postlethwaite, A., Zouboulis, C. C., et al. (2013) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2013.02.006 · Cited by 369 · see citing works

Hyperandrogenemia and insulin resistance: The chief culprit of polycystic ovary syndrome

Wang, J., Wu, D., Guo, H., & Li, M. (2019) · Life Sciences · doi:10.1016/j.lfs.2019.116940 · Cited by 322 · see citing works

Intracrine androgen biosynthesis, metabolism and action revisited

Schiffer, L., Arlt, W., & Storbeck, K.-H. (2018) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.08.016 · Cited by 217 · see citing works

Dehydroepiandrosterone as a regulator of immune cell function

Hazeldine, J., Arlt, W., & Lord, J. M. (2010) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2009.12.016 · Cited by 173 · see citing works

Dehydroepiandrosterone: A neuroactive steroid

Stárka, L., Dušková, M., & Hill, M. (2014) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2014.03.008 · Cited by 170 · see citing works

Cortisol and DHEA-S levels in pregnant women with severe anxiety

Leff, P., Flores‐Ramos, M., Carrasco, A. E. Á., Martínez, M. L., Takashima, M. F. S., Coronel, F., Farfán-Labonne, B. E., Dosal, J. A. Z., Chávez-Peón, P. B., Morales, S. G., et al. (2020) · BMC Psychiatry · doi:10.1186/s12888-020-02788-6 · Cited by 137 · see citing works

Localization, Age- and Site-Dependent Expression, and Regulation of 11β-Hydroxysteroid Dehydrogenase Type 1 in Skin

Tiganescu, A., Walker, E. A., Hardy, R. S., Mayes, A. E., & Stewart, P. M. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2010.257 · Cited by 122 · see citing works

Neurosteroid, GABAergic and hypothalamic pituitary adrenal (HPA) axis regulation: what is the current state of knowledge in humans?

Crowley, S. K., & Girdler, S. S. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3572-8 · Cited by 111 · see citing works

Neuroactive steroids in periphery and cerebrospinal fluid

Kancheva, R. L., Hill, M., Novák, Z., Chrastina, J., Kancheva, L., & Stárka, L. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.05.054 · Cited by 82 · see citing works

Skin steroidogenesis in health and disease

Nikolakis, G., Stratakis, C. A., Kanaki, T., Slominski, A., & Zouboulis, C. C. (2016) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-016-9390-z · Cited by 76 · see citing works

11β-Hydroxysteroid Dehydrogenase-1 Is a Novel Regulator of Skin Homeostasis and a Candidate Target for Promoting Tissue Repair

Terao, M., Murota, H., Kimura, A., Kato, A., Ishikawa, A., Igawa, K., Miyoshi, E., & Katayama, I. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025039 · Cited by 77 · see citing works

Hair Measurements of Cortisol, DHEA, and DHEA to Cortisol Ratio as Biomarkers of Chronic Stress among People Living with HIV in China: Known-Group Validation

Qiao, S., Li, X., Zilioli, S., Chen, Z., Deng, H., Pan, J., & Guo, W. (2017) · PLoS ONE · doi:10.1371/journal.pone.0169827 · Cited by 66 · see citing works

Simultaneous determination of hair cortisol, cortisone and DHEAS with liquid chromatography–electrospray ionization-tandem mass spectrometry in negative mode

Chen, Z., Li, J., Zhang, J., Xing, X., Gao, W., Lu, Z., & Deng, H. (2013) · Journal of Chromatography B · doi:10.1016/j.jchromb.2013.04.026 · Cited by 64 · see citing works

Evaluation of hair cortisol and cortisone change during pregnancy and the association with self-reported depression, somatization, and stress symptoms

Scharlau, F., Pietzner, D., Vogel, M., Gaudl, A., Ceglarek, U., Thiery, J., Kratzsch, J., Hiemisch, A., & Kieß, W. (2017) · Stress · doi:10.1080/10253890.2017.1392507 · Cited by 62 · see citing works

Peripheral neuroactive steroids may be as good as the steroids in the cerebrospinal fluid for the diagnostics of CNS disturbances

Kancheva, R. L., Hill, M., Novák, Z., Chrastina, J., Velíková, M., Kancheva, L., Říha, I., & Stárka, L. (2009) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2009.12.006 · Cited by 61 · see citing works

Growth hormone, dehydroepiandrosterone and adiponectin levels in non‐alcoholic steatohepatitis: an endocrine signature for advanced fibrosis in obese patients

Koehler, E. M., Swain, J. M., Sanderson, S. O., Krishnan, A., Watt, K. D. S., & Charlton, M. (2011) · Liver International · doi:10.1111/j.1478-3231.2011.02637.x · Cited by 60 · see citing works

Oxidative metabolism of dehydroepiandrosterone (DHEA) and biologically active oxygenated metabolites of DHEA and epiandrosterone (EpiA) – Recent reports

Kihel, L. E. (2011) · Steroids · doi:10.1016/j.steroids.2011.09.008 · Cited by 54 · see citing works

Anti-inflammatory effects and changes in prostaglandin patterns induced by 7β-hydroxy-epiandrosterone in rats with colitis

Hennebert, O., Pélissier, M. A., Mée, S. L., Wülfert, E., & Morfin, R. F. (2008) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2007.12.014 · Cited by 43 · see citing works

Hair glucocorticoids as a biomarker for endogenous Cushing's syndrome: validation in two independent cohorts

Savas, M., Wester, V. L., de Rijke, Y. B., Rubinstein, G., Zopp, S., Dorst, K., van den Berg, S. A. A., Beuschlein, F., Feelders, R. A., Reincke, M., et al. (2019) · Neuroendocrinology · doi:10.1159/000498886 · Cited by 41 · see citing works

Human microsomal carbonyl reducing enzymes in the metabolism of xenobiotics: well-known and promising members of the SDR superfamily

Zemanová, L., & Wsól, V. (2011) · Drug Metabolism Reviews · doi:10.3109/03602532.2011.638304 · Cited by 39 · see citing works

Characterisation of the cancer-associated glucocorticoid system: key role of 11β-hydroxysteroid dehydrogenase type 2

Cirillo, N., Morgan, D. J., Pedicillo, M. C., Celentano, A., Muzio, L. L., McCullough, M. J., & Prime, S. S. (2017) · British Journal of Cancer · doi:10.1038/bjc.2017.243 · Cited by 40 · see citing works

Biotransformation of steroids by entomopathogenic strains of Isaria farinosa

Kozłowska, E., Hoc, N., Sycz, J., Urbaniak, M., Dymarska, M., Grzeszczuk, J., Kostrzewa-Susłow, E., Stępień, Ł., Pląskowska, E., & Janeczko, T. (2018) · Microbial Cell Factories · doi:10.1186/s12934-018-0920-0 · Cited by 39 · see citing works

Local blockade of glucocorticoid activation reverses stress‐ and glucocorticoid‐induced delays in cutaneous wound healing

Youm, J., Park, K., Uchida, Y., Chan, A., Mauro, T. M., Holleran, W. M., & Elias, P. M. (2013) · Wound Repair and Regeneration · doi:10.1111/wrr.12083 · Cited by 33 · see citing works

Central intracrine DHEA synthesis in ageing-related neuroinflammation and neurodegeneration: therapeutic potential?

Powrie, Y. S. L., & Smith, C. (2018) · Journal of Neuroinflammation · doi:10.1186/s12974-018-1324-0 · Cited by 35 · see citing works

11β-Hydroxysteroid dehydrogenase 1 contributes to the pro-inflammatory response of keratinocytes

Itoi, S., Terao, M., Murota, H., & Katayama, I. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.09.065 · Cited by 34 · see citing works

7β-Hydroxy-epiandrosterone-mediated regulation of the prostaglandin synthesis pathway in human peripheral blood monocytes

Mée, S. L., Hennebert, O., Ferrec, C., Wülfert, E., & Morfin, R. F. (2008) · Steroids · doi:10.1016/j.steroids.2008.05.001 · Cited by 33 · see citing works

Microarray Analysis of Differentially-Expressed Genes Encoding CYP450 and Phase II Drug Metabolizing Enzymes in Psoriasis and Melanoma

Sumantran, V. N., Mishra, P., Bera, R., & Natarajan, S. (2016) · Pharmaceutics · doi:10.3390/pharmaceutics8010004 · Cited by 31 · see citing works

Expression profiles of cortisol‐inactivating enzyme, 11β‐hydroxysteroid dehydrogenase‐2, in human epidermal tumors and its role in keratinocyte proliferation

Terao, M., Itoi, S., Murota, H., & Katayama, I. (2012) · Experimental Dermatology · doi:10.1111/exd.12075 · Cited by 29 · see citing works

Epimerase activity of the human 11β-hydroxysteroid dehydrogenase type 1 on 7-hydroxylated C19-steroids

Hennebert, O., Montes, M., Favre-Reguillon, A., Chermette, H., Ferroud, C., & Morfin, R. (2009) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2008.12.015 · Cited by 27 · see citing works

7α-Hydroxytestosterone Affects 11β-Hydroxysteroid Dehydrogenase 1 Direction in Rat Leydig Cells

Hu, G., Lian, Q., Chen, B., Prasad, P. V., Kumar, N., Zheng, Z., & Ge, R. (2009) · Endocrinology · doi:10.1210/en.2009-0917 · Cited by 25 · see citing works

Preliminary evidence of altered steroidogenesis in women with Alzheimer’s disease: Have the patients “OLDER” adrenal zona reticularis?

Vaňková, M., Hill, M., Velíková, M., Včelák, J., Vacínová, G., Dvořáková, K., Lukášová, P., Vejražková, D., Rusina, R., Holmerová, I., et al. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2015.12.011 · Cited by 21 · see citing works

Dietary licorice enhances in vivo cadmium detoxification and modulates gut microbial metabolism in mice

Zheng, X. S., Wang, L., You, L., Liu, Y., Cohen, M., Tian, S., Li, W., & Li, X. (2022) · iMeta · doi:10.1002/imt2.7 · Cited by 20 · see citing works

The 7-hydroxylation of dehydroepiandrosterone in rat brain

Li, A., & Bigelow, J. C. (2010) · Steroids · doi:10.1016/j.steroids.2010.02.003 · Cited by 19 · see citing works

Hair cortisol and dehydroepiandrosterone concentrations: Associations with executive function in early childhood

Hennessey, E. P., Kepinska, O., Haft, S. L., Chan, M., Sunshine, I., Jones, C. L., Hancock, R., & Hoeft, F. (2020) · Biological Psychology · doi:10.1016/j.biopsycho.2020.107946 · Cited by 17 · see citing works

Sex steroids and glucocorticoid ratios in Iberian lynx hair

Azevedo, A., Wauters, J., Kirschbaum, C., Serra, R., Rivas, A., & Jewgenow, K. (2020) · Conservation Physiology · doi:10.1093/conphys/coaa075 · Cited by 17 · see citing works

Evolution of neuroendocrine mechanisms linking attachment and life history: The social neuroendocrinology of middle childhood

Flinn, M. V., Muehlenbein, M. P., & Ponzi, D. (2009) · Behavioral and Brain Sciences · doi:10.1017/s0140525x09000089 · Cited by 15 · see citing works

Dehydroepiandrosterone and 7-oxo-dehydroepiandrosterone in male reproductive health: Implications of differential regulation of human Sertoli cells metabolic profile

Dias, T. R., Alves, M. G., Almeida, S., Silva, J., Barros, A., Sousa, M., Silva, B. M., Silvestre, S., & Oliveira, P. F. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2015.06.004 · Cited by 14 · see citing works

5α-Androstane-3β,7α,17β-triol and 5α-androstane-3β,7β,17β-triol as substrates for the human 11β-hydroxysteroid dehydrogenase type 1

Hennebert, O., LEMEE, S., Pernelle, C., & Morfin, R. F. (2007) · Steroids · doi:10.1016/j.steroids.2007.07.011 · Cited by 14 · see citing works

Therapeutic effect of Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. leaves on ischemic stroke via the microbiota–gut–brain axis

Wang, R., Sun, Y., Wang, M., Li, H., Liu, S., & Liu, Z. (2023) · Phytotherapy Research · doi:10.1002/ptr.7947 · Cited by 14 · see citing works

Pharmacological Bases of Coffee Nutrients for Diabetes Prevention

Oka, K. (2007) · YAKUGAKU ZASSHI · doi:10.1248/yakushi.127.1825 · Cited by 12 · see citing works

Modulation of 11β-hydroxysteroid dehydrogenase functions by the cloud of endogenous metabolites in a local microenvironment: The glycyrrhetinic acid-like factor (GALF) hypothesis

Morris, D. J., Brem, A. S., & Odermatt, A. (2021) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2021.105988 · Cited by 13 · see citing works

Stress biomarkers in the tear film

Banbury, L. K. (2009) · Cross Connect (Southern Cross University) · Cited by 11 · see citing works

New insights into the protective effects of DHEA 1)

Niro, S., Hennebert, O., & Morfin, R. F. (2010) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci.2010.050 · Cited by 11 · see citing works

Metabolomic profiling of intrauterine growth-restricted preterm infants: a matched case–control study

Priante, E., Verlato, G., Stocchero, M., Giordano, G., Pirillo, P., Bonadies, L., Visentin, S., Moschino, L., & Baraldi, E. (2022) · Pediatric Research · doi:10.1038/s41390-022-02292-5 · Cited by 11 · see citing works

Increased Serum Levels of C21 Steroids in Female Patients With Multiple Sclerosis

Kančeva, R., Stárka, L., Kancheva, L., Hill, M., Velíková, M., & Havrdová, E. (2015) · Physiological Research · doi:10.33549/physiolres.933145 · Cited by 11 · see citing works

The moderating effect of cortisol and dehydroepiandrosterone on the relation between sleep and depression or burnout

Rothe, N., Vogel, S., Schmelzer, K., Kirschbaum, C., Penz, M. S., Wekenborg, M., Gao, W., & Walther, A. (2021) · Comprehensive Psychoneuroendocrinology · doi:10.1016/j.cpnec.2021.100051 · Cited by 11 · see citing works

Local corticosterone activation by 11β-hydroxysteroid dehydrogenase 1 in keratinocytes: the role in narrow-band UVB-induced dermatitis

Itoi‐Ochi, S., Terao, M., Murota, H., & Katayama, I. (2016) · Dermato-Endocrinology · doi:10.1080/19381980.2015.1119958 · Cited by 10 · see citing works

Circulating steroids negatively correlate with tinnitus

Chrbolka, P., Palúch, Z., Hill, M., & Alusik, S. (2017) · Steroids · doi:10.1016/j.steroids.2017.04.004 · Cited by 10 · see citing works

Patients With IgA Nephropathy Have Altered Levels of Immunomodulatory C19 Steroids. Glucocorticoid Therapy With Addition of Adrenal Androgens May Be the Choice

Sterzl, I., Hill, M., Stárka, L., Velíková, M., Kančeva, R., Jemelková, J., Czerneková, L., Kosztyu, P., Zadražil, J., Matoušovic, K., et al. (2017) · Physiological Research · doi:10.33549/physiolres.933732 · Cited by 10 · see citing works

Altered Steroidome in Women with Gestational Diabetes Mellitus: Focus on Neuroactive and Immunomodulatory Steroids from the 24th Week of Pregnancy to Labor

Ondřejíková, L., Pařı́zek, A., Šimják, P., Vejražková, D., Velíková, M., Anderlová, K., Vosátková, M., Krejčí, H., Koucký, M., Kancheva, R. L., et al. (2021) · Biomolecules · doi:10.3390/biom11121746 · Cited by 10 · see citing works

Changes of BMI, steroid metabolome and psychopathology in patients with anorexia nervosa during hospitalization

Bulant, J., Hill, M., Velíková, M., Yamamotová, A., Pavel Martasek, E., & Papežová, H. (2019) · Steroids · doi:10.1016/j.steroids.2019.108523 · Cited by 9 · see citing works

The origin of 7α-hydroxy-dehydroepiandrosterone and its physiological role: a history of discoveries

STÁRKA, L. (2017) · Physiological Research · doi:10.33549/physiolres.933717 · Cited by 8 · see citing works

Daily Profiles of Dehydroepiandrosterone and Its Hydroxylated Metabolites with Respect to Food Intake

Stárka, L., Rácz, B., Šrámková, M., Hill, M., & Dušková, M. (2015) · Prague Medical Report · doi:10.14712/23362936.2015.44 · Cited by 8 · see citing works

Altered Steroidome in Women with Multiple Sclerosis

Kancheva, R. L., Hill, M., Velíková, M., Kancheva, L. S., Včelák, J., Ampapa, R., Židó, M., Štětkářová, I., Libertínová, J., Vosátková, M., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252212033 · Cited by 8 · see citing works

7α-Hydroxylation of dehydroepiandrosterone does not interfere with the activation of glucocorticoids by 11β-hydroxysteroid dehydrogenase in EtC cerebellar neurons

Gottfried‐Blackmore, A., Jellinck, P. H., Vecchiarelli, H. A., Masheeb, Z., Kaufmann, M., McEwen, B. S., & Bulloch, K. (2013) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2013.07.001 · Cited by 9 · see citing works

7-oxygenated Derivatives of Dehydroepiandrosterone and Obesity

Sedláčková, B., Dušátková, L., Zamrazilová, H., Matucha, P., Bičı́ková, M., & Stárka, L. (2012) · Prague Medical Report · doi:10.14712/23362936.2015.29 · Cited by 8 · see citing works

Dehydroepiandrosterone and Dehydroepiandrosterone-Sulfate and Emotional Processing

do Vale, S., & Escera, C. (2018) · Vitamins and hormones · doi:10.1016/bs.vh.2018.01.022 · Cited by 7 · see citing works

Investigating the effects of childhood maltreatment on pro-inflammatory signaling: The influence of cortisol and DHEA on cytokine secretion ex vivo

Geiger, M. L., Boeck, C., Koenig, A. M., Schury, K., Waller, C., Kolassa, S., Karabatsiakis, A., & Kolassa, I. (2018) · Mental Health & Prevention · doi:10.1016/j.mhp.2018.04.002 · Cited by 7 · see citing works

A native steroid hormone derivative triggers the resolution of inflammation

Niro, S., Hennebert, O., & Morfin, R. F. (2009) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci.2010.001 · Cited by 6 · see citing works

A systematic review of the impact of 7-keto-DHEA on body weight

Jeyaprakash, N., Maeder, S., Janka, H., & Stute, P. (2022) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-022-06884-8 · Cited by 6 · see citing works

Association between hair cortisol concentration and behavioral difficulties in children and adolescents

Jahns, C. C., Poulain, T., Vogel, M., & Kieß, W. (2022) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2022.105795 · Cited by 5 · see citing works

Glucocorticoids and mineralocorticoids in hair: facilitating accurate diagnosis of adrenal-related endocrine disorders

Heyns, B., Pieters, R., Stander, M. A., Atkin, S. L., & Swart, A. C. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1448013 · Cited by 4 · see citing works

Disorganized attachment and reproductive strategies

Lewis, A. J., & Tooley, G. A. (2009) · Behavioral and Brain Sciences · doi:10.1017/s0140525x0900017x · Cited by 4 · see citing works

Steroid Hormones Related to 11β-hydroxysteroid Dehydrogenase Type 1 in Treated Obesity

Máčová, L., SOSVOROVÁ, L., Vítků, J., Bičı́ková, M., Hill, M., Zamrazilová, H., Sedláčková, B., & Stárka, L. (2015) · Physiological Research · doi:10.33549/physiolres.933073 · Cited by 4 · see citing works

Glucocorticoid Metabolism and Activation

Othonos, N., & Tomlinson, J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.64302-7 · Cited by 3 · see citing works

Steroidomics in Men with Schizophrenia

Hill, M., Velíková, M., Hovorková, T., Bulant, J., Janšáková, K., & Valeš, K. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25168729 · Cited by 3 · see citing works

Fecal Microbiota and Hair Glucocorticoid Concentration Show Associations with Growth during Early Life in a Pig Model

González-Solé, F., Solà‐Oriol, D., Villagómez‐Estrada, S., Melo‐Durán, D., López, L. V., Román, N. V., López-Arjona, M., & Pérez, J. F. (2022) · Nutrients · doi:10.3390/nu14214639 · Cited by 4 · see citing works

Effects of menopause on hepatic 11β-hydroxysteroid dehydrogenase type 1 activity and adrenal sensitivity to adrenocorticotropin in healthy non-obese women

Li, S., Liu, W., Wang, L., Huang, R., Chen, Q., Wu, Y., & Cai, Y. (2011) · Gynecological Endocrinology · doi:10.3109/09513590.2010.507288 · Cited by 2 · see citing works

The Response of C19 Δ5-steroids to ACTH Stimulation and Hypoglycemia in Insulin Tolerance Test for Adrenal Insufficiency

Dušková, M., Kolátorová, L., Hill, M., Šimůnková, K., Jandíková, H., Pospíšilová, H., Šrámková, M., Kosák, M., Kršek, M., Hána, V., et al. (2016) · Prague Medical Report · doi:10.14712/23362936.2016.10 · Cited by 2 · see citing works

Effect of Treatment on Steroidome in Women with Multiple Sclerosis

Hill, M., Kancheva, R. L., Velíková, M., Kancheva, L., Včelák, J., Ampapa, R., Židó, M., Štětkářová, I., Libertínová, J., Vosátková, M., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26051835 · Cited by 1 · see citing works

PPROMEDIA – Database of Chemical Substances the Potential Biomarkers of Diseases with the Meaning in Noninvasive Diagnostics

Saik, O. V. (2011) · Mathematical Biology and Bioinformatics · doi:10.17537/2011.6.250 · Cited by 1 · see citing works

Dopamine Gene Polymorphism, Biochemical and Oxidative Stress Parameters in Geriatric Population with and Without Depression: A Pilot Study

Mahdi, R. A., Ahmad, I., Jilani, T., Ansari, J. A., Mahdi, F., Mahdi, A. A., & Jafar, T. (2021) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-020-00928-z · Cited by 1 · see citing works

Resolution of Colitis-Associated Inflammation

Hennebert, O., Pélissier, M. A., & Morfin, R. F. (2012) · InTech eBooks · doi:10.5772/26779

The role of DHEA in the aetiology of modern chronic disease

Powrie, Y. S. L. (2020) · SUNScholar (Stellenbosch University)

Screening Dietary Herbs for Health Intervention on Mass Cadmium PoisoningPreprint

Zheng, X., Wang, L., You, L., Liu, Y., Cohen, M., Tian, S., Li, W., & Li, X. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3940277

Glucocorticoid metabolism and activation

Othonos, N., & Tomlinson, J. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-13825-6.00210-7

Inter-conversion of 7α- and 7β-hydroxy-dehydroepiandrosterone by the human 11β-hydroxysteroid dehydrogenase type 1

Muller, C., Pompon, D., Urban, P., & Morfin, R. (2006) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2005.12.001 · Cited by 77 · see citing works

Dehydroepiandrosterone Metabolites and their Interactions in Humans

Chalbot, S., & Morfin, R. F. (2006) · Drug metabolism and drug interactions · doi:10.1515/dmdi.2006.22.1.1 · Cited by 33 · see citing works

The native anti-glucocorticoid paradigm

Muller, C., Hennebert, O., & Morfin, R. F. (2006) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2006.03.001 · Cited by 53 · see citing works

Dehydroepiandrosterone and Its CYP7B1 Metabolite 7α-Hydroxydehydroepiandrosterone Regulates 11β-Hydroxysteroid Dehydrogenase 1 Directions in Rat Leydig Cells

Zhu, Q., Dong, Y., Li, X., Ni, C., Huang, T., Sun, J., & Ge, R. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00886 · Cited by 7 · see citing works

Glucocorticoids inhibit interconversion of 7-hydroxy and 7-oxo metabolites of dehydroepiandrosterone: a role for 11β-hydroxysteroid dehydrogenases?

Robinzon, B., Michael, K. K., Ripp, S. L., Winters, S. J., & Prough, R. A. (2003) · Archives of Biochemistry and Biophysics · doi:10.1016/s0003-9861(03)00056-0 · Cited by 70 · see citing works