Roles of PLODs in Collagen Synthesis and Cancer Progression

Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin

Aziz, J., Shezali, H., Radzi, Z., Yahya, N. A., Abu Kassim, N. H., Czernuszka, J., & Rahman, M. T. (2016) · Skin Pharmacology and Physiology · doi:10.1159/000447017 · Cited by 7,323 · see citing works

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

Levental, K. R., Yu, H., Kass, L., Lakins, J. N., Egeblad, M., Erler, J. T., Fong, S. F. T., Csiszar, K., Giaccia, A., Weninger, W., et al. (2009) · Cell · doi:10.1016/j.cell.2009.10.027 · Cited by 4,101 · see citing works

Tumour-educated macrophages promote tumour progression and metastasis

Pollard, J. W. (2004) · Nature reviews. Cancer · doi:10.1038/nrc1256 · Cited by 3,365 · see citing works

Collagen reorganization at the tumor-stromal interface facilitates local invasion

Provenzano, P. P., Eliceiri, K. W., Campbell, J. M., Inman, D. R., White, J. G., & Keely, P. J. (2006) · BMC Medicine · doi:10.1186/1741-7015-4-38 · Cited by 1,804 · see citing works

Collagen density promotes mammary tumor initiation and progression

Provenzano, P. P., Inman, D. R., Eliceiri, K. W., Knittel, J. G., Yan, L., Rueden, C., White, J. G., & Keely, P. J. (2008) · BMC Medicine · doi:10.1186/1741-7015-6-11 · Cited by 1,364 · see citing works

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

Conklin, M. W., Eickhoff, J. C., Riching, K. M., Pehlke, C. A., Eliceiri, K. W., Provenzano, P. P., Friedl, A., & Keely, P. J. (2011) · American Journal Of Pathology · doi:10.1016/j.ajpath.2010.11.076 · Cited by 1,293 · see citing works

Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus

Saito, M., & Marumo, K. (2009) · Osteoporosis International · doi:10.1007/s00198-009-1066-z · Cited by 914 · see citing works

Dynamic interplay between the collagen scaffold and tumor evolution

Egeblad, M., Rasch, M. G., & Weaver, V. M. (2010) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2010.08.015 · Cited by 898 · see citing works

Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition

Xiong, G., Deng, L., Zhu, J., Rychahou, P. G., & Xu, R. (2014) · BMC Cancer · doi:10.1186/1471-2407-14-1 · Cited by 756 · see citing works

Basement Membrane Proteins: Structure, Assembly, and Cellular Interactions

Mats Paulsson, M. (1992) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409239209082560 · Cited by 603 · see citing works

Lysine post-translational modifications of collagen

Yamauchi, M., & Sricholpech, M. (2012) · Essays in Biochemistry · doi:10.1042/bse0520113 · Cited by 566 · see citing works

The collagen family members as cell adhesion proteins

Heino, J. (2007) · BioEssays · doi:10.1002/bies.20636 · Cited by 439 · see citing works

A Collagen-Remodeling Gene Signature Regulated by TGF-β Signaling Is Associated with Metastasis and Poor Survival in Serous Ovarian Cancer

Cheon, D., Tong, Y., Sim, M., Dering, J., Berel, D., Cui, X., Lester, J., Beach, J. A., Tighiouart, M., Walts, A. E., et al. (2013) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-13-1256 · Cited by 374 · see citing works

Transmembrane collagen receptors

Leitinger, B. (2011) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-092910-154013 · Cited by 354 · see citing works

Collagen Hydroxylases and the Protein Disulfide Isomerase Subunit of Prolyl 4‐Hydroxylases

Kivirikko, K. I., & Pihlajaniemi, T. A. (1998) · Advances in enzymology and related areas of molecular biology/Advances in enzymology and related subjects · doi:10.1002/9780470123188.ch9 · Cited by 313 · see citing works

Hypoxia-Dependent Modification of Collagen Networks Promotes Sarcoma Metastasis

Eisinger‐Mathason, T. S. K., Zhang, M., Qiu, Q., Skuli, N., Nakazawa, M. S., Karakasheva, T. A., Mucaj, V., Shay, J. E. S., Stangenberg, L., Sadri, N., et al. (2013) · Cancer Discovery · doi:10.1158/2159-8290.cd-13-0118 · Cited by 280 · see citing works

Proline Precursors and Collagen Synthesis: Biochemical Challenges of Nutrient Supplementation and Wound Healing

Albaugh, V. L., Mukherjee, K., & Barbul, A. (2017) · Journal of Nutrition · doi:10.3945/jn.117.256404 · Cited by 269 · see citing works

Collagen: Structure, function, and metabolism in normal and fibrotic tissues

Nimni, M. E. (1983) · Seminars in Arthritis and Rheumatism · doi:10.1016/0049-0172(83)90024-0 · Cited by 266 · see citing works

Selective Binding of Collagen Subtypes by Integrin α1I, α2I, and α10I Domains

Tulla, M., Pentikäinen, O. T., Viitasalo, T., Käpylä, J., Impola, U., Nykvist, P., Nissinen, L. M., Johnson, M. S., & Heino, J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m104058200 · Cited by 257 · see citing works

α11β1 Integrin Is a Receptor for Interstitial Collagens Involved in Cell Migration and Collagen Reorganization on Mesenchymal Nonmuscle Cells

Tiger, C., Fougerousse, F., Grundström, G., Velling, T., & Gullberg, D. (2001) · Developmental Biology · doi:10.1006/dbio.2001.0363 · Cited by 235 · see citing works

Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma

Paňková, D., Chen, Y., Terajima, M., Schliekelman, M. J., Baird, B. N., Fahrenholtz, M. M., Sun, L., Gill, B. J., Vadakkan, T. J., Kim, M. P., et al. (2015) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-15-0307 · Cited by 233 · see citing works

Isolation, Cloning, and Sequence Analysis of the Integrin Subunit α10, a β1-associated Collagen Binding Integrin Expressed on Chondrocytes

Camper, L., Hellman, U., & Lundgren-Åkerlund, E. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.32.20383 · Cited by 228 · see citing works

Molecular Analysis of Collagen Binding by the Human Discoidin Domain Receptors, DDR1 and DDR2

Leitinger, B. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m301370200 · Cited by 219 · see citing works

Tumor Cell–Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression

Oudin, M. J., Jonas, O. H., Kosciuk, T., Broye, L. C., Guido, B. C., Wyckoff, J., Riquelme, D. N., Lamar, J. M., Asokan, S. B., Whittaker, C. A., et al. (2016) · Cancer Discovery · doi:10.1158/2159-8290.cd-15-1183 · Cited by 206 · see citing works

Identification and validation of genes involved in cervical tumourigenesis

Rajkumar, T., Sabitha, K., Vijayalakshmi, N., Shirley, S., Bose, M. V., Gopisetty, G., & Selvaluxmy, G. (2011) · BMC Cancer · doi:10.1186/1471-2407-11-80 · Cited by 183 · see citing works

Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma

Chen, Y., Terajima, M., Yang, Y., Sun, L., Ahn, Y., Paňková, D., Puperi, D. S., Watanabe, T., Kim, M. P., Blackmon, S. H., et al. (2015) · Journal of Clinical Investigation · doi:10.1172/jci74725 · Cited by 181 · see citing works

Tumour-suppressive miRNA-26a-5p and miR-26b-5p inhibit cell aggressiveness by regulating PLOD2 in bladder cancer

Miyamoto, K., Seki, N., Matsushita, R., Yonemori, M., Yoshino, H., Nakagawa, M., & Enokida, H. (2016) · British Journal of Cancer · doi:10.1038/bjc.2016.179 · Cited by 167 · see citing works

Chaperone Hsp47 Drives Malignant Growth and Invasion by Modulating an ECM Gene Network

Zhu, J., Xiong, G., Fu, H., Evers, B. M., Zhou, B. P., & Xu, R. (2015) · Cancer Research · doi:10.1158/0008-5472.can-14-1027 · Cited by 140 · see citing works

Cloning of human lysyl hydroxylase: Complete cDNA-derived amino acid sequence and assignment of the gene (PLOD) to chromosome 1p36.3→p36.2

Hautala, T., Byers, M. G., Eddy, R. L., Shows, T. B., Kivirikko, K. I., & Myllylä, R. (1992) · Genomics · doi:10.1016/0888-7543(92)90202-4 · Cited by 139 · see citing works

Lysyl Hydroxylase 3 Is a Multifunctional Protein Possessing Collagen Glucosyltransferase Activity

Heikkinen, J., Risteli, M., Wang, C., Latvala, J., Rossi, M., Valtavaara, M., & Myllylä, R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m006203200 · Cited by 139 · see citing works

A Connective Tissue Disorder Caused by Mutations of the Lysyl Hydroxylase 3 Gene

Salo, A. M., Cox, H., Farndon, P. A., Moss, C., Grindulis, H., Risteli, M., Robins, S. P., & Myllylä, R. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2008.09.004 · Cited by 135 · see citing works

Decarboxylation of alpha-ketoglutarate coupled to collagen proline hydroxylase.

Rhoads, R. E., & Udenfriend, S. (1968) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.60.4.1473 · Cited by 128 · see citing works

Primary Structure, Tissue Distribution, and Chromosomal Localization of a Novel Isoform of Lysyl Hydroxylase (Lysyl Hydroxylase 3)

Valtavaara, M., Szpirer, C., Szpirer, J., & Myllylä, R. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.21.12881 · Cited by 128 · see citing works

Function of cancer cell-derived extracellular matrix in tumor progression

Xiong, G., & Xu, R. (2016) · Journal of Cancer Metastasis and Treatment · doi:10.20517/2394-4722.2016.08 · Cited by 128 · see citing works

The E2F Transcription Factors Regulate Tumor Development and Metastasis in a Mouse Model of Metastatic Breast Cancer

Hollern, D. P., Honeysett, J., Cardiff, R. D., & Andrechek, E. R. (2014) · Molecular and Cellular Biology · doi:10.1128/mcb.00737-14 · Cited by 123 · see citing works

Collagen: An Overview

Patino, M. G., Neiders, M. E., Andreana, S., Noble, B. K., & Cohen, R. E. (2002) · Implant Dentistry · doi:10.1097/00008505-200207000-00014 · Cited by 123 · see citing works

Barrier to autointegration factor 1, procollagen‐lysine, 2‐oxoglutarate 5‐dioxygenase 3, and splicing factor 3b subunit 4 as early‐stage cancer decision markers and drivers of hepatocellular carcinoma

Shen, Q., Eun, J. W., Lee, K., Kim, H. S., Yang, H. D., Kim, S. Y., Lee, E. K., Kim, T., Kang, K., Kim, S., et al. (2017) · Hepatology · doi:10.1002/hep.29606 · Cited by 120 · see citing works

Premature aggregation of type IV collagen and early lethality in lysyl hydroxylase 3 null mice

Rautavuoma, K., Takaluoma, K., Sormunen, R. T., Myllyharju, J., Kivirikko, K. I., & Soininen, R. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404966101 · Cited by 113 · see citing works

Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via PI3K/Akt signaling in glioma

Song, Y., Zheng, S., Wang, J., Long, H., Fang, L., Wang, G., Li, Z., Que, T., Liu, Y., Li, Y., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.16710 · Cited by 109 · see citing works

Phenotypic variability of the kyphoscoliotic type of Ehlers-Danlos syndrome (EDS VIA): clinical, molecular and biochemical delineation

Rohrbach, M., Vandersteen, A., Yiş, U., Serdaroglu, G., Ataman, E., Chopra, M., Garcia, S., Jones, K., Kariminejad, A., Kraenzlin, M., et al. (2011) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-6-46 · Cited by 106 · see citing works

Tumor-expressed collagens can modulate immune cell function through the inhibitory collagen receptor LAIR-1

Rygiel, T. P., Stolte, E. H., Ruiter, T. E.-D., van de Weijer, M. L., & Meyaard, L. (2011) · Molecular Immunology · doi:10.1016/j.molimm.2011.09.006 · Cited by 104 · see citing works

Hypoxia and TGF-β1 induced PLOD2 expression improve the migration and invasion of cervical cancer cells by promoting epithelial-to-mesenchymal transition (EMT) and focal adhesion formation

Xu, F., Zhang, J., Hu, G., Liu, L., & Liang, W. (2017) · Cancer Cell International · doi:10.1186/s12935-017-0420-z · Cited by 104 · see citing works

Regulation of the collagen cross-linking enzymes LOXL2 and PLOD2 by tumor-suppressive microRNA-26a/b in renal cell carcinoma

Kurozumi, A., Kato, M., Goto, Y., Matsushita, R., Nishikawa, R., Okato, A., FUKUMOTO, I., Ichikawa, T., & Seki, N. (2016) · International Journal of Oncology · doi:10.3892/ijo.2016.3440 · Cited by 100 · see citing works

Age-related variations in hydroxylation of lysine and proline in collagen

Barnes, M. J., Constable, B. J., Morton, L. F., & Royce, P. M. (1974) · Biochemical Journal · doi:10.1042/bj1390461 · Cited by 97 · see citing works

PLOD2 regulated by transcription factor FOXA1 promotes metastasis in NSCLC

Du, H., Chen, Y., Hou, X., Huang, Y., Wei, X., Yu, X., Feng, S. L., Wu, Y., Zhan, M., Shi, X., et al. (2017) · Cell Death and Disease · doi:10.1038/cddis.2017.553 · Cited by 97 · see citing works

Cofactor requirements for the enzymatic hydroxylation of lysine in a polypeptide precursor of collagen

Hausmann, E. (1967) · Biochimica et Biophysica Acta (BBA) - Protein Structure · doi:10.1016/0005-2795(67)90566-1 · Cited by 95 · see citing works

Hypoxic stellate cells of pancreatic cancer stroma regulate extracellular matrix fiber organization and cancer cell motility

Sada, M., Ohuchida, K., Horioka, K., Okumura, T., Moriyama, T., Miyasaka, Y., Ohtsuka, T., Mizumoto, K., Oda, Y., & Nakamura, M. (2016) · Cancer Letters · doi:10.1016/j.canlet.2016.01.016 · Cited by 94 · see citing works

Association of candidate gene polymorphisms with bone mineral density in community-dwelling Japanese women and men

Yamada, Y., Ando, F., & Shimokata, H. (2007) · International Journal of Molecular Medicine · doi:10.3892/ijmm.19.5.791 · Cited by 89 · see citing works

PLOD 2 induced under hypoxia is a novel prognostic factor for hepatocellular carcinoma after curative resection

Noda, T., Yamamoto, H., Takemasa, I., Yamada, D., Uemura, M., Wada, H., Kobayashi, S., Marubashi, S., Eguchi, H., Tanemura, M., et al. (2011) · Liver International · doi:10.1111/j.1478-3231.2011.02619.x · Cited by 89 · see citing works

Pitx2 Regulates Procollagen Lysyl Hydroxylase (Plod) Gene Expression

Hjalt, T. Å. H., Amendt, B. A., & Murray, J. C. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.152.3.545 · Cited by 88 · see citing works

Secretion and Assembly of Type IV and VI Collagens Depend on Glycosylation of Hydroxylysines

Sipilä, L., Ruotsalainen, H. J., Sormunen, R. T., Baker, N. L., Lamandé, S. R., Vapola, M. H., Wang, C., Sado, Y., Aszódi, A., & Myllylä, R. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m704198200 · Cited by 86 · see citing works

Loss of Type I Collagen Telopeptide Lysyl Hydroxylation Causes Musculoskeletal Abnormalities in a Zebrafish Model of Bruck Syndrome

Gistelinck, C., Witten, P. E., Huysseune, A., Symoens, S., Malfait, F., Larionova, D., Simoens, P., Dierick, M., Hoorebeke, L. V., Paepe, A. D., et al. (2016) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2977 · Cited by 83 · see citing works

Lysyl Hydroxylase 2 Is Secreted by Tumor Cells and Can Modify Collagen in the Extracellular Space

Chen, Y., Guo, H., Terajima, M., Banerjee, P., Liu, X., Jiang, Y. L., Momin, A. A., Katayama, H., Hanash, S., Burns, A. R., et al. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.759803 · Cited by 79 · see citing works

Mutation analysis of the PLOD1 gene: An efficient multistep approach to the molecular diagnosis of the kyphoscoliotic type of Ehlers-Danlos syndrome (EDS VIA)

Giunta, C., Randolph, A. E., & Steinmann, B. U. (2005) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2005.04.014 · Cited by 78 · see citing works

Mapping of Potent and Specific Binding Motifs, GLOGEN and GVOGEA, for Integrin α1β1 Using Collagen Toolkits II and III

Hamaia, S. W., Pugh, N., Raynal, N., Némoz, B., Stone, R., Gullberg, D., Bihan, D. G., & Farndale, R. W. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.353144 · Cited by 74 · see citing works

Alu-Alu recombination results in a duplication of seven exons in the lysyl hydroxylase gene in a patient with the type VI variant of Ehlers-Danlos syndrome.

Pousi, B., Hautala, T., Heikkinen, J., PAJUNEN, L., Kivirikko, K. I., & Myllylä, R. (1994) · PubMed Central · Cited by 73 · see citing works

Lysyl Hydroxylase 3 Glucosylates Galactosylhydroxylysine Residues in Type I Collagen in Osteoblast Culture

Sricholpech, M., Perdivara, I., Nagaoka, H., Yokoyama, M., Tomer, K. B., & Yamauchi, M. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.178509 · Cited by 72 · see citing works

TGF-ß induces Lysyl hydroxylase 2b in human synovial osteoarthritic fibroblasts through ALK5 signaling

Remst, D. F. G., Davidson, E. N. B., Vitters, E. L., Bank, R. A., van den Berg, W. B., & van der Kraan, P. M. (2013) · Cell and Tissue Research · doi:10.1007/s00441-013-1740-5 · Cited by 69 · see citing works

Procollagen Lysyl Hydroxylase 2 Expression Is Regulated by an Alternative Downstream Transforming Growth Factor β-1 Activation Mechanism

Gjaltema, R. A. F., de Rond, S., Rots, M. G., & Bank, R. A. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.634311 · Cited by 66 · see citing works

Hydroxylysine-linked glycosides of human complement subcomponent C1q and various collagens

Shinkai, H., & Yonemasu, K. (1979) · Biochemical Journal · doi:10.1042/bj1770847 · Cited by 59 · see citing works

The human collagen beta(1-O)galactosyltransferase, GLT25D1, is a soluble endoplasmic reticulum localized protein

Liefhebber, J. M. P., Punt, S., Spaan, W. J. M., & van Leeuwen, H. C. (2010) · BMC Cell Biology · doi:10.1186/1471-2121-11-33 · Cited by 47 · see citing works

Novel signatures of cancer‐associated fibroblasts

Bozóky, B., Savchenko, A., Csermely, P., Korcsmaros, T. D., Dúl, Z., Pontén, F., Székely, L., & Klein, G. (2013) · International Journal of Cancer · doi:10.1002/ijc.28035 · Cited by 47 · see citing works

N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue

Nicastri, A., Gaspari, M., Sacco, R., Elia, L., Gabriele, C., Romano, R., Rizzuto, A., & Cuda, G. (2014) · Journal of Proteome Research · doi:10.1021/pr500647y · Cited by 45 · see citing works

Extracellular matrix protein ITGBL1 promotes ovarian cancer cell migration and adhesion through Wnt/PCP signaling and FAK/SRC pathway

Sun, L., Wang, D., Li, X., Zhang, L., Zhang, H., & Zhang, Y. (2016) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.03.053 · Cited by 40 · see citing works

An Activating Mutation Reveals a Second Binding Mode of the Integrin α2 I Domain to the GFOGER Motif in Collagens

Carafoli, F., Hamaia, S. W., Bihan, D. G., Hohenester, E., & Farndale, R. W. (2013) · PLoS ONE · doi:10.1371/journal.pone.0069833 · Cited by 39 · see citing works

Gene Expression Profiling of Peripheral Blood Leukocytes Shows Consistent Longitudinal Downregulation of TOMM40 and Upregulation of KIR2DL5A, PLOD1, and SLC2A8 Among Fast Progressors in Early Alzheimer's Disease

Chong, M. S., Goh, L. K., Lim, W. S., Chan, M., Tay, L. B. G., Chen, G., Feng, L., Ng, T. P., Tan, C. H., & Lee, T.-S. W. (2013) · Journal of Alzheimer s Disease · doi:10.3233/jad-121621 · Cited by 32 · see citing works

Identification of a microRNA (miR-663a) induced by ER stress and its target gene PLOD3 by a combined microRNome and proteome approach

Amodio, G., Sasso, E., DˈAmbrosio, C., Scaloni, A., Moltedo, O., Franceschelli, S., Zambrano, N., & Remondelli, P. (2016) · Cell Biology and Toxicology · doi:10.1007/s10565-016-9335-z · Cited by 30 · see citing works

Association of ECRG4 with PLK1, CDK4, PLOD1 and PLOD2 in esophageal squamous cell carcinoma.

Li, L., Wang, W., Li, X., & Gao, T. (2017) · PubMed Central · Cited by 30 · see citing works

Localization of the gene encoding a novel isoform of lysyl hydroxylase

Szpirer, C., Szpirer, J., Rivière, M., Vanvooren, P., Valtavaara, M., & Myllylä, R. (1997) · Mammalian Genome · doi:10.1007/s003359900549 · Cited by 28 · see citing works

Differential Effects of Bone Morphogenetic Protein-2 and Transforming Growth Factor-β1 on Gene Expression of Collagen-Modifying Enzymes in Human Adipose Tissue–Derived Mesenchymal Stem Cells

Knippenberg, M., Helder, M. N., Zandieh‐Doulabi, B., Bank, R. A., Wuisman, P. I. J. M., & Klein‐Nulend, J. (2009) · Tissue Engineering Part A · doi:10.1089/ten.tea.2007.0184 · Cited by 28 · see citing works

The IκB kinase inhibitor ACHP strongly attenuates TGF β1‐induced myofibroblast formation and collagen synthesis

Mia, M. M., & Bank, R. A. (2015) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12661 · Cited by 27 · see citing works

Kyphoscoliotic type of Ehlers-Danlos Syndrome (EDS VIA) in six Egyptian patients presenting with a homogeneous clinical phenotype

Abdalla, E. M., Rohrbach, M., Bürer, C., KRAENZLIN, M. E., El-Tayeby, H. M., El-Belbesy, M., Nabil, A., & Giunta, C. (2014) · European Journal of Pediatrics · doi:10.1007/s00431-014-2429-9 · Cited by 25 · see citing works

Lysyl Hydroxylase 3 Localizes to Epidermal Basement Membrane and Is Reduced in Patients with Recessive Dystrophic Epidermolysis Bullosa

Watt, S. A., Dayal, J. H. S., Wright, S. C., Riddle, M. J., Pourreyron, C., McMillan, J. R., Kimble, R. M., di Prisco, M., Gärtner, U., Warbrick, E., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0137639 · Cited by 25 · see citing works

Systems biology analysis of hepatitis C virus infection reveals the role of copy number increases in regions of chromosome 1q in hepatocellular carcinoma metabolism

Elsemman, I. E., Mardinoğlu, A., Shoaie, S., Soliman, T. H. A., & Nielsen, J. (2016) · Molecular BioSystems · doi:10.1039/c5mb00827a · Cited by 25 · see citing works

The Role of Leukocyte-Associated Ig-like Receptor-1 in Suppressing Collagen-Induced Arthritis

Kim, S., Easterling, E. R., Price, L., Smith, S. L., Coligan, J. E., Park, J. J., Brand, D. D., Rosloniec, E. F., Stuart, J. M., Kang, A. H., et al. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1700271 · Cited by 24 · see citing works

TUMOUR NECROSIS FACTOR α ENHANCES THE EXPRESSION OF HYDROXYL LYASE, CYTOPLASMIC ANTIPROTEINASE-2 AND A DUAL SPECIFICITY KINASE TTK IN HUMAN CHONDROCYTE-LIKE CELLS

Ah-Kim, H., Zhang, X., Islam, S., Sofi, J. I., Glickberg, Y., Malemud, C. J., Moskowitz, R. W., & Haqqi, T. M. (2000) · Cytokine · doi:10.1006/cyto.1999.0539 · Cited by 20 · see citing works

Alu-alu recombination results in duplication of seven exons in the lysyl hydroxylase gene from a patient with the type VI variant of Ehlers-Danlos syndrome

Pousi, B., Hautala, T., Heikkinen, J., PAJUNEN, L., Kivirikko, K. I., & Myllalä, R. (1994) · Matrix Biology · doi:10.1016/0945-053x(94)90130-9 · Cited by 17 · see citing works

Association of PLOD1 polymorphisms with bone mineral density in a population-based study of women from the UK

Tasker, P. N., Macdonald, H., Fraser, W. D., Reid, D. M., Ralston, S. H., & Albagha, O. (2006) · Osteoporosis International · doi:10.1007/s00198-006-0129-7 · Cited by 17 · see citing works

Expression analysis of genes involved in collagen cross‐linking and its regulation in traumatic anterior shoulder instability

Belangero, P. S., Leal, M. F., Cohen, C., de Figueiredo, E. A., Smith, M. D. A. C., Andreoli, C. V., Pochini, A. D. C., Ejnisman, B., & Cohen, M. (2015) · Journal of Orthopaedic Research® · doi:10.1002/jor.22984 · Cited by 16 · see citing works

Novel lysyl hydroxylase isoforms

Valtavaara, M. (1999) · Cited by 12 · see citing works

Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 2 Expression in Brain Arteriovenous Malformations and its Association with Brain Arteriovenous Malformation Size

Neyazi, B., Tanrikulu, L., Wilkens, L., Hartmann, C. J., Stein, K. P., Dumitru, C. A., & Sandalcioglu, I. E. (2017) · World Neurosurgery · doi:10.1016/j.wneu.2017.02.116 · Cited by 12 · see citing works

The Extracellular Matrix Signature in Vein Graft Disease

Kahle, B. K., Schmidtke, C., Hunzelmann, N., Bartels, C., Sievers, H. H., Steenbock, H., Reinhardt, D. P., & Brinckmann, J. (2015) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2015.11.014 · Cited by 10 · see citing works

Ehlers Danlos syndrome, kyphoscoliotic type due to Lysyl Hydroxylase 1 deficiency in two children without congenital or early onset kyphoscoliosis

van Dijk, F. S., Mancini, G. M. S., Maugeri, A., & Cobben, J. M. (2017) · European Journal of Medical Genetics · doi:10.1016/j.ejmg.2017.07.011 · Cited by 10 · see citing works

Kyphoscolitic type of Ehlers-Danlos syndrome with prenatal stroke

Zahed, M., Tosello, B., Coze, S., & Gire, C. (2017) · Indian Pediatrics · doi:10.1007/s13312-017-1054-x · Cited by 9 · see citing works

Concepts of extracellular matrix remodelling in tumour progression and metastasis

Winkler, J., Abisoye-Ogunniyan, A., Metcalf, K. J., & Werb, Z. (2020) · Nature Communications · doi:10.1038/s41467-020-18794-x · Cited by 2,296 · see citing works

The matrix in cancer

Cox, T. R. (2021) · Nature reviews. Cancer · doi:10.1038/s41568-020-00329-7 · Cited by 989 · see citing works

Vitamin C-Sources, Physiological Role, Kinetics, Deficiency, Use, Toxicity, and Determination

Doseděl, M., Jirkovský, E., Macáková, K., Krčmová, L., Javorská, L., Pourová, J., Mercolini, L., Remião, F., Nováková, L., Mladěnka, P., et al. (2021) · Nutrients · doi:10.3390/nu13020615 · Cited by 553 · see citing works

The Extracellular Matrix: Its Composition, Function, Remodeling, and Role in Tumorigenesis

Dzobo, K., & Dandara, C. (2023) · Biomimetics · doi:10.3390/biomimetics8020146 · Cited by 173 · see citing works

Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

He, J., Wei, X., Li, S., Liu, Y., Hu, H., Li, Z., Kuang, X.-H., Wang, L., Shi, X., Yuan, S., et al. (2018) · Cell Communication and Signaling · doi:10.1186/s12964-018-0309-z · Cited by 123 · see citing works

CREB3L1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by remodeling the tumor microenvironment

Pan, Z., Xu, T., Bao, L., Hu, X., Jin, T., Chen, J., Chen, J., Qian, Y., Lu, X., li, L., et al. (2022) · Molecular Cancer · doi:10.1186/s12943-022-01658-x · Cited by 120 · see citing works

Collagen biology making inroads into prognosis and treatment of cancer progression and metastasis

Cavaco, A. C. M., Dâmaso, S., Casimiro, S., & Costa, L. (2020) · Cancer and Metastasis Reviews · doi:10.1007/s10555-020-09888-5 · Cited by 101 · see citing works

Cancer-Associated Fibroblasts in the Hypoxic Tumor Microenvironment

Kim, I., Choi, S., Yoo, S., Lee, M., & Kim, I. (2022) · Cancers · doi:10.3390/cancers14143321 · Cited by 98 · see citing works

Collagen Remodeling along Cancer Progression Providing a Novel Opportunity for Cancer Diagnosis and Treatment

Song, K., Yu, Z., Zu, X., Li, G., Hu, Z., & Xue, Y. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231810509 · Cited by 91 · see citing works

The complex dynamics of myocardial interstitial fibrosis in heart failure. Focus on collagen cross-linking

González, A., López, B., Ravassa, S., José, G. S., & Dı́ez, J. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2019.06.001 · Cited by 83 · see citing works

Targeting type I collagen for cancer treatment

Shi, R., Zhang, Z., Zhu, A.-K., Xiong, X., Zhang, J., Xu, J., Sy, M., & Li, C. (2022) · International Journal of Cancer · doi:10.1002/ijc.33985 · Cited by 71 · see citing works

Proteomic signatures of 16 major types of human cancer reveal universal and cancer-type-specific proteins for the identification of potential therapeutic targets

Zhou, Y., Lih, T. M., Pan, J., Höti, N., Dong, M., Cao, L., Hu, Y., Cho, K.-C., Chen, S., Eguez, R. V., et al. (2020) · Journal of Hematology & Oncology · doi:10.1186/s13045-020-01013-x · Cited by 70 · see citing works

The effect of a novel glycolysis-related gene signature on progression, prognosis and immune microenvironment of renal cell carcinoma

Xu, F., Guan, Y., Li, X., Huang, S., Gao, K., Yang, Z., & Chong, T. (2020) · BMC Cancer · doi:10.1186/s12885-020-07702-7 · Cited by 68 · see citing works

Fibroblast heterogeneity and its impact on extracellular matrix and immune landscape remodeling in cancer

Yamauchi, M., Gibbons, D. L., Zong, C. C., Fradette, J. J., Bota‐Rabassedas, N., & Kurie, J. M. (2020) · Matrix Biology · doi:10.1016/j.matbio.2020.05.001 · Cited by 66 · see citing works

Dynamically remodeled hepatic extracellular matrix predicts prognosis of early-stage cirrhosis

Wu, Y., Cao, Y., Xu, K., Zhu, Y., Qiao, Y., Wu, Y., Chen, J., Li, C., Zeng, R., & Ge, G. (2021) · Cell Death and Disease · doi:10.1038/s41419-021-03443-y · Cited by 65 · see citing works

Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling

Wang, Z., Shi, Y., Ying, C., Jiang, Y., & Hu, J. (2021) · Oncogene · doi:10.1038/s41388-020-01635-y · Cited by 62 · see citing works

PLOD2 promotes aerobic glycolysis and cell progression in colorectal cancer by upregulating HK2

Du, W., Liu, N., Zhang, Y., Liu, X., Yang, Y., Chen, W., & He, Y. (2019) · Biochemistry and Cell Biology · doi:10.1139/bcb-2019-0256 · Cited by 58 · see citing works

Recovery of Bioactive Compounds from Marine Organisms: Focus on the Future Perspectives for Pharmacological, Biomedical and Regenerative Medicine Applications of Marine Collagen

Rigogliuso, S., Campora, S., Notarbartolo, M., & Ghersi, G. (2023) · Molecules · doi:10.3390/molecules28031152 · Cited by 58 · see citing works

METTL16 Promotes Translation and Lung Tumorigenesis by Sequestering Cytoplasmic eIF4E2

Wang, F., Zhang, J., Lin, X., Yang, L., Zhou, Q., Mi, X., Li, Q., Wang, S., Li, D., Liu, X., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2023.112150 · Cited by 57 · see citing works

Overexpressing PLOD family genes predict poor prognosis in gastric cancer

Li, S., Lian, Y., Huang, Y., Huang, Y., & Xiao, J. (2019) · Journal of Cancer · doi:10.7150/jca.35763 · Cited by 55 · see citing works

DDX5 inhibits hyaline cartilage fibrosis and degradation in osteoarthritis via alternative splicing and G-quadruplex unwinding

Liu, Q., Han, M., Wu, Z., Fu, W., Ji, J., Liang, Q., Tan, M., Zhai, L., Gao, J., Shi, D., et al. (2024) · Nature Aging · doi:10.1038/s43587-024-00624-0 · Cited by 54 · see citing works

Spatially Resolved Deconvolution of the Fibrotic Niche in Lung Fibrosis

Eyres, M., Bell, J. A., Davies, E. R., Fabre, A., Alzetani, A., Jogai, S., Marshall, B. G., Johnston, D. A., Xu, Z., Fletcher, S., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111230 · Cited by 53 · see citing works

Aberrantly expressed PLOD 1 promotes cancer aggressiveness in bladder cancer: a potential prognostic marker and therapeutic target

Yamada, Y., Kato, M., Arai, T., Sanada, H., Uchida, A., Misono, S., Sakamoto, S., Komiya, A., Ichikawa, T., & Seki, N. (2019) · Molecular Oncology · doi:10.1002/1878-0261.12532 · Cited by 52 · see citing works

Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy

Koedoot, E., Wolters, L., Smid, M., Stoilov, P., Burger, G. A., Herpers, B., Yan, K., Price, L., Martens, J. W. M., Dévédec, S. E. L., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-86664-7 · Cited by 50 · see citing works

The HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair

Kang, H., Strong, A. L., Sun, Y., Guo, L., Juan, C., Bancroft, A. C., Choi, J. H., Pagani, C. A., Fernandes, A. A., Woodard, M., et al. (2024) · Bone Research · doi:10.1038/s41413-024-00320-0 · Cited by 46 · see citing works

The Extracellular Matrix: Composition, Function, Remodeling and Its Role in TumorigenesisPreprint

Dzobo, K., & Dandara, C. (2023) · Preprints.org · doi:10.20944/preprints202301.0555.v1 · Cited by 45 · see citing works

Identification of an EMT-Related Gene Signature for Predicting Overall Survival in Gastric Cancer

Dai, W., Xiao, Y., Tang, W., Li, J., Hong, L., Zhang, J., Pei, M., Lin, J., Liu, S., Wu, X., et al. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.661306 · Cited by 42 · see citing works

The PLOD2/succinate axis regulates the epithelial–mesenchymal plasticity and cancer cell stemness

Tong, Y., Qi, Y., Xiong, G., Li, J., Scott, T. L., Chen, J., He, D., Li, L., Wang, C., Lane, A. N., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2214942120 · Cited by 43 · see citing works

Identification of PLOD Family Genes as Novel Prognostic Biomarkers for Hepatocellular Carcinoma

Yang, B., Zhao, Y., Wang, L., Zhao, Y., Wei, L., Chen, D., & Chen, Z. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.01695 · Cited by 41 · see citing works

PLOD1 promotes cell growth and aerobic glycolysis by regulating the SOX9/PI3K/Akt/mTOR signaling pathway in gastric cancer

Zhang, Y., Wu, Y., & Su, X. (2021) · Frontiers in Bioscience-Landmark · doi:10.52586/4946 · Cited by 41 · see citing works

Tumor-derived CTF1 (cardiotrophin 1) is a critical mediator of stroma-assisted and autophagy-dependent breast cancer cell migration, invasion and metastasis

Akkoç, Y., Dalcı, K., Schüller, H. E. K., Erbil-Bilir, S., Yalav, O., Sakman, G., Çelik, F., Arıkan, S., Zeybek, Ü., Ergin, M., et al. (2022) · Autophagy · doi:10.1080/15548627.2022.2090693 · Cited by 40 · see citing works

Global Gene Expression Analysis Identifies Age-Related Differences in Knee Joint Transcriptome during the Development of Post-Traumatic Osteoarthritis in Mice

Sebastian, A., Murugesh, D. K., Mendez, M. E., Hum, N. R., Rios‐Arce, N. D., McCool, J. L., Christiansen, B., & Loots, G. G. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21010364 · Cited by 40 · see citing works

Colorectal Cancer Stem Cells in the Progression to Liver Metastasis

González-Villarreal, C. A., Quiroz-Reyes, A. G., Islas, J. F., & Garza-Treviño, E. N. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.01511 · Cited by 38 · see citing works

Scaffold-free 3D cell culture of primary skin fibroblasts induces profound changes of the matrisome

Vu, B., Souza, G. R., & Dengjel, J. (2021) · Matrix Biology Plus · doi:10.1016/j.mbplus.2021.100066 · Cited by 37 · see citing works

Apelin promotes osteosarcoma metastasis by upregulating PLOD2 expression via the Hippo signaling pathway and hsa_circ_0000004/miR-1303 axis

Trang, N. T. N., Lai, C.-Y., Tsai, H., Huang, Y., Liu, S., Tsai, C., Fong, Y., Tzeng, H.-E., & Tang, C. (2022) · International Journal of Biological Sciences · doi:10.7150/ijbs.77688 · Cited by 34 · see citing works

Superenhancer drives a tumor-specific splicing variant of MARCO to promote triple-negative breast cancer progression

Yang, Y., Jin, X., Li, Q., Chen, Y., Chen, F., Zhang, H., Su, Y., Xiao, Y., Di, G., Jiang, Y., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2207201119 · Cited by 34 · see citing works

METTL3 facilitates renal cell carcinoma progression by PLOD2 m6A-methylation under prolonged hypoxia

Chen, Y., He, Y., Li, Z., Zhang, N., Zhou, C., He, X., & Xue, D. (2024) · Cell Death and Disease · doi:10.1038/s41419-023-06411-w · Cited by 32 · see citing works

The cellular-centered view of hypoxia tumor microenvironment: Molecular mechanisms and therapeutic interventions

Zhang, T., Lv, Q., & Jin, W. (2024) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2024.189137 · Cited by 34 · see citing works

PLOD1 Is a Prognostic Biomarker and Mediator of Proliferation and Invasion in Osteosarcoma

Jiang, H., Guo, W., Yuan, S., & Song, L. (2020) · BioMed Research International · doi:10.1155/2020/3418398 · Cited by 28 · see citing works

Notch regulates vascular collagen IV basement membrane through modulation of lysyl hydroxylase 3 trafficking

Gross, S. J., Webb, A. M., Peterlin, A. D., Durrant, J., Judson, R. J., Raza, Q., Kitajewski, J., & Kushner, E. J. (2021) · Angiogenesis · doi:10.1007/s10456-021-09791-9 · Cited by 31 · see citing works

3D hydrogel-based microcapsules as an in vitro model to study tumorigenicity, cell migration and drug resistance

Ertekin, Ö., Monavari, M., Krüger, R., Fuentes‐Chandía, M., Parma, B., Letort, G., Tripal, P., Boccaccini, A. R., Bosserhoff, A., Ceppi, P., et al. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.02.010 · Cited by 31 · see citing works

PLOD2 promotes colorectal cancer progression by stabilizing USP15 to activate the AKT/mTOR signaling pathway

Lan, J., Zhang, S., Zheng, L., Long, X., Chen, J., Liu, X., Zhou, M., & Zhou, J. (2023) · Cancer Science · doi:10.1111/cas.15851 · Cited by 30 · see citing works

Lysyl hydroxylase LH1 promotes confined migration and metastasis of cancer cells by stabilizing Septin2 to enhance actin network

Yang, Z., Zhou, L., Si, T., Chen, S., Liu, C., Ng, K. K., Wang, Z., Chen, Z., Qiu, C., Liu, G., et al. (2023) · Molecular Cancer · doi:10.1186/s12943-023-01727-9 · Cited by 28 · see citing works

High-throughput screening identified miR-7-2-3p and miR-29c-3p as metastasis suppressors in gallbladder carcinoma

Lu, K., Feng, F., Yang, Y., Liu, K., Duan, J., Liu, H., Yang, J., Wu, M., Liu, C., & Chang, Y. (2019) · Journal of Gastroenterology · doi:10.1007/s00535-019-01627-0 · Cited by 27 · see citing works

Understanding Mechanisms Underlying Non-Alcoholic Fatty Liver Disease (NAFLD) in Mental Illness: Risperidone and Olanzapine Alter the Hepatic Proteomic Signature in Mice

Rostama, B., Beauchemin, M., Bouchard, C., Bernier, E., Vary, C., May, M. A., & Houseknecht, K. L. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249362 · Cited by 27 · see citing works

Role of Collagen Regulators in Cancer Treatment: A Comprehensive Review

Angre, T. D., Kumar, A., Singh, A. K., Thareja, S., & Kumar, P. (2022) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/1871520622666220501162351 · Cited by 27 · see citing works

DOWEL PLACEMENT TOLERANCES FOR CONCRETE PAVEMENTS

Tayabji, S. D. (1986) · Transportation Research Record Journal of the Transportation Research Board · Cited by 27 · see citing works

Association between pectus excavatum and congenital genetic disorders: A systematic review and practical guide for the treating physician

Billar, R. J., Manoubi, W., Kant, S. G., Wijnen, R. M. H., Demirdas, S., & Schnater, J. M. (2021) · Journal of Pediatric Surgery · doi:10.1016/j.jpedsurg.2021.04.016 · Cited by 27 · see citing works

Therapeutic and diagnostic targeting of fibrosis in metabolic, proliferative and viral disorders

Sofias, A. M., Lorenzi, F. D., Peña, Q., Shalmani, A. A., Vucur, M., Wang, J., Kiessling, F. M., Shi, Y., Consolino, L., Storm, G., et al. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.113831 · Cited by 27 · see citing works

Genetic and Epigenetic Aspects of Skin Collagen Fiber Turnover and Functioning

Потекаев, Н. Н., Borzykh, O. B., Medvedev, G. V., Петрова, М. М., Gavrilyuk, O. A., Karpova, E. I., Trefilova, V. V., Demina, O. M., Popova, T. E., & Shnayder, N. A. (2021) · Cosmetics · doi:10.3390/cosmetics8040092 · Cited by 26 · see citing works

CDH4 inhibits ferroptosis in oral squamous cell carcinoma cells

Xie, J. W., Lan, T., Zheng, D., Ding, L.-C., & Lu, Y. (2023) · BMC Oral Health · doi:10.1186/s12903-023-03046-3 · Cited by 26 · see citing works

Growth factor and macromolecular crowding supplementation in human tenocyte culture

Tsiapalis, D., Kearns, S. R., Kelly, J. L., & Zeugolis, D. I. (2021) · Biomaterials and Biosystems · doi:10.1016/j.bbiosy.2021.100009 · Cited by 25 · see citing works

Collagen production and niche engineering: A novel strategy for cancer cells to survive acidosis in DCIS and evolve

Damaghi, M., Byrne, S., Xu, L., Tafreshi, N., Fang, B., Koomen, J. M., Karolak, A. M., Chen, T., Johnson, J., Gallant, N. D., et al. (2020) · Evolutionary Applications · doi:10.1111/eva.13075 · Cited by 25 · see citing works

Risk stratification for bladder cancer: Biomarkers of inflammation and immune activation

Nabavizadeh, R., Bobrek, K., & Master, V. A. (2020) · Urologic Oncology Seminars and Original Investigations · doi:10.1016/j.urolonc.2020.04.006 · Cited by 24 · see citing works

Collagen hydroxylysine glycosylation: non-conventional substrates for atypical glycosyltransferase enzymes

Giorgi, F. D., Fumagalli, M., Scietti, L., & Forneris, F. (2021) · Biochemical Society Transactions · doi:10.1042/bst20200767 · Cited by 24 · see citing works

Proteomics profiling of colorectal cancer progression identifies PLOD2 as a potential therapeutic target

Shao, Y., Xu, K., Zheng, X. E., Zhou, B., Zhang, X., Wang, L., Sun, Y., Li, D., Chen, T., Wang, J., et al. (2021) · 癌症：英文版 · doi:10.1002/cac2.12240 · Cited by 24 · see citing works

PLOD2 high expression associates with immune infiltration and facilitates cancer progression in osteosarcoma

Wang, Z., Fan, G., Zhu, H., Yu, L., She, D., Wei, Y., Huang, J., Li, T., Zhan, S., Zhou, S., et al. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.980390 · Cited by 25 · see citing works

PLODs are overexpressed in ovarian cancer and are associated with gap junctions via connexin 43

Guo, T., Gu, C., Li, B., & Xu, C. (2021) · Laboratory Investigation · doi:10.1038/s41374-021-00533-5 · Cited by 22 · see citing works

The Role of a Proprotein Convertase Inhibitor in Reactivation of Tumor-Associated Macrophages and Inhibition of Glioma Growth

Rose, M., Duhamel, M., Aboulouard, S., Kobeissy, F. H., Rhun, E. L., Desmons, A., Tierny, D., Fournier, I., Rodet, F., & Salzet, M. (2020) · Molecular Therapy — Oncolytics · doi:10.1016/j.omto.2020.03.005 · Cited by 22 · see citing works

Transcripto‐based network analysis reveals a model of gene activation in tongue squamous cell carcinomas

Zeng, H., Li, H., Zhao, Y., Chen, L., & Ma, X. (2019) · Head & Neck · doi:10.1002/hed.25952 · Cited by 21 · see citing works

Identification and Validation of PLOD2 as an Adverse Prognostic Biomarker for Oral Squamous Cell Carcinoma

Sun, Y., Wang, S., Zhang, X., Wu, Z., Li, Z., Ding, Z., Huang, X., Chen, S., Jing, Y., Zhang, X., et al. (2021) · Biomolecules · doi:10.3390/biom11121842 · Cited by 21 · see citing works

A multi-omic analysis of orange-spotted grouper larvae infected with nervous necrosis virus identifies increased adhesion molecules and collagen synthesis in the persistent state

Ge, H. M., Lin, K., Zhou, C., Lin, Q., Zhang, Z., Wu, J., Zheng, L., Yang, Q., Wu, S., Chen, W., et al. (2020) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2020.01.056 · Cited by 21 · see citing works

Vitamin C Differentially Impacts the Serum Proteome Profile in Female and Male Mice

Aumailley, L., Bourassa, S., Gotti, C., Droit, A., & Lebel, M. (2021) · Journal of Proteome Research · doi:10.1021/acs.jproteome.1c00542 · Cited by 20 · see citing works

Overexpressing PLOD Family Genes Predict Poor Prognosis in Pancreatic Cancer

Zhang, J., Tian, Y. Z., Mo, S. J., & Fu, X. F. (2022) · International Journal of General Medicine · doi:10.2147/ijgm.s341332 · Cited by 19 · see citing works

Integrated Profiling Identifies PLOD3 as a Potential Prognostic and Immunotherapy Relevant Biomarker in Colorectal Cancer

Shi, J., Bao, M., Wang, W.-F., Wu, X., Li, Y., Changdong, Z., & Liu, W. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.722807 · Cited by 20 · see citing works

SARS-CoV-2 accessory proteins involvement in inflammatory and profibrotic processes through IL11 signaling

López-Ayllón, B. D., de Lucas‐Rius, A., Mendoza‐García, L., García‐García, T., Fernández‐Rodríguez, R., Suárez-Cárdenas, J. M., Santos, F. M., Corrales, F. J., Redondo, N., Pedrucci, F., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1220306 · Cited by 19 · see citing works

Quantitative Proteomic Analysis of Cervical Cancer Tissues Identifies Proteins Associated With Cancer Progression

Ramírez-Torres, A., Gil, J., Contreras, S., RAMÍREZ, G., Valencia-González, H. A., Salazar-Bustamante, E., Gómez‐Caudillo, L., García-Carrancá, A. M., & Encarnación‐Guevara, S. (2022) · Cancer Genomics & Proteomics · doi:10.21873/cgp.20317 · Cited by 19 · see citing works

Procollagen-lysine, 2-oxoglutarate 5-dioxygenases 1, 2, and 3 are potential prognostic indicators in patients with clear cell renal cell carcinoma

Xu, W., Xu, Y., Wang, J., Tian, X., Wu, J., Wan, F., Wang, H., Qu, Y.-Y., Zhang, H., & Ye, D. (2019) · Aging · doi:10.18632/aging.102206 · Cited by 19 · see citing works

PLOD3 contributes to HER-2 therapy resistance in gastric cancer through FoxO3/Survivin pathway

Chen, Y., Ye, B., Wang, C., Nie, Y., Qin, J., & Shen, Z. (2022) · Cell Death Discovery · doi:10.1038/s41420-022-01103-4 · Cited by 18 · see citing works

Quantitative Proteomics Identifies Secreted Diagnostic Biomarkers as well as Tumor-Dependent Prognostic Targets for Clear Cell Renal Cell Carcinoma

Şentürk, A., Sahin, A. T., Armutlu, A., Kiremit, M. C., Acar, Ö., Erdem, S., Bağbudar, S., Esen, T., Tunçbağ, N., & Özlü, N. (2021) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-21-0004 · Cited by 18 · see citing works

Identification of PLOD3 and LRRN3 as potential biomarkers for Parkinson’s disease based on integrative analysis

Guo, X., Hu, W., Gao, Z., Yang, F., Wu, Q., & Li, W. (2023) · npj Parkinson s Disease · doi:10.1038/s41531-023-00527-8 · Cited by 17 · see citing works

PLOD2 increases resistance of gastric cancer cells to 5-fluorouracil by upregulating BCRP and inhibiting apoptosis

Wang, X., Guo, J., Dai, M., Wang, T., Yang, T., Xiao, X., Tang, Q., Zhang, L., & Jia, L. (2020) · Journal of Cancer · doi:10.7150/jca.41828 · Cited by 17 · see citing works

A Novel Prognostic Signature for Survival Prediction and Immune Implication Based on SARS-CoV-2–Related Genes in Kidney Renal Clear Cell Carcinoma

Huang, Y., Chen, S., Xiao, L., Qin, W., Li, L., Wang, Y., Ma, L., & Yuan, X. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.744659 · Cited by 17 · see citing works

COLGALT2 is overexpressed in ovarian cancer and interacts with PLOD3

Guo, T., Li, B., Kang, Y., Gu, C., Fang, F., Chen, X., Liu, X., Guo, L., Feng, C., & Xu, C. (2021) · Clinical and Translational Medicine · doi:10.1002/ctm2.370 · Cited by 17 · see citing works

The IRE1α–XBP1s Arm of the Unfolded Protein Response Activates N-Glycosylation to Remodel the Subepithelial Basement Membrane in Paramyxovirus Infection

Zhao, Y., Qiao, D., Skibba, M. E., & Brasier, A. R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23169000 · Cited by 16 · see citing works

Correlation of Matrisome-Associatted Gene Expressions with LOX Family Members in Astrocytomas Stratified by IDH Mutation Status

Laurentino, T. D. S., Soares, R. D. S., Marie, S. K. N., & Oba‐Shinjo, S. M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179507 · Cited by 16 · see citing works

Procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 promotes collagen cross-linking and ECM stiffening to induce liver fibrosis

Yue, W., Zhang, H., Gao, Y., Ding, J., Xue, R., Dong, C., Liu, F., Yang, L., Yang, L., & Li, L. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2024.167205 · Cited by 16 · see citing works

Identification of metabolism-associated genes and construction of a prognostic signature in bladder cancer

Shen, C., Liu, J., Wang, L., Liang, Z., Niu, H., & Wang, Y. (2020) · Cancer Cell International · doi:10.1186/s12935-020-01627-8 · Cited by 15 · see citing works

Introduction of a Cys360Tyr Mutation in ANO5 Creates a Mouse Model for Gnathodiaphyseal Dysplasia

Li, H., Wang, X., Chen, E., Liu, X., Ma, X., Miao, C., Tian, Z., Dong, R., & Hu, Y. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4481 · Cited by 15 · see citing works

SIRT6 deficiency causes ovarian hypoplasia by affecting Plod1 ‐related collagen formation

Li, L., Hua, R., Hu, K., Chen, H., Yin, Y., Shi, X., Peng, K., Huang, Q., Qiu, Y., Li, X., et al. (2023) · Aging Cell · doi:10.1111/acel.14031 · Cited by 15 · see citing works

Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase Family: Novel Prognostic Biomarkers and Tumor Microenvironment Regulators for Lower-Grade Glioma

Gong, S., Wu, C., Köhler, F., Meixensberger, J., Schopow, N., & Kallendrusch, S. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.838548 · Cited by 16 · see citing works

Deciphering the divergent transcriptomic landscapes of cervical cancer cells grown in 3D and 2D cell culture systems

Kumar, R., Iden, M., Tsaih, S., Schmidt, R., Ojesina, A. I., & Rader, J. S. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1413882 · Cited by 14 · see citing works

Characterization of a cancer-associated Epstein-Barr virus EBNA1 variant reveals a novel interaction with PLOD1 and PLOD3

Shire, K., Marcon, E., Greenblatt, J. F., & Frappier, L. (2021) · Virology · doi:10.1016/j.virol.2021.07.009 · Cited by 14 · see citing works

iTRAQ‐Based Quantitative Proteomic Analysis Strengthens Transcriptomic Subtyping of Triple‐Negative Breast Cancer Tumors

Jézéquel, P., Guette, C., Lasla, H., Gouraud, W., Boissard, A., Guérin‐Charbonnel, C., & Campone, M. (2019) · PROTEOMICS · doi:10.1002/pmic.201800484 · Cited by 14 · see citing works

Knockdown of PLOD3 suppresses the malignant progression of renal cell carcinoma via reducing TWIST1 expression

Xie, D., Li, J., Wei, S., Pan, Q., Ji, H., Su, J., Du, N., & Zhang, X. (2020) · Molecular and Cellular Probes · doi:10.1016/j.mcp.2020.101608 · Cited by 13 · see citing works

Loss of talin in cardiac fibroblasts results in augmented ventricular cardiomyocyte hypertrophy in response to pressure overload

Noll, N. A., Riley, L. A., Moore, C. S., Zhong, L., Bersi, M. R., West, J. D., Zent, R., & Merryman, W. D. (2022) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00632.2021 · Cited by 13 · see citing works

Berberine Attenuates Cell Motility via Inhibiting Inflammation-Mediated Lysyl Hydroxylase-2 and Glycolysis

Du, Y., Khan, M. B., Fang, N., Ma, F., Du, H., Tan, Z., Wang, H., Yin, S., & Wei, X. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.856777 · Cited by 13 · see citing works

Comprehensive Analysis of the Expression, Prognosis, and Biological Significance of PLOD Family in Bladder Cancer

Chen, R., Jiang, M., Hu, B., Fu, B., & Sun, T. (2023) · International Journal of General Medicine · doi:10.2147/ijgm.s399875 · Cited by 13 · see citing works

Regulation of EBNA1 protein stability and DNA replication activity by PLOD1 lysine hydroxylase

Dheekollu, J., Wiedmer, A., Soldan, S. S., Castro-Muñoz, L. J., Chen, C., Tang, H., Speicher, D. W., & Lieberman, P. M. (2023) · PLoS Pathogens · doi:10.1371/journal.ppat.1010478 · Cited by 13 · see citing works

Oxidative stress‐induced changes in wooden breast and mitigation strategies: A review

Wang, Y., Li, B., Jian, C., Gagaoua, M., Estévez, M., Puolanne, E., & Ertbjerg, P. (2025) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.70148 · Cited by 13 · see citing works

Collagen IV biosynthesis: Intracellular choreography of post-translational modifications

Ishikawa, Y., Lennon, R., Forneris, F., Myllyharju, J., & Salo, A. M. (2025) · Matrix Biology · doi:10.1016/j.matbio.2025.07.002 · Cited by 13 · see citing works

Bottom up proteomics reveals novel differentiation proteins in neuroblastoma cells treated with 13-cis retinoic acid

Halakos, E. G., Connell, A. J., Glazewski, L., Wei, S., & Mason, R. W. (2019) · Journal of Proteomics · doi:10.1016/j.jprot.2019.103491 · Cited by 13 · see citing works

A Human Pan-Cancer System Analysis of Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3)

Gong, S., Duan, Y., Wu, C., Osterhoff, G., Schopow, N., & Kallendrusch, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22189903 · Cited by 13 · see citing works

Circular RNA circPLOD2 regulates pericyte function by targeting the transcription factor KLF4

Glaser, S.-F., Brezski, A., Baumgarten, N., Klangwart, M., Heumüller, A. W., Maji, R. K., Leisegang, M. S., Guenther, S., Zehendner, C. M., John, D., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112824 · Cited by 13 · see citing works

Context Matters: Response Heterogeneity to Collagen-Targeting Approaches in Desmoplastic Cancers

Fuller, A. M., & Eisinger‐Mathason, T. S. K. (2022) · Cancers · doi:10.3390/cancers14133132 · Cited by 13 · see citing works

Identification of Glucocorticoid Receptor Target Genes That Potentially Inhibit Collagen Synthesis in Human Dermal Fibroblasts

Choi, D., Kang, W., Park, S., Son, B., & Park, T. (2023) · Biomolecules · doi:10.3390/biom13060978 · Cited by 12 · see citing works

The relationship between PLOD1 expression level and glioma prognosis investigated using public databases

Tian, L., Zhou, H., Wang, G., Wang, W. Y., Li, Y., & Xue, X. (2021) · PeerJ · doi:10.7717/peerj.11422 · Cited by 12 · see citing works

Overexpressing PLOD Family Genes Predict Poor Prognosis in Pancreatic Cancer

Zhang, J., Tian, Y., Mo, S., & Fu, X. (2022) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 12 · see citing works

Exploring links between 2‐oxoglutarate‐dependent oxygenases and Alzheimer's disease

Liu, H., Xie, Y., Wang, X., Abboud, M. I., Ma, C., Ge, W., & Schofield, C. J. (2022) · Alzheimer s & Dementia · doi:10.1002/alz.12733 · Cited by 11 · see citing works

Single-cell RNA seq identifies Plg-RKT-PLG as signals inducing phenotypic transformation of scar-associated macrophage in liver fibrosis

Yang, Y., Li, W., Liu, C., Liu, J., Yang, L., Yue, W., Yang, L., Xue, R., Zhang, K., Zhang, H., et al. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166754 · Cited by 12 · see citing works

PLOD2 in cancer research

Du, H., Pang, M., Hou, X., Yuan, S., & Sun, L. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.04.023 · Cited by 106 · see citing works

The role of PLOD2 in cancer metastasis

Bronts, S. (2019)

PLOD2 regulated by transcription factor FOXA1 promotes metastasis in NSCLC

Du, H., Chen, Y., Hou, X., Huang, Y., Wei, X., Yu, X., Feng, S. L., Wu, Y., Zhan, M., Shi, X., et al. (2017) · Cell Death and Disease · doi:10.1038/cddis.2017.553 · Cited by 97 · see citing works

The PLOD2 promotes tumor progression in colorectal cancer through the PI3K-AKT pathwayPreprint

Chen, D., Zhang, M., Zhou, Y., Zhu, H., Deng, Z., Li, O., & Zhou, Y. (2024) · Research Square · doi:10.21203/rs.3.rs-5266104/v1

Podoplanin: a novel regulator of tumor invasion and metastasis

Dang, Q., Liu, J., Li, J., & Sun, Y. (2014) · Medical Oncology · doi:10.1007/s12032-014-0024-6 · Cited by 42 · see citing works