Roles of PLODs in Collagen Synthesis and Cancer Progression

Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin

Aziz, J., Shezali, H., Radzi, Z., Yahya, N. A., Abu Kassim, N. H., Czernuszka, J., & Rahman, M. T. (2016) · Skin Pharmacology and Physiology · doi:10.1159/000447017 · Cited by 7,323

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

Levental, K. R., Yu, H., Kass, L., Lakins, J. N., Egeblad, M., Erler, J. T., Fong, S. F. T., Csiszar, K., Giaccia, A., Weninger, W., et al. (2009) · Cell · doi:10.1016/j.cell.2009.10.027 · Cited by 4,101

Tumour-educated macrophages promote tumour progression and metastasis

Pollard, J. W. (2004) · Nature reviews. Cancer · doi:10.1038/nrc1256 · Cited by 3,414

Collagen reorganization at the tumor-stromal interface facilitates local invasion

Provenzano, P. P., Eliceiri, K. W., Campbell, J. M., Inman, D. R., White, J. G., & Keely, P. J. (2006) · BMC Medicine · doi:10.1186/1741-7015-4-38 · Cited by 1,804

Collagen density promotes mammary tumor initiation and progression

Provenzano, P. P., Inman, D. R., Eliceiri, K. W., Knittel, J. G., Yan, L., Rueden, C., White, J. G., & Keely, P. J. (2008) · BMC Medicine · doi:10.1186/1741-7015-6-11 · Cited by 1,394

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

Conklin, M. W., Eickhoff, J. C., Riching, K. M., Pehlke, C. A., Eliceiri, K. W., Provenzano, P. P., Friedl, A., & Keely, P. J. (2011) · American Journal Of Pathology · doi:10.1016/j.ajpath.2010.11.076 · Cited by 1,321

Dynamic interplay between the collagen scaffold and tumor evolution

Egeblad, M., Rasch, M. G., & Weaver, V. M. (2010) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2010.08.015 · Cited by 931

Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus

Saito, M., & Marumo, K. (2009) · Osteoporosis International · doi:10.1007/s00198-009-1066-z · Cited by 914

JMJD6 Dysfunction Due to Iron Deficiency in Preeclampsia Disrupts Fibronectin Homeostasis Resulting in Diminished Trophoblast Migration

Alahari, S., Farrell, A., Ermini, L., Park, C., Sallais, J., Roberts, S., Gillmore, T., Litvack, M. L., Post, M., & Caniggia, I. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.652607 · Cited by 12

PLOD1 acts as a tumor promoter in glioma via activation of the HSF1 signaling pathway

Yuan, B., Xu, Y., & Zheng, S. (2021) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-021-04289-w · Cited by 12

Microenvironmental and Molecular Pathways Driving Dormancy Escape in Bone Metastases

Bakir, M. A., Dabaliz, A., Dawalibi, A., & Mohammad, K. S. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262411893 · Cited by 13

Proteome-Wide Discovery of Degradable Proteins Using Bifunctional Molecules

Forrest, I., Conway, L. P., Gathmann, C., Jadhav, A. M., Chiu, T.-Y., Chaheine, C. M., Estrada, M. A., Shrestha, A., Sarris, K., Reitsma, J. M., et al. (2025) · ACS Central Science · doi:10.1021/acscentsci.5c01594 · Cited by 12

An in vitro model to evaluate the properties of matrices produced by fibroblasts from osteogenesis imperfecta and Ehlers-Danlos Syndrome patients

Micha, D., Pals, G., Smit, T. H., & Ghazanfari, S. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.09.081 · Cited by 11

Comprehensive analysis of PLOD family members in low-grade gliomas using bioinformatics methods

Zhao, Y., Zhang, X., & Yao, J. (2021) · PLoS ONE · doi:10.1371/journal.pone.0246097 · Cited by 10

Collagen-Heparin-FGF2-VEGF Scaffolds Induce a Regenerative Gene Expression Profile in a Fetal Sheep Wound Model

Gansevoort, M., Oostendorp, C., Bouwman, L. F., Tiemessen, D. M., Geutjes, P. J., Feitz, W., Kuppevelt, T. H. V., & Daamen, W. F. (2024) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-024-00667-9 · Cited by 10

Dysregulated S100A9 Expression Impairs Matrix Deposition in Chronic Wounds

Franz, S., Torregrossa, M., Anderegg, U., Ertel, A., & Saalbach, A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25189980 · Cited by 10

Decellularized extracellular matrix from bovine ovarian tissue maintains the protein composition of the native matrisome

León-Félix, C. M., Ouni, E., Herinckx, G., Vertommen, D., Amorim, C. A., & Lucci, C. M. (2024) · Journal of Proteomics · doi:10.1016/j.jprot.2024.105347 · Cited by 11

Increasing collagen synthesis in fibroblasts: The roles of PCL microspheres and the SAMD11–PLOD1 axis in skin rejuvenation

Cao, M., Li, T., Zhang, Y., Zhou, L., Wu, S., Zhou, H., Ge, Y., Zou, Y., & Luo, S. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2025.119931 · Cited by 13

Profiling extra cellular matrix associated proteome of human fetal nucleus pulposus in search for regenerative targets

Rajasekaran, S., Thangavel, C., Djuric, N., Raveendran, M., Soundararajan, D. C. R., Nayagam, S. M., Matchado, M. S., Anand, K. S. S. V., & Venkateshwaran, K. (2021) · Scientific Reports · doi:10.1038/s41598-021-97620-w · Cited by 10

A Robust Metabolic Enzyme-Based Prognostic Signature for Head and Neck Squamous Cell Carcinoma

Mai, Z., Chen, H., Huang, M., Zhao, X., & Cui, L. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2021.770241 · Cited by 10

The Regulation of Collagen Processing by miRNAs in Disease and Possible Implications for Bone Turnover

Lehmann, T. P., Guderska, U., Kałek, K., Marzec, M., Urbanek, A. N., Czernikiewicz, A., Sasiadek, M. M., Karpiński, P., Pławski, A., Głowacki, M., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010091 · Cited by 10

Reprint of “The complex dynamics of myocardial interstitial fibrosis in heart failure. Focus on collagen cross-linking”

González, A., López, B., Ravassa, S., José, G. S., & Dı́ez, J. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2019.07.016 · Cited by 9

Integrative analysis regarding the correlation between collagen-related genes and prostate cancer

Xiao, Y., Lai, C., Hu, J., Mulati, Y., Xu, X., Luo, J., Kong, D., Liu, C., & Xu, K. (2024) · BMC Cancer · doi:10.1186/s12885-024-12783-9 · Cited by 9

Interactions in hepatic tumor microenvironment: Potential targets and modulations for effective therapy

Altalbawy, F. M. A., Zwamel, A. H., Sanghvi, G. V., Roopashree, R., Kumari, M., Kashyap, A., S, G. S., & Panigrahi, R. (2025) · Pathology - Research and Practice · doi:10.1016/j.prp.2025.156074 · Cited by 9

Identification of a 3-Gene Model as Prognostic Biomarker in Patients With Gastric Cancer

Xue, S., Zheng, T., Yan, J., Ma, J., Lin, C., Dong, S., Chen, W., Li, T., Zhang, X., & Li, G. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.930586 · Cited by 9

Smurf2 Regulates Inflammation and Collagen Processing in Cutaneous Wound Healing through Transforming Growth Factor-β/Smad3 Signaling

Stuelten, C. H., Mélis, N., Subramanian, B. C., Tang, Y., Kimicata, M., Fisher, J. P., Weigert, R., & Zhang, Y. E. (2022) · American Journal Of Pathology · doi:10.1016/j.ajpath.2022.08.002 · Cited by 8

Chromatin run-on sequencing analysis finds that ECM remodeling plays an important role in canine hemangiosarcoma pathogenesis

Mukai, C., Choi, E., Sams, K. L., Klampen, E. Z., Anguish, L. J., Marks, B. A., Rice, E. J., Wang, Z., Choate, L. A., Chou, S., et al. (2020) · BMC Veterinary Research · doi:10.1186/s12917-020-02395-3 · Cited by 11

Procollagen‑lysine, 2‑oxoglutarate 5‑dioxygenase 1 increases cellular proliferation and colony formation capacity in lung cancer via activation of E2F transcription factor 1

Li, B., Yang, H., Shen, B., Huang, J., & Qin, Z. (2021) · Oncology Letters · doi:10.3892/ol.2021.13112 · Cited by 9

Sensory neuropeptide CGRP and its co-receptor RAMP1 drive tumour cell growth in gastrointestinal cancers

Parathan, P., Tran, K., Neil, L., Tan, T., Carli, A. L. E., Liao, Y., Mouradov, D., Duarte, J. D. G., Huber, A., Pal, B., et al. (2025) · BMJ Oncology · doi:10.1136/bmjonc-2025-000842 · Cited by 8

Collagen synthesis and gap junctions: the highway for metastasis of ovarian cancer

Lyu, Y., & Feng, C. (2021) · Laboratory Investigation · doi:10.1038/s41374-021-00546-0 · Cited by 8

Neutrophil Adhesion and the Release of the Free Amino Acid Hydroxylysine

Galkina, S. I., Fedorova, N. V., Ksenofontov, A. L., Serebryakova, M. V., Golenkina, E. A., Stadnichuk, V. I., Baratova, L. A., & Sud’ina, G. F. (2021) · Cells · doi:10.3390/cells10030563 · Cited by 8

Apelin/APJ: Another Player in the Cancer Biology Network

Naldi, L., Peri, A., & Fibbi, B. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26072986 · Cited by 8

A constitutional isomer selective chemical proteomic strategy for system-wide profiling of protein lysine 5-hydroxylation

Sin, Y.-C., Park, M., Griffin, T. J., Yong, J., & Chen, Y. (2024) · Chemical Science · doi:10.1039/d4sc05397d · Cited by 7

PLODs: Novel prognostic biomarkers and potential immunotherapy targets for head and neck squamous cell carcinoma

Gong, S., Wu, C., Duan, Y., Fu, J., Wang, Y., Wu, H., Zhang, B., Tang, J., & Wu, P. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e13479 · Cited by 7

Glycolysis related gene expression signature in predicting prognosis of laryngeal squamous cell carcinoma

Lau, H., Shen, Y., Huang, Q., Huang, H., & Zhou, L. F. (2021) · Bioengineered · doi:10.1080/21655979.2021.1980177 · Cited by 7

PLOD Family: A Novel Biomarker for Prognosis and Personalized Treatment in Soft Tissue Sarcoma

Gong, S., Schopow, N., Duan, Y., Wu, C., Kallendrusch, S., & Osterhoff, G. (2022) · Genes · doi:10.3390/genes13050787 · Cited by 7

Upregulation of GLT25D1 in Hepatic Stellate Cells Promotes Liver Fibrosis via the TGF-β1/SMAD3 Pathway In Vivo and In vitro

Wang, S., He, L., Xiao, F., Gao, M., Wei, H., Yang, J., Shu, Y., Zhang, F., Ye, X., Li, P., et al. (2022) · Journal of Clinical and Translational Hepatology · doi:10.14218/jcth.2022.00005 · Cited by 7

Extracellular matrix protein composition dynamically changes during murine forelimb developmentPreprint

Jacobson, K. R., Saleh, A. M., Lipp, S. N., Ocken, A. R., Kinzer‐Ursem, T. L., & Calve, S. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.06.17.158204 · Cited by 7

MicroRNA-1303 in cancer pathogenesis and therapy: clinical implications for biomarker development and targeted treatment strategies

Zheng, L., Hu, L., & Badehnoosh, B. (2025) · Cancer Cell International · doi:10.1186/s12935-025-03895-8 · Cited by 6

Antigen-presenting CAFs orchestrate immunosuppressive niches via CXCL13-mediated immune cell infiltration dysregulation and prognostic stratification in triple-negative breast cancer

Tian, J., Ye, L., Wang, Z., Zhong, Y., Yao, Y., & Sun, C. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115193 · Cited by 7

Transcriptome-Wide Gene Expression Profiles from FFPE Materials Based on a Nuclease Protection Assay Reveals Significantly Different Patterns between Synovial Sarcomas and Morphologic Mimickers

Borchert, S., Herold, T., Kalbourtzis, S., Hamacher, R., Krause, Y., Berger, S., Guder, W. K., Streitbuerger, A., Hardes, J., Goetz, M., et al. (2022) · Cancers · doi:10.3390/cancers14194737 · Cited by 6

Comprehensive Analysis of the Expression of Cell Adhesion Molecules Genes in Hepatocellular Carcinoma and their Prognosis, and Biological Significance

Wang, J., Hu, Y., Zhao, K., Fan, J., Zhu, J., Li, Q., Chen, Q., & Lu, Y.-Y. (2024) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2902076 · Cited by 7

A bovine model of hypoxia-induced pulmonary hypertension reveals a gradient of immune and matrisome response with a complement signature found in circulation

Williams, J. S., Iheagwam, F. N., Maroney, S. P., Schmitt, L. R., Brown, R. D., Krafsur, G. M., Frid, M. G., McCabe, M. C., Gandjeva, A., Williams, K. J., et al. (2024) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00274.2024 · Cited by 7

Primary angle closure glaucoma is characterized by altered extracellular matrix homeostasis in the iris

Semba, R. D., Zhang, P., Dufresne, C. P., Gao, T., Aljadaan, I., Craven, E. R., Qian, J. X., Edward, D. P., & Mahale, A. M. (2021) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.202000094 · Cited by 6

Modeling Reduced Contractility and Stiffness Using iPSC-Derived Cardiomyocytes Generated From Female Becker Muscular Dystrophy Carrier

Kameda, S., Higo, S., Shiba, M., Kondo, T., Li, J., Liu, L., Tabata, T., Inoue, H., Okuno, S., Ogawa, S., et al. (2023) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2022.11.007 · Cited by 6

EBNA1

Frappier, L. (2025) · Current topics in microbiology and immunology · doi:10.1007/82_2025_299 · Cited by 5

B3GALT6 mutations lead to compromised connective tissue biomechanics in Ehlers-Danlos syndrome

Diana, R., Jolivet, B., Vincourt, J., Hergalant, S., Francius, G., Karami, Y., Khakzad, H., Wild, R., Bourgeais, M., Robert, A., et al. (2025) · JCI Insight · doi:10.1172/jci.insight.179474 · Cited by 6

Pan-Cancer Analysis Reveals the Potential of PLOD1 as a Prognostic and Immune Biomarker for Human Cancer

Zhai, Z., Wang, S., Cao, Y., Liu, J., Zhao, Q., Ji, Y., Yang, X. Q., Tang, X., Ma, J., & Du, P. (2024) · Biomedicines · doi:10.3390/biomedicines12122653 · Cited by 4

Collagen IV assembly is influenced by fluid flow in kidney cell-derived matrices

Tian, P., Koudis, N.-M., Morais, M., Pickard, A., Fresquet, M., Adamson, A. D., Derby, B., & Lennon, R. (2024) · Cells and Development · doi:10.1016/j.cdev.2024.203923 · Cited by 5

Expression and Prognostic Role of PLOD1 in Malignant Glioma

Wang, H., Luo, W., & Dai, L. (2020) · OncoTargets and Therapy · doi:10.2147/ott.s265866 · Cited by 5

Lysyl hydroxylase 2 glucosylates collagen VI to drive lung cancer progression

Wang, S., Guo, H., Fukushima, R., Terajima, M., Liu, M., Xiao, G.-Y., Koudelková, L., Wu, C., Liu, X., Jiang, Y. L., et al. (2025) · Journal of Clinical Investigation · doi:10.1172/jci189197 · Cited by 4

Gluconic acid alleviates hypertrophic scar formation through binding PLOD1, reducing p-AKT signaling and activating autophagy

Li, J., Zeng, S., Sun, Y., Zou, J., Zhang, E., Yan, Q., Chen, L., & Li, J. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.156825 · Cited by 4

RBM15 increase tumor-infiltrating CD4+ T cell in ESCC via modulating of PLOD3

Lin, X. (2024) · American Journal of Cancer Research · doi:10.62347/idcp2061 · Cited by 4

Hypoxia‐induced translation of collagen‐modifying enzymes PLOD2 and P4HA1 is dependent on RBM4 and eIF4E2 in human colon cancer HCT116 cells

Li, H., Hung, H., Yu, J., Liao, Y., & Lai, M. (2024) · FEBS Journal · doi:10.1111/febs.17371 · Cited by 7

3’UTR-Seq analysis of chicken abdominal adipose tissue reveals widespread intron retention in 3’UTR and provides insight into molecular basis of feed efficiency

Wang, Z., Özçam, M., & Abasht, B. (2022) · PLoS ONE · doi:10.1371/journal.pone.0269534 · Cited by 5

A multi-omics study to characterize the transdifferentiation of human dermal fibroblasts to osteoblast-like cells

Pihlström, S., Määttä, K. M., Öhman, T., Mäkitie, R. E., Aronen, M., Varjosalo, M. T., Mäkitie, O., & Pekkinen, M. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.1032026 · Cited by 5

Proteomic analysis uncovers clusterin-mediated disruption of actin-based contractile machinery in the trabecular meshwork to lower intraocular pressurePreprint

Soundararajan, A., Wang, T., & Pattabiraman, P. P. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.02.16.580757 · Cited by 4

Cost-effective Mueller matrix microscopy for label-free differentiation of melanoma from normal skin and common skin cancer types

Le, V. N. D., & Bolden, A. (2025) · Biomedical Optics Express · doi:10.1364/boe.578498 · Cited by 4

Mapping cell type-resolved transcriptomic profiles to patient survival in pancreatic cancer

Tang, R., Jin, L., Chen, C., Liao, Y., Li, D., Li, Y., Chen, Y., Liu, Y., Du, Q., Rong, Z., et al. (2026) · Cancer Cell · doi:10.1016/j.ccell.2026.05.012 · Cited by 3

Genetic Analysis and Functional Study of a Pedigree With Bruck Syndrome Caused by PLOD2 Variant

Wang, R.-L., Ruan, D., Hu, Y., Gan, Y., Lin, X.-F., Fang, Z.-T., Liao, L., Tang, F., He, W., & Luo, J.-W. (2022) · Frontiers in Pediatrics · doi:10.3389/fped.2022.878172 · Cited by 3

Competitive endogenous RNA-mediated upregulation of PLOD2 expression correlates with poor prognosis and tumor immune infiltration of head and neck squamous cell carcinoma

Cai, X., Wang, X., & Cui, L. (2023) · Oral Oncology Reports · doi:10.1016/j.oor.2023.100026 · Cited by 3

Differential effects of angiotensin II and aldosterone on human neutrophil adhesion and concomitant secretion of proteins, free amino acids and reactive oxygen and nitrogen species

Galkina, S. I., Fedorova, N. V., Golenkina, E. A., Ksenofontov, A. L., Serebryakova, M. V., Kordyukova, L. V., Stadnichuk, V. I., Baratova, L. A., & Sud’ina, G. F. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112687 · Cited by 3

Procollagen-lysine 2-oxoglutarate 5-dioxygenases are responsible for 5R-hydroxylysine modification of therapeutic T-cell bispecific monoclonal antibodies produced by Chinese hamster ovary cells

Bauer, N., Boettger, M., Papadaki, S., Leitner, T., Klostermann, S., Kettenberger, H., Georges, G. J., Larraillet, V., von Krüchten, D. G., Hillringhaus, L., et al. (2024) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2024.1414408 · Cited by 3

2-Oxoglutarate-dependent dioxygenases as oxygen sensors: their importance in health and disease

Lee, P. W. T., Kobayashi, M., Dohkai, T., Takahashi, I., Yoshida, T., & Harada, H. (2024) · The Journal of Biochemistry · doi:10.1093/jb/mvae087 · Cited by 4

Genetic Comparison and Selection of Reproductive and Growth-Related Traits in Qinchuan Cattle and Two Belgian Cattle Breeds

Li, X., Niu, P., Wang, X., Huang, F., Wang, J., Qu, H., Han, C., & Gao, Q. (2025) · Animals · doi:10.3390/ani15040608 · Cited by 3

CKAP4 and PLOD2 as novel prognostic biomarkers in hepatocellular carcinoma: a proteomics-driven risk stratification model

Lu, Q., Cao, Z., Xiong, Y., Huang, J., Zeng, H., Chen, Z., Shu, Y., Tan, Y., Long, X., Liu, X., et al. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1577161 · Cited by 3

Collagen synthesis in the skin: genetic and epigenetic aspects

Потекаев, Н. Н., Borzykh, O. B., Shnayder, N. A., Петрова, М. М., Karpova, E. I., & Nasyrova, R. F. (2022) · Bulletin of Siberian Medicine · doi:10.20538/1682-0363-2022-3-217-226 · Cited by 4

Full‐Length Human Collagen Lysyl Hydroxylases

Scietti, L., & Forneris, F. (2020) · Encyclopedia of Inorganic and Bioinorganic Chemistry · doi:10.1002/9781119951438.eibc2739 · Cited by 3

Glycosite Mapping and in situ Mass Spectrometry Imaging of MUC2 Glycopeptides via On-slide Digestion with Mucinase StcEPreprint

Lowery, S., Tran, I. P., Grimsley, G., Stubler, R., Mahoney, K. E., Lucas, T. M., Charkoftaki, G., Santos‐Neto, Á. J., Varki, N. M., Vasiliou, V., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.16.613285 · Cited by 3

Integrative machine learning and transcriptomic analysis identifies key molecular targets in MNPN-associated oral squamous cell carcinoma pathogenesis

Wang, X., Jin, P., Xu, J., Li, J., & Ji, M. (2025) · Frontiers in Bioinformatics · doi:10.3389/fbinf.2025.1664576 · Cited by 2

Integrated Analysis of Proteomics and Metabolomics for Heat Stress in Chinese Holstein Cows

Wang, X. Q., Yuan, Y., Pei, F., Yang, J., Wang, C., Bao, P., Zhao, X., Liu, H., Gao, H., Hou, M., et al. (2025) · Animals · doi:10.3390/ani15203049 · Cited by 2

PLOD1 promotes gastric cancer metastasis and immune escape by mediating extracellular matrix remodeling

Chen, Y., & Wu, X. (2025) · Discover Oncology · doi:10.1007/s12672-025-03774-8 · Cited by 2

Cancer-Associated Fibroblast-Centric Risk Model Predicts Immunotherapy Resistance in Pancreatic Cancer and Reveals PLOD2 as a Key Stromal Therapeutic Target

Cao, P., Cao, F., Shui, Z. N., Zhang, X., Lv, M., Xu, H., Ran, J., Ding, W., Zhou, E., Zhang, D., et al. (2025) · Frontiers in Bioscience-Landmark · doi:10.31083/fbl46316 · Cited by 2

Characterization of Usher Syndrome Type 2-Associated Proteins in the Retina via Affinity Purification-Mass Spectrometry

Zou, J., Yu, D., Mathur, P. D., Nordhagen, C. P., Zou, X., Bonaldo, P., & Yang, J. (2026) · Molecular & Cellular Proteomics · doi:10.1016/j.mcpro.2026.101526 · Cited by 2

Colorectal cancer stem cells: overview and potential targeted therapy

Amălinei, C., Pricope, D. L., & Grigoraş, A. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-13212-4.00018-0 · Cited by 2

Recent Advances and Therapeutic Implications of 2-Oxoglutarate-Dependent Dioxygenases in Ischemic Stroke

Xie, J. M., & Zhang, Z. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03790-1 · Cited by 3

The collagen-modifying enzyme GLT25D1 is a prognostic indicator related to immunosuppression and malignant phenotypes in hepatocellular carcinoma

Qiu, S., Han, H., Zhang, H., Yang, M., Wang, H., Li, K., Li, L., & Yang, G. (2025) · Cancer Cell International · doi:10.1186/s12935-025-03715-z · Cited by 2

Mass spectrometry reveals age‐dependent collagen decline in murine atria

Ringström, N., Edling, C. E., Nalesso, G., Barallobre‐Barreiro, J., & Jeevaratnam, K. (2025) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.15341 · Cited by 2

Super-enhanced MARCO variant drives triple-negative breast cancer progression

Lin, W.-C., & Lin, F. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2217953119 · Cited by 2

Single Nucleus RNA Sequencing of Remnant Kidney Biopsies and Urine Cell RNA Sequencing Reveal Cell Specific Markers of Covid-19 Acute Kidney InjuryPreprint

Ghag, R. R., Kaushal, M., Nwanne, G., Knoten, A. L., Kiryluk, K., Rosenberg, A. Z., Menez, S. P., Bagnasco, S. M., Sperati, C. J., Atta, M. G., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.10.566497 · Cited by 3

Aberrant expression of COL4A1 in age-related cataract and its effect on cell proliferation, apoptosis and gene expression changes

Zhu, D., Wang, L., He, Y., & Zhang, H.-Z. (2023) · International Journal of Ophthalmology · doi:10.18240/ijo.2023.03.01 · Cited by 1

Investigating the Impact of Ocean Acidification on Anti-Stress Mechanisms in Sepia esculenta Larvae Based on Transcriptome Profiling

Wang, Y., Liu, X., Lv, T., Wang, W., Sun, G., Yang, J., & Li, Z. (2024) · Journal of Ocean University of China · doi:10.1007/s11802-024-5772-0 · Cited by 1

Genetic Insights into the Enigma of Family Intracranial Aneurysms

Abulizi, A., Su, R., Wu, P., Cheng, X., Maimaitili, A., & Wang, Z. (2024) · World Neurosurgery · doi:10.1016/j.wneu.2024.10.090 · Cited by 1

Discovery of Glucose Metabolism-Associated Genes in Neuropathic Pain: Insights from Bioinformatics

Yu, Y., Cheung, Y.-T., & Cheung, C.-W. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252413503 · Cited by 1

Senescence caused by telomerase inactivation in myeloid, mesenchymal, and endothelial cells has distinct effects on cancer progression

Rupert, J. E., Gao, Z., Yu, Y., & Kolonin, M. G. (2025) · Aging · doi:10.18632/aging.206268 · Cited by 1

Global matrisome changes in obese lung are linked to fibroblastic stroma and premature aging

Rottmann, S., Li, J. J., Zurkovic, J., Bravo, P. S., Lindner, A. U., Qin, J., Kallabis, S., Mei, Q., Liu, X., Thiele, C., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116285 · Cited by 1

Prognostic biomarker and clinical significance of PLOD gene family in clear cell renal cell carcinoma

Shang, X., Liu, L., Yang, Z., Yan, M., Ren, R., Guo, K., Wang, J., Zhang, W., Chang, J.-S., Li, J., et al. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1613540 · Cited by 1

CD8+ T cells drive myofibroblast activation and contraction via JAK/STAT3 and TGFβ signaling

Papadimitriou, T. I., Essen, A., Willemse, M., Dorst, D. N., Vitters, E. L., Walgreen, B., Koenen, H. J. P. M., van der Kraan, P. M., Koenders, M. I., Thurlings, R. M., et al. (2025) · iScience · doi:10.1016/j.isci.2025.113904 · Cited by 1

Review: Cell and Molecular Biology of Healing in Amputated Limbs of the Lizard Podarcis muralis Reveal a Gene Activation Program for Scarring

Alibardi, L. (2025) · Acta Zoologica · doi:10.1111/azo.70018 · Cited by 1

Engineering a multilayered micro-vascularized soft tissue graft: Integrating polyurethane composite nanofibres with co-cultures of human adipose-derived endothelial and stem cells

Webb, B. C. W., Tran, G., Devaraj, K., Lindsay, E., Kuzmanov, U., Gramolini, A. O., Hofer, S. O. P., & Santerre, J. P. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.124064 · Cited by 1

Mass spectrometry-based multi-omics analysis elucidates immune microenvironmental characteristics and the risk of distant metastasis in N1c colorectal cancer

Zhu, B., Zheng, C., Xu, H., Zheng, Y., Liu, Y., Li, P., Jin, H., Ou, B., Chen, Y., Wang, Z., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1590042 · Cited by 1

Metabolic-epigenetic reprogramming via the PLOD1–PFKP axis drives cisplatin resistance in HNSCC

Zhao, X., Liao, X., Lin, Y., Chen, X., Lin, P., Lu, Y., Zheng, J., Zou, M., Guo, B., & Cui, L. (2026) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2026.03.053 · Cited by 1

Exploring mechanisms of scar-free skin wound healing in adult zebrafish in comparison to mouse

Küçükaylak, I., Halwas, K., Martínez-Morcillo, F. J., Reiche, N., Metzger, M., Comelli, P., Voigt, B., Brinckmann, J., Eming, S. A., & Hammerschmidt, M. (2026) · PLoS Genetics · doi:10.1371/journal.pgen.1012200 · Cited by 2

Extending the global landscape of Bruck syndrome: Case series of Indonesian and Ukrainian patients with PLOD2 pathogenic variants and literature review

Paveta, D. A., Utari, A., Cayami, F. K., Maugeri, A., Märtson, A., Kõks, S., Pashenko, A., Khmyzov, S., Eekhoff, E. M. W., Maasalu, K., et al. (2026) · Bone Reports · doi:10.1016/j.bonr.2026.101938 · Cited by 1

Stages of preadipocyte differentiation: biomarkers and pathways for extracellular structural remodeling

Hu, Z., Liu, Y., Yao, Z., Chen, L., Wang, G., Liu, X., Tian, Y., & Cao, G. (2022) · Hereditas · doi:10.1186/s41065-022-00261-w · Cited by 1

Extracellular Matrix as a Metabolic Niche in Cancer

Sebestyén, A. R., Dankó, T., Sztankovics, D., Moldvai, D., Krencz, I., Raffay, R. E., & Petővári, G. (2022) · Biology of extracellular matrix · doi:10.1007/978-3-030-99708-3_13 · Cited by 1

Influence of Anti-Endometrial Antibodies on the Activity of Inflammatory Processes in Patients with Genital Endometriosis

Sevinj, S., & Hicran, B. (2019) · International journal of Gynecology Obstetrics and Neonatal Care · doi:10.15379/2408-9761.2019.06.01.03

Phenotypic evolution of cancer cells: structural requirements for survival

Atrian, F., & Lelièvre, S. A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-08-102983-1.00002-8

Patent Highlights April–May 2020

Mucke, H. A. (2020) · Pharmaceutical Patent Analyst · doi:10.4155/ppa-2020-0018

Peer Review #1 of "The relationship between PLOD1 expression level and glioma prognosis investigated using public databases (v0.1)"

(2021) · PeerJ · doi:10.7287/peerj.11422v0.1/reviews/1

Overexpressing PLOD Family Genes Predict Poor Prognosis In Pancreatic CancerPreprint

Zhang, J., Tian, Y. Z., Mo, S., & Fu, X. (2021) · Research Square · doi:10.21203/rs.3.rs-895700/v1

Label-free Quantitative Proteomics Combined With Transcriptomics Revealed the Importance of Cardiac Development in Producing the High Metabolic Capacity of Yellowfin Tuna (Thunnus Albacares)Preprint

Yan, L. E., Guo, J., Zhao, C., Liu, Y., Wang, P., Fan, S., Qiu, L., & Chen, Z. (2022) · Research Square · doi:10.21203/rs.3.rs-1059714/v1

Peer Review #2 of "The relationship between PLOD1 expression level and glioma prognosis investigated using public databases (v0.1)"

(2021) · PeerJ · doi:10.7287/peerj.11422v0.1/reviews/2

Elucidating endothelial pathology in polypoidal choroidal vasculopathy : a patient-derived cellular model approach

Yeo, N. J. Y. (2022) · DR-NTU (Nanyang Technological University) · doi:10.32657/10356/155373

Regulation of EBNA1 Protein Stability by PLOD1 Lysine HydroxylasePreprint

Dheekollu, J., Wiedmer, A., Soldan, S. S., Castro-Muñoz, L. J., Tang, H., Speicher, D. W., & Lieberman, P. M. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.03.29.486189

Computational analysis and characterization of dysregulated chromatin interactions and RNA biology in acute myeloid leukemia

Kong, L. (2021) · doi:10.32657/10356/155629

Hypoxia and the Metastatic Cascade

Gandhi, S., Khanna, S., Kaushik, S., Chaudhry, D., Ghorawat, P., Chongtham, J., & Srivastava, T. (2023) · Springer eBooks · doi:10.1007/978-981-99-0313-9_9

Characterization of Procollagen-lysine, 2-oxoglutarate 5-dioxygenases as Therapeutic Targets in a Pan-Cancer StudyPreprint

Liu, W., Liu, J., Deng, J., Zhan, T., Han, Z., Tan, J., Liu, M., Chen, M., Xia, T., & Huang, X. (2023) · Research Square · doi:10.21203/rs.3.rs-3199402/v1

PLOD2 in cancer research

Du, H., Pang, M., Hou, X., Yuan, S., & Sun, L. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.04.023 · Cited by 106

The role of PLOD2 in cancer metastasis

Bronts, S. (2019)

PLOD2 regulated by transcription factor FOXA1 promotes metastasis in NSCLC

Du, H., Chen, Y., Hou, X., Huang, Y., Wei, X., Yu, X., Feng, S. L., Wu, Y., Zhan, M., Shi, X., et al. (2017) · Cell Death and Disease · doi:10.1038/cddis.2017.553 · Cited by 97

The PLOD2 promotes tumor progression in colorectal cancer through the PI3K-AKT pathwayPreprint

Chen, D., Zhang, M., Zhou, Y., Zhu, H., Deng, Z., Li, O., & Zhou, Y. (2024) · Research Square · doi:10.21203/rs.3.rs-5266104/v1

Podoplanin: a novel regulator of tumor invasion and metastasis

Dang, Q., Liu, J., Li, J., & Sun, Y. (2014) · Medical Oncology · doi:10.1007/s12032-014-0024-6 · Cited by 42