The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Antimicrobial Peptides: Interaction With Model and Biological Membranes and Synergism With Chemical Antibiotics
Open accessAbstract
Antimicrobial peptides (AMPs) are promising novel antibiotics since they have shown antimicrobial activity against a wide range of bacterial species, including multiresistant bacteria; however, toxicity is the major barrier to convert antimicrobial peptides into active drugs. A profound and proper understanding of the complex interactions between these peptides and biological membranes using biophysical tools and model membranes seems to be a key factor in the race to develop a suitable antimicrobial peptide therapy for clinical use. In the search for such therapy, different combined approaches with conventional antibiotics have been evaluated in recent years and demonstrated to improve the therapeutic potential of AMPs. Some of these approaches have revealed promising additive or synergistic activity between AMPs and chemical antibiotics. This review will give an insight into the possibilities that physicochemical tools can give in the AMPs research and also address the state of the art on the current promising combined therapies between AMPs and conventional antibiotics, which appear to be a plausible future opportunity for AMPs treatment.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Trott, O., & Olson, A. J. (2010) · Journal of Computational Chemistry · doi:10.1002/jcc.21334 · Cited by 38,412
Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?
Brogden, K. A. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1098 · Cited by 5,829
Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America
Boucher, H. W., Talbot, G. H., Bradley, J. S., Edwards, J. E., Gilbert, D., Rice, L. B., Scheld, M., Spellberg, B., & Bartlett, J. (2009) · Clinical Infectious Diseases · doi:10.1086/595011 · Cited by 4,958
Mechanisms of Antimicrobial Peptide Action and Resistance
Yeaman, M. R., & Yount, N. Y. (2003) · Pharmacological Reviews · doi:10.1124/pr.55.1.2 · Cited by 3,001
Synergy, antagonism, and what the chequerboard puts between them
Odds, F. C. (2003) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkg301 · Cited by 2,481
Antibacterial peptides for therapeutic use: obstacles and realistic outlook
MARR, A., GOODERHAM, W., & HANCOCK, R. (2006) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2006.04.006 · Cited by 1,051
The relationship between peptide structure and antibacterial activity
Powers, J.-P. S., & Hancock, R. E. W. (2003) · Peptides · doi:10.1016/j.peptides.2003.08.023 · Cited by 948
Role of Peptide Hydrophobicity in the Mechanism of Action of α-Helical Antimicrobial Peptides
Chen, Y., Guarnieri, M. T., Vasil, A. I., Vasil, M. L., Mant, C. T., & Hodges, R. S. (2007) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00925-06 · Cited by 757
Antimicrobial peptides: linking partition, activity and high membrane-bound concentrations
Melo, M. N., Ferre, R., & Castanho, M. A. R. B. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2095 · Cited by 709
Ligand binding assays at equilibrium: validation and interpretation
Hulme, E. C., & Trevethick, M. A. (2010) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00604.x · Cited by 657
Cited by
Mode-of-Action of Antimicrobial Peptides: Membrane Disruption vs. Intracellular Mechanisms
Benfield, A. H., & Henriques, S. T. (2020) · Frontiers in Medical Technology · doi:10.3389/fmedt.2020.610997 · Cited by 367
Antimicrobial Peptides: An Update on Classifications and Databases
Bin Hafeez, A., Jiang, X., Bergen, P. J., & Zhu, Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222111691 · Cited by 341
Antimicrobial Peptides—Mechanisms of Action, Antimicrobial Effects and Clinical Applications
Talapko, J., Meštrović, T., Juzbašić, M., Tomas, M., Erić, S., Horvat Aleksijević, L., Bekić, S., Schwarz, D., Matić, S., Neuberg, M., et al. (2022) · Antibiotics · doi:10.3390/antibiotics11101417 · Cited by 281
Antimicrobial peptides: Structure, mechanism, and modification
Chen, N., & Jiang, C. (2023) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2023.115377 · Cited by 279
Lima, P. G., Oliveira, J. T. A., Amaral, J. L., Freitas, C. D. T., & Souza, P. F. N. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119647 · Cited by 170
Metadata
- Authors
- Hollmann, A., Martinez, M., Maturana, P., Semorile, L. C., & Maffia, P. C.
- Venue
- Frontiers in Chemistry
- Publisher
- Frontiers Media SA
- Published
- 2018-06-05
- Volume
- 6
- Pages
- 204-204
- ISSN
- 2296-2646 (ISSN-L)
- OpenAlex
- W2804562858
- Cited by
- 334
- References
- 84
- FWCI
- 20.56
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Antimicrobial Peptides: Interaction With Model and Biological Membranes and Synergism With Chemical Antibiotics. https://app.cochat.ai/papers/10.3389/fchem.2018.00204
- The paper
- Hollmann, A., Martinez, M., Maturana, P., Semorile, L. C., & Maffia, P. C. (2018). Antimicrobial Peptides: Interaction With Model and Biological Membranes and Synergism With Chemical Antibiotics. Frontiers in Chemistry. https://doi.org/10.3389/fchem.2018.00204
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
