The DOI matches its Crossref record; 110 of the 110 references it cites were found in a registry or an index.
Arterial Stiffness and Hypertension in the Elderly
Open accessAbstract
Hypertension prevalence increases with age. Age and high blood pressure are the two main determinants of arterial stiffness. In elderly hypertensives, large arteries stiffen and systolic and pulse pressures increase, due to wave reflections. A major reason for measuring arterial stiffness in clinical practice in elderly hypertensive patients comes from the repeated demonstration that arterial stiffness and wave reflections have a predictive value for CV events. A large body of evidence has been published during the last two decades, concerning the epidemiology, pathophysiology, and pharmacology of large arteries in hypertension in various settings of age. Particularly, two expert consensus documents have reviewed the methodological agreements for measuring arterial stiffness. The concepts of Early Vascular Ageing (EVA) and Supernormal Vascular Ageing (SUPERNOVA) help to better understand on which determinants of arterial stiffness it is possible to act, in order to limit target organ damage and cardiovascular complications. This review will address the issues of the cellular and molecular mechanisms of arterial stiffening in elderly hypertensives, the consequences of arterial stiffening on central systolic and pulse (systolic minus diastolic, PP) pressures and target organs, the methodology for measuring arterial stiffness, central pulse pressure and wave reflection, the epidemiological determinants of arterial stiffening in elderly hypertensives, the pharmacology of arterial destiffening, and how the concepts of EVA and SUPERNOVA apply to the detection of organ damage and prevention of CV complications.
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Cites
2018 ESC/ESH Guidelines for the management of arterial hypertension
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Self-citationExpert consensus document on arterial stiffness: methodological issues and clinical applications
Laurent, S., Cockcroft, J., Van Bortel, L., Boutouyrie, P., Giannattasio, C., Hayoz, D., Pannier, B., Vlachopoulos, C., Wilkinson, I., Struijker-Boudier, H., et al. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehl254 · Cited by 6,077
Self-citationPrediction of Cardiovascular Events and All-Cause Mortality With Arterial Stiffness
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Laurent, S., Boutouyrie, P., Asmar, R., Gautier, I., Laloux, B., Guize, L., Ducimetiere, P., & Benetos, A. (2001) · Hypertension · doi:10.1161/01.hyp.37.5.1236 · Cited by 3,856
Self-citationTreatment of hypertension in patients 80 years of age or older
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Self-citationMcDonald's blood flow in arteries; theoretical, experimental and clinical principles
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Hemodynamic Patterns of Age-Related Changes in Blood Pressure: The Framingham Heart Study
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Cited by
Effects of Different Long-Term Exercise Modalities on Tissue Stiffness
Thomas, E., Ficarra, S., Nakamura, M., Paoli, A., Bellafiore, M., Palma, A., & Bianco, A. (2022) · Sports Medicine - Open · doi:10.1186/s40798-022-00462-7 · Cited by 24
Zare, M. G., Okati-Aliabad, H., Ansari-Moghaddam, A., Mohammadi, M., & Shahraki-Sanavi, F. (2023) · PLOS ONE · doi:10.1371/journal.pone.0295270 · Cited by 11
Jafarikhah, R., Damirchi, A., Rahmani Nia, F., Razavi-Toosi, S. M. T., Shafaghi, A., & Asadian, M. (2023) · Scientific Reports · doi:10.1038/s41598-023-42687-w · Cited by 7
Metadata
- Authors
- Laurent, S., & Boutouyrie, P.
- Venue
- Frontiers in Cardiovascular Medicine
- Publisher
- Frontiers Media SA
- Published
- 2020-10-29
- Volume
- 7
- Pages
- 544302-544302
- ISSN
- 2297-055X (ISSN-L)
- OpenAlex
- W3097573154
- Cited by
- 266
- References
- 110
- FWCI
- 15.08
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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