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Prognostic Value of Complement Properdin in Cancer

Mangogna, A., Varghese, P. M., Agostinis, C., Alrokayan, S., Khan, H. A., Stover, C. M., Belmonte, B., Martorana, A., Ricci, G., Bulla, R., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.614980 · Cited by 26 · see citing works

Serum properdin consumption as a biomarker of C5 convertase dysregulation in C3 glomerulopathy

Corvillo, F., García‐Morato, M. B., Nozal, P., Garrido, S., Tortajada, A., de Córdoba, S. R., & López‐Trascasa, M. (2015) · Clinical & Experimental Immunology · doi:10.1111/cei.12754 · Cited by 26 · see citing works

Human Properdin Modulates Macrophage: Mycobacterium bovis BCG Interaction via Thrombospondin Repeats 4 and 5

Al-Mozaini, M., Tsolaki, A. G., Abdul-Aziz, M., Abozaid, S. M., Al‐Ahdal, M. N., Pathan, A. A., Murugaiah, V., Makarov, E. M., Kaur, A., Sim, R. B., et al. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00533 · Cited by 23 · see citing works

On the Functional Overlap between Complement and Anti-Microbial Peptides

Zimmer, J., Hobkirk, J., Mohamed, F., Browning, M. J., & Stover, C. M. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00689 · Cited by 22 · see citing works

Avacopan for the treatment of ANCA-associated vasculitis

Osman, M., Tervaert, J. W. C., & Pagnoux, C. (2021) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2021.1932466 · Cited by 21 · see citing works

Complement-targeted therapies in kidney transplantation—insights from preclinical studies

Anwar, I. J., DeLaura, I. F., Ladowski, J. M., Gao, Q., Knechtle, S. J., & Kwun, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.984090 · Cited by 21 · see citing works

Monomeric C-reactive protein inhibits renal cell-directed complement activation mediated by properdin

O'Flynn, J., van der Pol, P., Dixon, K. O., Prohászka, Z., Daha, M. R., & van Kooten, C. (2016) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00645.2014 · Cited by 21 · see citing works

Interactions of the innate immune system with carbon nanotubes

Pondman, K. M., Salvador-Morales, C., Paudyal, B., Sim, R. B., & Kishore, U. (2017) · Nanoscale Horizons · doi:10.1039/c6nh00227g · Cited by 21 · see citing works

A recombinant two-module form of human properdin is an inhibitor of the complement alternative pathway

Kouser, L., Abdul-Aziz, M., Tsolaki, A. G., Singhal, D., Schwaeble, W., Urban, B. C., Khan, H. A., Sim, R. B., & Kishore, U. (2016) · Molecular Immunology · doi:10.1016/j.molimm.2016.03.005 · Cited by 18 · see citing works

Complement-Independent Modulation of Influenza A Virus Infection by Factor H

Murugaiah, V., Varghese, P. M., Saleh, S. M., Tsolaki, A. G., Alrokayan, S., Khan, H. A., Collison, K. S., Sim, R. B., Nal, B., Al-Mohanna, F. A., et al. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00355 · Cited by 16 · see citing works

Autoantibody Profiling in Plasma of Dengue Virus–Infected Individuals

Vo, H. T. M., Duong, V., Ly, S., Li, Q., Dussart, P., & Cantaert, T. (2020) · Pathogens · doi:10.3390/pathogens9121060 · Cited by 16 · see citing works

Low molecular weight polysialic acid binds to properdin and reduces the activity of the alternative complement pathway

Shahraz, A., Lin, Y.-C., Mbroh, J., Winkler, J., Liao, H., Lackmann, M., Bungartz, A., Zipfel, P. F., Skerka, C., & Neumann, H. (2022) · Scientific Reports · doi:10.1038/s41598-022-09407-2 · Cited by 15 · see citing works

Enumerating the role of properdin in the pathogenesis of IgA nephropathy and its possible therapies

Ghosh, S., Das, S., Mukherjee, J., Abdullah, S., Mondal, R., Sultana, S., Sehgal, A., & Behl, T. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.107429 · Cited by 15 · see citing works

Mathematical Modelling of Alternative Pathway of Complement System

Bakshi, S., Cunningham, F., Nichols, E.-M., Biedzka-Sarek, M., Neisen, J., Petit-Frere, S., Bessant, C. M., Bansal, L., Peletier, L. A., Zamuner, S., et al. (2020) · Bulletin of Mathematical Biology · doi:10.1007/s11538-020-00708-z · Cited by 13 · see citing works

Association of elevated levels of peripheral complement components with cortical thinning and impaired logical memory in drug-naïve patients with first-episode schizophrenia

Yu, H., Ni, P., Tian, Y., Zhao, L., Li, M., Li, X., Wei, W., Wei, J., Wang, Q., Guo, W., et al. (2023) · Schizophrenia · doi:10.1038/s41537-023-00409-1 · Cited by 12 · see citing works

Longitudinal Stroke Recovery Associated With Dysregulation of Complement System—A Proteomics Pathway Analysis

Nguyen, V., Riddell, N., Crewther, S. G., Faou, P., Rajapaksha, H., Howells, D. W., Hankey, G. J., Wijeratne, T., Ma, H., Davis, S. M., et al. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.00692 · Cited by 11 · see citing works

Role of auto-antibodies in the mechanisms of dengue pathogenesis and its progression: a comprehensive review

Ghorai, T., Sarkar, A., Roy, A., Bhowmick, B., Nayak, D., & Das, S. (2024) · Archives of Microbiology · doi:10.1007/s00203-024-03954-0 · Cited by 11 · see citing works

An integrative pan-cancer analysis of MASP1 and the potential clinical implications for the tumor immune microenvironment

Yu, H., Wang, C., Ke, S., Xu, Y., Lu, S., Feng, Z., Bai, M., Qian, B., Xu, Y., Li, Z., et al. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.135834 · Cited by 10 · see citing works

Protective role of complement factor H against the development of preeclampsia

Yasmin, H., Agostinis, C., Toffoli, M., Roy, T., Pegoraro, S., Balduit, A., Zito, G., Simone, N. D., Ricci, G., Madan, T., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1351898 · Cited by 10 · see citing works

Complement and Fungal Dysbiosis as Prognostic Markers and Potential Targets in PDAC Treatment

Speth, C., Bellotti, R., Schäfer, G., Rambach, G., Texler, B., Thurner, G. C., Öfner, D., Lass‐Flörl, C., & Maglione, M. (2022) · Current Oncology · doi:10.3390/curroncol29120773 · Cited by 9 · see citing works

Innate Immune Pattern Recognition Receptors of Mycobacterium tuberculosis: Nature and Consequences for Pathogenesis of Tuberculosis

Tsolaki, A. G., Varghese, P. M., & Kishore, U. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-67452-6_9 · Cited by 9 · see citing works

Avacopan for the treatment of ANCA-associated vasculitis: an update

Osman, M. S., Tervaert, J. W. C., & Pagnoux, C. (2022) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2023.2162041 · Cited by 8 · see citing works

Combining MAP‐1:CD35 or MAP‐1:CD55 fusion proteins with pattern‐recognition molecules as novel targeted modulators of the complement cascade

Pérez‐Alós, L., Bayarri‐Olmos, R., Skjoedt, M., & Garred, P. (2019) · The FASEB Journal · doi:10.1096/fj.201901643r · Cited by 8 · see citing works

Widely used commercial ELISA does not detect preHP-2, but recognizes properdin as a potential second member of the zonulin familyPreprint

Massier, L., Crane, A., Heyne, H., Tönjes, A., Schleinitz, D., Ihling, C. H., Stümvoll, M., Freire, R., Fiorentino, M., Fasano, A., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/157578 · Cited by 8 · see citing works

Apoptosis in post-streptococcal glomerulonephritis and mechanisms for failed of inflammation resolution

Mosquera-Sulbarán, J., Pedreáñez, A. B., Vargas, R., & Hernández-Fonseca, J. P. (2023) · Pediatric Nephrology · doi:10.1007/s00467-023-06162-y · Cited by 7 · see citing works

Sialylation as a checkpoint for inflammatory and complement-related retinal diseases

Min, Y., Cuevas-Ríos, G., Langmann, T., & Neumann, H. (2025) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2025.1623755 · Cited by 6 · see citing works

Circulating complement factor H levels are associated with disease severity and relapse in autoimmune hepatitis

Hayashi, M., Abe, K., Fujita, M., Takahashi, A., Sekine, H., & Ohira, H. (2022) · JHEP Reports · doi:10.1016/j.jhepr.2022.100497 · Cited by 6 · see citing works

Human coagulation factor X and CD5 antigen-like are potential new members of the zonulin family proteins

Konno, T., Martinez, E. E., Ji, J., Miranda-Ribera, A., Fiorentino, M. R., & Fasano, A. (2022) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2022.11.047 · Cited by 6 · see citing works

Complement profile in microscopic polyangiitis and granulomatosis with polyangiitis: analysis using sera from a nationwide prospective cohort study

Fukui, S., Ichinose, K., Sada, K., Miyamoto, J., Harigai, M., Amano, K., Atsumi, T., Takasaki, Y., Dobashi, H., Arimura, Y., et al. (2020) · Scandinavian Journal of Rheumatology · doi:10.1080/03009742.2019.1695927 · Cited by 6 · see citing works

The Endothelial Glycocalyx: The First Line of Defense in the Prevention and Treatment of Kidney Diseases

Yuan, X., Jia, M., Zhou, L., Hou, G., Zhang, B., Ouyang, X., & Huang, Y. (2025) · Kidney Medicine · doi:10.1016/j.xkme.2025.101122 · Cited by 5 · see citing works

Absence of complement factor H reduces physical performance in C57BL6 mice

Seldeen, K. L., Thiyagarajan, R., Redae, Y. Z., Jacob, A., Troen, B. R., Quigg, R. J., & Alexander, J. J. (2020) · Immunobiology · doi:10.1016/j.imbio.2020.152003 · Cited by 5 · see citing works

Development and characterization of mouse monoclonal antibodies to eight human complement components: Analysis of reactivity with orthologs of nine mammalian genera

Monedero, M., Infantes‐Lorenzo, J. A., Moreno, I., Algíbez, A. M., Macı́as, R. I. R., Toraño, A., & Domínguez, M. (2018) · Comparative Immunology Microbiology and Infectious Diseases · doi:10.1016/j.cimid.2018.11.008 · Cited by 5 · see citing works

Temporal patterns of gene expression in response to inoculation with a virulent Anaplasma phagocytophilum strain in sheep

Eskeland, S., Granquist, E. G., Stuen, S., Lybeck, K. R., Wilhelmsson, P., Lindgren, P., & Makvandi‐Nejad, S. (2023) · Scientific Reports · doi:10.1038/s41598-023-47801-6 · Cited by 4 · see citing works

Complement protein C1q binds soluble antigens of Leishmania major (SLA) via the globular head region, activates the classical pathway, and modulates macrophage immune response

Al-Qahtani, A. A., Al‐Ahdal, M. N., & Alkahtani, S. H. (2021) · Journal of King Saud University - Science · doi:10.1016/j.jksus.2021.101365 · Cited by 4 · see citing works

Liver factor B silencing to cure C3 glomerulopathy: Evidence from a mouse model of complement dysregulation

Zanchi, C., Locatelli, M., Corna, D., Cerullo, D., Fishilevich, E., Desai, D., Rottoli, D., Donadelli, R., Noris, M., Zoja, C., et al. (2023) · Molecular Immunology · doi:10.1016/j.molimm.2023.07.010 · Cited by 4 · see citing works

Biomarkers in the Management of Complement-Mediated Kidney Diseases in the Era of Complement Therapeutics

Rizk, D. V., Dixon, B. P., Chan, M., Cook, H. T., Frazer‐Abel, A. A., & Tang, S. C. W. (2025) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.0000000967 · Cited by 3 · see citing works

Inhibition of the Alternative Complement Pathway May Cause Secretion of Factor B, Enabling an Early Detection of Pancreatic Cancer

Lee, M. J., Cho, J.-Y., Bae, S., Jung, H. S., Kang, C. M., Kim, S. H., Choi, H. J., Lee, C., Kim, H., Jo, D., et al. (2024) · Journal of Proteome Research · doi:10.1021/acs.jproteome.3c00695 · Cited by 3 · see citing works

Modeling C3 glomerulopathies: C3 convertase regulation on an extracellular matrix surface

Pisarenka, S., Meyer, N. C., Xiao, X., Goodfellow, R. X., Nester, C., Zhang, Y., & Smith, R. J. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1073802 · Cited by 3 · see citing works

The Role of Properdin in Killing of Non-Pathogenic Leptospira biflexa

Martinez, A. P. G., Abreu, P. A. E., Vasconcellos, S. D. A., Ho, P. L., Ferreira, V. P., Saggu, G., Barbosa, A. S., & Isaac, L. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.572562 · Cited by 3 · see citing works

Human complement Factor H and Properdin act as soluble pattern recognition receptors and differentially modulate SARS-CoV-2 InfectionPreprint

Beirag, N., Varghese, P. M., Kumar, C., Idicula‐Thomas, S., Neto, M. M., Khan, H. A., Sim, R. B., Madan, T., Temperton, N. J., & Kishore, U. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.07.07.548083 · Cited by 3 · see citing works

Differential modulation of SARS-CoV-2 infection by complement factor H and properdin

Kishore, U., Varghese, P. M., Kumar, C., Idicula‐Thomas, S., Neto, M. M., Tsolaki, A. G., Ponnachan, P., Masmoudi, K., al-Ramadi, B. K., Vatish, M., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1620229 · Cited by 2 · see citing works

The role of gamma globulin, complement component 1q, factor B, properdin, body temperature, C-reactive protein and serum amyloid alpha to the activity and the function of the human complement system and its pathways

Atosuo, J., Karhuvaara, O., Suominen, E. N., Virtanen, J., Vilén, L., & Nuutila, J. (2024) · Journal of Immunological Methods · doi:10.1016/j.jim.2024.113709 · Cited by 2 · see citing works

Kaposi’s Sarcoma-Associated Herpesvirus and Host Interaction by the Complement System

Yoo, S., & Lee, M. (2020) · Pathogens · doi:10.3390/pathogens9040260 · Cited by 2 · see citing works

Angiotensin II and post-streptococcal glomerulonephritis

Mosquera-Sulbarán, J., Pedreáñez, A. B., Carrero, Y. N., & Hernández-Fonseca, J. P. (2024) · Clinical and Experimental Nephrology · doi:10.1007/s10157-023-02446-7 · Cited by 1 · see citing works

Interactions Between the Innate and Adaptive Immune Responses

George, A. J. T., Aiyan, A. A., al-Ramadi, B. K., & Kishore, U. (2025) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-85340-1_12 · Cited by 1 · see citing works

Discovery and characterization of vertebrate sialoglycan-binding proteins

Adler, L., Yehuda, S., Varki, A. P., & Padler‐Karavani, V. (2025) · Seminars in Immunology · doi:10.1016/j.smim.2025.101978 · Cited by 1 · see citing works

Differential expression of complement Properdin and Factor H in the placentae and umbilical cords of mothers with Preeclampsia, Gestational Diabetes Mellitus and Recurrent Pregnancy Loss

Roy, T., Das, A., Chatterjee, N., Saha, S. P., Prasad, R., Madan, T., Yasmin, H., & Kishore, U. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1731251 · Cited by 1 · see citing works

Expression of Properdin, the positive regulator of the Complement Alternative Pathway, at the fetal-maternal interface in Preeclampsia

Yasmin, H., Roy, T., Agostinis, C., Rao, A., Sharma, P., Toffoli, M., Balduit, A., Pegoraro, S., Bindu, S., Prasad, R., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1739327 · Cited by 1 · see citing works

Editorial: Macromolecular Structure Underlying Recognition in Innate Immunity

Kishore, U. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00980 · Cited by 1 · see citing works

Pristine and modified nanoparticles : complement activation and immunomodulation

Pondman, K. M. (2014) · doi:10.3990/1.9789036537285 · Cited by 1 · see citing works

The Interplay of Complement Proteins C1q and Factor H

Alrashidi, H. (2016) · Figshare

EXPLORING THE POSSIBLE ROLE OF C3aR LIGATION ON INTESTINAL EPITHELIAL CELLS

McCarthy, J. D. (2014) · DalSpace (Dalhousie University)

Response to Letter to the Editor to Gut microbiota, dietary intakes and intestinal permeability reflected by serum zonulin in women

Mörkl, S., Meinitzer, A., Dschietzig, T. B., Mangge, H., Lackner, S., & Holasek, S. J. (2018) · European Journal of Nutrition · doi:10.1007/s00394-018-1836-5

Role of complement genetic variants in inflammatory diseases by an interactive database and protein structure modelling

Osborne, A. J. (2018) · UCL Discovery (University College London)

Inhibition of the complement anaphylatoxin activities in the central nervous system disorders

Nekrasova, K. A., Ischenko, A. M., & Trofimov, A. V. (2021) · Medical academic journal · doi:10.17816/maj71315

Neutrophil-derived complement factor P induces cytotoxicity in basal-like cells via caspase 3/7 activation in pancreatic cancerPreprint

Kishore, U., Varghese, P. M., Mangogna, A., Klein, L., Tu, M., Urbach, L., Qiu, M., Nicolle, R., Murugaiah, V., Beirag, N., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.10.28.564512

Oxidative Stress Susceptibility, Complement Dysregulation, and Metabolic Reprogramming in CFH Y402H Patient-Derived Choriocapillaris Endothelial CellsPreprint

Rozanska, A. L., Guduric‐Fuchs, J., Pathak, V., Bertelli, P., Teasdale, M., Denton, H., Bhattacharyya, D., Hussain, R., Coxhead, J. M., Kelk, J., et al. (2026) · Research Square · doi:10.21203/rs.3.rs-10140072/v1

C-reactive protein as a potential effector molecule in the pathogenesis of acute post-streptococcal glomerulonephritis: a narrative review

Mojica, Á. A. D., Pedreáñez, A. B., Valero-Cedeño, N., Vargas, R., & Mosquera-Sulbarán, J. (2026) · Pediatric Nephrology · doi:10.1007/s00467-026-07533-x

Complement–Metabolic Inflammation Crosstalk: Molecular Mechanisms and Therapeutic Targets in Type 2 Diabetes and Its Complications

Xie, Y., Wen, Y., Wen, X., Zhang, B., & Zhao, J. (2026) · Current Issues in Molecular Biology · doi:10.3390/cimb48101053

Human liver-derived HEP G2 cells produce functional properdin.

Maves, K. K., & Jm, W. (1994) · PubMed · Cited by 4 · see citing works

The role of properdin and Factor H in disease

Cortés, C., Desler, C., Mazzoli, A., Chen, J. Y., & Ferreira, V. P. (2022) · Advances in immunology · doi:10.1016/bs.ai.2021.12.001 · Cited by 9 · see citing works

Properdin: a tightly regulated critical inflammatory modulator

Blatt, A. Z., Pathan, S., & Ferreira, V. P. (2016) · Immunological Reviews · doi:10.1111/imr.12466 · Cited by 113 · see citing works

Local release of properdin in the cellular microenvironment: role in pattern recognition and amplification of the alternative pathway of complement

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Preferential production and secretion of the complement regulator factor H-like protein 1 (FHL-1) by human myeloid cells

van Essen, M. F., Peereboom, E. T. M., Schlagwein, N., van Gijlswijk‐Janssen, D. J., Nelemans, T., Joeloemsingh, J. V., van den Berg, C. W., Prins, J., Clark, S. J., Schmidt, C. Q., et al. (2023) · Immunobiology · doi:10.1016/j.imbio.2023.152364 · Cited by 4 · see citing works