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Cited by 298

The DOI matches its Crossref record; 198 of the 198 references it cites were found in a registry or an index.

Cross-Talk Between Antigen Presenting Cells and T Cells Impacts Intestinal Homeostasis, Bacterial Infections, and Tumorigenesis

Open access
Gaudino, Stephen J., Kumar, Pawan·2019·Frontiers in Immunology

Abstract

Innate immunity is maintained in part by antigen presenting cells (APCs) including dendritic cells, macrophages, and B cells. APCs interact with T cells to link innate and adaptive immune responses. By displaying bacterial and tumorigenic antigens on their surface via major histocompatibility complexes, APCs can directly influence the differentiation of T cells. Likewise, T cell activation, differentiation, and effector functions are modulated by APCs utilizing multiple mechanisms. The objective of this review is to describe how APCs interact with and influence the activation of T cells to maintain innate immunity during exposure to microbial infection and malignant cells. How bacteria and cancer cells take advantage of some of these interactions for their own benefit will also be discussed. While this review will cover a broad range of topics, a general focus will be held around pathogens, cancers, and interactions that typically occur within the gastrointestinal tract.

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Crossref · 10.3389/fimmu.2019.00360

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Metadata

Authors
Gaudino, S. J., & Kumar, P.
Venue
Frontiers in Immunology
Published
2019-03-06
Volume
10
Pages
360-360
ISSN
1664-3224 (ISSN-L)
OpenAlex
W2921693673
Cited by
298
References
198
FWCI
12.58
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Cross-Talk Between Antigen Presenting Cells and T Cells Impacts Intestinal Homeostasis, Bacterial Infections, and Tumorigenesis. https://app.cochat.ai/papers/10.3389/fimmu.2019.00360
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Gaudino, S. J., & Kumar, P. (2019). Cross-Talk Between Antigen Presenting Cells and T Cells Impacts Intestinal Homeostasis, Bacterial Infections, and Tumorigenesis. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2019.00360

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.