The DOI matches its Crossref record; 341 of the 341 references it cites were found in a registry or an index.
The Role of Monocytes and Macrophages in Autoimmune Diseases: A Comprehensive Review
Open accessAbstract
Monocytes (Mo) and macrophages (Mϕ) are key components of the innate immune system and are involved in regulation of the initiation, development, and resolution of many inflammatory disorders. In addition, these cells also play important immunoregulatory and tissue-repairing roles to decrease immune reactions and promote tissue regeneration. Several lines of evidence have suggested a causal link between the presence or activation of these cells and the development of autoimmune diseases. In addition, Mo or Mϕ infiltration in diseased tissues is a hallmark of several autoimmune diseases. However, the detailed contributions of these cells, whether they actually initiate disease or perpetuate disease progression, and whether their phenotype and functional alteration are merely epiphenomena are still unclear in many autoimmune diseases. Additionally, little is known about their heterogeneous populations in different autoimmune diseases. Elucidating the relevance of Mo and Mϕ in autoimmune diseases and the associated mechanisms could lead to the identification of more effective therapeutic strategies in the future.
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Immunological Responses to Envenomation
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The Immunomodulatory Effects of Statins on Macrophages
Sheridan, A., Wheeler-Jones, C. P. D., & Gage, M. C. (2022) · Immuno · doi:10.3390/immuno2020021 · Cited by 48
Roles of Trained Immunity in the Pathogenesis of Cholangiopathies: A Therapeutic Target
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Metadata
- Authors
- Ma, W.-T., Gao, F., Gu, K., & Chen, D.-K.
- Venue
- Frontiers in Immunology
- Publisher
- Frontiers Media SA
- Published
- 2019-05-24
- Volume
- 10
- Pages
- 1140-1140
- ISSN
- 1664-3224 (ISSN-L)
- OpenAlex
- W2945781043
- Cited by
- 361
- References
- 341
- FWCI
- 13.94
- Type
- journal article
- Language
- en
- Open access
- gold
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