The DOI matches its Crossref record; 260 of the 260 references it cites were found in a registry or an index.
Emerging Concepts and Technologies in Vaccine Development
Open accessAbstract
Despite the success of vaccination to greatly mitigate or eliminate threat of diseases caused by pathogens, there are still known diseases and emerging pathogens for which the development of successful vaccines against them is inherently difficult. In addition, vaccine development for people with compromised immunity and other pre-existing medical conditions has remained a major challenge. Besides the traditional inactivated or live attenuated, virus-vectored and subunit vaccines, emerging non-viral vaccine technologies, such as viral-like particle and nanoparticle vaccines, DNA/RNA vaccines, and rational vaccine design, offer innovative approaches to address existing challenges of vaccine development. They have also significantly advanced our understanding of vaccine immunology and can guide future vaccine development for many diseases, including rapidly emerging infectious diseases, such as COVID-19, and diseases that have not traditionally been addressed by vaccination, such as cancers and substance abuse. This review provides an integrative discussion of new non-viral vaccine development technologies and their use to address the most fundamental and ongoing challenges of vaccine development.
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Cites
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Cited by
The clinical progress of mRNA vaccines and immunotherapies
Barbier, A. J., Jiang, A. Y., Zhang, P., Wooster, R., & Anderson, D. G. (2022) · Nature Biotechnology · doi:10.1038/s41587-022-01294-2 · Cited by 823
Evolution of Cancer Vaccines—Challenges, Achievements, and Future Directions
Tay, B. Q., Wright, Q., Ladwa, R., Perry, C., Leggatt, G., Simpson, F., Wells, J. W., Panizza, B. J., Frazer, I. H., & Cruz, J. L. G. (2021) · Vaccines · doi:10.3390/vaccines9050535 · Cited by 76
Rahman, A., Islam, M. J., Karim, M. R., Kundu, D., & Kabir, S. (2021) · 2021 International Conference on Electronics, Communications and Information Technology (ICECIT) · doi:10.1109/icecit54077.2021.9641303 · Cited by 21
Metadata
- Authors
- Brisse, M., Vrba, S. M., Kirk, N., Liang, Y., & Ly, H.
- Venue
- Frontiers in Immunology
- Publisher
- Frontiers Media SA
- Published
- 2020-09-30
- Volume
- 11
- Pages
- 583077-583077
- ISSN
- 1664-3224 (ISSN-L)
- OpenAlex
- W3089805074
- Cited by
- 323
- References
- 260
- FWCI
- 11.56
- Type
- journal article
- Language
- en
- Open access
- gold
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- Brisse, M., Vrba, S. M., Kirk, N., Liang, Y., & Ly, H. (2020). Emerging Concepts and Technologies in Vaccine Development. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2020.583077
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
