Cited by 340Brain Tumor Detection and ClassificationMedical Image Segmentation TechniquesGlioma Diagnosis and Treatment

Data Augmentation for Brain-Tumor Segmentation: A Review

Open access
Nalepa, Jakub, Marcinkiewicz, Michal, Kawulok, Michal·2019·Frontiers in Computational Neuroscience

Abstract

Data augmentation is a popular technique which helps improve generalization capabilities of deep neural networks, and can be perceived as implicit regularization. It plays a pivotal role in scenarios in which the amount of high-quality ground-truth data is limited, and acquiring new examples is costly and time-consuming. This is a very common problem in medical image analysis, especially tumor delineation. In this paper, we review the current advances in data-augmentation techniques applied to magnetic resonance images of brain tumors. To better understand the practical aspects of such algorithms, we investigate the papers submitted to the Multimodal Brain Tumor Segmentation Challenge (BraTS 2018 edition), as the BraTS dataset became a standard benchmark for validating existent and emerging brain-tumor detection and segmentation techniques. We verify which data augmentation approaches were exploited and what was their impact on the abilities of underlying supervised learners. Finally, we highlight the most promising research directions to follow in order to synthesize high-quality artificial brain-tumor examples which can boost the generalization abilities of deep models.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.3389/fncom.2019.00083

Cites

74 of 74 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

6 of the 80 references couldn’t be matched to a known paper.

Research works printed but not linked: 7

  1. Crimi A. Bakas S. Kuijf H. J. Keyvan F. Reyes M. van Walsum T. (eds). (2019). Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries - 4th International Workshop, BrainLes 2018, Held in Conjunction with MICCAI 2018, Granada, Spain, September 16, 2018, Revised Selected Papers, Part II, volume 11384 of Lecture Notes in Computer Science (Cham).
  2. Feng X. Tustison N. J. Meyer C. H. (2018). “Brain tumor segmentation using an ensemble of 3d u-nets and overall survival prediction using radiomic features,” in Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries - 4th International Workshop, BrainLes 2018, Held in Conjunction with MICCAI 2018, Granada, Spain, September 16, 2018, Revised Selected Papers, Part II, vol. 11384 of Lecture Notes in Computer Science (Cham), 279– 288.
  3. Goodfellow I. Pouget-Abadie J. Mirza M. Xu B. Warde-Farley D. Ozair S. (2014). “Generative adversarial nets,” in Advances in Neural Information Processing Systems 27, eds Ghahramani Z. Welling M. Cortes C. Lawrence N. D. Weinberger K. Q. (Curran Associates, Inc), 2672– 2680. Available online at: http://papers.nips.cc/paper/5423-generative-adversarial-nets.pdf
  4. Isensee F. Kickingereder P. Wick W. Bendszus M. Maier-Hein K. H. (2018). “No new-net,” in Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries - 4th International Workshop, BrainLes 2018, Held in Conjunction with MICCAI 2018, Granada, Spain, September 16, 2018, Revised Selected Papers, Part II, vol. 11384 of Lecture Notes in Computer Science (Cham), 234– 244.
  5. Ma J. Yang X. (2018). “Automatic brain tumor segmentation by exploring the multi-modality complementary information and cascaded 3d lightweight cNNs,” in Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries - 4th International Workshop, BrainLes 2018, Held in Conjunction with MICCAI 2018, Granada, Spain, September 16, 2018, Revised Selected Papers, Part II, vol. 11384 of Lecture Notes in Computer Science (Cham), 25– 36.
  6. Mehta R. Arbel T. (2018). “3D U-Net for brain tumour segmentation,” in Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries - 4th International Workshop, BrainLes 2018, Held in Conjunction with MICCAI 2018, Granada, Spain, September 16, 2018, Revised Selected Papers, Part II, vol. 11384 of Lecture Notes in Computer Science (Cham), 254– 266.
  7. Myronenko A. (2018). “3D MRI brain tumor segmentation using autoencoder regularization,” in Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries - 4th International Workshop, BrainLes 2018, Held in Conjunction with MICCAI 2018, Granada, Spain, September 16, 2018, Revised Selected Papers, Part II, vol. 11384 of Lecture Notes in Computer Science (Cham), 311– 320.

Cited by

Sorted by citations

Authors
Nalepa, J., Marcinkiewicz, M., & Kawulok, M.
Affiliations
Silesian University of Technology (PL)
Corresponding author
Nalepa, Jakub
Venue
Frontiers in Computational Neuroscience
Published
2019-12-11
Volume
13
Pages
83-83
ISSN
1662-5188 (ISSN-L)
OpenAlex
W2992511782
Cited by
340
References
80
Citations by year
2026: 31 · 2025: 42 · 2024: 61 · 2023: 85 · 2022: 66 · 2021: 40 · 2020: 15
FWCI
3.15
Type
journal article
Language
en
Open access
Locations
  • Frontiers in Computational Neuroscience (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Narodowe Centrum Badan i Rozwoju (POIR.01.02.00-00-0030/15)
Topics
  • Life Sciences › Neuroscience › Neurology › Brain Tumor Detection and Classification
  • Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Medical Image Segmentation Techniques
  • Health Sciences › Medicine › Genetics › Glioma Diagnosis and Treatment
Keywords
data augmentation, brain tumor segmentation, magnetic resonance imaging, BraTS 2018, medical image analysis, synthetic data generation, generalization, deep neural network, tumor delineation

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review