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Cited by 269

The DOI matches its Crossref record; 265 of the 265 references it cites were found in a registry or an index.

Chronotype, circadian rhythm, and psychiatric disorders: Recent evidence and potential mechanisms

Open access
Zou, Haowen, Zhou, Hongliang, Yan, Rui, Yao, Zhijian, Lu, Qing·2022·Frontiers in Neuroscience

Abstract

The circadian rhythm is crucial for physiological and behavioral functions. Chronotype, which represents individual preferences for activity and performance, is associated with human health issues, particularly psychiatric disorders. This narrative review, which focuses on the relationship between chronotype and mental disorders, provides an insight into the potential mechanism. Recent evidence indicates that (1) the evening chronotype is a risk factor for depressive disorders and substance use disorders, whereas the morning chronotype is a protective factor. (2) Evening chronotype individuals with bipolar disorder tend to have more severe symptoms and comorbidities. (3) The evening chronotype is only related to anxiety symptoms. (4) The relationship between chronotype and schizophrenia remains unclear, despite increasing evidence on their link. (5) The evening chronotype is significantly associated with eating disorders, with the majority of studies have focused on binge eating disorders. Furthermore, the underlying mechanisms or influence factors are described in detail, including clock genes, brain characteristics, neuroendocrinology, the light/dark cycle, social factors, psychological factors, and sleep disorders. These findings provide the latest evidence on chronotypes and psychiatric disorders and serve as a valuable reference for researchers.

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Metadata

Authors
Zou, H., Zhou, H., Yan, R., Yao, Z., & Lu, Q.
Venue
Frontiers in Neuroscience
Published
2022-08-10
Volume
16
Pages
811771-811771
ISSN
1662-453X (ISSN-L)
OpenAlex
W4290989063
Cited by
269
References
265
FWCI
19.18
Type
journal article
Language
en
Open access
gold
Funders
  • National Natural Science Foundation of China
  • Jiangsu Provincial Key Research and Development Program
  • Jiangsu Provincial Medical Youth Talent
  • Medical Science and Technology Development Foundation, Nanjing Municipality Health Bureau

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CoChat. (2026). Citation check: Chronotype, circadian rhythm, and psychiatric disorders: Recent evidence and potential mechanisms. https://app.cochat.ai/papers/10.3389/fnins.2022.811771
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Zou, H., Zhou, H., Yan, R., Yao, Z., & Lu, Q. (2022). Chronotype, circadian rhythm, and psychiatric disorders: Recent evidence and potential mechanisms. Frontiers in Neuroscience. https://doi.org/10.3389/fnins.2022.811771

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.