Cited by 2,622Mental Health Treatment and AccessChild and Adolescent Psychosocial and Emotional DevelopmentGender Roles and Identity Studies

Gender Differences in Depression in Representative National Samples: Meta-Analyses of Diagnoses and Symptoms

Open access
Salk, Rachel H., Hyde, Janet S., Abramson, Lyn Y.·2017·Psychological Bulletin

Abstract

In 2 meta-analyses on gender differences in depression in nationally representative samples, we advance previous work by including studies of depression diagnoses and symptoms to (a) estimate the magnitude of the gender difference in depression across a wide array of nations and ages; (b) use a developmental perspective to elucidate patterns of gender differences across the life span; and (c) incorporate additional theory-driven moderators (e.g., gender equity). For major depression diagnoses and depression symptoms, respectively, we meta-analyzed data from 65 and 95 articles and their corresponding national data sets, representing data from 1,716,195 and 1,922,064 people in over 90 different nations. Overall, odds ratio (OR) = 1.95, 95% confidence interval (CI) [1.88, 2.03], and d = 0.27 [0.26, 0.29]. Age was the strongest predictor of effect size. The gender difference for diagnoses emerged earlier than previously thought, with OR = 2.37 at age 12. For both meta-analyses, the gender difference peaked in adolescence (OR = 3.02 for ages 13-15, and d = 0.47 for age 16) but then declined and remained stable in adulthood. Cross-national analyses indicated that larger gender differences were found in nations with greater gender equity, for major depression, but not depression symptoms. The gender difference in depression represents a health disparity, especially in adolescence, yet the magnitude of the difference indicates that depression in men should not be overlooked. (PsycINFO Database Record

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Crossref · 10.1037/bul0000102

Cites

272 of 272 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

13 of 92 cited sources checked · 9 supported · 0 flagged · accuracy not yet measured

  • Premisecitation

    In 18 countries from the WHO World Mental Health Surveys, odds ratios for 12-month major depressive episode ranged from 1.2 to 2.7 across 89,037 participants.

    “odds ratios (ORs, female/male) for 12-month major depressive episode (MDE1) ranged from 1.2 to 2.7 across 18 countries and 89,037 participants”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Bromet et al., 2011 source
  • Premisecitation

    The limited findings on adulthood are inconsistent regarding both the magnitude and direction of the gender difference in depression.

    “The limited findings in adulthood are inconsistent with respect to both the magnitude and direction of the gender difference in depression”
    Quote in the paperSubstantial claim1 of 3 sources checked
    • cites Angst et al., 2002 source
    • cites Mirowsky, 1996 source
    • cites Oksuzyan et al., 2010 source

      The Results (Depression) and Discussion describe variation by country and age, including a slight reversal in Japan that was not statistically significant. But the paper studies middle and older ages, not adulthood broadly, and its Discussion says the literature generally finds higher depression prevalence in women from young adulthood through early old age. It does not support characterizing the limited findings across adulthood as inconsistent in direction. (LLM, conf=0.84)

      Experimental — accuracy not yet measured
  • Premisecitation

    The limited research on ethnicity, gender, and depression in the United States does not indicate variation by ethnicity in the gender difference in depression.

    “The limited research on ethnicity, gender, and depression in the United States does not indicate variation by ethnicity in the gender difference in depression”
    Quote in the paperSubstantial claim1 of 3 sources checked
    • cites Barnes et al., 2013 source

      The Results section (‘Tests of interaction in NESARC data’; page unavailable) reports a non-significant race × sex interaction (P = 0.89), consistent with no detected Black–White variation in the sex difference in lifetime major depression. The study tests Black and White respondents, not ethnicity broadly, and says it lacked sufficient power to test the interaction for 12-month depression. (LLM, conf=0.86)

      Experimental — accuracy not yet measured
    • cites Breslau et al., 2006

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites Oquendo et al., 2001 source
  • Premisecitation

    Other research indicates that economic development is not a major factor in cross-national variations in the magnitude of gender differences in depression.

    “This absence of any substantial effect for nation-level wealth is consistent with other research (Bromet et al., 2011) indicating that economic development is not a major factor in cross-national variations in the magnitude of gender differences in depression.”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites Bromet et al., 2011 source
  • Findingown data

    Cross-national analyses indicated no relationship between gender equity and gender differences in depression symptoms.

    “Cross-national analyses indicated that larger gender differences were found in nations with greater gender equity, for major depression, but not depression symptoms.”
    Quote in the paperSubstantial claim
    • The authors state this as an assumption: The domain-specific gender equity indicators chosen are theoretically linked to gender differences in depression.
  • Classified as probably not a substantial claim. 72
  • May combine two claims. 101
  • Borderline: one of the tests for a substantial claim is unclear. 1
  • Not yet classified. 1
  • Classified as probably not a substantial claim.

    Premisecitation

    A study including 18 countries from the WHO World Mental Health Surveys reported that the relationship between gender and major depressive episode did not differ significantly between high-income and low- to middle-income countries.

    “A study including 18 countries from the WHO World Mental Health Surveys (Kessler & Usten, 2008) reported that the relationship between gender and MDE did not differ significantly between high-income and low- to middle-income countries”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Bromet et al., 2011 source
  • May combine two claims.

    Premisecitation

    The 2-to-1 ratio for major depression is not universal and may vary substantially across nations.

    “However, findings also suggest that the 2:1 ratio is not universal and may vary substantially across nations.”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Bromet et al., 2011 source
  • May combine two claims.

    Premisecitation

    In most adult epidemiological reports, women have higher rates of major depression than men, with an average ratio of 2 to 1.

    “In the vast majority of epidemiological reports on adults, women have higher rates of major depression compared to men; on average, the ratio is 2:1”
    Quote in the paperSubstantial claim1 of 2 sources checked
    • cites Andrade et al., 2003 source
    • cites Bromet et al., 2011 source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Other widely held beliefs about gender differences, such as the gender difference in math performance, have sometimes been found inaccurate when meta-analyzed.

    “Other widely held beliefs about gender differences, such as the gender difference in math performance, have sometimes been found to be inaccurate when the data are meta-analyzed”
    Quote in the paperNot a substantial claim1 of 2 sources checked
    • cites Hyde et al., 2008

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites Lindberg et al., 2010 source
  • Classified as probably not a substantial claim. May combine two claims.

    Premisecitation

    There is increased recognition of the validity and value of dimensional assessments, as well as the impairment associated with sub-threshold symptoms that do not meet diagnostic criteria.

    “there is increased recognition of the validity (e.g., Markon, Chmielewski, & Miller, 2011) and value (Cuthbert & Insel, 2013) of dimensional assessments, as well as the impairment associated with sub-threshold levels of symptoms that do not meet diagnostic criteria.”
    Quote in the paperSubstantial claim1 of 2 sources checked
    • cites Markon et al., 2011 source
    • cites Cuthbert & Insel, 2013 source
  • May combine two claims.

    Premisecitation

    Two large multi-nation studies reported conflicting results, finding that the gender gap in depression was smaller and larger, respectively, in low gender-equity countries compared to high gender-equity countries.

    “Two large multi-nation studies have reported conflicting results, finding that the gender gap in depression was smaller and larger, respectively, in low gender-equity countries compared to high gender-equity countries”
    Quote in the paperSubstantial claim1 of 2 sources checked
    • cites Hopcroft & Bradley, 2007 source
    • cites Van de Velde et al., 2013 source

      The Discussion reports the conflicting finding that Hopcroft and Bradley found a larger depression gender gap in high-equality countries, while this paper's results were more consistent with equality reducing women's disadvantage. But the Results say the overall interaction between gender and equality was not significant; a smaller gap at higher equality appeared only in certain subgroups and for certain measures. The sentence overstates this paper's finding as a general cross-country result. (LLM, conf=0.87)

      Experimental — accuracy not yet measured
  • Classified as probably not a substantial claim.

    Premisecitation

    Seedat and colleagues found a significant narrowing in the gender difference in depression in recent cohorts.

    “Seedat and colleagues (2009) found a significant narrowing in the gender difference in depression in recent cohorts.”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Seedat et al., 2009 source
  • May combine two claims.

    Premisecitation

    A latent growth curve analysis found that girls' depression symptoms accelerated early in adolescence and then leveled off, while boys' symptoms accelerated in late adolescence.

    “One latent growth curve analysis indicated that girls’ depression symptoms accelerated early in adolescence and then leveled off, whereas boys’ symptom levels accelerated in late adolescence (Salk, Petersen, Abramson, & Hyde, 2016), consistent with the first possibility above.”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites Salk, Petersen, Abramson, & Hyde, 2016 source
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    Greater contraceptive prevalence should indicate women's greater reproductive control and a lower rate of unwanted pregnancies, which are a risk factor for depression.

    “On the face of it, greater contraceptive prevalence should indicate women’s greater control over reproduction and a lower rate of unwanted pregnancies, which are a risk factor for depression (e.g., Mercier, Garrett, Thorp, & Siega-Riz, 2013).”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites Mercier, Garrett, Thorp, & Siega-Riz, 2013 source

      The Discussion (Main Findings) reports that women with unwanted pregnancies had a higher risk of postpartum depression than women with intended pregnancies. The claim says “depression” without limiting it to the postpartum period; the paper also cautions in the Discussion (Interpretation) that it cannot establish a causal relationship. The contraceptive-prevalence premise appears to be the citing authors’ framing, not a finding attributed to this source. (LLM, conf=0.82)

      Experimental — accuracy not yet measured
  • Borderline on S3 (load-bearing), S4 (based): unclear from the text.

    Findingnone given

    In both meta-analyses, U.S. ethnicity did not account for significant variation in effect size.

    “In both meta-analyses, U.S. ethnicity did not account for significant variation in effect size (see Table 4).”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The meta-analysis of depression symptoms pooled 95 articles and their national datasets, covering 1,922,064 individuals from more than 90 countries.

    “we meta-analyzed data from 65 and 95 articles and their corresponding national datasets, representing data from 1,716,195 and 1,922,064 people in over 90 different nations.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    For both meta-analyses, the gender difference declined after adolescence and remained stable in adulthood.

    “but then declined and remained stable in adulthood.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    The meta-analysis of major depression diagnoses pooled 65 articles and their national datasets, covering 1,716,195 individuals from more than 90 countries.

    “we meta-analyzed data from 65 and 95 articles and their corresponding national datasets, representing data from 1,716,195 and 1,922,064 people in over 90 different nations.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    The gender difference for major depression diagnoses emerged earlier than previously thought, with an odds ratio of 2.37 at age 12.

    “The gender difference for diagnoses emerged earlier than previously thought, with OR = 2.37 at age 12.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Findingown data

    Overall, 112 articles from the original search met inclusion criteria, and 46 new articles were added from additional searching for nationally representative datasets.

    “Overall, 112 articles from the original search met criteria for inclusion, including articles for which authors needed to be contacted for data. We added 46 new articles that were not in the original search from additional searching for nationally representative datasets.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    Effect sizes for ages 8-12 (0.09), 13-15 (0.35), and 16-19 (0.41) were statistically different (QB = 23.01 and QB = 8.06, ps < .01), with each consecutive age group significantly larger than the previous one.

    “Follow-up testing with pairs of consecutive age groups indicated that the effect sizes for ages 8–12 (0.09), 13–15 (0.35), and 16–19 (0.41) were statistically different (QB = 23.01 and QB = 8.06, ps< .01, respectively), such that the effect size for each consecutively age group was significantly larger than the previous age group.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Findingown data

    The depression symptom meta-analysis covers data collected from 1978 to 2014, while the major depression meta-analysis covers data collected from 1991 to 2014.

    “The depression symptom meta-analysis covers data collected from 1978–2014 whereas the major depression meta-analysis only includes data collected from 1991–2014.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    For major depression, effect sizes ranged from OR = 1.71 to OR = 3.02, with ORs above 2.0 during adolescence and between 1.71 and 2.02 in adulthood.

    “Effect sizes ranged from OR = 1.71 to OR = 3.02, with ORs >2.0 during adolescence and ORs between 1.71 and 2.02 in adulthood.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Findingown data

    In the major depression meta-analysis, 96% of articles reported DSM major depression diagnoses or episodes and 4% reported the roughly equivalent ICD-10 depressive episode.

    “For the major depression meta-analysis, all articles reported DSM major depression diagnoses or episodes (96%) or the roughly equivalent ICD-10 depressive episode (4%).”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    The random effects variance component for the major depression meta-analysis was 0.07.

    “The random effects variance component was 0.07.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The youngest age group available for the major depression analyses was 12 years old, so the emergence of the gender difference from childhood to adolescence could not be observed.

    “Note that the youngest age group available for these analyses was 12 years old, making it impossible to observe the emergence of the gender difference from childhood to adolescence.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Findingown data

    When outliers were removed, income category became marginally significant (QB = 3.09, p = 0.08), with smaller gender differences in high-income nations (d = 0.26) than in low- to middle-income nations (d = 0.29).

    “However, when outliers were removed, the effect became marginally significant (QB = 3.09, p = 0.08) with smaller gender differences in high-income nations (d = 0.26) compared to low- to middle- income nations (d = 0.29).”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    The random effects variance component for the depression symptom meta-analysis was 0.02.

    “The random effects variance component was 0.02.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    Although the likelihood ratio test showed a marginal effect for the major depression meta-analysis, the weighted averages from the unadjusted model (logged OR = 0.67) and adjusted model (logged OR = 0.62) were quite similar.

    “Although the LRT showed a marginal effect for the major depression meta-analysis, the weighted average from the unadjusted model (logged OR = 0.67) and the adjusted model (logged OR = 0.62) were quite similar.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Findingown data

    The symptom studies were published between 1991 and 2016, with data collected from 1978 to 2014 in 53 countries.

    “These studies were published from 1991 to 2016 and yielded data from 1978–2014 collected from 53 different countries.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The 95 symptom articles provided data comprising 180 samples, 413 effect sizes, and 1,922,064 people, of whom 52% were female.

    “utilized data comprising 180 samples, 413 effect sizes, and 1,922,064 people (52% female).”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Findingown data

    Both meta-analyses include mostly high-income countries and cover the lifespan.

    “They both include mostly high-income countries and cover the lifespan.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The OR at ages 16-19 (2.69) was significantly larger than the OR at ages 20-29 (1.93), QB = 43.19, p < .001, indicating a significant decrease in the gender difference from adolescence to the 20s.

    “The OR at ages 16–19 (2.69) was significantly larger than the OR for ages 20–29 (1.93), QB = 43.19, p < .001, indicating a significant decrease in the gender difference from adolescence to the 20s.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    Removing outliers did not change the effect size estimates for depression symptoms.

    “Removal of outliers did not change the estimates of effect sizes.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    Likelihood ratio tests comparing unadjusted and adjusted models for the major depression and depression symptom meta-analyses were not statistically significant (p = 0.073 and p = 0.3226, respectively).

    “The likelihood ratio tests (LRT) comparing the unadjusted to adjusted models (using p-value cut points of 0.05, 0.01, and 0.001) for the major depression and depression symptom meta-analyses, respectively, were not statistically significant, p = 0.073 and p = 0.3226.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingcitation

    The literacy variable was not range restricted, with ratios from .31 to 1.07.

    “Importantly, there was not a range restriction for the literacy variable (ratios ranged from .31 to 1.07), which can have substantial negative skew (Else-Quest & Grabe, 2012).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Else-Quest & Grabe, 2012 source
  • May combine two claims.

    Findingown data

    For major depression, contraceptive prevalence and literacy ratio both predicted variability in effect size.

    “Contraceptive prevalence and literacy ratio both predicted variability in effect size.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    The two meta-analyses differ in the distribution of nations and years of data collection.

    “However, they differ in terms of the distribution of nations and year of data collection.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    In the symptom meta-analysis, most effect sizes were based on the CES-D measure.

    “For the symptom meta-analysis, most effect sizes were based on the C ES-D measure.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    In follow-up analyses, effect sizes from gender-focused articles did not differ significantly from those focused on depression (QB = 2.22, p = 0.14) or on something other than gender or depression (QB = 0.91, p = 0.34).

    “However, in follow-up analyses, effect sizes from articles that focused on gender were not significantly different than effect sizes from articles that focused on depression (QB = 2.22, p = 0.14) or something other than gender or depression (QB = 0.91, p =0.34).”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Findingown data

    The diagnosis studies were published between 1993 and 2016, with data collected from 1991 to 2014 in 75 countries.

    “These studies were published from 1993 to 2016 with data from 1991–2014 collected in 75 different countries.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The 65 diagnosis articles provided data comprising 149 samples, 300 effect sizes, and 1,716,195 people, of whom 53% were female.

    “provided data comprising 149 samples (this number includes different countries from the same international dataset as well as different years of data collection for cross-sectional national datasets), 300 effect sizes (this number includes separate effect sizes for different age groups and ethnicities), and 1,716,195 people (53% female).”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    Most effect sizes in the major depression meta-analysis were 12-month major depressive episodes based on DSM-IV or DSM-IV-TR using a version of the CIDI.

    “The vast majority of effect sizes for the major depression meta-analysis were 12-month major depressive episodes based on the DSM-IV or DSM-IV-TR using a version of the CIDI.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    When outliers were excluded, the OR for ages 13-15 decreased from 3.02 to 2.92 and the OR for age 70+ increased from 2.02 to 2.20.

    “When outliers were excluded, the age 13–15 OR decreased from 3.02 to 2.92 and the age 70+ OR increased from 2.02 to 2.20.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    The depression symptom meta-analysis includes the most effect sizes from Europe (53%).

    “and the depression symptom meta-analysis includes the most effect sizes from Europe (53%).”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    For depression symptoms, effect sizes ranged from d = 0.09 to d = 0.41, peaked at ages 16-19, declined in the 20s, and remained relatively stable at about d = 0.20 thereafter.

    “Effect sizes ranged from d = 0.09 to d = 0.41, peaking at ages 16–19, declining in the 20s, and staying relatively stable at roughly d = 0.20 after that.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Findingown data

    The diagnosis meta-analysis included 65 articles and their datasets, and the symptom meta-analysis included 95 articles and their datasets.

    “The final sample of studies (see Figure 1) for the meta-analyses included data from 65 (diagnosis meta-analysis) and 95 (symptom meta-analysis) articles and their corresponding data sets.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Findingown data

    For depression symptoms, income inequality was a significant predictor, with larger gender differences reported in nations with low income inequality.

    “Income inequality was a significant predictor of effect size, such that larger gender differences were reported in nations with low levels of income inequality.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    In the major depression meta-analysis, diagnostic manual, type of depression (episode versus disorder), and depression time span did not predict effect size variation.

    “As shown in Table 4, manual for major depression (e.g., DSM-IV, ICD-10), type of depression (episode versus disorder) and depression time span (1 month, 6 months, 12 months, and lifetime) did not predict effect size variation.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    In both meta-analyses, the gender difference in depression peaked during adolescence, then declined and remained stable in adulthood.

    “For both meta-analyses, the effect size peaked in adolescence but then declined and remained stable in adulthood, a finding that has not been identified previously.”
    • Also stated in: § Conclusions · boosted
      “Our results provide powerful evidence that the gender difference in major depression diagnoses and depression symptoms peaks in adolescence, with the gender gap in diagnoses emerging earlier than previously thought (OR = 2.37 at age 12). The gender gap then narrows and remains stable in adulthood, a finding that has not been identified previously and has important implications for both theory and”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    In both meta-analyses, the gender difference declined in early adulthood and then remained relatively stable, with odds ratios between 1.71 and 2.02 and d values between 0.19 and 0.30.

    “In both meta-analyses, the gender difference declined in early adulthood and then remained relatively stable, hovering between OR = 1.71 – 2.02 and d = 0.19 – 0.30.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    When expressed as Cohen's d, the effect sizes for major depression and depression symptoms are similar: d = 0.37 and d = 0.27, respectively.

    “Expressed in the Cohen’s d metric, the two effect sizes are similar: d = 0.37 for major depression and d = 0.27 for depression symptoms.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    In our meta-analysis, the odds ratio for ages 13-15 was 3.02 and declined to 2.69 for ages 16-19.

    “The odds ratio for the 13–15 age group in our meta-analysis was already 3.02 and declined, not widened, to OR = 2.69 for ages 16–19.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    Categorical year-of-data-collection estimates for major depression were: 1991-1996 = 1.84 (k = 22); 1997-2002 = 1.88 (k = 134); 2003-2008 = 1.91 (k = 59); 2009-2014 = 2.17 (k = 85).

    “To better understand this pattern, we created a categorical variable for year of data collection and obtained the following effect size estimates: 1991–1996= 1.84, k = 22; 1997–2002= 1.88, k = 134; 2003–2008= 1.91, k = 59; 2009–2014 = 2.17, k = 85.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    In the major depression meta-analysis, the youngest age studied was 12, and the odds ratio at that age was already 2.37.

    “In the major depression meta-analysis, we could not examine the emergence of the gender difference given that the youngest age in the studies was 12, when the OR was already 2.37.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    Across different subgroups, every odds ratio for major depression diagnoses exceeded 1.0 and every effect size for depression symptoms was positive.

    “That is, among different subgroups, all odds ratios for diagnoses were > 1.0, and all effect sizes for symptoms were positive.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    For depression symptoms, contraceptive prevalence, executive positions, and literacy ratio did not predict variation in effect size.

    “Contraceptive prevalence, executive positions, and the literacy ratio did not predict variation in effect size.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    In follow-up analyses excluding outliers, diagnoses using ICD were significantly smaller than those using DSM-IV/DSM-IV-TR (QB = 6.86, p < .01) and DSM-III/DSM-III-R (QB = 9.60, p < .01).

    “Follow up analyses, excluding outliers, indicated that diagnoses using the ICD were significantly smaller than both diagnoses using DSM-IV/DSM-IV-TR (QB = 6.86, p < .01) and DSM-III/ DSM- III-R TR (QB = 9.60, p < .01).”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    In the symptom meta-analysis, the gender difference was trivial at ages 8-11, then increased steeply and peaked at age 16.

    “In the symptom meta-analysis, the gender difference emerged in adolescence with a trivial gender difference for ages 8–11 (see Figure 3) and then a steep increase, reaching a peak in the gender difference at age 16.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    In follow-up tests, all pairwise comparisons were significantly different, with the smallest effect size for the BDI (d = 0.20) and the largest for scales other than the BDI and CES-D (d = 0.31).

    “In follow-up tests, all pair-wise comparisons were significantly different from each other, such that the smallest effect size was for the BDI (d = 0.20) and the largest effect size was for scales other than the BDI and CES-D (d = 0.31).”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    Income inequality had no relation to the gender effect size for diagnoses; it was negatively related for symptom measures but lost significance when outliers were excluded.

    “However, there was no relation to the gender effect size for diagnoses; it was negatively related for symptom measures but lost significance when outliers were excluded.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    In both the diagnosis and symptom meta-analyses, differences among U.S. ethnic groups were not significant.

    “In both the diagnosis and symptom meta-analyses, differences among ethnic groups were not significant.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The symptom meta-analysis found no significant trend over time, while the diagnosis meta-analysis found a positive trend indicating growing gender differences.

    “The symptom meta-analysis found no significant trend over time and the diagnosis meta-analysis found a positive trend, meaning that gender differences are growing larger.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    The finding of larger gender differences in nations with greater gender equity did not replicate in the symptom meta-analysis, so caution is needed in interpreting the diagnosis findings.

    “These findings of larger gender differences in nations with greater gender equity did not replicate with the meta-analysis of depression symptoms, suggesting that caution is needed in interpreting the findings for diagnoses.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Other studies have found smaller gender differences in nations with more gender inequality for outcomes such as self-reports of personality traits and attitudes about mathematics.

    “However, other studies have found smaller gender differences in nations with more gender inequality. This pattern has been found for outcomes such as self-reports of personality traits and attitudes about mathematics”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites Else-Quest et al., 2010 source
    • cites Wood & Eagly, 2012 source
  • May combine two claims.

    Premisecitation

    That meta-analysis was limited to the Children's Depression Inventory scale and samples of 8- to 16-year-old participants in the United States and Canada, with n = 43,916.

    “it was limited to the Children’s Depression Inventory (CDI; Kovacs, 1985) scale and samples of 8- to 16-year-old participants in the United States and Canada (n = 43,916).”
    Quote in the paperSubstantial claim0 of 2 sources checked
    • cites Twenge & Nolen-Hoeksema, 2002 source
    • cites Kovacs, 1985

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • Classified as probably not a substantial claim.

    Premisecitation

    Social-structural theory predicts that larger gender differences should be observed in nations with more gender inequality.

    “The theory predicts that larger gender differences should be observed in nations with more gender inequality.”
    Quote in the paperSubstantial claim0 of 2 sources checked
    • cites Eagly & Wood, 1999

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites Wood & Eagly, 2012 source
  • Classified as probably not a substantial claim. May combine two claims.

    Premisecitation

    Hankin and colleagues found that the gender difference in clinical depression emerged by ages 13 to 15 and then widened between ages 15 and 18.

    “Hankin and colleagues (1998) found that the gender difference in clinical depression emerged by ages 13–15 and then widened between ages 15 and 18.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Hankin et al., 1998 source
  • Classified as probably not a substantial claim.

    Premisecitation

    According to social-structural theory, a society's division of labor by gender drives all other psychological gender differences.

    “According to the theory, a society’s division of labor by gender drives all other psychological gender differences.”
    Quote in the paperSubstantial claim0 of 2 sources checked
    • cites Eagly & Wood, 1999

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites Wood & Eagly, 2012 source
  • Classified as probably not a substantial claim.

    Premisecitation

    Developmental psychopathology theories contend that multiple pathways to the gender difference in depression involve combinations and interactions of risk factors across multiple levels of analysis.

    “Theories of developmental psychopathology contend that there are multiple pathways to the gender difference in depression involving combinations and interactions of risk factors that span multiple levels of analysis”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Cicchetti & Rogosch, 2002 source
  • May combine two claims.

    Premisecitation

    In childhood, there is no gender difference or even a somewhat higher prevalence of depression among boys than girls.

    “there is no gender difference or even a somewhat higher prevalence of depression among boys than girls in childhood”
    Quote in the paperSubstantial claim0 of 2 sources checked
    • cites Avenevoli et al., 2008
    • cites Twenge & Nolen-Hoeksema, 2002 source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Evidence for social-structural theory exists for several psychological gender differences, including mate preferences, mathematics performance, and some aspects of sexuality.

    “Evidence for this theory exists for several psychological gender differences, including mate preferences, mathematics performance, and some aspects of sexuality”
    Quote in the paperNot a substantial claim0 of 3 sources checked
    • cites Eagly & Wood, 1999

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites Else-Quest et al., 2010 source
    • cites Petersen & Hyde, 2010 source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    To the extent that women report higher rates of violent victimization, this may contribute to the gender difference in depression.

    “To the extent that women report higher rates of violent victimization, this may contribute to the gender difference in depression”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Koss et al., 1994 source
  • Classified as probably not a substantial claim.

    Premisecitation

    The female preponderance in depression is thought to emerge by ages 13 to 15.

    “The female preponderance in depression is thought to emerge by ages 13–15”
    Quote in the paperSubstantial claim0 of 3 sources checked
    • cites Hankin et al., 1998 source
    • cites Twenge & Nolen-Hoeksema, 2002 source
    • cites Wichstrøm, 1999 source
  • May combine two claims.

    Premisecitation

    Gender inequality is linked to discrimination against women, which may contribute to the gender difference in depression.

    “gender inequality is linked to discrimination against women, which may contribute to the gender difference”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Belle & Doucet, 2003 source
  • Classified as probably not a substantial claim. May combine two claims.

    Premisecitation

    Theories highlight that specific vulnerability factors come online at critical developmental periods in adolescence and/or interact with stressors in adolescence to produce the gender difference in adolescence.

    “Theories highlight how specific vulnerability factors come on-line at critical developmental periods in adolescence and/or interact with stressors in adolescence to produce the gender difference in adolescence”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Hyde et al., 2008b

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Premisecitation

    Adolescents and adults with subthreshold depression symptoms and minor depression experience significant impairment and are at elevated risk for later major depression and suicidal behaviors.

    “adolescents and adults with subthreshold depression symptoms and minor depression still experience significant impairment (e.g., Lewinsohn, Solomon, Seeley, & Zeiss, 2000) and are at elevated risk for later development of major depression and suicidal behaviors”
    Quote in the paperSubstantial claim0 of 3 sources checked
    • cites Lewinsohn et al., 2000 source
    • cites Cuijpers et al., 2004

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites Fergusson et al., 2005 source
  • May combine two claims.

    Premisecitation

    The extant literature indicates that the prevalence of major depression in the United States varies both by gender and by ethnicity.

    “The extant literature indicates that the prevalence of major depression in the United States varies both by gender and by ethnicity”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Breslau et al., 2006

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    One recent narrative review concluded that internalizing problems for girls increased from the late 20th century to the 21st century.

    “One recent narrative review concluded that internalizing problems for girls increased from the late 20th century to the 21st century”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Bor et al., 2014 source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductcitation

    The authors followed MARS reporting standards.

    “we follow MARS reporting standards”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites American Psychological Association Publications and Communications Board, 2008

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • Classified as probably not a substantial claim.

    Study design and conductreasoning

    To maintain independence of samples, when a sample was used in more than one article, the authors selected the article with the most complete data and/or the largest sample size.

    “If a particular sample of participants was used in more than one article, which was often the case with these national datasets, to maintain independence of samples, we selected the article that had the most complete data (including information on moderator variables such as age and ethnicity) and/or the largest sample size.”
    Quote in the paperSubstantial claim
  • Classified as probably not a substantial claim.

    Study design and conductreasoning

    For nationally representative longitudinal studies with multiple waves, only one wave of data was included to maintain independence of samples.

    “For nationally representative longitudinal studies with multiple waves of data (e.g., Add Health), we included only one wave of data to maintain independence of samples.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Study design and conductown data

    Interrater agreement was κ = .87 for type of depression diagnosis and κ = 1.00 for time span of the depression diagnosis.

    “type of depression diagnosis (depressive episode versus depressive disorder), κ = .87; and (4) the time span for the depression diagnosis (current, 1 month, 6 months, 12 months, lifetime), κ = 1.00.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Study design and conductreasoning

    All datasets were nationally representative, which minimizes sampling bias.

    “First, all datasets were nationally representative, indicating that any bias in sampling is minimized.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Study design and conductown data

    For the diagnosis meta-analysis, author-provided data were obtained for 24 of 65 articles (37%), and 167 of 300 effect sizes (56%) were based on obtained rather than published data.

    “For the meta-analysis on depression diagnoses, we received data from authors for 24 (37%) of the 65 articles, such that 167 (56%) of the 300 effect sizes were based on obtained rather than published data.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductown data

    The intimate-partner violence and sexism ideals measures were not considered further because they were available for only a minority of effect sizes.

    “Although they were theoretically interesting, the intimate-partner violence and sexism ideals measures proved unsatisfactory because they were available for only a minority of the effect sizes in analyses. Those two measures are therefore not considered further.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductnone given

    Data were entered into the effect size calculator by two individuals to ensure accuracy.

    “Data were entered in the calculator by two individuals to ensure accuracy.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductown data

    Interrater agreement for article focus was κ = .84.

    “we coded the focus of the article (gender, depression, other), κ = .84.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim.

    Premisecitation

    Hedges and Nowell argued that the strongest scientific evidence about gender differences comes from larger studies based on representative samples of populations, not small convenience samples.

    “They argued that the strongest scientific evidence about gender differences does not come from small studies of convenience samples, but instead comes from larger studies based on representative samples of populations.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Hedges & Nowell, 1995 source
  • Classified as probably not a substantial claim.

    Study design and conductnone given

    Abstracts were included only if they explicitly mentioned "nationally representative."

    “We included abstracts that explicitly mentioned “nationally representative.””
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Study design and conductown data

    Interrater agreement was κ = 1.0 for the type of measure used to assess depression and for the diagnostic manual used.

    “the type of measure used to assess depression diagnoses (diagnostic interview; e.g., CIDI, DIS) or depression symptoms (self-report measure; e.g., CES-D, BDI), κ = 1.0; (2) the manual used to diagnose depression (DSM-IV or DSM-IV-TR5; DSM-III or DSM-III-R; or ICD-10), κ = 1.0”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Study design and conductown data

    For the symptom meta-analysis, author-provided data were obtained for 71 of 95 articles (75%), and 357 of 413 effect sizes (86%) were based on obtained data.

    “For the meta-analysis on depression symptoms, we received data from authors for 71 (75%) of the 95 articles, such that 357 (86%) of the 413 effect sizes were based on obtained data.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Study design and conductown data

    Interrater agreement was high for age (r = .99), country (κ = 1.00), U.S. ethnic group (κ = 1.00), and year of data collection (r = 1.00).

    “age of the participants (measured on a continuous scale, using the reported mean or the midpoint of the age range), r = .99”
    • Also stated in: § Coding of Studies · plain
      “country, κ (kappa) = 1.00”
    • Also stated in: § Coding of Studies · plain
      “predominant (≥ 85%) ethnic group of participants (Caucasian, African American, Asian American, Hispanic, Native American, other, mixed, or unreported), κ = 1.00; and (d) year of data collection, r = 1.00.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim. May combine two claims.

    Premisecitation

    A meta-analysis of gender differences in self-esteem found a small difference favoring Caucasian males over Caucasian females, d = 0.20, but no gender difference for African American samples, d = −0.04.

    “a meta-analysis of gender differences in self-esteem found a small difference favoring Caucasian males over Caucasian females, d = 0.20, but no gender difference for African American samples, d = −0.04”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Kling et al., 1999 source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductown data

    The authors contacted study authors for whom email addresses could be found to obtain missing data.

    “all authors of the study for whom we could find email addresses from the article, the Web directory of the authors’ academic institution, or a Google search, were contacted.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim.

    Study design and conductnone given

    Studies were excluded if their depression symptom measure did not meet criteria: at least 3 items, self-report, Cronbach's alpha ≥ .70 if provided, and a valid and reliable measure based on previously published research.

    “Studies were excluded if their measurement of depression symptoms did not meet the following criteria: 1) minimum of 3 items; 2) self-report; 3) Cronbach’s alpha ≥.70 (if provided); and 4) valid and reliable measure of depression based on previously published research”
    Quote in the paperSubstantial claim
  • Classified as probably not a substantial claim. May combine two claims.

    Study design and conductnone given

    Studies were excluded if they were not based on national probability sampling; only population-based surveys representative of the country were included.

    “we excluded studies that were not based on national probability sampling. In other words, we included only population-based surveys representative of the country.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductown data

    Thirty studies were double coded to compute interrater agreement.

    “We double coded 30 studies to compute interrater agreement.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Study design and conductreasoning

    Data for the economic and gender equity indicators were not available for all nations, so sample sizes varied across regression analyses depending on the indicator.

    “For each of the economic and gender equity indicators, data are not available for all nations. Therefore, sample sizes vary in regression analyses, depending on the indicator.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Study design and conductreasoning

    Raw effect sizes were corrected for small-sample bias, and most correction factors were close to 1.0 because sample sizes were large.

    “Raw effect sizes were corrected for bias (i.e., the upward-bias of effect sizes among small samples; Hedges, 1981); however, most correction factors were close to 1.0 given the large sample sizes.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Hedges, 1981 source
  • May combine two claims.

    Interpretationown data

    Because most studies were published on depression rather than on gender differences, publication bias favoring gender differences should not be a problem.

    “This indicates that most studies were published on the basis of the work on depression and not on the basis of a gender difference, so publication bias in the direction of gender differences should not be a problem.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    The Hedges and Nowell strategy has been used in other meta-analyses on gender differences in cognitive abilities.

    “The Hedges and Nowell strategy has since been used in other meta-analyses on gender differences in cognitive abilities”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites Else-Quest et al., 2010 source
    • cites Reilly et al., 2015 source
  • Classified as probably not a substantial claim.

    Study design and conductnone given

    Studies were excluded if their measurement of depression diagnoses did not include a diagnostic interview with the participant.

    “Studies were excluded in the processing of articles if their measurement of depression diagnoses did not include a diagnostic interview with the participant.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductnone given

    All analyses were run with the full dataset and then re-run with outliers excluded.

    “All analyses were run with the full data set and then re-run excluding outliers.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim. May combine two claims.

    Interpretationreasoning

    Stressors tied to major life transitions are spread more evenly across adulthood, leading to more even depression rates across age for both genders and a stable gender gap.

    “The result is that stressors attached to these transitions are spread out more evenly across adulthood, leading to more even rates of depression across age for both women and men, and a stable gender gap.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Interpretationown data

    Although the range of ORs from 1.84 to 2.17 is not large, the positive relationship between year of data collection and the gender difference in major depression is clear.

    “Thus, although the range of OR = 1.84 to 2.17 is not great, the positive relationship is clear.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationown data

    Our results provide powerful evidence that the gender difference in depression emerges earlier than previously thought, by at least age 12 for diagnoses and at age 12 for symptoms.

    “Taken together, our results provide powerful evidence that the gender difference in depression emerges earlier than previously thought (by at least age 12 for diagnoses, at age 12 for symptoms), which has important implications for the timing of preventive interventions.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    Hankin and colleagues (1998) found that the gender gap in major depression emerged between ages 13 and 15 and widened between ages 15 and 18.

    “These results differ from those of Hankin and colleagues (1998), who found that that the gender gap in major depression emerged between ages 13 and 15 and then widened between ages 15 and 18.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Hankin and colleagues (1998)

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Interpretationown data

    The adult pattern is a new finding and should be robust because it comes from large-scale meta-analyses and was consistent across diagnosis and symptom measures.

    “This pattern is a new finding and should be robust because it is based on large-scale meta-analyses and was consistent across both diagnosis and symptom measures.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).

    Premisenone given

    Individuals high in negative affectivity and low in positive affectivity are vulnerable to later depression.

    “In particular, individuals who are high in negative affectivity and low on positive affectivity are vulnerable to later depression.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Interpretationreasoning

    According to the cognitive vulnerability-stress model, the adolescent gender difference in depression may be explained by higher negative cognitive style in girls, higher stress in girls, or both.

    “According to this model, the gender difference in depression in adolescence may be accounted for by (a) higher levels of negative cognitive style in girls than boys beginning in early adolescence; (b) higher levels of stress for girls than boys beginning in early adolescence; or (c) both.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationown data

    Females consistently show higher levels of major depression and depression symptoms than males.

    “This emphasizes the consistency with which females have higher levels major depression and depression symptoms than males.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    One theoretical account holds that early puberty is disadvantageous for girls but not boys for outcomes such as depression.

    “According to one theoretical account, early puberty is disadvantageous for girls but not boys, for outcomes such as depression (Ge, Conger, & Elder, 2001).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Ge, Conger, & Elder, 2001 source
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Interpretationreasoning

    The difference between our findings and earlier meta-analytic findings may be due to more recent studies, more nations, or multiple symptom measures.

    “The difference in findings may be due to the greater recency of many of our studies, the greater number of nations, or the inclusion of multiple measures of depression symptoms.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Depression is a recurrent disorder.

    “A third possibility results from the observation that depression is a recurrent disorder (e.g., Lewinsohn, Rohde, Seeley, Klein, & Gotlib, 2000).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Lewinsohn, Rohde, Seeley, Klein, & Gotlib, 2000 source
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Interpretationreasoning

    Men may be less likely than women to develop depression, but depressed men are still distressed and impaired.

    “Men may be less likely to develop depression than women; however, this does not mean that depressed men are not distressed and impaired.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Study design and conductown data

    Gender equity measures were missing for some nations, so the analyses did not capture patterns among all included nations.

    “Second, gender equity measures were missing for some nations; thus, the analyses did not capture patterns among all nations included.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    One theoretical account holds that temperament, present from infancy and early childhood, predicts later depression.

    “According to one theoretical account, temperament, present from infancy and early childhood, predicts later depression (summarized by Hyde et al., 2008b).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Hyde et al., 2008b

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    In the 21st century, women make up 47% of the U.S. labor force, compared with 30% in 1950.

    “For example, in the 21st century women constitute 47% of the U.S. labor force, compared to 30% in 1950 (Costello et al., 2003).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Costello et al., 2003

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Premisecitation

    Negative cognitive style may not become a stable trait until ages 9.5 to 12.5, and the cognitive vulnerability-stress interaction may not reliably predict depression until ages 13.5 to 14.5.

    “Research suggests that negative cognitive style may not emerge as a stable trait until ages 9.5 to 12.5, and the cognitive vulnerability-stress interaction does not become a reliable predictor of depression until ages 13.5 to 14.5, i.e., in early adolescence (Cole et al., 2008).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Cole et al., 2008 source
  • May combine two claims.

    Premisecitation

    The gender difference in depression is created at least in part by early-puberty girls, through processes such as encountering more peer sexual harassment than boys and on-time girls.

    “Thus the gender difference in depression is created at least in part by girls who go through puberty early, because of any of several processes, such as early-puberty girls encountering more peer sexual harassment than boys and on-time girls (Lindberg, Grabe, & Hyde, 2007).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Lindberg, Grabe, & Hyde, 2007 source
  • May combine two claims.

    Premisecitation

    Symptom assessments typically cover a short period such as a week, while diagnoses aggregate over longer periods such as a year.

    “For example, the typical assessment of symptoms often represents a short period of time, such as a week, whereas diagnoses involve aggregation over longer periods, often a year (Haeffel et al., 2003).”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Haeffel et al., 2003 source
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Interpretationreasoning

    Most first cases of depression may occur in adolescence and then recur at variable times in adulthood because of the uneven timing of major stressors.

    “As such, it may be that most first cases of depression occur in adolescence, and then recur at variable times in adulthood, as a result of the uneven timing of major stressors.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Premisecitation

    Theories guided by developmental psychopathology have focused on the emergence of the gender difference in adolescence but have not attended to development across adulthood.

    “As noted earlier, theories guided by developmental psychopathology have focused on explaining the emergence of the gender difference in adolescence (summarized by Hyde et al., 2008b), but did not attend to development across adulthood.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Hyde et al., 2008b

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Interpretationreasoning

    An odds ratio of 1.95 is a medium rather than large effect size, but it still represents a health disparity.

    “An OR of 1.95 is a medium, not a large, effect size, yet it is still a health disparity.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Premisecitation

    Another theoretical account rests on cognitive vulnerability-stress models of depression, which have been well supported in college student and adult samples.

    “Another theoretical account rests on cognitive vulnerability-stress models of depression, which have been well supported in samples of college students and adults (summarized by Hyde et al., 2008b).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Hyde et al., 2008b

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Interpretationreasoning

    Prevalence would remain stable across adulthood for both women and men, producing a stable gender gap created by the original adolescent gap.

    “Again, prevalence would remain stable across adulthood for both women and men, leading to a stable gender gap, created by the original gender gap in adolescence.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Depression is a global health priority.

    “Given that depression is a global health priority (World Health Organization, 2016), it is imperative to understand disparities in depression and which subgroups are most in need of services.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites World Health Organization, 2016

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Interpretationnone given

    Assuming equal numbers of males and females, an odds ratio of 2.0 can result from a 9.05% female and 4.85% male prevalence, or from an 18% female and 10.1% male prevalence.

    “For example, assuming equal numbers of males and females, an OR = 2.0 can result from a 9.05% prevalence in females and a 4.85% prevalence in males, or from an 18% prevalence in females and a 10.1% prevalence in males.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Premisecitation

    Evidence indicates high reliability between clinicians and lay interviewers; for major depressive disorder, kappa was 0.97 with 99.7% agreement.

    “Results indicated high agreement between the two; for major depressive disorder, kappa = 0.97, with 99.7% agreement between the two sources (see also Brugha, Nienhuis, Bagchi, Smith, & Meltzer, 1999).”
    Quote in the paperSubstantial claim0 of 2 sources checked
    • cites Wittchen, Robins, Cottler, Sartorius, Burke, & Regier, 1991 source
    • cites Brugha, Nienhuis, Bagchi, Smith, & Meltzer, 1999 source
  • Classified as probably not a substantial claim.

    Study design and conductnone given

    The authors made extensive efforts to obtain data for as many national data sets as possible by conducting additional computerized searches and contacting authors.

    “We also made extensive efforts to obtain data for as many national data sets as possible by conducting additional computerized searches and contacting authors.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Interpretationreasoning

    Mounting a nationally representative study is a major, costly undertaking that should almost certainly result in multiple publications, at least one in English, so such studies should have been detected.

    “Moreover, mounting a study based on a nationally representative sample is a major, costly undertaking that should almost certainly result in multiple publications, at least one of them in English, so we should have detected such studies.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationown data

    Gender differences were larger in nations with more gender equity, a finding consistent across three indicators.

    “That is, perhaps counterintuitively, gender differences were larger in nations with more gender equity, a finding that was consistent across three indicators.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The nation-level indicators of gender equity and national wealth validly measure those constructs.
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductreasoning

    Because the study focused on large nationally representative datasets, diagnostic interviews were conducted by trained lay interviewers rather than skilled clinicians, as is standard in such epidemiological studies.

    “Second, focusing on large, nationally representative datasets meant that the diagnostic interviews for major depression were conducted not by skilled clinicians, but instead by trained lay interviewers, as is standard practice in these large-scale, epidemiological studies.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim. May combine two claims.

    Study design and conductnone given

    Both diagnostic measures and symptom questionnaire measures rely on self-reports from participants.

    “Third, both diagnostic measures and symptom questionnaire measures rely on self-reports from participants.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Some primary studies have found patterns similar to ours regarding gender differences and gender equity for outcomes such as self-construals and emotion.

    “Yet, as noted in the introduction, some primary studies have found similar patterns to ours regarding gender differences and gender equity, for outcomes such as self-construals (Guimond et al., 2007) and emotion (Fischer, Rodriguez Mosquera, van Vianen, & Manstead, 2004).”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites Guimond et al., 2007 source
    • cites Fischer, Rodriguez Mosquera, van Vianen, & Manstead, 2004 source
  • Classified as probably not a substantial claim.

    Premisecitation

    Guimond and colleagues (2007) proposed that gender differences in self-construals are larger when individuals make intergroup social comparisons.

    “Guimond and colleagues (2007) proposed that gender differences in self-construals are larger in contexts in which individuals make intergroup social comparisons, e.g., when they compare themselves to an out-group such as the other gender.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Guimond and colleagues (2007)

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Interpretationown data

    These results suggest that women worldwide are at significantly greater risk of depression diagnoses and symptoms than men, and that adolescent girls are at greatest risk.

    “These results suggest that women are at significantly greater risk of depression diagnoses and symptoms compared to men worldwide, and that adolescent girls are at the greatest risk.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Study design and conductown data

    By synthesizing nationally representative studies with over 1.7 million participants each, the two meta-analyses provide a comprehensive quantitative review of gender differences in major depression diagnoses and depression symptoms across the lifespan.

    “By synthesizing nationally representative studies with data from over 1.7 million participants spanning the globe in each of the two meta-analyses, we have provided a comprehensive quantitative review of data on gender differences in major depression diagnoses and depression symptoms across the lifespan.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The nationally representative samples included in the meta-analyses accurately represent their target national populations.
  • May combine two claims.

    Interpretationreasoning

    In higher gender-equity nations, where males and females interact more, intergroup comparisons are likelier, leading to larger gender differences.

    “It is precisely in higher gender-equity nations, where males and females interact more (e.g., girls are more literate because they have more equal access to schooling with boys), that intergroup comparisons are likelier, leading to larger gender differences.”
    Quote in the paperSubstantial claim
  • Classified as probably not a substantial claim.

    Study design and conductnone given

    The database search included only articles in English.

    “Fourth, our database search included only articles in English.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Study design and conductown data

    The ethnic-group analyses were based on small numbers of studies, so power to detect ethnic-group differences was limited.

    “These analyses, however, were based on small numbers of studies. Therefore, power to detect ethnic-group differences was limited.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Interpretationcitation

    In low-gender-equity nations, intergroup interactions are often restricted, and gender differences on variables such as depression are smaller because comparisons are mostly intragroup.

    “In low-gender-equity nations, intergroup interactions are often greatly restricted, and gender differences on a variable such as depression are smaller due to mostly intragroup comparisons.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Study design and conductown data

    The authors did not have sufficient data to examine gender differences in major depression for children younger than age 12, and had only 2 samples for age 12, even though the minimum age criterion was 7.

    “First, we did not have sufficient data to examine gender differences in major depression for children younger than age 12 (and we had only 2 samples for age 12), even though the minimum age criterion was 7.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Interpretationreasoning

    If there are gender differences in willingness to disclose symptoms, then the resulting data may be biased.

    “If there are gender differences in willingness to disclose symptoms, then the resulting data may be biased.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationown data

    The difference between the high-income and other-nation odds ratios is small, with overlapping 95% confidence intervals, suggesting it is not a major effect.

    “However, the difference between these odds ratios is small, and the 95% confidence intervals overlap, suggesting that this difference is not a major effect.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S1 (asserted), S3 (load-bearing).

    Premisecitation

    One early review concluded that the gender difference in depression is a real difference and not a measurement artifact.

    “One early review concluded that the gender difference in depression is a real difference and not a measurement artifact (Weissman & Klerman, 1977).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Weissman & Klerman, 1977

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Interpretationreasoning

    The authors believe that the English-only search did not lead to the omission of nations in which English is not the predominant language, for two reasons.

    “We believe that this did not lead to the omission of nations in which English is not the predominant language for two reasons.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Premisecitation

    Depression is a recurring disorder, so an episode in adolescence can predispose an individual to later episodes.

    “The emphasis on adolescents is particularly important because depression is a recurring disorder, so an episode in adolescence can predispose the individual to later episodes (e.g., Lewinsohn, Rohde, Seeley, Klein, & Gotlib, 2000).”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Lewinsohn, Rohde, Seeley, Klein, & Gotlib, 2000 source
  • May combine two claims.

    Interpretationreasoning

    The gender difference in depression is a major health disparity, especially in adolescence, but the magnitude of the difference indicates that depression in males should not be overlooked.

    “The gender difference in depression represents a major health disparity, especially in adolescence, yet the magnitude of the difference indicates that depression in males should not be overlooked.”
    Quote in the paperSubstantial claim
  • Not yet classified.

    Study design and conduct

    Overall, 76% of symptom effect sizes and 56% of diagnosis effect sizes were based on data supplied by researchers rather than published articles, reducing concerns about publication bias.

    “Overall, 76% of the effect sizes for the symptom meta-analysis and 56% of the effect sizes for the diagnosis meta-analysis were based on data supplied by researchers, and not published in articles, reducing concerns about publication bias.”
    Quote in the paperNot yet classified
146 of 146
  • The paper relies on this without support.

    The existing literature on gender differences in depression had not been meta-analytically synthesized before this study.

    “this large body of sometimes inconsistent research has yet to be synthesized meta-analytically.”
  • The authors state this as an assumption.

    The domain-specific gender equity indicators chosen are theoretically linked to gender differences in depression.

    “We selected domain-specific indicators of gender equity (rather than composite indicators) that should, theoretically, be tied to gender differences in depression”
  • The authors state this as an assumption.

    The mixed-effects model used for moderator analyses assumes that variability among effect sizes beyond subject-level sampling error has both systematic components (accounted for by moderator variables) and random components (error variance).

    “The mixed-effects model assumes that variability among effects sizes beyond subject-level sampling error has both systematic components (accounted for by moderator variables) and random components (i.e., error variance).”
  • The paper relies on this without support.

    The nationally representative samples included in the meta-analyses accurately represent their target national populations.

    “By synthesizing nationally representative studies with data from over 1.7 million participants spanning the globe in each of the two meta-analyses, we have provided a comprehensive quantitative review of data on gender differences in major depression diagnoses and depression symptoms across the lifespan.”
  • The paper relies on this without support.

    The nation-level indicators of gender equity and national wealth validly measure those constructs.

    “For major depression diagnoses, variability in the gender difference in depression was linked to measures of national wealth and gender equity.”
5 of 5

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Women are more likely than males to experience recurring MDD and are twice as likely to experience MDD throughout their lifetimes.

    “Women are more likely than males to experience recurring MDD 445 and are twice as likely to experience MDD throughout their lifetimes. 446”

    From Major depressive disorder: hypothesis, mechanism, prevention and treatment (2024) · cites this paper as [446]

    The Results (Magnitude of the Gender Difference in Depression) report higher odds of major-depression diagnoses for females (OR = 1.95), and Results (Additional Moderators) say the gender difference did not vary significantly by diagnostic time span, including lifetime. The Discussion (Developmental Pattern) describes depression as recurrent in both women and men, but does not establish that women are more likely than men to experience recurrence. The paper also notes that the roughly twofold gender difference is an average, not universal. (LLM, conf=0.86)

    Experimental — accuracy not yet measured
  • The risk of certain mental health problems such as depression, self-harm, and eating disorders is higher in adolescent females than in males.

    “and the risk of certain mental health problems such as depression, self-harm, and eating disorders is higher in adolescent females than in males27.”

    From Windows of developmental sensitivity to social media (2022) · cites this paper as [27]

    The Discussion’s Developmental Pattern section reports that the gender difference in depression peaks in adolescence, supporting the depression portion of the claim. The paper does not establish that adolescent females have higher risks of self-harm or eating disorders than males; its Background mentions suicidal behaviors only as a possible later risk associated with subthreshold depression. (LLM, conf=0.90)

    Experimental — accuracy not yet measured
  • In old analyses, females have more symptoms, diagnoses, or feelings of depression in countries with higher living conditions.

    “Considering studies from only the old analyses, we found that females have more symptoms, diagnoses, or feelings of depression in countries with higher living conditions (Hopcroft & Bradley, 2007; Hopcroft & McLaughlin, 2012; Salk et al., 2017; Seedat et al., 2009; Van de Velde et al., 2013; Wang et al., 2016).”

    From A Systematic Review and New Analyses of the Gender-Equality Paradox (2025) · cites this paper as Salk et al., 2017

    In Results, under “Nation-level economic indicators” (page not provided), the paper reports a larger female–male difference in major-depression diagnoses in high-income countries. It does not support the same pattern for symptoms: income category was not a significant predictor, and an outlier-sensitive analysis suggested a slightly smaller difference in high-income countries. The quoted passage does not establish a separate finding about feelings of depression. (LLM, conf=0.90)

    Experimental — accuracy not yet measured
  • Females have higher rates of depression than males in most studies, with SMDs of 0.19-0.38.

    “As has often been reported, females have in most studies been found to have higher rates of Depression (SMDs = 0.19–0.38; Hopcroft & Bradley, 2007; Hopcroft & McLaughlin, 2012; Salk et al., 2017; Seedat et al., 2009; Van de Velde et al., 2013; Wang et al., 2016).”

    From A Systematic Review and New Analyses of the Gender-Equality Paradox (2025) · cites this paper as Salk et al., 2017

  • Sex and sedentary screen time are associated with depression symptoms.

    “Given the well-established associations of sex and sedentary screen time with depression symptoms, 43,44”

Statistics recomputed

Every reported test result, recomputed from its test statistic and degrees of freedom. A result shows as not adding up only once an independent check has confirmed it.

  • Consistentt(299) = 1961.63reported p < .001 · recomputed p < .001

    “t(299) = 1961.63, p < .001”

  • Consistentt(412) = 9542.5reported p < .001 · recomputed p < .001

    “t(412) = 9542.50, p < .001”

2 of 2

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

Each contradiction between two passages listed here was confirmed by an independent check.

  • Conflicting percentages for researcher-supplied symptom data

    Minor

    The results state that 357 of 413 symptom effect sizes (86%) came from data obtained from authors, but the limitations section gives 76% for the same category.

1 of 1

Cites

Flagged first, then by citations

4 of the 276 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Authors
Salk, R. H., Hyde, J. S., & Abramson, L. Y.
Affiliations
University of Wisconsin–Madison (US)
Venue
Psychological Bulletin
Published
2017-08
Volume
143
Issue
8
Pages
783-822
ISSN
  • 0033-2909 (ISSN-L)
  • 1939-1455
OpenAlex
W2609632515
Cited by
2,622
References
276
Citations by year
2026: 352 · 2025: 420 · 2024: 403 · 2023: 354 · 2022: 388 · 2021: 308 · 2020: 261 · 2019: 93 · 2018: 31 · 2017: 8 · 2014: 1
FWCI
153.86
Type
journal article
Language
en
Open access
Locations
  • Psychological Bulletin (publishedVersion, other-oa)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Science Foundation (DGE-071823; DRL 1138114)
  • National Institute of Mental Health (T32 MH018269-30)
  • University of Wisconsin-Madison
Topics
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
  • Social Sciences › Gender Studies › Gender Roles and Identity Studies
Keywords
gender differences, depression, depressive symptoms, adolescence, lifespan development, gender equity, cross-national comparison, health disparities, men's mental health
MeSH terms
Adolescent, Adult, Aged, Depression, Major Depressive Disorder, Female, Gender Identity, Humans, Male, Middle Aged, Sex Factors, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Claims read under definition version 3 (extract-v3) on 2026-09-28.

Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-09-28.

Cited sources are checked by gpt-6-sol.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

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