Flux-Balance Modeling of Plant Metabolism

Reactive oxygen species: Metabolism, oxidative stress, and signal transduction

Apel, K., & Hirt, H. (2004) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.55.031903.141701 · Cited by 11,723 · see citing works

GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox

Philip Zimmermann, B., Hirsch‐Hoffmann, M., Hennig, L., & Gruissem, W. (2004) · PLANT PHYSIOLOGY · doi:10.1104/pp.104.046367 · Cited by 2,463 · see citing works

Optknock: A bilevel programming framework for identifying gene knockout strategies for microbial strain optimization

Burgard, A. P., Pharkya, P., & Maranas, C. D. (2003) · Biotechnology and Bioengineering · doi:10.1002/bit.10803 · Cited by 1,262 · see citing works

Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors

Butelli, E., Titta, L., Giorgio, M., Mock, H.-P., Matros, A., Peterek, S., Schijlen, E. G. W. M., Hall, R. D., Bovy, A. G., Luo, J., et al. (2008) · Nature Biotechnology · doi:10.1038/nbt.1506 · Cited by 1,238 · see citing works

The effects of alternate optimal solutions in constraint-based genome-scale metabolic models

Mahadevan, R., & Schilling, C. H. (2003) · Metabolic Engineering · doi:10.1016/j.ymben.2003.09.002 · Cited by 1,203 · see citing works

A High-Resolution Root Spatiotemporal Map Reveals Dominant Expression Patterns

Brady, S. M., Orlando, D. A., Lee, J., Wang, J. Y., Koch, J. D., Dinneny, J. R., Mace, D., Ohler, U., & Benfey, P. N. (2007) · Science · doi:10.1126/science.1146265 · Cited by 1,154 · see citing works

High-throughput generation, optimization and analysis of genome-scale metabolic models

Henry, C. S., DeJongh, M., Best, A. A., Frybarger, P. M., Linsay, B., & Stevens, R. L. (2010) · Nature Biotechnology · doi:10.1038/nbt.1672 · Cited by 1,090 · see citing works

Coordination of carbon supply and plant growth

Smith, A. M., & Stitt, M. (2007) · Plant Cell & Environment · doi:10.1111/j.1365-3040.2007.01708.x · Cited by 1,028 · see citing works

Dynamic flux balance analysis of diauxic growth in Escherichia coli

Mahadevan, R., Edwards, J. S., & Doyle, F. J. (2002) · Biophysical Journal · doi:10.1016/s0006-3495(02)73903-9 · Cited by 945 · see citing works

Products, requirements and efficiency of biosynthesis a quantitative approach

de Vries, F. W. T. P., Brunsting, A. H. M., & van Laar, H. H. (1974) · Journal of Theoretical Biology · doi:10.1016/0022-5193(74)90119-2 · Cited by 912 · see citing works

ROS in biotic interactions

Torres, M. Á. M. (2009) · Physiologia Plantarum · doi:10.1111/j.1399-3054.2009.01326.x · Cited by 903 · see citing works

Not just a circle: flux modes in the plant TCA cycle

Sweetlove, L. J., Beard, K. F. M., Nunes‐Nesi, A., Fernie, A. R., & Ratcliffe, R. G. (2010) · Trends in Plant Science · doi:10.1016/j.tplants.2010.05.006 · Cited by 878 · see citing works

The <i>Escherichia coli</i> MG1655 <i>in silico</i> metabolic genotype: Its definition, characteristics, and capabilities

Edwards, J. S., & Palsson, B. O. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.10.5528 · Cited by 875 · see citing works

The oxidative pentose phosphate pathway: structure and organisation

Kruger, N. J., & von Schaewen, A. (2003) · Current Opinion in Plant Biology · doi:10.1016/s1369-5266(03)00039-6 · Cited by 838 · see citing works

The McCree-de Wit-Penning de Vries-Thornley respiration paradigms: 30 years later.

Amthor, J. (2000) · Annals of Botany · doi:10.1006/anbo.2000.1175 · Cited by 822 · see citing works

Systematic evaluation of objective functions for predicting intracellular fluxes in Escherichia coli

Schuetz, R. J., Kuepfer, L., & Sauer, U. (2007) · Molecular Systems Biology · doi:10.1038/msb4100162 · Cited by 684 · see citing works

Raising yield potential of wheat. II. Increasing photosynthetic capacity and efficiency.

Parry, M., Reynolds, M., Salvucci, M., Raines, C., Andralojc, P., Zhu, X.-G., Price, G., Condon, A., & Furbank, R. (2011) · Journal of Experimental Botany · doi:10.1093/jxb/erq304 · Cited by 646 · see citing works

From zero to hero—Design-based systems metabolic engineering of Corynebacterium glutamicum for l-lysine production

Becker, J., Zelder, O., Häfner, S., Schröder, H., & Wittmann, C. (2011) · Metabolic Engineering · doi:10.1016/j.ymben.2011.01.003 · Cited by 594 · see citing works

Experimental Analysis of the Arabidopsis Mitochondrial Proteome Highlights Signaling and Regulatory Components, Provides Assessment of Targeting Prediction Programs, and Indicates Plant-Specific Mitochondrial Proteins [W]

Heazlewood, J. L., Tonti‐Filippini, J., Gout, A. M., Day, D. A., Whelan, J., & Millar, A. H. (2004) · The Plant Cell · doi:10.1105/tpc.016055 · Cited by 575 · see citing works

A Small Family of MYB -Regulatory Genes Controls Floral Pigmentation Intensity and Patterning in the Genus Antirrhinum

Schwinn, K. E., Venail, J., Shang, Y., Mackay, S., Alm, V., Butelli, E., Oyama, R. K., Bailey, P. C. E., Davies, K. M., & Martin, C. R. (2006) · The Plant Cell · doi:10.1105/tpc.105.039255 · Cited by 574 · see citing works

Metabolomics-assisted breeding: a viable option for crop improvement?

Fernie, A. R., & Schauer, N. (2009) · Trends in Genetics · doi:10.1016/j.tig.2008.10.010 · Cited by 550 · see citing works

Transgenic multivitamin corn through biofortification of endosperm with three vitamins representing three distinct metabolic pathways

Naqvi, S., Zhu, C., Farré, G., Ramessar, K., Bassié, L., Breitenbach, J., Conesa, D. P., Ros, G., Sandmann, G., Capell, T., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0901412106 · Cited by 525 · see citing works

Design and analysis of synthetic carbon fixation pathways

Bar‐Even, A., Noor, Ε., Lewis, N. E., & Milo, R. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0907176107 · Cited by 509 · see citing works

The Calvin cycle revisited

Raines, C. A. (2003) · Photosynthesis Research · doi:10.1023/a:1022421515027 · Cited by 494 · see citing works

Evaluation of transgenic tomato plants expressing an additional phytoene synthase in a fruit-specific manner

Fraser, P. D., Römer, S., Shipton, C. A., Mills, P. B., Kiano, J. W., Misawa, N., Drake, R., Schuch, W., & Bramley, P. M. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.241374598 · Cited by 483 · see citing works

Genome-Scale Proteomics Reveals Arabidopsis thaliana Gene Models and Proteome Dynamics

Baerenfaller, K., Grossmann, J., Grobei, M. A., Hull, R., Hirsch‐Hoffmann, M., Yalovsky, S., Zimmermann, P., Grossniklaus, U., Gruissem, W., & Baginsky, S. (2008) · Science · doi:10.1126/science.1157956 · Cited by 483 · see citing works

Rubisco without the Calvin cycle improves the carbon efficiency of developing green seeds

Schwender, J., Goffman, F. D., Ohlrogge, J. B., & Shachar‐Hill, Y. (2004) · Nature · doi:10.1038/nature03145 · Cited by 471 · see citing works

Flux balance analysis of primary metabolism in Chlamydomonas reinhardtii

Boyle, N. R., & Morgan, J. A. (2009) · BMC Systems Biology · doi:10.1186/1752-0509-3-4 · Cited by 455 · see citing works

Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli

Alper, H. S., Jin, Y., Moxley, J. F., & Stephanopoulos, G. N. (2005) · Metabolic Engineering · doi:10.1016/j.ymben.2004.12.003 · Cited by 450 · see citing works

SUBA: the Arabidopsis Subcellular Database

Heazlewood, J. L., Verboom, R. E., Tonti‐Filippini, J., Small, I., & Millar, A. H. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl863 · Cited by 428 · see citing works

Group Contribution Method for Thermodynamic Analysis of Complex Metabolic Networks

Jankowski, M. D., Henry, C. S., Broadbelt, L. J., & Vassily Hatzimanikatis, A. (2008) · Biophysical Journal · doi:10.1529/biophysj.107.124784 · Cited by 379 · see citing works

AraGEM, a Genome-Scale Reconstruction of the Primary Metabolic Network in Arabidopsis

de Oliveira Dal'Molin, C. G., Quek, L.-E., Palfreyman, R. W., Brumbley, S. M., & Nielsen, L. K. (2010) · Plant Physiology · doi:10.1104/pp.109.148817 · Cited by 353 · see citing works

Metabolic control and regulation of the tricarboxylic acid cycle in photosynthetic and heterotrophic plant tissues.

Araújo, W., Nunes-Nesi, A., Nikoloski, Z., Sweetlove, L., & Fernie, A. (2012) · Plant, Cell and Environment · doi:10.1111/j.1365-3040.2011.02332.x · Cited by 330 · see citing works

Stoichiometric model of Escherichia coli metabolism: Incorporation of growth‐rate dependent biomass composition and mechanistic energy requirements

Pramanik, J., & Keasling, J. D. (1997) · Biotechnology and Bioengineering · doi:10.1002/(sici)1097-0290(19971120)56:4 · Cited by 329 · see citing works

Metabolic engineering of the mevalonate and non‐mevalonate isopentenyl diphosphate‐forming pathways for the production of health‐promoting isoprenoids in tomato

Enfissi, E. M. A., Fraser, P. D., Lois, L. M., Boronat, A., Schuch, W., & Bramley, P. M. (2004) · Plant Biotechnology Journal · doi:10.1111/j.1467-7652.2004.00091.x · Cited by 326 · see citing works

Thirteen Years of Building Constraint-Based In Silico Models of Escherichia coli

Reed, J. L., & Palsson, B. Ø. (2003) · Journal of Bacteriology · doi:10.1128/jb.185.9.2692-2699.2003 · Cited by 302 · see citing works

A Genome-Scale Metabolic Model of Arabidopsis and Some of Its Properties

Poolman, M. G., Miguet, L., Sweetlove, L. J., & Fell, D. A. (2009) · PLANT PHYSIOLOGY · doi:10.1104/pp.109.141267 · Cited by 297 · see citing works

A Flux Model of Glycolysis and the Oxidative Pentosephosphate Pathway in Developing Brassica napus Embryos

Schwender, J., Ohlrogge, J. B., & Shachar‐Hill, Y. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303432200 · Cited by 270 · see citing works

Measuring multiple fluxes through plant metabolic networks

Ratcliffe, R. G., & Shachar‐Hill, Y. (2006) · The Plant Journal · doi:10.1111/j.1365-313x.2005.02649.x · Cited by 261 · see citing works

Large-scale in silico modeling of metabolic interactions between cell types in the human brain

Lewis, N. E., Schramm, G., Bordbar, A., Schellenberger, J., Andersen, M. P., Cheng, J. K., Patel, N., Yee, A., Lewis, R. A., Eils, R., et al. (2010) · Nature Biotechnology · doi:10.1038/nbt.1711 · Cited by 261 · see citing works

The role of light in soybean seed filling metabolism

Allen, D. K., Ohlrogge, J. B., & Shachar‐Hill, Y. (2008) · The Plant Journal · doi:10.1111/j.1365-313x.2008.03771.x · Cited by 225 · see citing works

Recursive MILP model for finding all the alternate optima in LP models for metabolic networks

Lee, S.-B., Phalakornkule, C., Domach, M. M., & Grossmann, I. E. (2000) · Computers & Chemical Engineering · doi:10.1016/s0098-1354(00)00323-9 · Cited by 216 · see citing works

Compartmentation in plant metabolism

Lunn, J. E. (2006) · Journal of Experimental Botany · doi:10.1093/jxb/erl134 · Cited by 206 · see citing works

Flux Balance Analysis of Photoautotrophic Metabolism

Shastri, A. A., & Morgan, J. A. (2005) · Biotechnology Progress · doi:10.1021/bp050246d · Cited by 205 · see citing works

Energy use efficiency is characterized by an epigenetic component that can be directed through artificial selection to increase yield

Hauben, M., Haesendonckx, B., Standaert, E., Kelen, K. V. D., Azmi, A., Akpo, H., Breusegem, F. V., Guisez, Y., Bots, M., Lambert, B., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0908755106 · Cited by 203 · see citing works

Zea mays iRS1563: A Comprehensive Genome-Scale Metabolic Reconstruction of Maize Metabolism

Saha, R., Suthers, P. F., & Maranas, C. D. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021784 · Cited by 201 · see citing works

Metabolic Networks: How to Identify Key Components in the Regulation of Metabolism and Growth

Stitt, M., Ronan Sulpice, A., & Keurentjes, J. J. B. (2009) · PLANT PHYSIOLOGY · doi:10.1104/pp.109.150821 · Cited by 201 · see citing works

C4GEM, a Genome-Scale Metabolic Model to Study C4 Plant Metabolism

Dal’Molin, C. G. D. O., Quek, L., Palfreyman, R. W., Brumbley, S. M., & Nielsen, L. K. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.166488 · Cited by 201 · see citing works

The Metabolic Network of Synechocystis sp. PCC 6803: Systemic Properties of Autotrophic Growth

Knoop, H., Zilliges, Y., Lockau, W., & Steuer, R. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.157198 · Cited by 195 · see citing works

Is maximization of molar yield in metabolic networks favoured by evolution?

Schuster, S., Pfeiffer, T., & Fell, D. A. (2007) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2007.12.008 · Cited by 184 · see citing works

The Metabolic Response of Arabidopsis Roots to Oxidative Stress is Distinct from that of Heterotrophic Cells in Culture and Highlights a Complex Relationship between the Levels of Transcripts, Metabolites, and Flux

Lehmann, M., Schwarzländer, M., Obata, T., Sirikantaramas, S., Burow, M., Olsen, C. E., Tohge, T., Fricker, M. D., Møller, B. L., Fernie, A. R., et al. (2008) · Molecular Plant · doi:10.1093/mp/ssn080 · Cited by 177 · see citing works

Carbon conversion efficiency and central metabolic fluxes in developing sunflower (Helianthus annuus L.) embryos

Alonso, A. P., Goffman, F. D., Ohlrogge, J. B., & Shachar‐Hill, Y. (2007) · The Plant Journal · doi:10.1111/j.1365-313x.2007.03235.x · Cited by 161 · see citing works

Analysis of Metabolic Flux Phenotypes for Two Arabidopsis Mutants with Severe Impairment in Seed Storage Lipid Synthesis

Lonien, J., & Schwender, J. (2009) · PLANT PHYSIOLOGY · doi:10.1104/pp.109.144121 · Cited by 160 · see citing works

Flux Balance Analysis of Barley Seeds: A Computational Approach to Study Systemic Properties of Central Metabolism

Grafahrend‐Belau, E., Schreiber, F., Dirk Koschützki, A., & Junker, B. H. (2008) · PLANT PHYSIOLOGY · doi:10.1104/pp.108.129635 · Cited by 159 · see citing works

Quantification of Compartmented Metabolic Fluxes in Developing Soybean Embryos by Employing Biosynthetically Directed Fractional 13C Labeling, Two-Dimensional [13C, 1H] Nuclear Magnetic Resonance, and Comprehensive Isotopomer Balancing

Sriram, G., Fulton, D. B., Iyer, V. V., Peterson, J. M., Zhou, R., Westgate, M. E., Spalding, M. H., & Shanks, J. V. (2004) · PLANT PHYSIOLOGY · doi:10.1104/pp.104.050625 · Cited by 159 · see citing works

Metabolic flux analysis in plants: coping with complexity

Allen, D. K., Libourel, I. G. L., & Shachar‐Hill, Y. (2009) · Plant Cell & Environment · doi:10.1111/j.1365-3040.2009.01992.x · Cited by 152 · see citing works

Cytosolic pyruvate,orthophosphate dikinase functions in nitrogen remobilization during leaf senescence and limits individual seed growth and nitrogen content

Taylor, L. E., Nunes‐Nesi, A., Parsley, K., Leiss, A., Leach, G., Coates, S. A., Wingler, A., Fernie, A. R., & Hibberd, J. M. (2010) · The Plant Journal · doi:10.1111/j.1365-313x.2010.04179.x · Cited by 150 · see citing works

Metabolic control analysis and regulation of the conversion of sucrose to starch in growing potato tubers

Geigenberger, P., Stitt, M. D., & Fernie, A. R. (2004) · Plant Cell & Environment · doi:10.1111/j.1365-3040.2004.01183.x · Cited by 146 · see citing works

Two-Phase Resolution of Polyploidy in theArabidopsisMetabolic Network Gives Rise to Relative and Absolute Dosage Constraints

Bekaert, M., Edger, P. P., Pires, J. C., & Conant, G. C. (2011) · The Plant Cell · doi:10.1105/tpc.110.081281 · Cited by 140 · see citing works

A Genome-Scale Metabolic Model Accurately Predicts Fluxes in Central Carbon Metabolism under Stress Conditions

Williams, T. C. R., Poolman, M. G., Howden, A. J. M., Schwarzländer, M., Fell, D. A., Ratcliffe, R. G., & Sweetlove, L. J. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.158535 · Cited by 138 · see citing works

Unraveling the complexity of flux regulation: A new method demonstrated for nutrient starvation in Saccharomyces cerevisiae

Rossell, S., van der Weijden, C. C., Lindenbergh, A., van Tuijl, A., Francke, C., Bakker, B. M., & Westerhoff, H. V. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509831103 · Cited by 134 · see citing works

Creation of a Genome-Wide Metabolic Pathway Database for Populus trichocarpa Using a New Approach for Reconstruction and Curation of Metabolic Pathways for Plants

Zhang, P., Dreher, K. A., Karthikeyan, A. S., Chi, A., Pujar, A., Caspi, R., Karp, P. D., Kirkup, V. M., Latendresse, M., Lee, C. K., et al. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.157396 · Cited by 129 · see citing works

Strategies for metabolic flux analysis in plants using isotope labelling

Roscher, A., Kruger, N. J., & Ratcliffe, R. G. (2000) · Journal of Biotechnology · doi:10.1016/s0168-1656(99)00209-6 · Cited by 122 · see citing works

Understanding fatty acid synthesis in developing maize embryos using metabolic flux analysis

Alonso, A. P., Dale, V. L., & Shachar‐Hill, Y. (2010) · Metabolic Engineering · doi:10.1016/j.ymben.2010.04.002 · Cited by 121 · see citing works

Reconstruction and analysis of genome-scale metabolic model of a photosynthetic bacterium

Montagud, A., Navarro, E., de Córdoba, P. F., Urchueguía, J. F., & Patil, K. R. (2010) · BMC Systems Biology · doi:10.1186/1752-0509-4-156 · Cited by 121 · see citing works

Metabolic Network Fluxes in Heterotrophic Arabidopsis Cells: Stability of the Flux Distribution under Different Oxygenation Conditions

Williams, T. C. R., Miguet, L., Masakapalli, S. K., Kruger, N. J., Sweetlove, L. J., & Ratcliffe, R. G. (2008) · PLANT PHYSIOLOGY · doi:10.1104/pp.108.125195 · Cited by 120 · see citing works

Targets of stress-induced oxidative damage in plant mitochondria and their impact on cell carbon/nitrogen metabolism

Taylor, N. L. (2003) · Journal of Experimental Botany · doi:10.1093/jxb/erh001 · Cited by 119 · see citing works

Heterogeneity of plant mitochondrial responses underpinning respiratory acclimation to the cold in Arabidopsis thaliana leaves

ARMSTRONG, A. F., Logan, D. C., Tobin, A. K., O’Toole, P. J., & Atkin, O. K. (2006) · Plant Cell & Environment · doi:10.1111/j.1365-3040.2005.01475.x · Cited by 116 · see citing works

Parallel determination of enzyme activities and in vivo fluxes in Brassica napus embryos grown on organic or inorganic nitrogen source

Junker, B. H., Lonien, J., Heady, L. E., Rogers, A., & Schwender, J. (2007) · Phytochemistry · doi:10.1016/j.phytochem.2007.03.032 · Cited by 109 · see citing works

Subcellular Flux Analysis of Central Metabolism in a Heterotrophic Arabidopsis Cell Suspension Using Steady-State Stable Isotope Labeling

Masakapalli, S. K., Lay, P. L., Huddleston, J. E., Pollock, N. L., Kruger, N. J., & Ratcliffe, R. G. (2009) · PLANT PHYSIOLOGY · doi:10.1104/pp.109.151316 · Cited by 108 · see citing works

A role for Salmonella fimbriae in intraperitoneal infections

Edwards, R. A., Schifferli, D. M., & Maloy, S. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.3.1258 · Cited by 107 · see citing works

Substrate utilization and respiration in relation to growth and maintenance in higher plants.

de Vries, F. W. T. P. (1974) · Netherlands Journal of Agricultural Science · doi:10.18174/njas.v22i1.17235 · Cited by 102 · see citing works

Metabolic Flux Analysis in Plants: From Intelligent Design to Rational Engineering

Libourel, I. G. L., & Shachar‐Hill, Y. (2008) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.58.032806.103822 · Cited by 100 · see citing works

A transient isotopic labeling methodology for 13C metabolic flux analysis of photoautotrophic microorganisms

Shastri, A. A., & Morgan, J. A. (2007) · Phytochemistry · doi:10.1016/j.phytochem.2007.03.042 · Cited by 95 · see citing works

From genomes to in silico cells via metabolic networks

Borodina, I., & Nielsen, J. (2005) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2005.04.008 · Cited by 94 · see citing works

Metabolic flux maps comparing the effect of temperature on protein and oil biosynthesis in developing soybean cotyledons

Iyer, V. V., Sriram, G., Fulton, D. B., Zhou, R., Westgate, M. E., & Shanks, J. V. (2008) · Plant Cell & Environment · doi:10.1111/j.1365-3040.2008.01781.x · Cited by 94 · see citing works

Integration of metabolic databases for the reconstruction of genome-scale metabolic networks

Radrich, K., Tsuruoka, Y., Dobson, P. D., Gevorgyan, A., Swainston, N., Baart, G. J. E., & Schwartz, J. (2010) · BMC Systems Biology · doi:10.1186/1752-0509-4-114 · Cited by 94 · see citing works

Transcription factors involved in terpenoid indole alkaloid biosynthesis in Catharanthus roseus

Memelink, J., & Gantet, P. (2007) · Phytochemistry Reviews · doi:10.1007/s11101-006-9051-z · Cited by 91 · see citing works

Getting to grips with the plant metabolic network

Sweetlove, L. J., Fell, D. A., & Fernie, A. R. (2007) · Biochemical Journal · doi:10.1042/bj20071115 · Cited by 91 · see citing works

Computation of metabolic fluxes and efficiencies for biological carbon dioxide fixation

Boyle, N. R., & Morgan, J. A. (2011) · Metabolic Engineering · doi:10.1016/j.ymben.2011.01.005 · Cited by 89 · see citing works

Insights into plant metabolic networks from steady-state metabolic flux analysis

Kruger, N. J., & Ratcliffe, R. G. (2009) · Biochimie · doi:10.1016/j.biochi.2009.01.004 · Cited by 88 · see citing works

Computational analysis of storage synthesis in developing Brassica napus L. (oilseed rape) embryos: flux variability analysis in relation to 13C metabolic flux analysis

Hay, J. O., & Schwender, J. (2011) · The Plant Journal · doi:10.1111/j.1365-313x.2011.04611.x · Cited by 83 · see citing works

Metabolic network reconstruction and flux variability analysis of storage synthesis in developing oilseed rape (Brassica napus L.) embryos

Hay, J. O., & Schwender, J. (2011) · The Plant Journal · doi:10.1111/j.1365-313x.2011.04613.x · Cited by 71 · see citing works

Simulating Plant Metabolic Pathways with Enzyme-Kinetic Models

Schallau, K., & Junker, B. H. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.109.149237 · Cited by 70 · see citing works

A model‐based method for investigating bioenergetic processes in autotrophically growing eukaryotic microalgae: Application to the green algae Chlamydomonas reinhardtii

Cogne, G., Rügen, M., Bockmayr, A., Titica, M., Dussap, C., Cornet, J., & Legrand, J. (2011) · Biotechnology Progress · doi:10.1002/btpr.596 · Cited by 64 · see citing works

A model-based analysis of the dynamics of carbon balance at the whole-plant level in Arabidopsis thaliana

Christophe, A., Letort, V., Hummel, I., Cournède, P.-H., Reffye, P. D., & Lecœur, J. (2008) · Functional Plant Biology · doi:10.1071/fp08099 · Cited by 63 · see citing works

An in silico compartmentalized metabolic model of <i>Brassica napus</i> enables the systemic study of regulatory aspects of plant central metabolism

Pilalis, E., Chatziioannou, A., Thomasset, B., & Kolisis, F. (2011) · Biotechnology and Bioengineering · doi:10.1002/bit.23107 · Cited by 62 · see citing works

Estimation of metabolic fluxes, expression levels and metabolite dynamics of a secondary metabolic pathway in potato using label pulse‐feeding experiments combined with kinetic network modelling and simulation

Heinzle, E., Matsuda, F., Miyagawa, H., Wakasa, K., & Nishi­oka, T. (2007) · The Plant Journal · doi:10.1111/j.1365-313x.2007.03037.x · Cited by 48 · see citing works

DREAMS of metabolism

Soh, K. C., & Vassily Hatzimanikatis, A. (2010) · Trends in biotechnology · doi:10.1016/j.tibtech.2010.07.002 · Cited by 47 · see citing works

Combining proteomics of root and shoot mitochondria and transcript analysis to define constitutive and variable components in plant mitochondria

Lee, C. P., Eubel, H., O’Toole, N., & Millar, A. H. (2011) · Phytochemistry · doi:10.1016/j.phytochem.2010.12.004 · Cited by 47 · see citing works

Co‐operation between cytosolic and plastidic oxidative pentose phosphate pathways revealed by 6‐phosphogluconate dehydrogenase‐deficient genotypes of maize

Averill, R. H., Bailey-Serres, J. N., & Kruger, N. J. (1998) · The Plant Journal · doi:10.1046/j.1365-313x.1998.00143.x · Cited by 42 · see citing works

Building and analysing genome-scale metabolic models

Fell, D. A., Poolman, M. G., & Gevorgyan, A. (2010) · Biochemical Society Transactions · doi:10.1042/bst0381197 · Cited by 30 · see citing works

Substrate utilization and respiration in relation to growth and maintenance in higher plants

de Vries, F. W. T. P. (1973) · doi:10.18174/195753 · Cited by 29 · see citing works

Metabolic Organization in Plants: A Challenge for the Metabolic Engineer

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Constraining the metabolic genotype–phenotype relationship using a phylogeny of in silico methods

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