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Emotion Regulation in Current and Remitted Depression: A Systematic Review and Meta-Analysis
Open accessAbstract
Background Major Depressive Disorder (MDD) is a highly prevalent, recurrent and potentially chronic disorder. Identifying risk factors and underlying mechanisms to inform preventive and therapeutic interventions is therefore imperative. Emotion regulation is a proposed factor in the development and maintenance of MDD. The aim of the present review was to summarize and synthesize research on self-reported emotion regulation strategy use and emotion regulation abilities in adults diagnosed with current and remitted MDD. Methods Seventy-two eligible studies were retrieved from databases through a systematic literature search. Group differences between individuals with current MDD, remitted MDD and healthy controls were calculated using meta-analytic procedures. Meta-regression analyses investigated potential moderator effects on emotion regulation difficulties. Results Results indicated that individuals with current MDD report higher maladaptive emotion regulation strategy use for avoidance (Hedges’ g = 1.3), rumination (g = 2.1) and suppression (g = 1.1) compared to healthy controls. Also, they reported lower adaptive emotion regulation strategy use for acceptance (g =-1.0), problem solving (g = -1.0) and reappraisal (g = -0.7). Individuals with current MDD reported limited general emotion regulation abilities, indicated by higher alexithymia (g =1.45), lower emotional awareness (g =-0.95), emotional clarity (g = -1.50) and emotional tolerance (g =-1.89). Similar results were found in individuals with remitted MDD for avoidance (g = 1.0), rumination (g = 1.1), suppression (g = 0.6) and general emotion regulation abilities. However, no difference was found between individuals with remitted MDD and healthy controls for adaptive emotion regulation strategies. Meta-regression analyses suggest that age of illness onset, comorbid anxiety and duration of remission influence emotion regulation. Conclusion The present review and meta-analysis indicates that individuals with current and remitted MDD have difficulties with emotion regulation compared to individuals who have never been depressed. Although depressive symptoms improve, emotion regulation difficulties may continue, and could be a contributing factor to relapse. Our findings inform future research on emotion regulation and psychotherapeutic interventions.
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“Difficulties in emotion regulation strategy use play a central role in the development, maintenance, and treatment of depression and anxiety disorders [27–29].”
From Emotion Regulation as a Mechanism of Mindfulness in Individual Cognitive-Behavioral Therapy for Depression and Anxiety Disorders (2024) · cites this paper as [29]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
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“The first pathway to mitigating anxiety and depression symptoms involves reducing perseverative and avoidant emotion regulation strategies, such as rumination, avoidance, and suppression, which are known to maintain and exacerbate internalizing psychopathology [29, 58–62].”
From Emotion Regulation as a Mechanism of Mindfulness in Individual Cognitive-Behavioral Therapy for Depression and Anxiety Disorders (2024) · cites this paper as [29]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“The first pathway to mitigating anxiety and depression symptoms involves reducing perseverative and avoidant emotion regulation strategies, such as rumination, avoidance, and suppression, which are known to maintain and exacerbate internalizing psychopathology [29, 58–62].”
From Emotion Regulation as a Mechanism of Mindfulness in Individual Cognitive-Behavioral Therapy for Depression and Anxiety Disorders (2024) · cites this paper as [29]
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“…levels of depression, however, make it more difficult to differentiate reflection and brooding from each other (Whitmer & Gotlib, 2013), which may be due to depression’s interference with the problem-solving nature of reflection (Bishop & Gagne, 2018; Lawlor et al., 2020; Visted et al., 2018).”
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Emotion Regulation: a Psychophysiological Review
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FAKTOR-FAKTOR RISIKO DEPRESI PADA IBU PASCABERSALIN
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“Beyond affect itself, engagement in dysregulated cognitive strategies such as perseverative cognition, which includes worry and rumination, remains elevated in the remitted state of depression (Stange et al., 2017a; Visted et al., 2018).”
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Krzikalla, C., Buhlmann, U., Andor, T., & Nexhmedin Morina, B. (2024) · Cognitive Therapy and Research · doi:10.1007/s10608-024-10545-2 · Cited by 1
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“A comprehensive meta-analysis of 72 studies found that individuals with major depressive disorder often exhibit reduced general emotion regulation abilities and are more likely to rely on maladaptive strategies such as avoidance, rumination and suppression (Visted et al., 2018).”
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“These results align with Visted et al.’s (2018) systematic review and meta-analysis, which concluded that despite improvements in reported emotional symptoms, difficulties in emotion regulation persisted, posing a risk for future relapses, suggesting a complex relationship between emotion…”
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“However, research has also shown that the interaction of reappraisal and chronic disease had statistically insignificant effect sizes (Visted et al., 2018).”
Liu, X., Zhou, A., Jin, Z., Han, Z. R., Qian, J., & Wang, H. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1447040 · Cited by 1
Steil, R., Preiss, H., Rueger, M. S., Ehring, T. W., Nexhmedin Morina, B., Kuck, S., Mewes, R., Giesebrecht, J., Johow, J., Weise, C., et al. (2025) · European Journal of Psychotraumatology · doi:10.1080/20008066.2025.2538264 · Cited by 1
“A systematic meta-analysis has found limited emotion regulation abilities in patients with depression (Visted et al., 2018).”
Implementing a Trauma-Informed Intervention in a County Jail: Feasibility Study of STAIR
Renn, T., Herod, L., Tripodi, S. J., & Bedard, L. E. (2025) · Research on Social Work Practice · doi:10.1177/10497315251367332 · Cited by 1
“Inability to regulate emotions further exacerbates the challenges faced by incarcerated individuals with mental health challenges, such as depression or anxiety (Visted et al., 2018).”
Miskowiak, K. W., Kjærstad, H. L., Lystlund, S., Sankar, A., Kessing, L. V., & Vinberg, M. (2025) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.70025 · Cited by 1
“Indeed, avoidance is considered a maladaptive emotion regulation strategy associated with poor long-term mental B D t y p e II , n health and depressive symptoms [19].”
Bayraktarlı, E., & Kılıç, N. (2022) · Nesne Psikoloji Dergisi · doi:10.7816/nesne-10-25-08 · Cited by 4
Binge Eating Disorder and Major Depressive Disorder
Fu, K. (2021) · Advances in Social Science, Education and Humanities Research/Advances in social science, education and humanities research · doi:10.2991/assehr.k.210617.060
Köhler, S., Weilnhammer, V. A., Walter, H., Erk, S., Sterzer, P., & Guhn, A. (2021) · Neuropsychobiology · doi:10.1159/000518996
Saveliev, I., & Shahar, N. (2022) · PsyArXiv (OSF Preprints) · doi:10.31234/osf.io/ctp6y
Interventions for major depressive disorder: the role of automatic emotion regulation
Qu, J., Campanella, S., & Yuan, J. (2023) · Stress and Brain · doi:10.26599/sab.2022.9060030
Rahmatullah, B. (2022) · COMSERVA Jurnal Penelitian dan Pengabdian Masyarakat · doi:10.59141/comserva.v2i08.463
Barooti, M., Chinaveh, M., & Saedi, S. (2024) · doi:10.61838/kman.jayps.5.3.5
Hassan, S. S., & Saber, E. H. (2024) · Tanta Scientific Nursing Journal · doi:10.21608/tsnj.2024.346129
Michel, C. A., Schmidt, M. F., Mann, J. J., Herzog, S., Ochsner, K. N., Davachi, L., & Schneck, N. (2024) · Research Square · doi:10.21203/rs.3.rs-4298308/v1
Egli, S., Badenbach, T., van Emmerik, A., Stefan, A. M., & Kopf‐Beck, J. (2024) · doi:10.31219/osf.io/67vhn
Nagel, L. C., Cavallini, A. Q., Tesky, V. A., Schall, A., Katerinis, K. C., Meidinger, C., Arens, E. A., & Stangier, U. (2024) · Geriatric Nursing · doi:10.1016/j.gerinurse.2024.07.014 · Cited by 1
Rumination as a Transdiagnostic Risk Factor to Psychopathology
Kovács, L. N. (2023) · Eötvös Loránd Tudományegyetem · doi:10.15476/elte.2022.072
Sumalrot, T., Ngamseesan, J., & Pattanaseri, K. (2024) · Siriraj Medical Journal/San Sirirat · doi:10.33192/smj.v76i9.269285
McLeish, A. C., Hartson, K. R., Hart, J. L., & Walker, K. L. (2024) · Psychology and Psychotherapy Theory Research and Practice · doi:10.1111/papt.12560 · Cited by 1
Hannoon, N., El-Khodary, B., & Zhang, Z. (2024) · European Journal of Psychotraumatology · doi:10.1080/20008066.2024.2433834
Other Psychiatric Comorbidities and Borderline Personality Disorder
Salavati, M., & Selby, E. A. (2024) · Springer eBooks · doi:10.1007/978-3-031-75503-3_16
Priego-Ojeda, M., Ursu, A., Blanch, À., & Guiu, G. F. (2025) · Journal of Personality Assessment · doi:10.1080/00223891.2025.2496258 · Cited by 1
“The relationship between emotion regulation strategies and psychopathology have been explored and supported by past research (Aldao et al., 2010; Everaert & Joormann, 2019; Garnefski & Kraaij, 2006b; Gross & Jazaieri, 2014; Liu & Thompson, 2017; Visted et al., 2018).”
Gruffy, A., Moka, A., & Daches, S. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.119539
Understanding depression and emotion regulation in jobseekers: an expectancy-value perspective
Torre, J. M., Pavani, J., & Dauvier, B. (2025) · Personality and Individual Differences · doi:10.1016/j.paid.2025.113359
Seidman, A. J., George, C. J., & Kovács, M. (2025) · Clinical Psychological Science · doi:10.1177/21677026251338752
Tan, M., Rizvi, S. J., Hurt-Thaut, C., & Thaut, M. H. (2025) · PLOS mental health. · doi:10.1371/journal.pmen.0000361
“This aligns with findings that individuals with depression have a diminished hedonic capacity, suggesting a persistent deficit in experiencing pleasure [28,29].”
Knorr, A. C., Wallace, G. T., Schatten, H. T., Prince, M. A., Boudreaux, E. D., Miller, I. W., Camargo, C. A., Conner, B. T., & Arias, S. A. (2025) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2025.10.007
“Research underscores the role of emotion dysregulation in depression (Joormann and Stanton, 2016; Visted et al., 2018), NSSI (Knorr et al., 2019; Wolff et al., 2019; Zielinski et al., 2018), and suicide risk (Rogante et al., 2024; Turton et al., 2021).”
Köten, E. (2025) · Kafkas Üniversitesi Sosyal Bilimler Enstitüsü Dergisi · doi:10.56597/kausbed.1717162
Broeder, C., Pasteuning, J., Broeders, T. A. A., Linsen, F., Schoonheim, M. M., Sep, M. S. C., & Vinkers, C. H. (2026) · Neurobiology of Stress · doi:10.1016/j.ynstr.2026.100817
“…functional disturbances in emotion regulation and cognitive processing (Dotson et al., 2020; Gruhn et al., 2020; Masson et al., 2016; Nagy et al., 2021; Visted et al., 2018; Wang et al., 2024), which can both be disrupted under stress (Langer et al., 2025; Shields et al., 2016; Wessa et al., 2024).”
Sanwald, S., Widenhorn‐Müller, K., Montag, C., & Kiefer, M. (2022) · Figshare · doi:10.6084/m9.figshare.19144947
Schmitz, M., Back, S. N., Seitz, K. I., Harbrecht, N. K., Streckert, L., Schulz, A., Herpertz, S. C., & Bertsch, K. (2024) · Figshare · doi:10.6084/m9.figshare.26568196
Wisting, L., Johnson, S. U., Bulik, C. M., Andreassen, O. A., Rø, Ø., & Bang, L. (2021) · Figshare · doi:10.6084/m9.figshare.13524867
Self-regulatory contributions to depressive symptoms in a community sample of youth
Abraham, E. H., & McAuley, T. (2025) · Personalized Medicine in Psychiatry · doi:10.1016/j.pmip.2025.100163
Hu, Y., Yang, Y., He, Z., Wang, D., Xu, F., Zhu, X., & Wang, K. (2024) · Figshare · doi:10.6084/m9.figshare.25485830
Bırni, G., & Eryılmaz, A. (2025) · European Journal of Psychology and Educational Research · doi:10.12973/ejper.8.4.277
Metadata
- Authors
- Visted, E., Vøllestad, J., Nielsen, M. B., & Schanche, E.
- Affiliations
- Haukeland University Hospital (NO)
- University of Bergen (NO)
- National Institute of Occupational Health (NO)
- Corresponding author
- Visted, Endre
- Venue
- Frontiers in Psychology
- Publisher
- Frontiers Media SA
- Published
- 2018-05-18
- Volume
- 9
- Pages
- 756-756
- ISSN
- 1664-1078 (ISSN-L)
- PMC
- PMC5968125
- OpenAlex
- W2800418807
- Cited by
- 337
- References
- 122
- Citations by year
- 2026: 54 · 2025: 48 · 2024: 61 · 2023: 42 · 2022: 38 · 2021: 31 · 2020: 25 · 2019: 32 · 2018: 6
- FWCI
- 3.74
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Frontiers in Psychology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- NORA - Norwegian Open Research Archives (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- NORA - Norwegian Open Research Archives (submittedVersion, other-oa)
- Funders
- L. Meltzers Høyskolefond (7183, 16545)
- Universitetet i Bergen
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- emotion regulation, major depressive disorder, remitted depression, maladaptive emotion regulation, rumination, avoidance, emotional suppression, cognitive reappraisal, acceptance, alexithymia, emotional awareness, emotional clarity, emotional tolerance, relapse risk, anxiety comorbidity, remission duration
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