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Cognitive Control and Flexibility in the Context of Stress and Depressive Symptoms: The Cognitive Control and Flexibility Questionnaire
Open accessAbstract
Cognitive control and (cognitive) flexibility play an important role in the ability to adapt to continuously changing environments. In addition to facilitating goal-directed behaviors, cognitive control and flexibility have been implicated in emotion regulation, and disturbances of these abilities were observed in mood and anxiety disorders. The reported studies examined the processes related to cognitive control and flexibility, emotional regulation and depressive symptoms, within the context of stressful experiences. To this end, a brief (18-item) self-report measure - the Cognitive Control and Flexibility Questionnaire (CCFQ) - was developed. This questionnaire measures the extent to which an individual is capable of exerting control over intrusive, unwanted (negative) thoughts and emotions in order to flexibly adapt and cope with a stressful situation. In Study 1, the CCFQ was assessed among both university students (N = 300) and a community sample (N = 302). Preliminary analyses suggested a stable and reliable two-factor structure, that of cognitive control over emotion, and appraisal and coping flexibility. Scores on the CCFQ were strongly associated with greater depressive symptoms, even after controlling for other measures that had been taken to reflect cognitive control and (in)flexibility (e.g., the Ruminative Response Scale; Perseverative Thinking Questionnaire). In Study 2 (N = 368), lower scores on the CCFQ were related to more negative stressor appraisals (i.e., greater perceived threat and uncontrollability) of a personally meaningful stressful event. Perceptions of threat and uncontrollability, in turn, partially accounted for the association between CCFQ subscale scores and depressive symptoms. The relation between lower CCFQ scores and heightened depressive symptoms was also partially accounted for by less frequent engagement in problem-focused coping and more use of emotion-focused methods. In Study 3 (N = 47 females), lower scores on the cognitive control over emotion component of the CCFQ predicted elevated negative affect and an exacerbated cortisol response following an acute psychosocial stressor (Trier Social Stress Test). The present research points to the CCFQ as a useful self-report tool to identify ways through which cognitive control and flexibility might be manifested in stressful situations, and how reductions in flexibility might be accompanied by elevated symptoms of depression.
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“as several studies have found CI to be associated with self and parent-reported depression in autistic individuals (Gabrys et al., 2018; Hollocks et al., 2014, 2022a, 2022b; Lawson et al., 2015).”
From Investigating the Effects of Transdiagnostic Processes on Anxiety and Depression Symptoms in Autistic Young People: the Mediating Role of Emotion Dysregulation. (2025) · cites this paper as Gabrys et al., 2018
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“CI has been linked to flexible problem solving and transition between activities in autistic individuals (Uddin, 2021) and associated with anxiety and depression in autistic youth (Hollocks et al., 2019) and adult general population samples (Gabrys et al., 2018; Wang et al., 2019).”
From Investigating the Effects of Transdiagnostic Processes on Anxiety and Depression Symptoms in Autistic Young People: the Mediating Role of Emotion Dysregulation. (2025) · cites this paper as Gabrys et al., 2018
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BackgroundJain, T., Shukla, R., & Panwar, N. (2024) · Psychological Reports · doi:10.1177/00332941241268625 · Cited by 10
“In this recent work Gabrys et al. (2018) conceptualized cognitive control as paying attention towards pertinent task as hand, while sieving out the irrelevant ones.”
InfluentialCreating a resilient pedagogy: Character strengths intervention for aspiring educators
Janapati, G., & Vijayalakshmi, V. (2024) · Acta Psychologica · doi:10.1016/j.actpsy.2024.104465 · Cited by 21
KİYE, S., & Habeş, E. Ç. (2024) · İnönü Üniversitesi Eğitim Fakültesi Dergisi · doi:10.17679/inuefd.1481952 · Cited by 10
Kluwe‐Schiavon, B., Zorzi, L. D., Meireles, J., Leite, J., Sequeira, H., & Carvalho, S. (2022) · PLoS ONE · doi:10.1371/journal.pone.0269496 · Cited by 10
Resilience trajectories of cancer survivors: a meaning-making perspective
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Satıcı, B., Tekin, E. G., & Deniz, M. (2020) · Yildiz Technical University - AVESIS · doi:10.17556/erziefd.632776 · Cited by 10
“We expect cognitive flexibility will lead to increased feelings of well-being since it allows individuals to cope with the problems of changing the environment, regulate their emotions and experience more positive emotions (Gabrys et al., 2018; Wilson, Nusbaum, Whitney, Hinson, & 2018).”
InfluentialSometti, D., Ballan, C., Wang, H., Braun, C., & Enck, P. (2021) · Scientific Reports · doi:10.1038/s41598-021-83994-4 · Cited by 11
Reliability and validation of the Turkish adaptation of the mistake rumination scale
Kabadayı, F., & Mercan, O. (2021) · Current Psychology · doi:10.1007/s12144-021-01972-5 · Cited by 9
Ram, D., Mushtaq, N. F., Honnugudi, B. D., & Alammar, M. A. (2022) · Indian Journal of Occupational and Environmental Medicine · doi:10.4103/ijoem.ijoem_213_21 · Cited by 9
Fen, Y., Jia, S., Liu, Q., Guo, Z., Li, S., Wang, X., & Pan, L. (2025) · Brain and Behavior · doi:10.1002/brb3.70285 · Cited by 9
Avcı, M. Z. (2025) · Computers & Education · doi:10.1016/j.compedu.2025.105540 · Cited by 12
Design and Validation of the Adaptation to Change Questionnaire: New Realities in Times of COVID-19
Fuentes, M. D. C. P., Jurado, M. D. M. M., Martínez, Á. M., Fernández‐Martínez, E., Valenzuela, R. F., Herrera‐Peco, I., Jiménez‐Rodríguez, D., Méndez, I., García, A. S., Márquez, M. D. M. S., et al. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17155612 · Cited by 10
“This capacity in turn depends on the ability to detect characteristics and changes in situations [38].”
BackgroundInfluentialVolpe, V. V., Beacham, A. R., & Olafunmiloye, O. (2019) · Journal of Health Psychology · doi:10.1177/1359105319869812 · Cited by 9
“Such flexibility in the context of racial discrimination would be optimal, as it would allow Black young adults to generate and judge the costs and benefits of a multitude of response options, a cognitive appraisal process (Bonanno and Burton, 2013; Gabrys et al., 2018; Outlaw, 1993).”
BackgroundThe Role of Executive Function in Children’s Mindfulness Experience
Butterfield, K. M., & Roberts, K. P. (2021) · Mindfulness · doi:10.1007/s12671-021-01802-6 · Cited by 17
“Researchers have proposed a relationship between flexible thinking and depressive symptoms, such that greater cognitive flexibility may be associated with the “endorsement of more effective coping strategies” (Gabrys et al., 2018).”
BackgroundLiu, C., Chen, H., Xu, W., Dai, S., & Lin, S. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1422845 · Cited by 9
“…the mediating effect of cognitive flexibility between H-SCE and depression symptom among urban vocational college students, (C) the mediating effect of cognitive flexibility between H-SCE and depression symptom among rural vocational college students. and depressive symptom (Gabrys et al., 2018).”
Junker, N. M., Heimrich, J., Häusser, J. A., & Rigotti, T. (2025) · Work & Stress · doi:10.1080/02678373.2025.2553651 · Cited by 9
“…on days when individuals constructively ponder about work problems more than usual, they should be more likely to see how their reflections are relevant (have the necessary cognitive flexibility; Gabrys et al., 2018) and can apply those to the family role, thus improving WFE in the evening.”
Xu, A. J., Sun, H., & Ma, J. (2026) · Human Resource Management · doi:10.1002/hrm.70050 · Cited by 9
Marchiol, F., Lionetti, F., Luxardi, G. L., Cavallero, C., Roberts, M., & Penolazzi, B. (2020) · European Eating Disorders Review · doi:10.1002/erv.2781 · Cited by 8
Ill-being or well-being? Energising international business travellers
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“…is often present in IBTs) is thought to slow down cognitive flexibility, (Jiang and Rau, 2017) meaning they may struggle to adapt to new situations (that travel typically presents), lose perceived control over their abilities and be prone to negative thoughts and emotions (Gabrys et al., 2018).”
BackgroundMa, R., Zhang, Q., Zhang, C., & Xu, W. (2024) · BMC Psychology · doi:10.1186/s40359-024-01908-1 · Cited by 7
“Cognitive flexibility is a key component of executive functioning, lack of which has been suggested and initially proved as a risk factor for psychological distress including depression and anxiety [27, 48–51].”
BackgroundBavali‐Gazik, A., Vagharseyyedin, S. A., Saremi, Z., & Shafiee, F. (2024) · Musculoskeletal Care · doi:10.1002/msc.1923 · Cited by 7
EEG entropy modulation as a biomarker of emotion regulation and resilience
Creel, W. T., & Hartman, R. E. (2025) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2025.10.013 · Cited by 8
“Cognitive flexibility, the ability to adapt one ’ s thinking in response to new or unexpected events, is a fundamental component of healthy psychological functioning (Gabrys et al., 2018).”
Reframing oxytocin as a behavioral flexibility hormone
Walle, K. M., Sartorius, A. M., Deilhaug, E., Kang, H., Nærland, T., Andreassen, O. A., Westlye, L. T., & Quintana, D. S. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106628 · Cited by 10
Genç, A. B. (2024) · Türk Psikolojik Danışma ve Rehberlik Dergisi · doi:10.17066/tpdrd.1311383_7 · Cited by 7
Demirtaş, A. S. (2021) · Dusunen Adam The Journal of Psychiatry and Neurological Sciences · doi:10.14744/dajpns.2020.00124 · Cited by 11
“(28) to evaluate the perceived ability of a person to exercise control over Table 1: Sociodemographic characteristics of the participants (n=674)”
BackgroundInfluentialÇutuk, Z. A. (2021) · Journal of Educational Sciences & Psychology · doi:10.51865/jesp.2021.2.17 · Cited by 7
Özen, F., & ÜÇÜNCÜ, A. S. (2022) · International Journal of Psychology and Educational Studies · doi:10.52380/ijpes.2022.9.2.752 · Cited by 10
Metadata
- Authors
- Gabrys, R. L., Tabri, N., Anisman, H., & Matheson, K.
- Affiliations
- Carleton University (CA)
- Royal Ottawa Mental Health Centre (CA)
- Corresponding author
- Gabrys, Robert L.
- Venue
- Frontiers in Psychology
- Publisher
- Frontiers Media SA
- Published
- 2018-11-19
- Volume
- 9
- Pages
- 2219-2219
- ISSN
- 1664-1078 (ISSN-L)
- PMC
- PMC6252356
- OpenAlex
- W2901368915
- Cited by
- 281
- References
- 97
- Citations by year
- 2026: 43 · 2025: 52 · 2024: 49 · 2023: 30 · 2022: 43 · 2021: 38 · 2020: 19 · 2019: 7
- FWCI
- 20.96
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Frontiers in Psychology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Carleton University's Institutional Repository (MacOdrum Library, Carleton University) (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Natural Sciences and Engineering Research Council of Canada (9180)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Keywords
- cognitive control, cognitive flexibility, depressive symptoms, stress, emotion regulation, coping flexibility, stress appraisal, threat perception, problem-focused coping, emotion-focused coping, rumination, perseverative thinking, cortisol response, negative affect, Trier Social Stress Test, self-report measure development
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