The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.
Effect of Inflammation on the Process of Stroke Rehabilitation and Poststroke Depression
Abstract
A considerable body of evidence has shown that inflammation plays an important role in the process of stroke rehabilitation and development of poststroke depression (PSD). However, the specific molecular and cellular mechanisms involved remain unclear. In this review, we summarize how neuroinflammation affects stroke rehabilitation and PSD. We mainly focus on the immune/inflammatory response, involving astrocytes, microglia, monocyte-derived macrophages, cytokines (tumor necrosis factor alpha, interleukin 1), and microRNAs (microRNA-124, microRNA 133b). This review provides new insights into the effect of inflammation on the process of stroke rehabilitation and PSD and potentially offer new therapeutic targets of stroke and PSD.
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“Evidence from previous studies has shown that the expression of miR-124 correlated inversely with the activation state of microglia [14, 15, 48]”
From CX3CL1/CX3CR1 axis attenuates early brain injury via promoting the delivery of exosomal microRNA-124 from neuron to microglia after subarachnoid hemorrhage (2020) · cites this paper as [14]
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“It has been reported that miR-124 participates in regulating microglial activation [14–16].”
From CX3CL1/CX3CR1 axis attenuates early brain injury via promoting the delivery of exosomal microRNA-124 from neuron to microglia after subarachnoid hemorrhage (2020) · cites this paper as [14]
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Citations
Cites
Modulators of microglial activation and polarization after intracerebral haemorrhage
Lan, X., Han, X., Li, Q., Yang, Q.-W., & Wang, J. (2017) · Nature Reviews Neurology · doi:10.1038/nrneurol.2017.69 · Cited by 915
The dual role of astrocyte activation and reactive gliosis
Pekny, M., Wilhelmsson, U., & Pekna, M. (2014) · Neuroscience Letters · doi:10.1016/j.neulet.2013.12.071 · Cited by 670
The biphasic function of microglia in ischemic stroke
Ma, Y., Wang, J., Wang, Y., & Yang, G.-Y. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.01.005 · Cited by 655
Post-stroke depression: Mechanisms and pharmacological treatment
Villa, R. F., Ferrari, F., & Moretti, A. (2018) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2017.11.005 · Cited by 532
NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes
Freeman, L., Guo, H., David, C. N., Brickey, W. J., Jha, S., & Ting, J. P.-Y. (2017) · Journal of Experimental Medicine · doi:10.1084/jem.20150237 · Cited by 397
Wattananit, S., Tornero, D., Graubardt, N., Memanishvili, T., Monni, E., Tatarishvili, J., Miskinyte, G., Ge, R., Ahlenius, H., Lindvall, O., et al. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.4317-15.2016 · Cited by 353
Depletion of microglia exacerbates postischemic inflammation and brain injury
Jin, W.-N., Shi, S. X.-Y., Li, Z., Li, M., Wood, K., Gonzales, R. J., & Liu, Q. (2017) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x17694185 · Cited by 351 · cited 2×
“Activated microglia also contribute to resolving the inflammatory response by producing IL-10 and TGFβ and inhibiting the ischemia-induced astrocytic response as a neuroprotective effect during stroke rehabilitation (21, 28, 29).”
BackgroundMicroglia–blood vessel interactions: a double-edged sword in brain pathologies
Dudvarski Stankovic, N., Teodorczyk, M., Ploen, R., Zipp, F., & Schmidt, M. H. H. (2016) · Acta Neuropathologica · doi:10.1007/s00401-015-1524-y · Cited by 301
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Xin, H., Wang, F., Li, Y., Lu, Q.-E., Cheung, W. L., Zhang, Y., Zhang, Z. G., & Chopp, M. (2017) · Cell Transplantation · doi:10.3727/096368916x693031 · Cited by 267
Cited by
Post-stroke depression: A 2020 updated review
Medeiros, G. C., Roy, D., Kontos, N., & Beach, S. R. (2020) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2020.06.011 · Cited by 587
Cordaro, M., Cuzzocrea, S., & Crupi, R. (2020) · Antioxidants · doi:10.3390/antiox9030216 · Cited by 98
Chen, X., Jiang, M., Li, H., Wang, Y., Shen, H., Li, X., Zhang, Y., Wu, J., Yu, Z., & Chen, G. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-020-01882-6 · Cited by 85
Elevated monocyte-to-HDL cholesterol ratio predicts post-stroke depression
Li, Y., Zhang, M., Xue, M., Liu, D., & Sun, J. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.902022 · Cited by 27
Metadata
- Authors
- Fang, M., Zhong, L., Jin, X., Cui, R., Yang, W., Gao, S., Lv, J., Li, B., & Liu, T.
- Venue
- Frontiers in Psychiatry
- Publisher
- Frontiers Media SA
- Published
- 2019-04-11
- Volume
- 10
- ISSN
- 1664-0640
- PMC
- PMC6470379
- Cited by
- 66
- References
- 72
- Funders
- Jilin University (2015212)
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- Fang, M., Zhong, L., Jin, X., Cui, R., Yang, W., Gao, S., Lv, J., Li, B., & Liu, T. (2019). Effect of Inflammation on the Process of Stroke Rehabilitation and Poststroke Depression. Frontiers in Psychiatry. https://doi.org/10.3389/fpsyt.2019.00184
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