Alexithymia and Treatment Outcome in Anorexia Nervosa: A Scoping Review of the Literature
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Alexithymia is of great interest as an outcome predictor of recovery from anorexia nervosa, since it may interfere with both treatment compliance and patients' ability to benefit from the adopted interventions. For this reason, in the last years new treatment approaches targeting emotion identification, expression, and regulation have been applied and tested. Using the PRISMA methodology, we performed a scoping review of the literature about treatment outcome in anorexia nervosa, in terms of changes in alexithymia as assessed by its most commonly used self-report measure, the Toronto Alexithymia Scale (TAS). The Medline and Scopus databases were searched, and articles were included if matching the following criteria: dealing with patients affected by anorexia nervosa, without limits of age; involving the application of any kind of targeted therapy or treatment; assessing alexithymia and the effect of a treatment intervention on alexithymia, using the TAS. Ten studies were eventually included; overall, according to the selected studies, alexithymia levels often remain high even after specific treatment. Further research aimed at a deeper understanding of the actual impact of alexithymia on the outcome of anorexia, as well as exploring alternative treatment strategies for alexithymia in eating disorders (EDs), are warranted.
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Many people with AN experience alexithymia and suppress emotions as an emotional coping strategy.
“Many of us with AN experience alexithymia [93, 94] and suppress our emotions as an emotional coping strategy [22, 95].”
From A lived experience response to the proposed diagnosis of terminal anorexia nervosa: learning from iatrogenic harm, ambivalence and enduring hope (2023) · cites this paper as [94]
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Renzi, A., Cerroni, S., Marini, I., Trani, M. D., Pasquini, M., & Mariani, R. (2026) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2026.07.020
- Authors
- Gramaglia, C., Gambaro, E., & Zeppegno, P.
- Affiliations
- Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT)
- Corresponding author
- Zeppegno, Patrizia
- Venue
- Frontiers in Psychiatry
- Publisher
- Frontiers Media SA
- Published
- 2020-02-14
- Volume
- 10
- Pages
- 991-991
- ISSN
- 1664-0640 (ISSN-L)
- PMC
- PMC7033613
- OpenAlex
- W3006305683
- Cited by
- 32
- References
- 67
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 5 · 2023: 9 · 2022: 4 · 2021: 3 · 2020: 2
- FWCI
- 0.35
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Frontiers in Psychiatry (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- alexithymia, anorexia nervosa, treatment outcomes, Toronto Alexithymia Scale, emotional awareness, emotion regulation, eating disorders, medication adherence, recovery
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