Cited by 261Digital Mental Health InterventionsMental Health Research TopicsEmotion and Mood Recognition

The DOI matches its Crossref record; 85 of the 85 references it cites were found in a registry or an index; 4 of the 30 sources its claims cite were checked for support.

Predicting Symptoms of Depression and Anxiety Using Smartphone and Wearable Data

Open access
Moshe, Isaac, Terhorst, Yannik, Opoku Asare, Kennedy, Sander, Lasse Bosse, Ferreira, Denzil, Baumeister, Harald, Mohr, David C., Pulkki-Råback, Laura·2021·Frontiers in Psychiatry

Abstract

Background: Depression and anxiety are leading causes of disability worldwide but often remain undetected and untreated. Smartphone and wearable devices may offer a unique source of data to detect moment by moment changes in risk factors associated with mental disorders that overcome many of the limitations of traditional screening methods. Objective: The current study aimed to explore the extent to which data from smartphone and wearable devices could predict symptoms of depression and anxiety. Methods: A total of N = 60 adults (ages 24–68) who owned an Apple iPhone and Oura Ring were recruited online over a 2-week period. At the beginning of the study, participants installed the Delphi data acquisition app on their smartphone. The app continuously monitored participants' location (using GPS) and smartphone usage behavior (total usage time and frequency of use). The Oura Ring provided measures related to activity (step count and metabolic equivalent for task), sleep (total sleep time, sleep onset latency, wake after sleep onset and time in bed) and heart rate variability (HRV). In addition, participants were prompted to report their daily mood (valence and arousal). Participants completed self-reported assessments of depression, anxiety and stress (DASS-21) at baseline, midpoint and the end of the study. Results: Multilevel models demonstrated a significant negative association between the variability of locations visited and symptoms of depression (beta = −0.21, p = 0.037) and significant positive associations between total sleep time and depression (beta = 0.24, p = 0.023), time in bed and depression (beta = 0.26, p = 0.020), wake after sleep onset and anxiety (beta = 0.23, p = 0.035) and HRV and anxiety (beta = 0.26, p = 0.035). A combined model of smartphone and wearable features and self-reported mood provided the strongest prediction of depression. Conclusion: The current findings demonstrate that wearable devices may provide valuable sources of data in predicting symptoms of depression and anxiety, most notably data related to common measures of sleep.

Overview

AI snapshot

Written from the paper’s full text.

TL;DR

In a 30-day observational study of 55 adults using an iPhone and Oura Ring during COVID-19 restrictions, smartphone GPS and wearable sleep/HRV data predicted depression and anxiety symptoms in multilevel models. A combined model of passive sensing plus daily self-reported mood best predicted depression, while EMA-only models were strongest for anxiety and stress.

Key findings

  • Location variance was negatively associated with depression (beta = −0.21, p = 0.037); no other GPS features were significantly associated with depression, anxiety, or stress.
  • Wearable sleep/HRV measures predicted symptoms: total sleep time (beta = 0.24, p = 0.023) and time in bed (beta = 0.26, p = 0.020) were positively associated with depression; wake after sleep onset (beta = 0.23, p = 0.035) and HRV (beta = 0.26, p = 0.035) were positively associated with anxiety.
  • EMA valence was related to depression (beta = −0.39, p = 0.001), anxiety (beta = −0.30, p = 0.014), and stress (beta = −0.39, p < 0.001); the combined EMA plus digital phenotyping model had the strongest prediction of depression, while EMA-only models were strongest for anxiety and stress.
  • Baseline DASS-21 scores were depression M = 3.78, SD = 3.48; anxiety M = 2.73, SD = 2.68; stress M = 6.00, SD = 3.82, with 67.3% normal depression, 70.9% normal anxiety, and 65.5% normal stress.

Methods

  • Longitudinal observational study with repeated measurements over 30 days; N = 60 recruited online (55 in final analysis), ages 24–68, mean age 42.8 (SD 11.6), required to own an iPhone and Oura Ring.
  • Data sources: Delphi smartphone app continuously monitored GPS and smartphone usage; Oura Ring measured activity (steps, MET), sleep (TST, SOL, WASO, TIB), and HRV; EMA mood was prompted 3 times daily (valence and arousal); DASS-21 was completed at baseline, day 16, and day 31.
  • Analysis: Spearman correlations with cluster-wise Bonferroni-Holm adjustment; multilevel models with random intercepts and slopes, z-standardized predictors, multiple imputation (20 datasets, 15 iterations), and likelihood ratio tests for combined models.

Limitations

  • Stated: observational design cannot establish causality or direction; pooling data prevented examining high-frequency processes and temporal precedence; small sample likely underpowered for small effects; sample was skewed toward white, employed, educated, iOS-using, non-clinical participants; no pre-pandemic movement data were available to confirm restricted movement.
  • Stated: missingness occurred in DASS-21 (10%) and sensing variables (9.1%), assumed missing at random and handled with multiple imputation.
  • Evident: the results text states no significant relationship between arousal and depression, anxiety, or stress, but tables report arousal in the combined depression model and the EMA stress model, indicating inconsistent reporting.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.3389/fpsyt.2021.625247

Cites

85 of 85 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

27 Own result · 19 Not checked yet · 16 Own method · 6 Own interpretation · 2 No basis given · 1 Supported · 1 Partly supported · accuracy not yet measured

Verify all 26 references — free account

Show all 46 claims

  • Probably not a substantial claim. 18
  • It may state two separate claims as one. 11
26 of 26
  • The authors state this as an assumption.

    Missingness in the DASS-21 assessment and sensing variables was missing at random (MAR), meaning missingness depended on observed data.

    “Missingness only occurred in the DASS-21 assessment (10%) and the sensing variables (9.1%) and was assumed to be missing at random (MAR), meaning missingness depended on observed data (51, 52).”
  • The paper relies on this without support.

    Participants' movement was indeed more limited during the study period than before the pandemic.

    “we were unable to provide any data comparing participants' movement before and during the study to confirm that their movement was indeed more limited during the study period.”
2 of 2

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Statistics recomputed

Every reported test result, recomputed from its test statistic and degrees of freedom. A result shows as not adding up only once an independent check has confirmed it.

  • Consistentt(81) = -2.13reported p = .037 · recomputed p = .036

    “t(81) = −2.13, p = .037”

  • Consistentt(73) = 2.33reported p = .023 · recomputed p = .023

    “t(73) = 2.33, p = .023”

  • Consistentt(59) = 2.39reported p = .02 · recomputed p = .020

    “t(59) = 2.39, p = .020”

  • Consistentt(90) = 2.13reported p = .035 · recomputed p = .036

    “t(90) = 2.13, p = .035”

  • Consistentt(71) = 2.15reported p = .035 · recomputed p = .035

    “t(71) = 2.15, p = .035”

  • Consistentt(55) = -3.43reported p = .001 · recomputed p = .001

    “t(55) = −3.43, p = .001”

  • Consistentt(57) = -2.54reported p = .014 · recomputed p = .014

    “t(57) = −2.54, p = .014”

  • Consistentt(74) = -3.64reported p < .001 · recomputed p < .001

    “t(74) = −3.64, p < .001”

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Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

Each contradiction between two passages listed here was confirmed by an independent check.

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Citations

Cites

Show all 83 references

Research works printed but not linked: 2

  1. Holm, 1979, Board of the foundation of the scandinavian journal of statistics a simple sequentially rejective multiple test procedure a simple sequentially rejective multiple test procedure, Source Scand J Stat Scand J Stat., 6, 65
  2. Cummins, 2019, Mobile sensing and digital phenotyping in psychoinformatics

Cited by

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Metadata

Authors
Moshe, I., Terhorst, Y., Opoku Asare, K., Sander, L. B., Ferreira, D., Baumeister, H., Mohr, D. C., & Pulkki-Råback, L.
Affiliations
  • University of Helsinki (FI)
  • Universität Ulm (DE)
  • University of Freiburg (DE)
  • University of Oulu (FI)
  • Northwestern University (US)
Corresponding author
Moshe, Isaac
Venue
Frontiers in Psychiatry
Published
2021-01-28
Volume
12
Pages
625247-625247
ISSN
1664-0640 (ISSN-L)
OpenAlex
W3126710441
Cited by
261
References
83
Citations by year
2026: 45 · 2025: 50 · 2024: 50 · 2023: 50 · 2022: 47 · 2021: 19
FWCI
36.64
Type
journal article
Language
en
Open access
Locations
  • Frontiers in Psychiatry (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Työväentutkimus Vuosikirja (submittedVersion)
  • OPen Access Repositorium der Universität Ulm (OPARU) (Ulm University) (submittedVersion, other-oa)
  • Universität Ulm, Kommunikations- und Informationszentrum (kiz) (cc-by)
Funders
Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg
Topics
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › Emotion and Mood Recognition
Keywords
depression, anxiety, smartphone data, wearable devices, Oura Ring, heart rate variability, sleep, GPS location data, smartphone usage behavior, mood, mental health screening, stress, DASS-21

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