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Muscarinic Receptor Agonists and Antagonists

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Broadley, Kenneth J., Kelly, David R.·2001·Molecules
DOI 10.3390/60300142
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Abstract

A comprehensive review of pharmacological and medical aspects of the muscarinic class of acetylcholine agonists and antagonists is presented. The therapeutic benefits of achieving receptor subtype selectivity are outlined and applications in the treatment of Alzheimer’s disease are discussed. A selection of chemical routes are described, which illustrate contemporary methodology for the synthesis of chiral medicinal compounds (asymmetric synthesis, chiral pool, enzymes). Routes to bicyclic intrannular amines and intramolecular Diels-Alder reactions are highlighted.

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Metadata

Authors
Broadley, K. J., & Kelly, D. R.
Venue
Molecules
Publisher
MDPI AG
Published
2001-02-28
Volume
6
Issue
3
Pages
142-193
ISSN
1420-3049 (ISSN-L)
DOI
10.3390/60300142
OpenAlex
W1988321640
Cited by
504
References
1
FWCI
19.17
Type
journal article
Language
en
Open access
gold
Licence
creativecommons.org/licenses/by/3.0/ (vor)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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How to cite

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This page
CoChat. (2026). Citation check: Muscarinic Receptor Agonists and Antagonists. https://app.cochat.ai/papers/10.3390/60300142
The paper
Broadley, K. J., & Kelly, D. R. (2001). Muscarinic Receptor Agonists and Antagonists. Molecules. https://doi.org/10.3390/60300142

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.