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A Qualitative and Comprehensive Analysis of Caries Susceptibility for Dental Fluorosis Patients

Li, Qianrui, Shen, Jiaqi, Qin, Tao, Zhou, Ge, Li, Yifeng, Chen, Zhu, Li, Mingyun·2021·Antibiotics
DOI 10.3390/antibiotics10091047PMC PMC8464924
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Abstract

Dental fluorosis (DF) is an endemic disease caused by excessive fluoride exposure during childhood. Previous studies mainly focused on the acid resistance of fluorotic enamel and failed to reach a consensus on the topic of the caries susceptibility of DF patients. In this review, we discuss the role of DF classification in assessing this susceptibility and follow the “four factors theory” in weighing the pros and cons of DF classification in terms of host factor (dental enamel and saliva), food factor, bacteria factor, and DF treatment factor. From our analysis, we find that susceptibility is possibly determined by various factors such as the extent of structural and chemical changes in fluorotic enamel, eating habits, fluoride levels in diets and in the oral cavity, changes in quantity and quality of saliva, and/or oral hygiene. Thus, a universal conclusion regarding caries susceptibility might not exist, instead depending on each individual’s situation.

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Figure 1 Schematic diagram of the de/remineralization process. The process of remineralization will yield fluoride-rich, carbonate-deficient enamel surfaces.
Figure 1 Schematic diagram of the de/remineralization process. The process of remineralization will yield fluoride-rich, carbonate-deficient enamel surfaces.CC BY · PubMed Central
Figure 2 Schematic diagram explaining how mastication influences salivary secretion.
Figure 2 Schematic diagram explaining how mastication influences salivary secretion.CC BY · PubMed Central

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Metadata

Authors
Li, Q., Shen, J., Qin, T., Zhou, G., Li, Y., Chen, Z., & Li, M.
Affiliations
  • State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu 610041, China
  • Key Laboratory of Oral Disease Research, School of Stomatology, Zunyi Medical University, Zunyi 563000, China
ORCID
Venue
Antibiotics
Publisher
MDPI AG
Published
2021-08-27
Volume
10
Issue
9
Pages
1047
ISSN
2079-6382
DOI
10.3390/antibiotics10091047
PMC
PMC8464924
Cited by
13
References
1
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (vor)
Funders
  • Sichuan Province Science and Technology Support Program (2021YFH0188)
  • National Natural Science Foundation of China (81400501)
  • Guiyang Science Plan Project (2018]1-59)
  • Science and Technology Fund of Guizhou Provincial Health Commission (gzwkj2021-341)

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