Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 448

The DOI matches its Crossref record; 198 of the 198 references it cites were found in a registry or an index.

Applications of Lysozyme, an Innate Immune Defense Factor, as an Alternative Antibiotic

Open access
Ferraboschi, Patrizia, Ciceri, Samuele, Grisenti, Paride·2021·Antibiotics
DOI 10.3390/antibiotics10121534
Open this paper in CoChat — free account

Abstract

Lysozyme is a ~14 kDa protein present in many mucosal secretions (tears, saliva, and mucus) and tissues of animals and plants, and plays an important role in the innate immunity, providing protection against bacteria, viruses, and fungi. Three main different types of lysozymes are known: the c-type (chicken or conventional type), the g-type (goose type), and the i-type (invertebrate type). It has long been the subject of several applications due to its antimicrobial properties. The problem of antibiotic resistance has stimulated the search for new molecules or new applications of known compounds. The use of lysozyme as an alternative antibiotic is the subject of this review, which covers the results published over the past two decades. This review is focused on the applications of lysozyme in medicine, (the treatment of infectious diseases, wound healing, and anti-biofilm), veterinary, feed, food preservation, and crop protection. It is available from a wide range of sources, in addition to the well-known chicken egg white, and its synergism with other compounds, endowed with antimicrobial activity, are also summarized. An overview of the modified lysozyme applications is provided in the form of tables.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.3390/antibiotics10121534

Cites

198 of 198 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 198 references

Cited by

See all 448

Metadata

Authors
Ferraboschi, P., Ciceri, S., & Grisenti, P.
Venue
Antibiotics
Publisher
MDPI AG
Published
2021-12-14
Volume
10
Issue
12
Pages
1534
ISSN
2079-6382 (ISSN-L)
DOI
10.3390/antibiotics10121534
OpenAlex
W4200533375
Cited by
448
References
198
FWCI
33.13
Type
journal article
Language
en
Open access
gold

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Applications of Lysozyme, an Innate Immune Defense Factor, as an Alternative Antibiotic. https://app.cochat.ai/papers/10.3390/antibiotics10121534
The paper
Ferraboschi, P., Ciceri, S., & Grisenti, P. (2021). Applications of Lysozyme, an Innate Immune Defense Factor, as an Alternative Antibiotic. Antibiotics. https://doi.org/10.3390/antibiotics10121534

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.