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Cited by 231Mangiferin and Mango ExtractsPhytochemicals and Antioxidant ActivitiesMedicinal Plant Research

Mango (mangifera indica l.) Leaves: nutritional composition, phytochemical profile, and health-promoting bioactivities

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Kumar, Manoj, Saurabh, Vivek, Tomar, Maharishi, Hasan, Muzaffar, Changan, Sushil, Sasi, Minnu, Maheshwari, Chirag, Prajapati, Uma +6 more·2021·Antioxidants
DOI 10.3390/antiox10020299PMC PMC7920260
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Abstract

Mangifera indica L. belongs to the family of Anacardiaceae and is an important fruit from South and Southeast Asia. India, China, Thailand, Indonesia, Pakistan, Mexico, Brazil, Bangladesh, Nigeria, and the Philippines are among the top mango producer countries. Leaves of the mango plant have been studied for their health benefits, which are attributed to a plethora of phytochemicals such as mangiferin, followed by phenolic acids, benzophenones, and other antioxidants such as flavonoids, ascorbic acid, carotenoids, and tocopherols. The extracts from mango leaves (MLs) have been studied for their biological activities, including anti-cancer, anti-diabetic, anti-oxidant, anti-microbial, anti-obesity, lipid-lowering, hepato-protection, and anti-diarrheal. In the present review, we have elaborated on the nutritional and phytochemical profile of the MLs. Further, various bioactivities of the ML extracts are also critically discussed. Considering the phytochemical profile and beneficial effects of the MLs, they can be used as a potential ingredient for the development of functional foods and pharmaceutical drugs. However, more detailed clinical trials still needed to be conducted for establishing the actual efficacy of the ML extracts.

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  • Mango leaf extracts rich in MGF inhibit gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis, Streptococcus pneumoniae) and gram-negative pathogens (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Shigella spp.).

    “Extracts from mango leaves, which are rich in MGF, have shown inhibitory activity against gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis, Streptococcus pneumoniae) and gram-negative pathogens (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Shigella spp.) (114,152,153).”

    From Mangiferin in human disease: Multifaceted mechanisms and applications (Review) (2026) · cites this paper as [152]

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Cited by

Sorted by citations

Authors
Kumar, M., Saurabh, V., Tomar, M., Hasan, M., Changan, S., Sasi, M., Maheshwari, C., Prajapati, U., Singh, S., Prajapat, R. K., Dhumal, S., Punia, S., Amarowicz, R., & Mekhemar, M.
Affiliations
  • ICAR - Central Institute for Research on Cotton Technology (IN)
  • Indian Agricultural Research Institute (IN)
  • Indian Grassland and Fodder Research Institute (IN)
  • Central Institute of Agricultural Engineering (IN)
  • Central Potato Research Institute (IN)
  • Panjab University (IN)
  • Gyan Vihar University (IN)
  • Division of Horticulture, RCSM College of Agriculture, Kolhapur 416004, Maharashtra, India
  • Clemson University (US)
  • InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences (PL)
  • Christian-Albrechts-Universität zu Kiel (DE)
Corresponding author
  • Kumar, Manoj
  • Mekhemar, Mohamed
ORCID
Venue
Antioxidants
Publisher
MDPI AG
Published
2021-02-16
Volume
10
Issue
2
Pages
299
ISSN
2076-3921 (ISSN-L)
DOI
10.3390/antiox10020299
PMC
PMC7920260
OpenAlex
W3132015236
Cited by
231
References
1
Citations by year
2026: 26 · 2025: 63 · 2024: 62 · 2023: 46 · 2022: 22 · 2021: 12
FWCI
8.15
Type
journal article
Language
en
Open access
Licence
Locations
  • Antioxidants (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Multimedialen Archiv und Publikationsserver der Christian-Albrechts-Universität zu Kiel (Christian-Albrechts-Universität zu Kiel) (submittedVersion, cc-by)
Topics
  • Health Sciences › Medicine › Complementary and alternative medicine › Mangiferin and Mango Extracts
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
Keywords
mango leaves, mango, nutritional composition, phytochemical composition, mangiferin, phenolic acids, benzophenone, anticancer activity, antidiabetic activity, antimicrobial activity, anti-obesity, lipid lowering, hepatoprotection, antidiarrheal activity, functional foods, medicinal plants

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