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Cited by 93

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

A Systematic Review on the Role of Vitamin C in Tissue Healing

Bechara, Nada, Flood, Victoria M., Gunton, Jenny E.·2022·Antioxidants
DOI 10.3390/antiox11081605
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Abstract

Vitamin C is an essential nutrient for humans and animals which are unable to synthesise it themselves. Vitamin C is important for tissue regeneration due to the role it plays in collagen formation, and its antioxidant properties. We reviewed the literature to evaluate potential associations between vitamin C supplementation and healing of an acute or chronic condition. Embase, Medline, PubMed, and the Cochrane Library were searched for studies published prior to April 2022. Studies were eligible if they reported at least one association between vitamin C supplementation and healing outcomes. Eighteen studies met the inclusion criteria and were included in this review. Overall, vitamin C supplementation improved healing outcomes in certain pathologies, predominantly pressure ulcers. However, many of the studies had small sample sizes, combined nutritional treatments, and did not test baseline vitamin C. Future studies should be of larger scale, exclusively using vitamin C to determine its role in tissue healing in other wounds. We recommend consideration of vitamin C supplementation for people with pressure ulcers.

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Cites

Research works printed but not linked: 21

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Metadata

Authors
Bechara, N., Flood, V. M., & Gunton, J. E.
Venue
Antioxidants
Publisher
MDPI AG
Published
2022-08-19
Volume
11
Issue
8
Pages
1605
ISSN
2076-3921
DOI
10.3390/antiox11081605
Cited by
93
References
3
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (vor)
Funders
Westmead Charitable Trust

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