Vitamin C: A Comprehensive Review of Its Role in Health, Disease Prevention, and Therapeutic Potential

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Vitamin C for preventing and treating the common cold

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Vitamin C in Human Health and Disease Is Still a Mystery? An Overview

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Antioxidant Vitamin C Improves Endothelial Dysfunction in Chronic Smokers

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Vitamin C-Sources, Physiological Role, Kinetics, Deficiency, Use, Toxicity, and Determination

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Vitamin C in Disease Prevention and Cure: An Overview

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Neuroprotective Effect of Antioxidants in the Brain

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Vitamin C and Infections

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Antioxidative and anti-inflammatory activity of ascorbic acid

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Chemical Stability of Ascorbic Acid Integrated into Commercial Products: A Review on Bioactivity and Delivery Technology

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Ascorbic Acid Enhances Endothelial Nitric-oxide Synthase Activity by Increasing Intracellular Tetrahydrobiopterin

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Bioactive Compounds for Skin Health: A Review

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Pathophysiology of Cardiovascular Diseases: New Insights into Molecular Mechanisms of Atherosclerosis, Arterial Hypertension, and Coronary Artery Disease

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Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) study: a randomized trial of the effect of vitamins E and C on 3‐year progression of carotid atherosclerosis

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Long-Term Vitamin C Treatment Increases Vascular Tetrahydrobiopterin Levels and Nitric Oxide Synthase Activity

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Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials

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High-dose vitamin C enhances cancer immunotherapy

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Intake of vitamin E, vitamin C, and carotenoids and the risk of Parkinson's disease: a meta-analysis

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Immunomodulatory and antimicrobial effects of vitamin C

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Emerging Infectious Diseases

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Global Vitamin C Status and Prevalence of Deficiency: A Cause for Concern?

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Relation of Consumption of Vitamin E, Vitamin C, and Carotenoids to Risk for Stroke among Men in the United States

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Ascorbic Acid (Vitamin C) as a Cosmeceutical to Increase Dermal Collagen for Skin Antiaging Purposes: Emerging Combination Therapies

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A priori–defined dietary patterns are associated with reduced risk of stroke in a large Italian cohort

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Dietary vitamin C in human health

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High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer

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Factors Affecting Vitamin C Status and Prevalence of Deficiency: A Global Health Perspective

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Vitamin C and risk of coronary heart disease in women

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Effect of Antioxidant Vitamin Supplementation on Cardiovascular Outcomes: A Meta-Analysis of Randomized Controlled Trials

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Vitamin C—An Adjunctive Therapy for Respiratory Infection, Sepsis and COVID-19

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Does supplemental vitamin C increase cardiovascular disease risk in women with diabetes?

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Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer

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The antiviral properties of vitamin C

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Effect of vitamin C on endothelial function in health and disease: A systematic review and meta-analysis of randomised controlled trials

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Ascorbic Acid in Plant Growth, Development and Stress Tolerance

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The Emerging Role of Vitamin C as a Treatment for Sepsis

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Pro- and Antioxidant Effects of Vitamin C in Cancer in correspondence to Its Dietary and Pharmacological Concentrations

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Vitamin C

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The Long History of Vitamin C: From Prevention of the Common Cold to Potential Aid in the Treatment of COVID-19

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Vitamin C and Cardiovascular Disease: An Update

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Intake of antioxidant vitamins and risk of death from stroke in postmenopausal women

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Factors that impact the stability of vitamin C at intermediate temperatures in a food matrix

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Anti-diabetic effects of natural antioxidants from fruits

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Therapeutic Perspective of Vitamin C and Its Derivatives

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The role of vitamin C in stress-related disorders

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Antioxidant vitamins intake and the risk of coronary heart disease: meta-analysis of cohort studies

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Structure, extraction, processing, and applications of collagen as an ideal component for biomaterials - a review

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Serum Vitamin C Concentration Was Inversely Associated With Subsequent 20-Year Incidence of Stroke in a Japanese Rural Community

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Reprogramming the epigenome with vitamin C

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Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the European Prospective Investigation into Cancer–Norfolk prospective population study

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Vitamins as Antioxidants

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Effect of Vitamin C on the Availability of Tetrahydrobiopterin in Human Endothelial Cells

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Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer

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Scurvy: reemergence of nutritional deficiencies.

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The Discovery of Vitamin C

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Supplemental Vitamins and Minerals for Cardiovascular Disease Prevention and Treatment

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Total Antioxidant Capacity of the Diet Is Associated with Lower Risk of Ischemic Stroke in a Large Italian Cohort,

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Vitamin C Intake, Circulating Vitamin C and Risk of Stroke: A Meta‐Analysis of Prospective Studies

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Benefits of Vitamins in the Treatment of Parkinson’s Disease

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Neurobiology of vitamin C: Expanding the focus from antioxidant to endogenous neuromodulator

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Nuclear and Cytoplasmic Functions of Vitamin C

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Collagen Structure-Function Mapping Informs Applications for Regenerative Medicine

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A Systematic Review on the Role of Vitamin C in Tissue Healing

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Auranofin/Vitamin C: A Novel Drug Combination Targeting Triple-Negative Breast Cancer

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Vitamin C supplementation for the primary prevention of cardiovascular disease

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Ascorbic acid supplementation improves postprandial glycaemic control and blood pressure in individuals with type 2 diabetes: Findings of a randomized cross‐over trial

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Multiple Effects of Ascorbic Acid against Chronic Diseases: Updated Evidence from Preclinical and Clinical Studies

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Dietary Antioxidants and Parkinson’s Disease

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Possible application of high-dose vitamin C in the prevention and therapy of coronavirus infection

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Effect of High-dose Vitamin C Combined With Anti-cancer Treatment on Breast Cancer Cells

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Cardiovascular Disease: An Introduction

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Scurvy: Rediscovering a Forgotten Disease

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Vitamin C: The next Step in Sepsis Management?

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Therapeutic Use of Vitamin C in Cancer: Physiological Considerations

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Vitamin C: A Review on its Role in the Management of Metabolic Syndrome

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From Conventional Therapies to Immunotherapy: Melanoma Treatment in Review

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High-Dose Vitamin C for Cancer Therapy

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Dietary and circulating vitamin C, vitamin E, β-carotene and risk of total cardiovascular mortality: a systematic review and dose–response meta-analysis of prospective observational studies

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The potential role of vitamin C in empowering cancer immunotherapy

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The Role of Vitamin C in Cancer Prevention and Therapy: A Literature Review

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Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study

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Pneumonia—Overview

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Subcellular Biochemistry

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Vitamin C in plasma is inversely related to blood pressure and change in blood pressure during the previous year in young Black and White women

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A Randomized, Open-Label, Multicenter, Phase 3 Study of High-Dose Vitamin C Plus FOLFOX ± Bevacizumab versus FOLFOX ± Bevacizumab in Unresectable Untreated Metastatic Colorectal Cancer (VITALITY Study)

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A quantitative meta-analysis of vitamin C in the pathophysiology of Alzheimer’s disease

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Factors Affecting the Vitamin C Dose-Concentration Relationship: Implications for Global Vitamin C Dietary Recommendations

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A comprehensive review and recent advances of vitamin C: Overview, functions, sources, applications, market survey and processes

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Fructose and Vitamin C Intake Do Not Influence Risk for Developing Hypertension

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Vitamin C Intake and Cancers: An Umbrella Review

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Preventive and Therapeutic Potential of Vitamin C in Mental Disorders

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Effectiveness of Some Vitamins in the Prevention of Cardiovascular Disease: A Narrative Review

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Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial

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Association Between Plasma Vitamin C Concentrations and Blood Pressure in the European Prospective Investigation Into Cancer-Norfolk Population-Based Study

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Vitamin C Deficiency and Scurvy Are Not Only a Dietary Problem but Are Codetermined by the Haptoglobin Polymorphism

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Effect of dietary vitamins C and E on the risk of Parkinson's disease: A meta-analysis

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Vitamin C deficiency: more than just a nutritional disorder

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Ascorbic acid alleviates toxicity of paclitaxel without interfering with the anticancer efficacy in mice

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Ascorbic acid deficiency impairs wound healing in surgical patients: Four case reports

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Vitamin C and Infectious Diseases

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Vitamin C supplementation reduces the odds of developing a common cold in Republic of Korea Army recruits: randomised controlled trial

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Repositioning Vitamin C as a Promising Option to Alleviate Complications associated with COVID-19

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Nutrition and Immunity

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Associations Between Vitamins C and D Intake and Cartilage Composition and Knee Joint Morphology Over 4 Years: Data From the Osteoarthritis Initiative

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Biomolecular and cellular effects in skin wound healing: the association between ascorbic acid and hypoxia-induced factor

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Synergistic Effect of Vitamin C with Cisplatin for Inhibiting Proliferation of Gastric Cancer Cells

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Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression

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Vitamin C Supplementation in the Treatment of Autoimmune and Onco-Hematological Diseases: From Prophylaxis to Adjuvant Therapy

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Vitamin C Supplementation Improves Blood Pressure and Oxidative Stress after Acute Exercise in Patients with Poorly Controlled Type 2 Diabetes Mellitus

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Vitamin C and Cancer: The Role of Vitamin C in Disease Progression and Quality of Life in Cancer Patients

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Scurvy: A Disease not to be Forgotten

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Clinically proven natural products, vitamins and mineral in boosting up immunity: A comprehensive review

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Vitamin C in Human Health and Disease

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High-Dose Intravenous Vitamin C Combined with Docetaxel in Men with Metastatic Castration-Resistant Prostate Cancer: A Randomized Placebo-Controlled Phase II Trial

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Vitamin C supplementation for the treatment of osteoarthritis: perspectives on the past, present, and future

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Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis

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Tetrahydrobiopterin, L-Arginine and Vitamin C Act Synergistically to Decrease Oxidative Stress, Increase Nitric Oxide and Improve Blood Flow after Induction of Hindlimb Ischemia in the Rat

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The sour side of vitamin C might mediate neuroprotective, anticonvulsive and antidepressant-like effects

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More than just teeth: How oral health can affect the heart

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Understanding Vitamin C: Comprehensive Examination of Its Biological Significance and Antioxidant Properties

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Taking 200 mg Vitamin C Three Times per Day Improved Extraction Socket Wound Healing Parameters: A Randomized Clinical Trial

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The Discovery and Chemistry of Vitamin C

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Exploring the causality between ankylosing spondylitis and atrial fibrillation: A two-sample Mendelian randomization study

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Vitamin C

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Circulating vitamin C and the risk of cardiovascular diseases: A Mendelian randomization study

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Synergistic Effect of Vitamin C with Superparamagnetic Iron Oxide Nanoparticles for Inhibiting Proliferation of Gastric Cancer Cells

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Intravenous vitamin C for vasoplegia: A double-blinded randomised clinical trial (VALENCIA trial)

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Vasoplegic Syndrome and Anaesthesia: A Narrative Review

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Collagen-Based Therapies for Accelerated Wound Healing

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Lessons learned from “the great mimicker disease”: A retrospective study of 18 patients with scurvy

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Hydrophilic Vitamins in Health and Disease

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The Association Between Vitamin C and Cancer: A Two-Sample Mendelian Randomization Study

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Vitamin C Promotes Wound Healing: The Use of in Vitro Scratch Assays to Assess Re-Epithelialization

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Analysis of High-Dose Ascorbate-Induced Cytotoxicity in Human Glioblastoma Cells and the Role of Dehydroascorbic Acid and Iron

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Applications of Nanotechnology-Based Drug Delivery System for Delivering Natural Products into Acute and Chronic Wounds: A Review

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Dietary and supplementary vitamin C intake and the risk of lung cancer: A meta‑analysis of cohort studies

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Scurvy: A Rare Disease or a Rare Diagnosis?

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Collagen Involvement in Health, Disease, and Medicine

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Albert Szent-Györgyi—The Scientist Who Discovered Vitamin C

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Novel Compatible Silver Nanoparticles Functionalized by Vitamin C and its Derivatives: Characterization and their antibacterial Activity against Escherichia coli and Staphylococcus aureusPreprint

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The Effects of Topical Vitamin C on Burn Wound Healing

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Effects of Ascorbic Acid, Dehydroascorbic Acid and Methotrexate on Breast Cancer Cell Viability

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Natural Products for Improving Soft Tissue Healing: Mechanisms, Innovations, and Clinical Potential

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Preparation and characterization of Ag@MOF-Amomum tsaoko essential oil/waterborne polyurethane composite films for strawberry preservation

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The unmet promise: a critical review of antioxidant strategies in myocardial ischemia-reperfusion injury and the path towards precision medicine

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Vitamin C in fruits and vegetables: stability, processing effects, analytical detection, nutrient interactions, bioavailability, and health implications

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Bioactive Compounds and the Performance of Proteins as Wall Materials for Their Encapsulation

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Interactions of the molecular assembly of protein as encapsulation materials: A review

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Vitamin C conveys geroprotection on primate ovaries

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Oxidative stress and antioxidant therapeutics in autism spectrum disorder: a biochemical and structure–activity relationship perspective

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Carbon dots and metal–organic frameworks based nanohybrids for improved biosensing and biomedical applications

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Relationships between vitamin C intake and COPD assessed by machine learning approaches from the NHANES (2017–2023)

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Melatonin Boosts the Phytochemical Profile of Blood Oranges, Enhancing (Poly)phenol and Endogenous Melatonin Content, Through Pre‐ and Postharvest Treatments

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Next-Generation Antioxidants in Cardiovascular Disease: Mechanistic Insights and Emerging Therapeutic Strategies

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From nutrients to health outcomes: integrating diet, disease risk, and lifelong wellness

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The Seven Methods for the Evaluation of Nutritional Status—ABCDEFG: Narrative Review

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Potassium bromate-induced oxidative damage and nephrotoxicity in rats is ameliorated by vitamin C

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Protective roles of α-tocopherol, α-CEHC, and gallic acid against CO3•−-induced DNA damage and their effect on OGG1 and pro-oxidant enzymes

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Ginseng Oligopeptides Promote Longevity and Enhance Stress Resistance in Caenorhabditis elegans via the DAF-16/FOXO Pathway

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Vitamin C Stability in Fruit Juices: Impact of Non-Thermal Processing on Nutritional Quality and Safety

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Oxidative stress in chronic disease: Mechanisms, therapeutic strategies, and future directions

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Development of a new calibration method for study and elimination of interference effects on the example of determining ascorbic acid in juices by chromatographic technique

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Comparative effectiveness of oral nutritional supplements in preventing respiratory tract infections among adults: a systematic review and network meta-analysis

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Possible role of vitamins C and E co-administration in the prevention of testicular ischemia–reperfusion injury following surgical repair of torsion of the testis

Ogunleye, O. D., Afolabi, O. A., Saka, W. A., Olusola, B. O., Ajike, R. A., Oladokun, O. O., Hammed, O. S., Hezekiah, O. S., & Adedeji, O. J. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1660240 · Cited by 4 · see citing works

Valorisation of Citrus sinensis peel biomass into functional slice jam: Optimisation using central composite design and quality characterisation

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Edible oils as bio-plasticisers for sustainable additive manufacturing: comparative electrochemical performance and sensing of ascorbic acid in juices

Oliveira, A. C., Bernalte, E., Moumen, Z., Augusto, K. K. D. L., Khan, M. A., Muñoz, R. A. A., Crapnell, R. D., & Banks, C. E. (2025) · Food Chemistry · doi:10.1016/j.foodchem.2025.147111 · Cited by 4 · see citing works

Problems associated with the ATC system of drug classification

Bindel, L. J., & Seifert, R. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04833-1 · Cited by 5 · see citing works

Effects of ascorbic acid and cholecalciferol on growth factor release, cytokines, and biomechanical properties of platelet rich fibrin: in vitro study

Özcan, M., Topcu, B. E., Alkaya, B., Yılmaz, M. B., Türer, O. U., & Haytac, M. C. (2026) · BMC Oral Health · doi:10.1186/s12903-025-07620-9 · Cited by 4 · see citing works

Collagen Mechanics

Szarek, P., & Ruberti, J. W. (2026) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-032-05273-5_10 · Cited by 4 · see citing works

Vitamin C improves 28-day survival in patients with sepsis-associated acute kidney injury in the intensive care unit: a retrospective study

He, Y., & Liu, J. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1600224 · Cited by 4 · see citing works

Effect of fruit ripening stage on glycemic index, glycemic load and antioxidant properties in healthy subjects: implications for the nutritional management of diabetes

Yapo, B. F., Doué, G. G., Dakia, P. A., Kouadio, Y. H., Disseka, W. K., Gbakayoro, J.-B., & Brou, K. (2025) · Applied Food Research · doi:10.1016/j.afres.2025.101177 · Cited by 3 · see citing works

Integration of gold nanoparticles into SnS for enhanced peroxidase-like activity and colorimetric detection of ascorbic acid in fruit juice

Truong, C.-T.-N., Le, V., Doan, V., Tran, V.-T., Kim, T. T., Giang, T. T. H., Pham, T.-D., Nguyen, C.-H., Tu, N. T. T., & Nguyen, T. (2025) · RSC Advances · doi:10.1039/d5ra05712d · Cited by 3 · see citing works

Bio macromolecular stabilization of Lacticaseibacillus paracasei and Lactiplantibacillus plantarum : A comparative study of cryoprotection, shelf stability, and metabolic recovery

Kanimozhi, N. V., & Sukumar, M. (2025) · Food biomacromolecules. · doi:10.1002/fob2.70030 · Cited by 3 · see citing works

Antioxidant Capacity and Polyphenolic Profile of Extractable and Non-Extractable Fractions of Traditional Mediterranean Diet Recipes from Different Regions

Cuenca-Ortolá, M., Gandía, M., Chaji, S., Mossaid, F. Z. E., Ennahli, S., Ajal, E. A., Filice, S., Ammar, A., Gamero, A., & Cilla, A. (2026) · Antioxidants · doi:10.3390/antiox15030377 · Cited by 3 · see citing works

Valproic Acid Enhances the Anticancer Effect of L-Ascorbic Acid by Upregulating Sodium-Dependent Vitamin C Transporter 2 in Colorectal Cancer

Kawalin, K., Diva, H. M., Ho, P. T. B., Lee, A., Kiba, M., Lee, M. K., Kang, H. G., Park, E., Lee, S., & Lee, S. (2025) · Antioxidants · doi:10.3390/antiox14070864 · Cited by 3 · see citing works

Rational Design of PCR12mod6, a Cathelicidin-HR-Derived Peptide with Enhanced Dual-Action Antimicrobial and Antioxidant Activity

Tankrathok, A., Karnmongkol, C., Kamlaiwong, P., Srisamoot, N., Wiriyaampaiwong, P., & Jangpromma, N. (2025) · ACS Omega · doi:10.1021/acsomega.5c03658 · Cited by 2 · see citing works

Dual-functional nitrogen-doped carbon dot/copper oxide nanocomposites for electrochemical sensing of ascorbic acid and antimicrobial applications

Robi, Z. H., Nemera, D. J., Gebremichael, T. E., & Muleta, G. G. (2025) · BMC Chemistry · doi:10.1186/s13065-025-01639-3 · Cited by 2 · see citing works

Enhancing ascorbic acid delivery and stability by yeast microencapsulation in vitro and food matrices: A comparative study of Candida, and Kluyveromyces species.

Karaman, K. (2025) · Food Research International · doi:10.1016/j.foodres.2025.117985 · Cited by 2 · see citing works

Examining the association between the Mediterranean diet and depression: a cross-sectional study in Lebanon

Sater, R. F. A., Younes, R. S., & Julien, S. G. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1692981 · Cited by 2 · see citing works

Oxidative Stress Biomarkers: Molecular Mechanisms, Detection Techniques, and Clinical Applications: A Comprehensive Review

Qadir, A. M., & Omer, R. A. (2026) · Journal of Analytical Chemistry · doi:10.1134/s1061934825701357 · Cited by 2 · see citing works

Recent advances in tendon redox biology: the interplay of oxidative stress, calcium signaling, and antioxidant defence mechanisms

Tang, Y., Alhaskawi, A., Ruan, B., & Yuan, Z. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1752491 · Cited by 2 · see citing works

Hepato-Protective Effect of Pomegranate and Persimmon Juices Against Oxidative Stress and Inflammation in Cyclosporine-Induced Cholestasis in Rats

Mohamed, R. S., & Fouda, K. A. (2026) · Foods · doi:10.3390/foods15091473 · Cited by 2 · see citing works

Vitamin C Regulates Redox Homeostasis and Mitigates Potassium Bromate‐Induced Oxidative Injury to Rat Intestine

Nazir, S., Ahmad, M. K., & Zubair-Ul-Nazir (2026) · Environmental and Molecular Mutagenesis · doi:10.1002/em.70045 · Cited by 2 · see citing works

Influence of Solvent and Ultrasound-Assisted Extraction on the UV Spectral Profiles of Extracts from Agro-Waste

Lukavski, T., Šarčević, I., & Vukoje, M. (2026) · Sci · doi:10.3390/sci8050096 · Cited by 2 · see citing works

Synergistic effects of vitamins and plant polyphenols on epigenetic regulation of aging

Addissouky, T. A. (2026) · Egyptian Journal of Medical Human Genetics · doi:10.1186/s43042-026-00893-x · Cited by 2 · see citing works

Ascorbate Recycling as a Molecular Redox Capacitor: A Sulfur-Centered Perspective on Dehydroascorbate Reduction in Biological Systems

Heshiki, R., Mizumoto, K. B., Naomasa, R. F., Matsumura, T., & Yamasaki, H. (2026) · Cells · doi:10.3390/cells15151391 · Cited by 2 · see citing works

Micronutrients and Food Fortification

Ashraf, S. A., Banu, H., Alcantra, J. C., & Ibrahim, N. A. (2025) · Springer eBooks · doi:10.1007/978-981-95-1217-1_4 · Cited by 2 · see citing works

A Digital Image Analysis of the Morphology and Immunolocalization of Catalase and Caspase-3 in the Skin of Adult Male Rats After Treatment with Letrozole and Vitamin C

Pilutin, A., Łukasiewicz, J., Rzeszotek, S., Misiakiewicz-Has, K., & Wilk, A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26178645 · Cited by 1 · see citing works

Harnessing Vitamin C: Unveiling Its Potential in Cancer Prevention and Treatment

Roy, A., Maiti, D. K., & Banik, B. K. (2025) · Current Medicinal Chemistry · doi:10.2174/0109298673411854250808061949 · Cited by 1 · see citing works

Vitamin C in Pregnancy: A Key Modulator of Fetal Growth and Epigenetic Stability

Ersoy, B., & Karadağ, M. G. (2025) · Current Nutrition Reports · doi:10.1007/s13668-025-00708-2 · Cited by 1 · see citing works

Ascorbate formulation promotes wound healing in goat model: Insights into molecular dynamics through cytokine modulation and angiogenic marker expression

Sharma, A. K., Kalonia, A., Shukla, A., Shaw, P., Choudhury, S., Vats, D., Anand, M., Prabhu, S. N., Vaswani, S., & Shukla, S. K. (2025) · Tissue and Cell · doi:10.1016/j.tice.2025.103218 · Cited by 1 · see citing works

Comparative bioactive compounds in the leaves, petals, and hips of two wild rose species: Persian yellow rose (Rosa foetida Herrm.) and dog rose (Rosa canina L.)

Nazari, N., Naderi, R., Nazeri, V., & Nazari, F. (2025) · Ornamental Horticulture · doi:10.1590/2447-536x.v31.e312986 · Cited by 1 · see citing works

Protective Functions of β-Alanyl-L-Histidine and Glycyl-L-Histidyl-L-Lysine Glycoconjugates and Copper in Concert

Николаевна, Н. И., & Rizzarelli, E. (2025) · Antioxidants · doi:10.3390/antiox14121512 · Cited by 1 · see citing works

Amelioration of Ethanol-Induced Gastric Ulcer in Rats by Tilapia Skin Derived Collagen And/or Vitamin C: Implication of NFκB/TNFα and BAX/Bcl-2 Pathways

Elbialy, Z. I., Salah, A. S., Elsayes, N. A., Assas, M. A., Abdel-Sattar, E. A., Abdelatty, A., Wakeel, R. A. A., & Assar, D. H. (2025) · International Journal of Peptide Research and Therapeutics · doi:10.1007/s10989-025-10759-2 · Cited by 1 · see citing works

Impact of azoxystrobin exposure on sperm morphology, antioxidant defense, reproductive hormones, and testicular histopathology in mice

Harkesh, R., & Geeta, P. (2025) · Asian Pacific Journal of Reproduction · doi:10.4103/apjr.apjr_209_24 · Cited by 1 · see citing works

Nutritional immunology in lifespan

Fallah, M., Naeini, F., Fahimzad, F. S., Nouri, A., Manesh, S. M. R., Haghighi, A., & Ebrahimpour‐Koujan, S. (2025) · Experimental Gerontology · doi:10.1016/j.exger.2025.113015 · Cited by 2 · see citing works

Vitamins A, E, and C: Mechanisms of Antioxidant Action and Physiological Impact

Koca, F., Yılmaz, E., & Çimen, L. (2025) · Sağlık Bilimleri Dergisi · doi:10.34108/eujhs.1727061 · Cited by 1 · see citing works

Hepatoprotective effect of chitosan-vitamin C based hydrogel on alpha-Naphthylisothiocyanate-induced cholestasis in infant rats

Qutb, S. A., Saad, D. Y., & Mohamed, A. S. (2025) · Tissue and Cell · doi:10.1016/j.tice.2025.103307 · Cited by 1 · see citing works

An Overview of Natural Antioxidant Pharmacodynamics and Pharmacokinetics

Moni, S. S. (2026) · Springer eBooks · doi:10.1007/978-981-95-3758-7_13 · Cited by 1 · see citing works

Machine learning and SHAP-based interpretation of dietary antioxidants’ impact on comorbid MDD and suicidal ideation

Xu, Z., Wang, J., Chang, T., Li, Y., Jia, H., & Zhang, X. (2026) · Journal of Affective Disorders · doi:10.1016/j.jad.2026.121252 · Cited by 1 · see citing works

Botulinum Toxin Effects and Its Association with Vitamin and Mineral Supplementation: A Narrative Review

Puizina, E., Martinović, D., Lasić, S., Martinovic, L., Puizina, J., Dediol, E., Lupi-Ferandin, S., & Božić, J. (2026) · Nutrients · doi:10.3390/nu18030491 · Cited by 1 · see citing works

Impact of Mediterranean diet adherence on quality of life in patients with multiple sclerosis: A prospective study

Hedfi, I., Baradhi, N., Ayed, M., Jemai, C., Mami, F. B., Ali, Z. H., Laajili, O., Zouari, M., Sassi, S. B., & Htira, Y. (2026) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2026.102974 · Cited by 1 · see citing works

A Thorough Analysis of Ascorbic Acid's Therapeutic Benefits and Potential Toxicological Effects

Tiwari, A., Mandal, S., & Samal, P. K. (2026) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.70779 · Cited by 1 · see citing works

Regulation of ascorbic acid metabolism in postharvest navel orange fruit during storage by exogenous hydrogen sulfide

Lv, D., Huang, T., Li, Y., Zuo, X., Wang, J., Cai, Z., Shen, Y., Du, H., Zhang, W., Liu, Z., et al. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1760332 · Cited by 1 · see citing works

Antioxidant, anti-inflammatory, and immunomodulatory pathways of Citrus limon juice in a respiratory-irritated rat model.

Algheshairy, R. M., & Ali, H. A. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1743575 · Cited by 1 · see citing works

Controlled light intensity efficiently enhances micronutrient content and composition in chia sprouts

Bermejo, N. F., Willems, K., & Munné‐Bosch, S. (2026) · Food Chemistry · doi:10.1016/j.foodchem.2026.149376 · Cited by 1 · see citing works

The Role of Vitamins in Preconception Care and Infertility Treatment: A Narrative Review

Ota, K., & Takahashi, T. (2026) · Reproductive Medicine and Biology · doi:10.1002/rmb2.70068 · Cited by 1 · see citing works

A Healthy Lifestyle Can Slow Immune System Aging and Reduce Age-Related Chronic Inflammation: A Narrative Review

Cakala, M., Domaszewska-Szostek, A., & Puzianowska‐Kuźnicka, M. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27125605 · Cited by 2 · see citing works

A systematic review on the role of high-dose vitamin C in trauma patients

Patel, N. C., Coombs, C., Bage, T., & Ramasamy, A. (2026) · BMJ Military Health · doi:10.1136/military-2026-003285 · Cited by 1 · see citing works

Phytochemical–Mechanistic Integration and Nano‐Enabled Strategies in Herbal Dermatology: Toward Targeted and Translational Therapeutics

Karunakaran, S., Sundarraj, D., Velu, P., Gunasekar, Y. S., Kumaresan, Y., & Dinakarkumar, Y. (2026) · ChemistrySelect · doi:10.1002/slct.73771 · Cited by 1 · see citing works

Evaluation of the nutritional and bioactive composition of peanut by-products: peanut skins obtained after roasting

Santara, B., Kaboré, K., Sanou, D. O., Ouedraogo, A., Ouaro, D., Sawadogo, A., Dabiré, C., Coulibaly, O., Konaté, K., & Dicko, M. H. (2026) · International Journal of Food Science & Technology · doi:10.1093/ijfood/vvag145 · Cited by 1 · see citing works

Ultrafiltered Mulberry (Morus alba L.) Leaf Albumin-Type Protein Attenuates High-Fat Diet-Induced Obesity in Mice by Remodeling Gut Microbiota and Metabolic Homeostasis

Yu, L., Luo, K., He, D., Yu, G., Yu, Y., Yao, H. L., Sun, C., & Wu, X. (2026) · Foods · doi:10.3390/foods15162774 · Cited by 1 · see citing works

Oxidative balance-related metabolite signature and incident cardiovascular disease and type 2 diabetes within the PREDIMED trial

Goñi, L., Fernández-Duval, G., Razquín, C., Toledo, E., Clish, C. B., Liang, L., Babió, N., Asensio, E. M., Castro‐Barquero, S., Li, J., et al. (2026) · Metabolism · doi:10.1016/j.metabol.2026.156763 · Cited by 2 · see citing works

Nephroprotective effects of Rhodomyrtus tomentosa in 7,12-Dimethylbenz[a]anthracene (DMBA)-Induced Nephrotoxicity: Computational and physiological analysis of cytokine expression

Situmorang, P. C., Wibowo, S., Sari, R. M., Nugraha, A. P., Ibrahim, A., Fitrianita, A., Abiyyu, N., Ilyas, S., & Syahputra, R. A. (2025) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2025.102155 · Cited by 1 · see citing works

Experimental and clinical evidence on anti-inflammatory, antioxidant, and immunomodulatory effects of vitamin C: an updated and comprehensive review

Kianian, F., Gholami, A. A., Ghalibaf, M. H. E., Marefati, N., Boskabady, M., & Boskabady, M. H. (2026) · Journal of Functional Foods · doi:10.1016/j.jff.2026.107440 · Cited by 1 · see citing works

Can Vitamin C Intake and Physical Activity Individually and Jointly Lower Inflammation in Chronically Infected Populations? Insights from NHANES 2005–2018Preprint

Zhou, H., Zhang, H., Huang, Y., & Hu, Y. (2025) · Research Square · doi:10.21203/rs.3.rs-6641016/v1

Individual and joint associations of vitamin C intake and physical activity with inflammation and mortality in chronically infected populations: Evidence from a cohort study of NHANES 2005 to 2018

Zhou, H., Zhang, H., Huang, Y., & Hu, Y. (2025) · Medicine · doi:10.1097/md.0000000000044555

Impaired healing following implant placement surgery: A case report of a modern‐day manifestation of scurvy

Zafiropoulos, G., Kolb, G., & Tatakis, D. N. (2025) · Clinical Advances in Periodontics · doi:10.1002/cap.70013

Tannic acid suppresses vitamin C’s hormetic effects in HCT-15 low-SVCT2-expressing colorectal cancer cells by upregulating SVCT2

Kawalin, K., Diva, H. M., Ho, P. T. B., Lee, M.-G., Kang, H. G., Lee, T., & Lee, S. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118701

Formation and Regulation Mechanism of Ascorbic Acid in Sweet Pepper and Chili Pepper at Different Growth Stages

Zhang, Z., Li, X., Zhang, H., Yu, Z., Fan, Y., Meng, Y., & Yan, L. (2025) · Foods · doi:10.3390/foods14213675

Neurodevelopmental Changes in the Guinea Pig Brain Caused by Time-Limited Complete Vitamin C Deprivation

Čapo, I., Andrijević, I., Čapo, N., Popović, M., Milenković, I., Ratajac, R., Vranješ, D., Milutinović, D., Simin, D., & Sekulić, S. (2025) · Nutrients · doi:10.3390/nu17213484

Role of vitamin C infusion in postoperative mechanically ventilated neonates with sepsis: a randomized controlled trial

Elmesiry, A., El-Sheikh, M. R., Elshimy, K. M., & Abotaleb, A. M. (2025) · European Journal of Pediatrics · doi:10.1007/s00431-025-06625-4

The Interplay Between Redox Imbalance, Inflammatory Signaling and Mechanical Factors in Tendon Recovery

Yılmaz, S., Ateş, Ş., Uçar, S., & Yılmaz, F. (2025) · Bratislavské lekárske listy/Bratislava medical journal · doi:10.1007/s44411-025-00440-x

Emerging Role of Tet2 in the Regulation of Vascular Smooth Muscle Cell Identity During Arterial Calcification

Piollet, M., & Cochain, C. (2025) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2025.101451

Association between vitamins intake and kidney stone: A cross-sectional study

Li, D., & Li, S. (2025) · Medicine · doi:10.1097/md.0000000000046495

DETERMINATION OF VITAMIN LEVELS IN THE “AS RHEUM” FOOD SUPPLEMENT BASED ON RHUBARB AND WILD GARLIC (JUSAI) USING THE HPLC METHOD

Abdulloyev, S. X., & Xolmatova, M. A. (2025) · Journal of Chemistry of Goods and Traditional Medicine · doi:10.55475/jcgtm/vol4.iss5.2025.568

Physicochemical, ultrasonic, transport and UV spectral investigations of l-ascorbic acid in aqueous [Bmim][Cl]/[Bmim][BF4] media at several temperatures and concentrations

Mohan, B., Richu, Kumar, A., & Kumar, A. (2025) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2025.129209

GULO Evolution in Bats: A Genomic Approach

Vieira, C. P., López-Fernández, H., Reboiro‐Jato, M., & Vieira, J. (2026) · Lecture notes in networks and systems · doi:10.1007/978-3-032-10634-6_2

Interactive effects of salinity and melatonin on growth, antioxidant defense, and nutrient composition of radish microgreensPreprint

Ghanbari, F. (2026) · Research Square · doi:10.21203/rs.3.rs-8103943/v1

Beyond the Follicle: A Narrative Review on How Systemic Diseases and Drugs Affect Alopecia

Bose, D., Bellani, D., Patil, R., Jamasbi, K., Kapoor, R., & Shome, D. (2026) · Pharmaceutical Medicine · doi:10.1007/s40290-025-00600-y

Chemical Composition of Boswellia Dalzielli Leaf and Characterisation of Its Magnetite (Fe3O4) NanoparticlePreprint

Arowora, K. A., Yohanna, E. R., Umaru, I. J., & Ikwebe, J. (2026) · Research Square · doi:10.21203/rs.3.rs-8411419/v1

The adverse effects of persistent wound stress on patients with type 2 diabetes. Part 2: Therapeutic strategies and tissue engineering approaches

Gao, C., Cai, X., Li, J., Jiang, J., Bo, Q. I. A. N., Yang, R., & Xiong, F. (2026) · Burns · doi:10.1016/j.burns.2026.107875

OBTENÇÃO E SECAGEM POR LEITO DE ESPUMA DE SUCO DESIDRATADO DE CLADÓDIOS DE PALMA SABORIZADO COM POLPA DE MARACUJÁ DO MATO

Oliveira, G. S., Bomfim, D. S., Viana, E. B. M., de Souza, C. C. E., & Zanuto, M. E. (2026) · Revista Contemporânea · doi:10.56083/rcv6n1-100

Insights into the host response to ‘dormant’ Mycobacterium tuberculosis utilizing ‘Vitamin C-induced dormant Mtb’ THP-1 cell infection model

Kumari, K., Batra, S. D., Sikri, K., & Tyagi, J. S. (2026) · BMC Genomics · doi:10.1186/s12864-026-12544-x

A state-of-the-art in exploring microalgal vitamins: Advancements in production, extraction, market potential, applications, and perspectives for a sustainable future

Maity, S., & Yadav, A. K. (2026) · Preparative Biochemistry & Biotechnology · doi:10.1080/10826068.2026.2625200

Vitamin C in the Treatment of Colorectal Cancer: Between Hope and Despair

Wasmer, M., Weber, M., & Faes, S. (2026) · Cancers · doi:10.3390/cancers18040654

3D Plasmonic Ag Nanodendrites as Highly Efficient SERS Substrates for Ultra-Trace Detection of Ascorbic Acid

Murugan, D., Sharma, A., Saxena, S., Daukiya, L., Sarkar, D., Saxena, S. K., Kumar, V., & Shrivastav, A. M. (2026) · ACS Applied Optical Materials · doi:10.1021/acsaom.5c00648

Blood Profile, Productivity and Carcass Pieces of Super Superior Kampung Chicken Supplemented with Vitamin C, Vitamin E, Selenium Infected with Escherichia coli

Mudawaroch, R. E., Iskandar, F., Azzahra, F. M., & Rizquna, U. M. (2026) · Jurnal Penelitian Pendidikan IPA · doi:10.29303/jppipa.v12i2.14308

Scurvy mimicking cerebral palsy progression: severe vitamin C deficiency and functional recovery in a child with spastic diplegia. A case report

Fernanda, G. B., Hanindita, M. H., Irmawati, M., & Gunawan, P. I. (2026) · CHILD`S HEALTH · doi:10.22141/2224-0551.21.1.2026.1940

Bi2O3@Zn–Al–layered double hydroxide/graphene oxide nanocomposite-based electrochemical sensor for the determination of ascorbic acid in biological samples

Khoshnoud, M., Shahvandi, S. K., Ghaedi, M., Javadian, H., parkook, F., & Banks, C. E. (2026) · Materials Chemistry and Physics · doi:10.1016/j.matchemphys.2026.132344

Nano-armoured Vitamin C: A novel approach to micronutrient delivery and natural food preservation in integrated food systemsPreprint

Antony, C., & Narayanaswamy, K. (2026) · Research Square · doi:10.21203/rs.3.rs-8801688/v1

UHPLC-QTOF-IMS-based phytochemical profiling, in-vitro simulated gastrointestinal digestion, and antimicrobial and cytoprotective potential of Prunus cerasoides fruit extract against gastrointestinal pathogens

Kumar, S., Hegde, A. S., Srivatsan, V., & Padwad, Y. S. (2026) · Food Research International · doi:10.1016/j.foodres.2026.119025

A Narrative Overview of Vitamin C: Roles in Well-being and Disease

Alam, A., Pandey, S. N., Devi, S., & Dhankhar, N. (2025) · Current Functional Foods · doi:10.2174/0126668629374203250917172028

Role of Vitamin C in Health and Disease: A Comprehensive Review

Bordia, H., Lakhawat, S. S., Shekhawat, P., Joshi, K., & Saini, A. K. (2025) · Advances in Applied Biological Research · doi:10.48165/aabr.2025.2.1.01

Effects of Vitamin C on health: a review of evidence

Bei, R. (2013) · Frontiers in bioscience · doi:10.2741/4160 · Cited by 259 · see citing works

Vitamin C: Properties, Physiology, and Health Effects

Chang, S. K., & Chan, K. S. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-40344-6.00096-x

فيتامين ج كعامل علاجي ووقائي

Waheed, N. A., Waheed, S. A., & Al-Dulaimi, A. (2024) · Al-Bayan Journal for Medical and Health Sciences